Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache, by electrical non-invasive stimulation of a nerve, such as the vagus nerve. A nerve stimulator is configured for coupling to a mobile device configured to receive a wireless signal, such as a mobile phone. The stimulator is further configured to generate an electrical impulse and to transmit the electrical impulse through the contact surface and the outer skin surface of the patient to modulate a nerve within the patient.

Abstract: An intracorporeal device is provided for supporting heart function of a patient. The intracorporeal device is configured to be secured across at least two anatomical walls of the heart. The intracorporeal device is configured to be secured to one or more anatomical walls by a connector. The connector is arranged to be positioned across one or more anatomical walls.

Abstract: An electrode is provided that includes a wire that has a wire diameter of between 75 and 125 microns. The electrode includes a non-electrically-insulated current-application longitudinal segment, which, in the absence of any applied forces, is coiled and has (i) an outer coil diameter of between 3 and 7 times the wire diameter, and (ii) an entire longitudinal length of between 5 and 35 mm. The electrode further includes an electrically-insulated lead longitudinal segment, which has an entire longitudinal length of at least 10 mm, in the absence of any applied forces. Other embodiments are also described.

Abstract: Autonomic nervous system control via high frequency spinal cord modulation, and associated systems and methods. A method for treating a patient in accordance with a particular embodiment includes selecting a neural modulation site to include a neural population of the patient's spinal cord, and selecting parameters of a neural modulation signal to at least reduce an autonomic system deficit in the patient.

Abstract: Apparatus for transcutaneous electrical nerve stimulation in a user, the apparatus comprising: a housing; stimulation means for electrically stimulating at least one nerve; an electrode releasably mounted to the housing and connectable to the stimulation means for electrical stimulation of the at least one nerve; monitoring means for monitoring the user's body orientation and movement; analysis means for analyzing said orientation and movement; and control means for controlling the output of the stimulation means in response to said analysis of said orientation and movement.

Abstract: The present invention provides systems and methods for monitoring cardiac autonomic nervous system activity and modulating parasympathetic control of cardiac function.

Abstract: A shared resource medical system for monitoring a patient during emergency situations includes a portable defibrillator and an ultrasound transducer physically and communicatively coupled to the defibrillator. The defibrillator includes sensors, a display screen, a power supply, a data storage device, and a defibrillator processor operatively coupled to the screen, the power supply, and the storage device and configured to receive and process user input, receive patient physiological data from the sensors, and generate an interface on the display screen. The ultrasound transducer is configured to obtain ultrasound physiological data of the patient and send the ultrasound physiological data to the defibrillator processor.

Abstract: A noxipoint stimulating device uses light, mechanical force, and heat as a source of stimulating energy, which is configured to be applied on the Noxipoints.

Abstract: A neuro activation system includes a patch adapted to be applied externally on a dermis of a user, the patch comprising a flexible substrate and an adhesive on a first side adapted to adhere to the dermis of the user, an electronic package directly coupled to the substrate, the electronic package including a control unit and one or more stimulators, and electrodes directly coupled to the substrate and the electronic package, the patch adapted to generate an electrical stimuli via the electrodes. The neuro activation system further includes a controller in wireless communication with the patch, the controller including remote functionality to start and stop the electrical stimuli.

Abstract: A monitoring device for monitoring the readiness state of an automated external defibrillator (AED) and communicating the state to a remote receiver is described. The method uses a fault identification logic operable to detect an AED with a depleted battery. An associated method is described as well. The monitoring device captures both of a parameter related to the activation of the AED fault alert indicator and a second parameter that indicates a positive AED battery state.

Abstract: A method for positioning an electrode array of a neuromodulation catheter at a target circumferential position along a posterior wall of a blood vessel. The method includes advancing the catheter to a target longitudinal position within the blood vessel and positioning the array within the blood vessel so as to minimize interference by CRM leads or coils in the blood vessel during therapeutic delivery of energy using the array.

