Abstract: A cancer invasiveness diagnosis system includes an endoscope; a microtomography probe which is introduced into a body cavity together with the endoscope, the microtomography probe emitting a low-coherence light on a target tissue in which a target tumor is present to obtain an optical interference signal; a determination portion which is configured to obtain a tomography image of the target tissue including the target tumor and a blood flow velocity information in a blood vessel in the tomography image based on the optical interference signal, wherein the determination portion is configured to determine the cancer invasiveness of the target tumor based on the tomography image and the blood flow velocity information.

Abstract: An ultrasound imaging system includes an interventional medical device having a first tracking element that generates tip location data based on an EM locator field. An ultrasound probe has an ultrasound transducer mechanism and a second tracking element. The ultrasound transducer mechanism has an active ultrasound transducer array that generates two-dimensional ultrasound slice data at any of a plurality of discrete imaging locations within a three-dimensional imaging volume. The second tracking element generates probe location data based on the EM locator field. A processor circuit is configured to execute program instructions to generate an ultrasound image for display, and is configured to generate a positioning signal based on the tip location data and the probe location data to dynamically position the active ultrasound transducer array so that the two-dimensional ultrasound slice data includes the distal tip of the interventional medical device.

Abstract: In a photoacoustic image generation apparatus for obtaining a photoacoustic signal by emitting light toward a subject from a light source and detecting photoacoustic waves emitted from the subject having received the light and imaging the subject based on the photoacoustic signal, there are provided: means for removing a signal showing a component appearing discontinuously in the subject from photoacoustic signals relevant to a plurality of cross sections of the subject that have been generated by changing an angle between an emission direction of the light and a surface of the subject; and means for constructing a three-dimensional image of the subject from photoacoustic signals showing the plurality of cross sections after the removal processing.

Abstract: Aspects of technology described herein relate to guiding collection of ultrasound data collection using motion and/or orientation data. A directional indicator corresponding to an instruction for moving an ultrasound imaging device relative to a subject may be displayed in an augmented reality display. The direction of the directional indicator in the augmented reality display may be independent of an orientation of the ultrasound imaging device. The augmented reality display may include video captured by a camera that depicts the ultrasound imaging device and a fiducial marker on the ultrasound imaging device. The direction of the directional indicator may be based on the pose of the camera relative to the fiducial marker and the rotation and/or tilt of the ultrasound imaging device relative to the axis of gravity. The direction of the directional indicator may also be based on the pose of the camera relative to the subject.

Abstract: Methods and systems for alignment of a subject for medical imaging are disclosed, and involve providing a reference image of an anatomical region of the subject, the anatomical region comprising a target tissue, processing the reference image to generate an alignment reference image, displaying the alignment reference image concurrently with real-time video of the anatomical region, and aligning the real-time video with the alignment reference image to overlay the real-time video with the alignment reference image. Following such alignment, the subject may be imaged using, for example, fluorescence imaging, wherein the fluorescence imaging may be performed by an image acquisition assembly aligned in accordance with the alignment.

Abstract: Method and system form a correlated view of human or other animal anatomy using at least one transparent display screen associated with an electronic mobile device. The view relates an optical view with other electromagnetic spectrum images with a non-optical electromagnetic image of selected portions of human or other animal anatomy. At least three visible position markers associate with selected positions of a predetermined portion of human or other animal anatomy. The disclosure forms a correlated view of the predetermined portion of human or other animal anatomy by relating said at least one non-optical electromagnetic image of the at least three visible position markers with a visual image of said at least three visible position markers. The view correlates the size and dimensions of the optical view and non-optical electromagnetic image of the predetermined portion of human or other animal anatomy.

Abstract: A system for individualized treatment of a tissue condition with acoustic pressure shocks includes personalized determination and automatic adjustment of a shock wave treatment regimen or shock wave dosage to be administered for personalized treatment based on factors such as a patient's comorbidities, state of the tissue condition, individual physical characteristics and lifestyle parameters.

Abstract: An ultrasonic diagnostic system comprises: a first transceiver for performing transmission/reception of first ultrasound for detecting shear waves generated in a subject by mechanical vibration; a second transceiver for performing transmission/reception of second ultrasound to/from the subject; a computing section for calculating a value of a parameter affecting a frequency of the first ultrasound to be transmitted from the first transceiver based on echo signals obtained by transmission/reception of the second ultrasound; an identifying section for identifying one first transceiver from among a plurality of kinds of first transceivers each having a different frequency of said first ultrasound based on the value of said parameter; and a display device for displaying the first transceiver identified by the identifying section.

Abstract: A system includes an energy source configured to generate therapeutic energy, a treatment probe, an ultrasound imaging device configured to generate ultrasound images, a second tracking sensor configured to track a location of the ultrasound imaging device, and a tracking system configured to receive location information from the first and second tracking sensors and to overlay the ultrasound images with a graphical representation of the treatment probe on a display based on the location information. The treatment probe includes an antenna configured to treat tissue with the therapeutic energy and a first tracking sensor integrated in the antenna and configured to track a location of a distal tip of the antenna.

