Patents Examined by Michael R Bloch
  • Patent number: 11071478
    Abstract: Systems, devices and methods are provided for inserting at least a portion of an in vivo analyte sensor, such as a dermal sensor, for sensing an analyte level in a bodily fluid of a subject. An applicator is positioned against a skin surface and a force is applied to the applicator causing at least a portion of a sharp and an in vivo analyte sensor to be positioned in the body of the subject. In particular, disclosed herein are embodiments of applicators designed to prevent premature sharp withdrawal and/or reduce the likelihood of improper sensor insertion. Also disclosed are embodiments of applicators including sharp modules having an angled sharp which can be configured to create an insertion path for a sensor.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: July 27, 2021
    Inventors: Vivek S. Rao, Louis G. Pace, Hyun Cho, Benjamin Jay Feldman, Yi Wang, Tuan Nguyen
  • Patent number: 11071481
    Abstract: Described herein is an apparatus to detect fetal acidosis during labor. This apparatus, which is noninvasive to the fetus, has a pH sensor and at least one fetal tissue detector. When the apparatus is inserted into the vaginal canal of a patient during labor, the pH reading determined by the pH sensor correlates to the pH of the fetus's blood. The fetal tissue detector may be a pulse oximeter, which may allow for a user to obtain the pulse rate reading of a surface contacted by the pH sensor. This pulse rate reading may be compared to an external reading of a pulse rate of the patient to confirm whether the pH sensor is contacting the fetus. During travel through the vaginal canal, the pH sensor may be protected by a protective sheath with an area of weakness to allow exposure of the pH sensor when the fetus is reached.
    Type: Grant
    Filed: January 22, 2020
    Date of Patent: July 27, 2021
    Assignee: Prenatal-Hope, Inc.
    Inventors: Tammy Dorsey, James Robert Balman
  • Patent number: 11040242
    Abstract: A breathing device includes a mouthpiece having a passage therein and a housing connected to the mouthpiece. The passage is configured to receive breaths including inhales and exhales. The breathing device further includes light emitters, a sensor and a controller. The light emitters have an operational status and non-operational status. The sensor is configured to sense pressure generated by the breaths and obtain pressure data associated therewith. The controller is configured to receive the pressure data and determine if breaths are exhales or inhales. The controller is further configured to transmit an inhale signal to the light emitters during an inhale to change their status in an inhale lighting predetermined sequence and timing. The controller is also configured to transmit an exhale signal to the lights emitters during an exhale to change their status in an exhale lighting predetermined sequence and timing.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: June 22, 2021
    Assignee: Breathe With B, Inc.
    Inventors: Eric Chesbrough, Richard M. Chesbrough
  • Patent number: 11040243
    Abstract: A breathing device including a housing portion and a mouthpiece portion. The housing portion has external and internal surfaces and a distal end portion and a proximal end portion. The mouthpiece portion has external and internal surfaces and includes a flared portion having a narrower distal end portion and extending to a wider proximal end portion, and the flared portion includes a depressed portion adjacent to the wider proximal end portion and configured to contact lips of a user.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: June 22, 2021
    Assignee: Breathe With B, Inc.
    Inventors: Eric Chesbrough, Richard M. Chesbrough, Gabriel Puerto
  • Patent number: 11033195
    Abstract: A method and system for extracting cardiac cycle parameters from a respiration signal is disclosed. The technique comprises an array of piezoelectric sensors planted on the chest. The chest membrane exhibits the characteristics of bulky attenuator with certain time delay. Contractions and expansions of the heart and lungs muscles model a mechanical load and produce a relative induced strain on the piezoelectric sheet which in turn causes the piezoelectric material to generate a corresponding conformal voltage signal that is mapped with the heart actions. The resultant voltage signal is therefore used to extract and model the corresponding heart parameters utilizing piezoelectric as well as signal processing theories. a direct relationship is established between the output voltage produced by the piezoelectric transducer under hold breathing and the respiration signal collected by the same transducer with respiration.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: June 15, 2021
    Assignee: United Arab Emirates University
    Inventors: Mahmoud F. Y. Al Ahmad, Areen Abdallah Romi Allataifeh
  • Patent number: 11026614
    Abstract: A pressure sensor apparatus includes: a plurality of pressure responsive chambers provided along a longitudinal dimension of the apparatus, and a pressure sensor device provided in each chamber which together provide a pressure profile in an anatomical cavity.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: June 8, 2021
    Assignee: Aukland UniServices Limited
    Inventors: Poul Michael Fonss Nielsen, Jennifer Ann Kruger, David Mortimer Budgett, Andrew James Taberner, John Daniel McCormick
  • Patent number: 11013433
