Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems and methods for connecting a lead to an implantable medical device. The apparatuses, systems and methods may include a clamp arranged within a connector port configured to secure the lead with a header in response to frictional engagement between a portion of the implantable lead and the clamp.

Abstract: A body physiotherapy machine contains a conductive sphere member and a body configured to output electric physiotherapy energy to the conductive sphere member. The conductive sphere member is held by a user to contact his/her discomfort or acupuncture points so as to comfort the user and to enhance metabolism by ways of the electric physiotherapy energy, thus maintaining health easily.

Abstract: The present invention provides, among other things, apparatus and methods of use for treating a subject in need of assistance with breathing. In some embodiments the subject suffers from airflow obstruction. In some embodiments, the subject suffers from chronic obstructive pulmonary disease.

Abstract: An electrode for electrical stimulation therapy includes a sheet body of flat shape having a first surface facing a skin of a human body and a second surface at an opposite side to the first surface and at least one pair of flat electrodes that are provided at the first surface side of the sheet body and are mutually separated and the sheet body includes an expandable/contractible portion that is formed on a virtual axial line extending between the pair of flat electrodes and is expandable/contractible in a direction intersecting the virtual axial line. The electrical stimulation therapeutic device includes a device body and the electrode for electrical stimulation therapy electrically connected to the device body.

Abstract: A system for treating heart disease, such as pulmonary hypertension or right heart failure, including an implantable component and external components for monitoring the implantable component is provided. The implantable component may include a compliant member, e.g., balloon, coupled to a reservoir via a conduit. Preferably, the compliant member is adapted to be implanted in a pulmonary artery and the reservoir is adapted to be implanted subcutaneously. The external components may include a clinical controller component, monitoring software configured to run a clinician's computer, a patient monitoring device, and a mobile application configured to run on a patient's mobile device.

Abstract: Methods, apparatuses, systems, and implementations for inductive heating of a foreign metallic implant are disclosed. A foreign metallic implant may be heated via AMF pulses to ensure that the surface of the foreign metallic implant heats in a uniform manner. As the surface temperature of the foreign metallic implant rises, acoustic signatures may be detected by acoustic sensors that may indicate that tissue may be heating to an undesirable level approaching a boiling point. Once these acoustic signatures are detected, the AMF pulses may be shut off for a time period to allow the surface temperature of the implant to cool before applying additional AMF pulses. In this manner, the surface temperature of a foreign metallic implant may be uniformly heated to a temperature adequate to treat bacterial biofilm buildup on the surface of the foreign metallic implant without damaging surrounding tissue.

Abstract: A device and means to decrease the pain associated with cancer biopsies procedures The device uses anesthetic injections and electrical currents of both positive or negative polarity, or alternating current. The device can be incorporated into existing biopsiy devices. Application on breast cancer biopsies and other types of biopsies.

Abstract: A functional electrical stimulation (FES) device includes electrodes arranged to apply functional electrical stimulation to a body part of the user. FES stimulation is performed by: receiving values of a set of user metrics for the user; receiving a target position of the body part represented as values for a set of body part position measurements; determining a user-specific energization pattern for producing the target position based on the received target position and the received values of the set of user metrics for the user; and energizing the electrodes of the FES device in accordance with the determined user-specific energization pattern. The determination may utilize an FES calibration database with records having fields containing: values of the set of user metrics for reference users; energization patterns; and values of the set of body part position metrics for positions assumed by the body part in response to applying the energization patterns.

Abstract: A system for generating stimulations in relation to medicines, and meridians, organs and tissues of a human body includes a control device, a pulse examining device and a stimulation device. Based on a pulsation signal obtained from a user, the stimulation device obtains a meridian-related spectrum. Based on operation input to the control device, the stimulation device obtains an organ-tissue-related spectrum and a medication-related spectrum. The stimulation device obtains a stimulation spectrum by making a linear combination of these spectrums, and stimulates a sensory system of the user based on the stimulation spectrum.

Abstract: Apparatus is provided for treating an intervertebral disc of a subject, the apparatus including: at least one intra-pulposus exposed electrode surface, which is configured to be implanted in a nucleus pulposus of the intervertebral disc; and one or more extra-pulposus exposed electrode surfaces, which are configured to be implanted outside the nucleus pulposus, in electrical communication with the intervertebral disc. Control circuitry is electrically coupled to the at least one intra-pulposus exposed electrode surface and one or more extra-pulposus exposed electrode surfaces. The control circuitry is configured to drive fluid and introduce nutritional substances into the intervertebral disc, by applying a voltage between the at least one intra-pulposus exposed electrode surface and the one or more extra-pulposus exposed electrode surfaces. Other embodiments are also described.

Abstract: Methods for implanting a pulse generator (PG) within a pectoral region of a chest of a patient and devices having the PG. The PG has a housing that includes a PG electrode. Methods also include implanting at least one lead having first and second electrode segments with the first electrode segment positioned along an anterior of the chest of the patient and the second electrode segment positioned along at least one of a posterior of the patient or a side of the patient. The first and second electrode segments are positioned subcutaneously at or below an apex of a heart of the patient, wherein the PG electrode and the first and second electrode segments are configured to provide electrical shocks for antiarrhythmic therapy.