Abstract: A system for presenting multiple parallel slices comprises a display for displaying ultrasound data comprising 3D Doppler data over time. A user interface defines a proximal plane and a distal plane within the ultrasound data that are parallel to one another. The proximal and distal planes define a region of interest (ROI). A signal processor automatically extracts at least two slices based on the ultrasound data within the ROI. The at least two slices are parallel with respect to each other and are displayed on the display.

Abstract: The invention relates to a new method, as well as diagnosis. A non-invasive marker, systems and equipment are also included.

Abstract: Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.

Abstract: Apparatus and method for imaging a patient in an MRI system. This includes a frame, and at least one assembly that includes a patient-interface positioner connected to a reference position on the frame, a first lockable joint on the positioner; and a patient interface connected to a patient-proximal end of the positioner by a second joint, wherein the first patient-interface is moveably positioned to a selected pitch angle, a selected yaw angle, and a selected one of a plurality of distances relative to the reference position on the frame. The first lockable joint is configured to be tightened to yieldably hold the first patient-interface at the selected pitch and yaw angles, and at the selected one of the plurality of distances, relative to the reference position. Optionally a second substantially similar patient-interface and assembly are provided. The earpiece(s) optionally include audio transducer(s) and/or RF coil(s).

Abstract: A syringe having an energy source disposed therein is disclosed. The syringe is capable of both the delivery and/or aspiration of materials as well as the delivery of an effective amount of various types of energy to a target to produce a desired result. A method utilizing the syringe to administer materials and to deliver energy to the material is also disclosed.

Abstract: A tracking system and a tracking method using the same are disclosed. The tracking system includes a marker, a camera unit, a first inertial measuring unit, a second inertial measuring unit and a tracking processing unit. The marker is fixed on the measurement object, and the camera unit outputs a marker image by photographing the marker. The first inertial measuring unit is fixed on the camera unit, and measures and outputs first inertia comprising first accelerated velocity and first angular velocity. The second inertial measuring unit is fixed to one of the measurement object and the marker, and measures and outputs second inertia comprising second accelerated velocity and second angular velocity. The tracking processing unit primarily extracts the position and the posture of the measurement object using the marker image, and secondarily extracts the position and the posture of the measurement object using the first and second inertias.

Abstract: An apparatus is disclosed for assisting in providing a diagnosis of a medical condition of a mammal brain. The apparatus includes an input facility, a conversion facility, and an output device. In an operational mode the input facility receives a first value and a second value. The input facility further receives first reference data indicative for a cumulative distribution of the first value for said portion in a reference population and second reference data indicative for a cumulative, distribution of the second value for the corresponding portion in the reference, population. The conversion facility determines a third value indicating the cumulative probability of the first value and a fourth value indicating the cumulative probability of the second value. The output device generates a signal indicating a substantially monotonically increasing function of a difference between the third and the fourth value.

Abstract: The disclosure herein provides methods, systems, and devices for virtually staining biological tissue for enhanced visualization without use of an actual dye or tag by detecting how each pixel of an unstained tissue image changes in waveform after staining with a certain dye(s) and/or tag(s) or other transformation under a certain electromagnetic radiation source, developing a virtual staining transform based on such detection, and applying such virtual staining transform to an unstained biological tissue to virtually stain the tissue.

Abstract: In a photoacoustic image generation apparatus for generating a photoacoustic image of a subject including an interventional instrument for each scanning plane, there are provided: means for generating a reflected acoustic wave image of the subject for each scanning plane; means for detecting a change in a photoacoustic image on an observation scanning plane, which is generated as an image, from a plurality of photoacoustic images regarding the observation scanning plane; means for detecting a change in a reflected acoustic wave image on the observation scanning plane from a plurality of reflected acoustic wave images regarding the observation scanning plane; determination means for determining whether or not a distal end of the interventional instrument is present on the observation scanning plane based on the change in the photoacoustic image and the change in the reflected acoustic wave image; and notification means for sending notification of a result of the determination.

Abstract: Systems and methods for identifying a location and/or an orientation of an electromagnetic (EM) sensor navigated within an EM volume are provided. Calculated EM field strengths at each gridpoint of a second set of gridpoints of the EM volume are retrieved from a memory. An EM field is generated by way of an antenna assembly. A measured EM field strength is received from the EM sensor. A first gridpoint among a first set of gridpoints of the EM volume is identified based on the measured EM field strength and a high density (HD) map. The location and/or the orientation of the EM sensor is identified based on the HD map, using the first gridpoint as an initial condition, with the second set of gridpoints also including the first set of gridpoints.

Abstract: Aspects of the present disclosure relate to magnetic resonance thermometry. In one embodiment, a method includes acquiring undersampled magnetic resonance data associated with an area of interest of a subject receiving focused ultrasound treatment, and reconstructing images corresponding to the area of interest based on the acquired magnetic resonance data, where the reconstructing uses Kalman filtering.