Abstract: The present disclosure is drawn to pharmaceutical compositions and oral dosage capsules containing testosterone undecanoate, as well as related methods. The capsule includes a capsule shell and a capsule fill. The capsule fill can include a solubilizer and about 14 wt % to about 35 wt % testosterone undecanoate based on the total capsule fill. The oral dosage capsule is such that when a single oral administration to a male subject of one or more capsules with a total testosterone undecanoate daily dose of about 350 mg to about 650 mg it provides a ratio of serum testosterone Cmax to serum testosterone Cave of about 2.7 or less. In yet another embodiment, a method for providing a serum concentration of testosterone within a target serum testosterone concentration Cave range for a male subject is provided.

Abstract: The present disclosure is drawn to pharmaceutical compositions and oral dosage capsules containing testosterone undecanoate, as well as related methods. The capsule includes a capsule shell and a capsule fill. The capsule fill can include a solubilizer and about 14 wt % to about 35 wt % testosterone undecanoate based on the total capsule fill. The oral dosage capsule is such that when a single oral administration to a male subject of one or more capsules with a total testosterone undecanoate daily dose of about 350 mg to about 650 mg it provides a ratio of serum testosterone Cmax to serum testosterone Cave of about 2.7 or less. In yet another embodiment, a method for providing a serum concentration of testosterone within a target serum testosterone concentration Cave range for a male subject is provided.

Abstract: A powder formulation, or pharmaceutical composition comprising or consisting of particles of an antimuscarinic agent, said particles being obtainable by supercritical anti-solvent (SAS) precipitation and having a D50 of 4 ?m or less and a D90 of 10 ?m or less. Methods of forming the formulation and composition are also disclosed, as are uses of the composition.

Abstract: The present invention relates to 1-amino-1-cyclopropanecarboxylic acid hydrochloride salt formulations and methods of their use.

Abstract: The present disclosure describes a formulation including a nanoparticle including a polymer-associated strobilurin compound with an average diameter of between about 1 nm and about 500 nm; wherein the polymer is a polyelectrolyte, and a dispersant or a wetting agent. The disclosure describes various formulations and formulating agents that can be included in the formulations. Additionally, the disclosures describes application to various plants and fungi as well as advantages of the disclosed formulations.

Abstract: The present invention provides a method for increasing the artemisinin yield in Artemisia annua L. using ?-ocimene and belongs to the technical field of artemisinin production and extraction. The method treats Artemisia annua L. plants by ?-ocimene for 1-3 d. The method selects Artemisia annua L. grown for at least 21 d as the object to be treated by ?-ocimene. The method is very simple and can achieve multiple harvest within one year; meanwhile, it can significantly increase the artemisinin yield in Artemisia annua L. plant and largely increase the artemisinin yield, thereby achieving an industrialized operation.

Abstract: The present disclosure is directed to floating gastroretentive dosage forms with prolonged gastric residence time. The disclosure also provides rapidly expanding sustained release or combined immediate release and sustained release formulations comprising drugs that require targeted release in the proximal gastrointestinal tract for maximum therapeutic benefit. The rapidly expanding floating gastroretentive dosage forms comprise a permeable elastic membrane providing desired characteristics for drug release and mechanical strength to maintain tablet integrity.

Abstract: The invention provides a method of inducing satiety in a subject comprising a step of orally administering a composition comprising an effective amount of a first agent capable of inducing satiety and of a second agent capable of augmenting the satiety-inducing effect of the first agent. Also disclosed are compositions for carrying out the method, and a body weight management system comprising such compositions in combination with a device configured for the collection, storage and/or display of information relating to a subject's response to a predefined therapeutic regimen of orally administering the composition.

Abstract: An herbicidal combination including a photosystem II inhibitor, an ALS inhibitor, and a chlorophyll and heme biosynthesis inhibitor, a composition comprising the combination, and methods of using these combinations are described.

Abstract: The present disclosure is drawn to pharmaceutical compositions and oral dosage capsules containing testosterone undecanoate, as well as related methods. The capsule includes a capsule shell and a capsule fill. The capsule fill can include a solubilizer and about 14 wt % to about 35 wt % testosterone undecanoate based on the total capsule fill. The oral dosage capsule is such that when a single oral administration to a male subject of one or more capsules with a total testosterone undecanoate daily dose of about 350 mg to about 650 mg it provides a ratio of serum testosterone Cmax to serum testosterone Cave of about 2.7 or less. In yet another embodiment, a method for providing a serum concentration of testosterone within a target serum testosterone concentration Cave range for a male subject is provided.