Abstract: This application is generally related to systems and methods for providing a medical therapy to a patient by tracking patient activity and adjusting medical therapy based on occurrence of different types of activities performed by the patient while automatically balancing stimulation program duration.

Abstract: Systems and methods for delivering targeted neurostimulation therapies to the nervous system of a subject are provided. A set of electrodes can be strategically distributed around a target nerve, and the nerve can be activated though the electrodes using a channel-hopping interleaved pulse scheduling (CHIPS) stimulation strategy. The systems and methods can leverage the spatiotemporal summation of short, sub-threshold current pulses interleaved across two or more independent stimulation channels (hopping from channel to channel) and delivered across electrodes strategically placed in an interfering configuration around the target neural tissue.

Abstract: Methods and apparatuses (e.g., devices and systems) for vagus nerve stimulation, including (but not limited to) sub-diaphragmatic vagus nerve stimulation. In particular, the methods and apparatuses described herein may be used to stimulate the posterior sub-diaphragmatic vagus nerve to treat inflammation and/or inflammatory disorders. The implantable microstimulators described herein may be leadless and batteryless.

Abstract: A myocardial excitation complementation/visualization apparatus includes an acquiring section that acquires intracardiac electrocardiograms of a subject, the intracardiac electrocardiograms being recorded by a recording unit having a plurality of electrodes, a processing section that performs a computation for completing and visualizing a state of excitation in a myocardium of the subject based on the intracardiac electrocardiograms, and a displaying section that displays the state of excitation in the myocardium of the subject based on an output of the processing section. The processing section includes a first generating section, a correcting section, a second generating section, and a third generating section. The displaying section displays a change of the state of excitation in the myocardium of the subject based on the visualized data.

Abstract: A topical nerve activation patch includes a flexible substrate, a dermis conforming bottom surface of the substrate comprising adhesive and adapted to contact a dermis of a user, a flexible top outer surface of the substrate, a plurality of electrodes positioned on the patch proximal to the bottom surface and located beneath the top outer surface and coupled to the flexible substrate, a power source, and electronic circuitry that generates an output voltage applied to the electrodes. The electronic circuitry includes a controller, a voltage monitoring circuit coupled to the controller, a current monitoring circuit coupled to the controller, a switch coupled to the controller and a two stage boosted voltage circuit coupled to the switch and the power source that is configured to increase a switch voltage level to approximately a half value of a final output voltage before increasing to the final output voltage.

Abstract: A method for configuring an electroanalgesia and electrotherapy apparatus using wireless control, with multiple stimulators, particularly used in the segment of pain control and aid in postoperative tissue repair and reduction of measures and body weight. According to the embodiments, a user with electrodes generically distributed simultaneously in several parts of the body, where at the pain site the frequency is from 80 Hz to 300 Hz or 1000 Hz and then to a range of 15 Hz to 35 Hz or among 0.5 Hz and 10 Hz on that electrode, and at distant points, for example, in upper or lower limbs the frequency is from 0.5 Hz to 10 Hz and, so the person can be submitted to this analgesia procedure, according to the pre-determined frequencies, pulse width and pulse form already pre-defined.

Abstract: Status messages are wirelessly broadcast from medical devices (e.g., defibrillators) as advertisements that don't require the establishment of a wireless connection with listeners. The listeners are configured to act on, or forward received status messages as appropriate. The listeners may optionally include supplemental information supplied by the listener device when forwarding a status message to a management server. The listener may optionally analyze received status messages to determine whether an action should be taken based at least in part on status information in the message. Actions performed by the listener may include initiating a connection with the transmitting device to facilitate uploading new information from the defibrillator, updating the defibrillator's firmware, etc. Optionally, some of the advertisements are configured as beacons. The advertisements/beacons may be transmitted using a Bluetooth Low Energy or other suitable protocols.

Abstract: Systems and methods for managing pain in patient are described. A system may include sensors configured to sense physiological or functional signals, and a pain analyzer to generate signal metrics from the physiological or functional signals. The pain analyzer also generates weight factors corresponding to the signal metrics. The weight factors may indicate the signal metrics reliability in representing an intensity of the pain. The pain analyzer generates a pain score using a plurality of signal metrics and a plurality of weight factors. The pain score may be output to a user or a process. The system may additionally include an electrostimulator to generate and deliver closed-loop pain therapy according to the pain score.

Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache, by electrical non-invasive stimulation of a nerve, such as the vagus nerve. A nerve stimulator is configured for coupling to a mobile device configured to receive a wireless signal, such as a mobile phone. The stimulator is further configured to generate an electrical impulse and to transmit the electrical impulse through one or more electrodes and the outer skin surface of the patient to modulate a nerve within the patient.