Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.

Abstract: Disclosed are an ultrasound diagnostic apparatus and an ultrasound image producing method capable of producing a spatial compound image with reduced artifacts. Reception data of frame images is repeatedly acquired in a data acquisition cycle of four frames such that, of three frame images for use in producing a spatial compound image, the angle difference in steering angle between two frames for which the acquisition of reception data is most temporally separated is smaller than a maximum value among the angle differences in steering angle between two frame images among three frame images having different steering angles, and each time reception data of two frame images or reception data of another two frame images is acquired, three frame images sequentially produced based on reception data for three frames sequentially acquired hitherto are synthesized to produce a spatial compound image.

Abstract: A system and method for MR imaging is disclosed. The method causes an RF coil assembly and plurality of gradient coils to apply a fast spin echo (FSE) pulse sequence comprising a preparation segment and a plurality of refocusing segments. The FSE pulse sequence generates a pair of echoes is generated in each of the plurality of refocusing segments that comprises a first echo generated by magnetization pathways having an even number of phase inversions and a second echo generated by magnetization pathways having an even number of phase inversions. MR signals are acquired from the first echo and the second echo and an image of at least a portion of a subject of interest is reconstructed from the acquired MR signals.

Abstract: A method and a system for producing images of a subject, such as the heart of a human being. The method may comprise acquiring ultrasound images of the subject with a catheter comprising a position sensor. The method may also comprise capturing a plurality of 4D surface registration points in the acquired ultrasound images corresponding to points on the subject. The method may also comprise registering, in space and time, a high-resolution 4D model of the subject with the plurality of 4D surface registration points. The method may also comprise displaying high resolution, real-time images of the subject during a medical procedure based on the registration of the high resolution 4D model to the 4D surface registration points. Embodiments of the present invention are especially useful in left atrium ablation procedures.

Abstract: An ultrasound system comprises a probe for acquiring ultrasound data associated with a patient and a microphone detecting audio. The system further comprises a processor module and a memory. The processor module is configured to receive the ultrasound data from the probe and processes the ultrasound data to form an image file. The processor module is further configured to receive the audio from the microphone and forms a voice recording file based on the received audio. The memory stores the image file and the voice recording file, and the processor module automatically associates the image file and the voice recording file with each other.

Abstract: A method is disclosed for determining a position-dependent attenuation map of at least one surface coil of a combined magnetic resonance/PET apparatus. In an embodiment, the method includes acquiring magnetic resonance image data by way of the at least one surface coil during a magnetic resonance/PET examination of a patient; reconstructing the position of the at least one surface coil on the basis of the acquired magnetic resonance image data; and determining the position-dependent attenuation map of the at least one surface coil on the basis of the reconstructed position of the at least one surface coil. A magnetic resonance/PET apparatus and a computer program product, embodied to perform the method, are also disclosed.

Abstract: Systems and methods are disclosed that improve conventional tracking and modeling methods for determining three-dimensional bone motion from sequences of radiographic images. These enhancements significantly improve the speed, reliability and accuracy for bone motion tracking. Techniques used in various embodiments include multi-bone hierarchical techniques, time coherent approaches, simultaneous optimization of the entire motion sequence and improved initial estimates of bone motion paths.

Abstract: Some embodiments provide a method of providing ultrasound energy having a stable power output. The method can comprise providing ultrasound energy from a ultrasound transducer; determining a power level threshold of the ultrasound energy; monitoring a power level of the ultrasound energy over time of the ultrasound energy; communicating a power level to a controller; adjusting the frequency of the ultrasound energy upon a change in the power level; and maintaining the power level threshold of the ultrasound energy.

Abstract: A method and related system for providing therapy to a treatment site, such as stenosis or other vasculature disease, at one or more locations of a subject, such as the vasculature. The method includes: advancing an ultrasound catheter to or in proximity to the subject's treatment site; infusing microbubbles into or proximal to the treatment site; and delivering ultrasonic energy from the ultrasound catheter. The ultrasonic energy may be adapted for: imaging the treatment site, translating the microbubbles into or in the vicinity of the treatment site and/or rupturing the microbubbles.

Abstract: An ultrasound endoscope according to the invention includes: an ultrasound transducer that transmits/receives ultrasound; a housing in which the ultrasound transducer is fixed via an adhesive, and which houses the ultrasound transducer; an inner peripheral face forming a rectangular first opening portion for exposing the ultrasound transducer, the first opening portion being formed in the housing; an acoustic lens forming a part from an upper face to at least a side face of the ultrasound transducer; and a chamfered portion provided at a side face of the acoustic lens, an adhesive outlet port for the adhesive to flow to an outside from the first opening portion being formed between the chamfered portion and the inner peripheral face.

