Patents Examined by Michael P Cohen
  • Patent number: 11864555
    Abstract: The disclosure relates to systems, compositions and methods for providing nutrients, root proliferants, crop protection agents and other crop inputs for a plant. The disclosure also relates to methods for increasing the uptake of a crop active compound into a growing plant.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: January 9, 2024
    Assignees: PIONEER HI-BRED INTERNATIONAL, INC., CORTEVA AGRISCIENCE LLC
    Inventors: Marios Avgousti, Robert Ray Burch, John D Everard, Rajeev L Gorowara, Gary Delmar Jaycox, Shane Francis Kendra, Jacy Cameron Macchia, Ning Wang, Jihua Zhang
  • Patent number: 11849723
    Abstract: A dispersion includes a zinc oxide component, and an aromatic polyol which is represented by Formula (I) and which has terminal hydroxyl groups that form chelating bonds with zinc atoms of the zinc oxide component, wherein p and q are independently integers ranging from 1 to 40. A method for preparing the dispersion includes heating a composition including the aromatic polyol and a zinc-containing salt, so that the zinc-containing salt undergoes nucleophilic reaction and condensation reaction to form the zinc oxide component. A composition for preparing the dispersion is also disclosed.
    Type: Grant
    Filed: January 12, 2021
    Date of Patent: December 26, 2023
    Assignee: Far Eastern New Century Corporation
    Inventors: Li-Tzu Ting, Yu-Chun Wu, Wei-Che Hung
  • Patent number: 11844806
    Abstract: The present invention relates to a novel two-component system comprising acetylsalicylic acid (ASA) and which is particularly useful in providing an aqueous solution of ASA for immediate peroral administration.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: December 19, 2023
    Assignee: Asamedic AS
    Inventor: Carl Henrik Gorbitz
  • Patent number: 11820961
    Abstract: A fragrance composition comprising one or more musk or fragrance accords for use in reducing or inhibiting a subject's physiological reaction to stress. The composition can be incorporated into consumer products.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: November 21, 2023
    Assignee: TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Raphael K. L. Kang, Alba T. Cilia
  • Patent number: 11814464
    Abstract: Poly(amine-co-ester) polymers, methods of forming active agent-load polyplexes and particles therefrom, and methods of using them for delivery of nucleic acid agents with optimal uptake have been developed. Examples demonstrate critical molecular weights in combination with exposed carboxylic and/or hydroxyl groups, and methods of making. Typically, the compositions are less toxic, more efficient at drug delivery, or a combination thereof compared to a control other transfection reagents. In some embodiments, the compositions are suitable for in vivo delivery, and can be administered systemically to a subject to treat a disease or condition.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: November 14, 2023
    Assignee: YALE UNIVERSITY
    Inventors: W. Mark Saltzman, Yuhang Jiang
  • Patent number: 11812749
    Abstract: In an aspect, a method of making a composite comprises mixing titanium dioxide in a aqueous solution comprising an acid to form a titanium dioxide mixture; mixing an aniline monomer and an oxidizing agent with the titanium dioxide mixture to form a reaction mixture; and polymerizing the aniline monomer to form the composite comprising polyaniline and the titanium dioxide; wherein the titanium dioxide has an average particle size of 0.5 to 100 nm; and wherein the acid is free of a (C8+ alkyl) benzene sulfonic acid or a derivative thereof. In another aspect, a composite comprises a plurality of titanium dioxide having an average particle size of 0.5 to 100 nm; a polyaniline; at least one of hydrochloric acid or 2-acryamido-2-propanesulfonic acid or a derivative thereof; wherein the composite is free of a (C8+ alkyl) benzene sulfonic acid or a derivative thereof.
    Type: Grant
    Filed: May 14, 2021
    Date of Patent: November 14, 2023
    Assignee: THE UNIVERSITY OF MASSACHUSETTS
    Inventors: Sanjeev K. Manohar, Carl Lawton, Lekha Papammagari
  • Patent number: 11812747
    Abstract: A method of controlling or preventing pathogenic damage and/or pest damage in a plant propagation material, a plant, part of a plant and/or plant organ, comprising applying on the plant, part of the plant, plant organ, plant propagation material or a surrounding area thereof a phytoprotective agent comprising a protease.