    Abstract: Disclosed herein are systems and methods for non-invasively monitoring blood glucose levels with a level of accuracy that is high enough to replace invasive methods such as finger prick devices and others. In some examples, glucose values are determined using a patient's electrocardiogram (ECG) signals. Additionally, glucose values may additionally be determined using an impedance spectroscopy based method and then combined with glucose values determined using an ECG waveform to output a blood glucose value.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: May 25, 2021
    Assignee: Anexa Labs LLC
    Inventor: Alexey Reykhert
  • Patent number: 10987493
    Abstract: Provided is a guide wire having a novel structure, with which it is possible to improve production efficiency and to effectively prevent large irregularities from forming on an outer circumferential surface of a core wire. Further provided is a guide wire having a novel structure, with which it is possible to more meticulously set bending rigidity to a distal end portion thereof. In a guide wire having a coil externally mounted about a distal end portion of a core wire, a proximal end portion of the coil is integrally joined to the core wire during formation of the coil. Furthermore, in a guide wire having a coil externally mounted about a distal end portion of a core wire, a cross-sectional shape of a wire that constitutes the coil varies in a lengthwise direction of the coil.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: April 27, 2021
    Inventors: Yoshihiko Sano, Katsuhiro Hiejima
  • Patent number: 10987485
    Abstract: The invention relates to an insertion device (110) for inserting an analyte sensor (114) into a body tissue. The insertion device (110) comprises an insertion needle holder (120) and a drive mechanism (124) for driving the insertion needle holder (120) in a longitudinal direction (126). The drive mechanism (124) comprises at least one actuator (132) for actuating the drive mechanism (124). The drive mechanism (124) comprises a rotor (142) adapted to transform an actuation motion of the actuator (132) into a motion of the insertion needle holder (120) in the longitudinal direction (126). The insertion device (110) further comprises at least one safety lock (164). The safety lock (164), in a locked position, is adapted to at least partially block a rotation of the rotor (142). In an unlocked position, the safety lock (164) is adapted to permit the rotation of the rotor (142).
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: April 27, 2021
    Inventors: Stephan-Michael Frey, Oliver Kube, Andrea Rittinghaus
  • Patent number: 10980431
    Abstract: A monitoring device is included in a medical system to implement a method for prediction of a rapid symptomatic drop in a subject's blood pressure, e.g. during a medical treatment such as dialysis. To this aim, a pulse shape parameter (pPS) with respect to a pulse generator of the subject is registered by means of a pressure sensor arranged in an extracorporeal blood flow circuit coupled to a cardiovascular system of the subject (P). The pressure sensor is configured to detect pressure variations in blood vessels of the subject (P). It is investigated, during measurement period, whether or not one or more of the pulse shape parameters fulfil a decision criterion. An output signal (a) is generated if the decision criterion is found to be fulfilled, to indicate a predicted rapid symptomatic blood pressure decrease in the subject (P).
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: April 20, 2021
    Assignee: GAMBRO LUNDIA AB
    Inventors: Bo Olde, Kristian Solem
  • Patent number: 10932674
    Abstract: Devices and methods for monitoring physiologic parameters are described herein which may utilize a non-invasive respiratory monitor to detect minor variations in expiratory airflow pressure known as cardiogenic oscillations which are generated by changes in the pulmonary blood volume that correspond with the cardiac cycle. These cardiogenic oscillations are a direct indicator of cardiac function and may be used to correlate various physiologic parameters such as stroke volume, pulmonary artery pressure, etc.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: March 2, 2021
    Assignee: Respirix, Inc.
    Inventors: Evan S. Luxon, Daniel R. Burnett, Stephen Boyd
  • Patent number: 10905342
    Abstract: Methods, associated algorithms, and systems for determining cardiac and/or cardiovascular performance from three measurements on a subject are presented, where two of the measurements are provided by plethysmographs and one measurement is provided by an electrocardiogram. The two plethysmographs are placed different distances from the subject's heart. Certain embodiments use the three measurements to calculate intermediate variables of a left ventricular ejection time and a pre-ejection period.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: February 2, 2021
    Assignee: Cardiac Profiles, Inc.
    Inventors: Bernhard B. Sterling, Andrew R. Lawrence, Gregory I. Voss, James M. Perry, Rankin A. Clinton, III
  • Patent number: 10898120
    Abstract: Provided is a system for monitoring a state of a user. The system includes a chair including a backrest and a seat plate, at least one flexible tactile sensor positioned in the back plate or seat plate and configured to sense a motion of a user who sits on the chair. The system further includes a monitoring apparatus configured to monitor the state of the user based on the sensed value received from at least one flexible tactile sensor.