Abstract: The present application includes a position tracking system for tracking the location of surgical objects within the surgical field, a neuromonitoring system for detecting the existence of (and optionally the distance and/or direction to) neural structures during a surgical procedure, and a processing system communicatively linked to both the position tracking system and the neuromonitoring system.

Abstract: A soundhead of a treatment device is provided that enables a volume of tissue located beneath the soundhead to simultaneously receive ultrasound and light stimulation. According to one embodiment, the soundhead includes an ultrasound transducer, a light source, and a faceplate extending across a face of the transducer for providing a tissue contacting and ultrasound energy coupling surface of the soundhead. The faceplate is transparent or translucent to the light generated by the light source. Alternate embodiments including externally mounted light sources are also disclosed.

Abstract: Systems and methods for evaluating prospective treatments for progressive brain disorders like Alzheimer's disease and the progressive effects of aging involve the use of an imaging device communicatively coupled to a computing device. The imaging device may takes a plurality of brain imaging measurements from each of a plurality of human subjects who are divided into a treated group and an untreated group based on various subject data including whether the subjects carry certain alleles of genes known to increase the risk of developing the brain disorder at issue. The computing device receives the brain imaging measurements from the imaging device and applies an advanced processing method that permits enhanced computational efficiency when calculating rates of change for the two groups and determining whether any calculated difference between the rates is statistically significant.

Abstract: A vascular access monitoring device for monitoring characteristics of a skin piercing vascular access device comprising: an acoustic sensor operable to detect an acoustic emission created by flow through said vascular access device and produce an electrical signal indicative of said emission; electronics processing means for processing and monitoring said electrical signal, and to determine, by identifying a change of characteristic of said signal, the possibility that the vascular access device has become dislodged from its normal working position.

Abstract: A method and system for estimating arterial compliance and resistance based on medical image data and pressure measurements is disclosed. An arterial inflow estimate over a plurality of time points is determined based on medical image data of a patient. An arterial pressure measurement of the patient is received. At least one cardiac cycle of the arterial pressure measurement is synchronized with at least one cardiac cycle of the arterial inflow measurement. Arterial compliance and resistance of the patient is estimated based on the arterial inflow estimate and the synchronized arterial pressure measurement.

Abstract: Methods and systems for sensing properties of an object or entity utilize non-resistive contact sensors alone or in combination with other sensors. The sensor data is utilized for detecting and visualizing properties of one or more biological or non-biological objects or entities.

Abstract: An ultrasonic probe includes a substrate, a diaphragm, a thin-film piezoelectric element, a communication passage, and an air hole. The substrate has first and second cavities thereon. The diaphragm is configured at the first cavity. The thin-film piezoelectric element is configured to the diaphragms. The communicating passage is configured in the substrate and extending from the first cavity to the second cavity. The air hole extends between the communicating passage to an outside of the substrate.

Abstract: Nuclear medicine (NM) imaging system including first and second NM cameras having camera surfaces that are configured to face each other while imaging patient tissue therebetween. The NM imaging system also includes an immobilization plate that is configured to be positioned between the first and second NM cameras and extend parallel to the camera surface of the first NM camera. The immobilization plate is movable to and from the camera surface of the first NM camera to compress the patient tissue, and the second NM camera is movable to and from the immobilization plate. The second NM camera is oriented with respect to a roll axis that extends parallel to the immobilization plate. The second NM camera is rotatable about the roll axis while the immobilization plate and the first NM camera have fixed positions with respect to each other with the patient tissue therebetween.

Abstract: In an ultrasonic diagnostic apparatus according to an embodiment, a direction determining unit determines a moving direction of an ultrasonic probe. A scanning control unit controls a transmitting and receiving unit so as to repeatedly perform first scanning for acquiring first image data by transmitting and receiving an ultrasonic signal in a first direction and second scanning for acquiring second image data by transmitting and receiving the ultrasonic signal in a second direction inclined toward the moving direction with respect to the first direction. An image superimposing unit generates panoramic image data by superimposing a plurality of pieces of first image data acquired through the first scanning. A display control unit displays the second image data together with the panoramic image data or the first image data on a display unit during scanning.

Abstract: An apparatus is utilized for accessing the lumen of a vessel. The apparatus includes a main body and a disposable cartridge. The main body includes a imaging device attachment, wherein the imaging device attachment is utilized to secure an image capturing instrument to the main body; a cartridge carrier coupled to the imaging device attachment, wherein the cartridge carrier is adjustable to achieve a target insertion depth; and a first motor coupled to the cartridge carrier, wherein the first motor adjust the cartridge carrier to achieve the target insertion depth. The disposable cartridge is attached to the cartridge carrier and houses a sheath, needle, or guidewire to be inserted into the vessel to the target insertion depth.