    Type: Grant
    Filed: February 6, 2019
    Date of Patent: November 14, 2023
    Assignee: NOVOZYMES BIOAG A/S
    Inventors: Sharon Inch, Tine Hoff, Michael Frodyma, Michelle Maranta, Barbara Cherry
  • Patent number: 11801209
    Abstract: The various aspects presented herein relate to the cooling and flavor boosting compositions, and their use thereof.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: October 31, 2023
    Assignee: FIRMENICH SA
    Inventors: Muhammad A. Kizilbash, Qingbo Ouyang, Wenji Yuan, Jan Thomas Haines
  • Patent number: 11793753
    Abstract: Provided is a method of encapsulation, the method including: providing a first mixture, the first mixture including: a first carrier; and a first active ingredient; applying heat to the first mixture until the first mixture reaches a first temperature; providing a second mixture, the second mixture including: a second carrier; and a first emulsifying agent; applying heat to the second mixture until the second mixture reaches a second temperature; mixing the first mixture with the second mixture to obtain a third mixture, wherein: the mixing is performed at a third temperature; and the third temperature is lower than the first temperature; and cooling the third mixture until the third mixture reaches a fourth temperature, wherein: the second carrier is in solid state at the fourth temperature.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: October 24, 2023
    Assignee: Nulixir Inc.
    Inventor: Ehsan Moaseri
  • Patent number: 11786607
    Abstract: This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: October 17, 2023
    Assignee: ModernaTX, Inc.
    Inventors: Stephen Hoge, Joseph Schariter, Charles Bowerman, Michael H. Smith, Yan Xia
  • Patent number: 11779017
    Abstract: The present invention relates to an antimicrobial composition and more particularly to an antimicrobial composition at the pH of skin. The present invention provides an antimicrobial composition comprising: a. 0.5 to 20% by weight of a solvent comprising an alkyl glycol ether, b. 0.1 to 20% by weight of a carboxylic acid selected from an aromatic carboxylic acid having pKa greater than 4 or an aliphatic carboxylic acid having pKa greater than 4.5 or mixtures thereof c. 1 to 80% by weight of an anionic surfactant.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: October 10, 2023
    Assignee: CONOPCO, INC.
    Inventors: Sameer Keshav Barne, Maya Treesa Saji
  • Patent number: 11771771
    Abstract: Provided herein, in some aspects, are delivery vehicles comprising a ceramide and an agent to be delivered attached to the ceramide. In some embodiments, the ceramide does not comprise a fatty acid (i.e., is a sphingosine). In some embodiments, the ceramide comprises a fatty acid. In some embodiments, the ceramide is a glycoceramide. In some embodiments, the agent is attached to the ceramide covalently (e.g., via a linker). In some embodiments, the agent to be delivered is a therapeutic agent. The ceramide is able to deliver the agent to a cell or to a cellular compartment, as well as across the musical barrier. In some embodiments, agents delivered using the ceramide described herein exhibit longer half-life, compared to agents delivered alone. Methods of delivering a therapeutic agent to a subject for treating a disease using the ceramide delivery vehicle are also provided.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: October 3, 2023
    Assignee: Children's Medical Center Corporation
    Inventors: Wayne I. Lencer, Daniel J F Chinnapen, Richard I. Duclos
  • Patent number: 11773125
    Abstract: Methods of preparing steviol glycosides, including Rebaudioside D, Rebaudioside E, Rebaudioside M, Rebaudioside N and Rebaudioside O are provided herein. Sweetener and sweetened consumables containing Rebaudioside D, Rebaudioside E, Rebaudioside M, Rebaudioside N and Rebaudioside O are also provided herein.
    Type: Grant
    Filed: September 21, 2021
    Date of Patent: October 3, 2023
    Assignee: PURECIRCLE USA INC.
    Inventors: Avetik Markosyan, Siew Yin Chow, Khairul Nizam Bin Nawi
  • Patent number: 11759406
    Abstract: The present disclosure relates to a medical cement composition containing calcium silicate in an amount of less than 20 wt % of a total weight of the composition, with a lithium salt being added thereto. The medical cement composition of the present disclosure has a low compressive strength of 12 MPa or less, after being hardened, for easy removal, excellent stability in storage, and high bioactivity.