Abstract: A wavelength converting bandage including a substrate with an external surface and an internal surface. The wavelength converting bandage includes a plurality of quantum dots, each quantum dot individually sized to emit light within a wavelength range of 613 nm to 846 nm, defined as converted light. The wavelength converting bandage includes at least a portion of the substrate constructed to adhere to skin. The substrate may receive ambient light from the environment on the external surface and may emit converted light toward the skin.

Abstract: A device for electrical stimulation of one or more components of the periodontal complex and surrounding tissue of a tooth, for uses such as reducing orthodontic pain and encouraging tooth movement, has electrodes of a rigid, electrically conductive material in a fixed spatial relationship configured for application to oral mucosa and attached gingiva adjacent to, and along a periodontal ligament of, a root structure of a single tooth. An electrical circuit is configured for electrical connection to the at least two electrodes. The electrical circuit has an output providing a subsensory electrical stimulus comprising a waveform in accordance with predetermined stimulation parameters. After the electrodes are applied to the oral mucosa and attached gingiva adjacent to, and along the periodontal ligament of, a root structure of the tooth, a switch, when activated, activates the electrical circuit to output the electrical stimulus through the at least two electrodes.

Abstract: A method to measure sound-producing behaviors of a subject with a power- and bandwidth-limited electronic device that includes a processor includes measuring, by a microphone communicatively coupled to the processor, sound in a vicinity of the subject to generate an audio data signal that represents the sound. The method also includes measuring, by at least one second sensor communicatively coupled to the processor, at least one parameter other than sound to generate at least a second data signal that represents the at least one parameter other than sound. The method also includes detecting one or more sound-producing behaviors of the subject based on: both the audio data signal and the second data signal; or information derived from both the audio data signal and the second data signal.

Abstract: Diagnostic screening tests that can be used to identify if a patient is a good candidates for an implantable vagus nerve stimulation device. One or more analyte, such as a cytokine or inflammatory molecule, can be measured from a blood sample taken prior to implantation of a vagus nerve stimulator to determine the patient's responsiveness to VNS for treatment of an inflammatory disorder.

Abstract: A device and means to decrease the pain associated with dental procedures as from dental drills, the probing scratching tool to detect cavities, the needle to inject anesthesia, the tool to extract nerve for root canal treatment, etc. The device uses electrical currents of both positive and negative polarity or alternating current.

Abstract: An apparatus is described comprising electrodes (22) configured to be placed upon a portion of a body of a subject, and a user interface device (26). A computer processor (24) applies a neuromodulation treatment to the subject, by driving electrical pulses into the portion of the subject's body via the electrodes, and generates an output on the user interface device that indicates to the subject a physiological effect that the neuromodulation treatment has upon the subject's body.

Abstract: Applying therapeutic neural stimuli involves monitoring for at least one of sensory input and movement of a user. In response to detection of sensory input or user movement, an increased stimulus dosage is delivered within a period of time corresponding to a duration of time for which the detected sensory input or user movement gives rise to masking, the increased stimulus dosage being configured to give rise to increased neural recruitment.

Abstract: An implantable stimulation system having an implantable stimulation unit coupled to a programmable controller, a stimulation circuit and an array of electrodes disposed on a pair of flexible paddles is provided for selectively stimulating at least one cavernous nerve. The programmable controller is pre-programmed to run an excitation electrode routine that selectively scans the electrode arrays on the paddles with a series of directional current flows, in at least two directions and within at least two regions, to optimize electrode selection for use in stimulating the cavernous nerve. The implantable stimulation system may be programmed to run a first stimulation pulse sequence corresponding to a first mode for invoking a rapid erectile response, and optionally, a second nerve rehabilitation stimulation mode selected to rehabilitate neural transmission in a cavernous nerve, and/or a third penile rehabilitation mode selected to reduce penile fibrosis. Methods of operating the system also are provided.

Abstract: In an example, an n-dimensional method of fundamental solution (MFS) is used to compute reconstructed electrical activity on a cardiac envelope based on geometry data and electrical data, where n is a positive integer greater than three. The electrical data represents electrical activity measured non-invasively from a plurality of locations distributed on a body surface of a patient, and the geometry data represents three-dimensional body surface geometry for the locations distributed on the body surface where the electrical activity is measured and three-dimensional heart geometry for the cardiac envelope.