Abstract: Disclosed are N-(1,3,4-oxadiazole-2-yl)aryl carboxamides of formula (I) or the salts (I) thereof as well as the use thereof as herbicides.

Abstract: The present invention relates to methods of treating subjects having heart failure with preserved ejection fraction (HFpEF) with a sustained-delivery formulation of cardiotonic 5-(pyridinyl)-2(1H)-pyridinone compounds.

Abstract: The invention relates to an agrochemical composition comprising propylene carbonate, up to 10 wt % of water, and compounds I their salts, tautomers, or enantiomers; wherein the variables are as defined in the description. The invention also relates to a process for the preparation of the composition, comprising mixing the propylene carbonate, compounds I, and optionally an acid and/or cyclohexanone. It also relates to a method for controlling pests, which method comprises the application of the composition, or a dilution thereof, to plants, plant propagation material, or the locus of growth of the plants; the pests or their food supply, habitat or breeding grounds. Other objects are the use of cyclohexanone and/or an acid, in particular acetic acid, for stabilizing compositions comprising compounds I; composition for stabilizing water-soluble pesticides as defined in any of claims 1 to 9, comprising 1 to 50 wt % of propylene carbonate, 0.

Abstract: Method for making a Cannabinoid molecule bath bomb by first etching the surface of at least one of ?9 Tetrahydrocannabinol molecule and Cannabidiol molecule. The etched Cannabinoid molecule is then combined with Sodium Bicarbonate, Citric acid, Magnesium Chloride, and a viscous binder. Once the ingredients have been combined the resulting mixture is dried to form a Cannabinoid molecule bath bomb.

Abstract: This disclosure relates to picolinamides of Formula I and their use as fungicides.

Abstract: Cosmetic lipophilic composition comprising less than 20% by weight of an aqueous component and an oily component characterized in that the oily component comprises at least one ester selected from neopentylglycol dipelargonate, glycerol tripelargonate, pentaerythritol tetrapelargonate or mixtures thereof.

Abstract: The present application provides an application of quercetin in a plant senescence accelerator, which belongs to the field of plant senescence accelerators and its application, and can prepare a plant senescence accelerator by using quercetin and apply the accelerator in practical production to accelerate the senescence process of plant particularly crop leaves. The quercetin plant senescence accelerator is prepared by mixing a quercetin mother solution with a 1/2 MS solution of 2-(N-morpholino)ethanesulfonic. In the present application, by adopting directly spraying method, the senescence process of plant leaves can be accelerated, and will not cause additional adverse reactions to plants.

Abstract: Provided is a composition for preventing hair loss or promoting hair development, comprising, as an active ingredient, irone or a pharmaceutically acceptable salt thereof. More specifically, provided is a pharmaceutical composition, a quasi-drug composition, a cosmetic composition, or a health functional food composition, for preventing hair loss, treating hair loss, promoting hair development, or promoting hair growth, the composition comprising irone or a salt thereof as an active ingredient. The composition not only contains, as an active ingredient, a natural compound having no adverse effects even when administered for a long period of time with respect to hair loss, a chronic disease, but also exhibits excellent and stable efficacy in hair development and hair growth, which allows the composition to be usefully used as an agent for preventing or treating hair loss, or a pharmaceutical, quasi-drug, cosmetic, or health functional food composition for promoting hair development or hair growth.

Abstract: The present disclosure relates to a dissolvable thin oral tape, film or strip or segment thereof composition or device, including a film former, at least one cannabinoid, menthol, caffeine and vitamins, where the menthol component can be a stabilized menthol composition comprising menthol and at least one menthol stabilizer compound including undecylenic acid methyl ester, undecylenic acid or a salt of undecylenic acid.

Abstract: The present disclosure relates to compositions methods of use and methods of manufacturing, hydrous hydrogel compositions useful as topical oral analgesics including cannabinoids and menthol where the menthol component can be a stabilized menthol composition comprising menthol and at least one menthol stabilizer compound including undecylenic acid methyl ester, undecylenic acid or a salt of undecylenic acid.