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: January 26, 2021
    Inventors: Kunnyun Kim, Kwang Bum Park, Won Hyo Kim, Yeon Hwa Kwak
  • Patent number: 10898116
    Abstract: Methods and systems for manufacturing a transdermal sampling and analysis device for non-invasively and transdermally obtaining biological samples from a subject and determining levels of analytes of the obtained biological samples are provided. A method of manufacturing the device may improve performance and includes forming channel structures on the lid of the device, thereby making the spacer/channel support structures physically independent and separable from the sensing electrode. Other methods of manufacturing the device may improve performance and include forming at least one of the electrodes on each of the base and the lid, and forming a recessed second spacer layer over the channel support structures, thereby separating the channel support structures and the electrode on the lid to allow a larger area of the electrode to be exposed to the biological sample.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 26, 2021
    Assignee: Cambridge Medical Technologies LLC
    Inventors: Joseph J Vidalis, Joseph A Marcanio, John Frederick Currie, Helena Woodvine Snyder, Vikas Bhatia
  • Patent number: 10898085
    Abstract: A pressure distribution profile of a subject lying on a mat is used to derive a measure of pulse wave velocity. Beat locations are identified where beat pressure signals are identified, and pulse timing information is obtained from the beat locations. By determining a subject posture, the beat locations are mapped to anatomical body locations and arterial path length information is obtained for the anatomical body locations. A pulse wave velocity is then estimated from the pulse timing information and arterial path lengths. This method enables measuring the pulse wave velocity during sleep in a comfortable, easy and unconstrained manner. This is accomplished by analyzing signals from a pressure sensitive surface for example on top of a bed mattress or by embedding a pressure sensitive layer in the mattress.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: January 26, 2021
    Inventors: Koen Theo Johan De Groot, Mustafa Ghassan Radha, Jozef Hubertus Gelissen, Reinder Haakma
  • Patent number: 10898160
    Abstract: The present invention relates to a system (100) and method (800) capable of indirectly monitoring respiratory and cardiac variables. A decomposition technique on time-series of features extracted from the chest audio signal ?(t) is proposed. The proposed monitoring system (100) may acquire the acoustic signal on the chest of a subject (140) by means of a wearable transducer (150). The proposed system may estimate a number of physiological variables such as flow estimates, respiration rate, inspiration and expiration markers and cardiac related variables. Cough and apnea detection, adventitious sound recognition, activities performed, and information about energy estimation and the status of a monitored subject can be derived as well.
    Type: Grant
    Filed: November 27, 2015
    Date of Patent: January 26, 2021
    Inventors: Gabriele Spina, Albertus Cornelis Den Brinker
  • Patent number: 10898123
    Abstract: Disclosed is system for assessing a motor function, the system including a sensor configured to acquire human body exercise information including a joint position, a joint orientation, a grasp state, or a grasp force, a processor configured to extract an exercise feature for analyzing a human body motion time and human body motion information based on the acquired human body exercise information, analyze at least one target motion for assessment based on a set assessment condition using the extracted exercise feature, classify an assessment factor of the at least one target motion for assessment as a success or a failure, and determine a final assessment score of the at least one target motion for assessment based on the classified assessment factor, and a display configured to display the final assessment score.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: January 26, 2021
    Inventors: Jong Hyun Kim, Seunghee Lee, Sang Hyuk Son, Paul Otten
  • Patent number: 10898141
    Abstract: A system and method for evaluating the respiratory health of a patient and indicating and characterizing respiratory stress includes a sensor in operative communication with a patient for generating at least one biological signal, having a waveform curve in the time domain. The biological signal is processed and a waveform curve is computed, reflective of the respiration rate of the patient. A correlation is then determined between the biological signal waveform curve and respiration rate waveform curve and a respective correlation coefficient is determined. Frequency analysis is performed on the biological signal and a determination is made of a respiration metric reflective of the ratio of spectral components associated with the respiration component of the biological signal in relation to the total spectral components for the biological signal. The correlation coefficient and the respiration metric are combined to form a respiratory stress metric for displaying to a user.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: January 26, 2021
    Assignee: Intelomed, Inc.
    Inventor: Anne Brumfield
  • Patent number: 10856752
    Abstract: The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. a TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) a processing system, typically worn on the patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors.
    Type: Grant
    Filed: December 27, 2011
    Date of Patent: December 8, 2020
    Inventors: Matt Banet, Isaac Henry, Donald Bernstein
  • Patent number: 10842395
    Abstract: Apparatus for monitoring arterial pulse waves includes at least one separator ring receivable on at least one digit of a limb effective to tether a feed tube supplying a measuring device to a digit. Each separator ring is of a compliant material, of a non-interrupted tubular configuration, designed to avoid interference of blood supply to or from the digit to which it is applied, and of sufficient resilience and thickness to enable it to distance each adjacent digit from a digit mounted tubular socket probe so as to prevent contact between the tubular socket probe and adjacent digits, without interference to blood circulation, irrespective of the thickness of the digit on which the separator ring is received.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: November 24, 2020
    Assignee: Itamar Medical Ltd.
    Inventors: Robert P. Schnall, Jacob Sheffy