    Type: Grant
    Filed: September 20, 2021
    Date of Patent: September 19, 2023
    Assignee: Maruchi Co., Ltd.
    Inventor: Sung-Wook Jang
  • Patent number: 11744787
    Abstract: The invention relates to aroma preparations that contain (a) a compound of the formula (I) in which R1 represents a linear or branched, saturated or unsaturated hydrocarbon group with 1 to 4 carbon atoms, R2 represents hydrogen or a hydroxyl group and R3 represents hydrogen, a methyl or methoxy group, or an essential oil containing one or more compounds of the formula (I) and at least one menthol compound.
    Type: Grant
    Filed: May 14, 2016
    Date of Patent: September 5, 2023
    Assignee: Symrise AG
    Inventors: Sven Siegel, Arnold Machinek, Benoit Join
  • Patent number: 11744854
    Abstract: A composition which, in addition of the synergy of action of each of the composition-forming materials, can significantly enhance the efficaciousness of each material. Specifically, the composition comprises each of extract obtained from gotukora, amla, kotarahinbutsu, diosgenin and yamabushitake, and a divalent/trivalent iron salt as effective ingredients. The efficacy of each of the composition-forming materials is even more enhanced beyond expectation by containing the divalent/trivalent iron salt.
    Type: Grant
    Filed: November 11, 2020
    Date of Patent: September 5, 2023
    Inventors: Yoshishima Kijima, Mamdooh Helal Ghoneum
  • Patent number: 11737956
    Abstract: The present invention relates to a composition of an intracanal medication agent for medicating root canals for a predetermined period of time. According to one aspect of the invention, there is provided an intracanal medication composition based on a calcium hydroxide component, comprising: calcium hydroxide or a calcium hydroxide producing component as a powder component; and at least one of diethyl sulfoxide (DMSO), N-methyl-2-pyrrolidone (NMP) and diethylene glycol monoethyl ether (DEGEE) as a liquid component.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: August 29, 2023
    Inventor: Sung Wook Jang
  • Patent number: 11730753
    Abstract: The present invention relates to pharmaceutical compositions comprising trifluridine and tipiracil hydrochloride. More particularly, the present invention relates to a tablet composition comprising trifluridine, tipiracil hydrochloride and one or more pharmaceutically acceptable excipients and process for preparing such compositions.
    Type: Grant
    Filed: March 2, 2019
    Date of Patent: August 22, 2023
    Assignee: Natco Pharma Limited
    Inventors: Tripuraneni Rama Swamy Chowdary, Bhavanasi Krishna Murthy, Yedluri Siddhartha, Bhat Pavan, Nannapaneni Venkaiah Chowdary
  • Patent number: 11717498
    Abstract: The invention also relates to pharmaceutical compositions comprising highly pure amphetamine and amphetamine-class compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds, and to methods of manufacturing, delivering, and using the amphetamine compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: August 8, 2023
    Assignees: Pharmapotheca A, Inc., Chemapotheca, LLC
    Inventors: Karl Popp, Harold Meckler
  • Patent number: 11717536
    Abstract: The present invention relates to compositions and their use for oral care. In particular, the compositions and methods are for maintaining oral health and/or treating various oral conditions such as gingivitis. The present invention relates to methods and uses of stabilized amorphous calcium phosphate (ACP) and/or stabilized amorphous calcium fluoride phosphate (ACFP) in the preparation of a medicament for reducing pathogenic oral bacteria at an oral site in an individual; increasing commensal oral bacteria at an oral site in an individual; decreasing the proportion of pathogenic oral bacteria at an oral site in an individual; inhibiting oral dysbiosis; reducing gingival inflammation in an individual in need thereof; treating gingivitis in an individual in need thereof; and treating chronic gingivitis in an individual in need thereof.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: August 8, 2023
    Assignee: THE UNIVERSITY OF MELBOURNE
    Inventor: Eric Charles Reynolds