Patents Examined by Natalie Trousof
  • Patent number: 4665244
    Abstract: Hexadecene derivatives of the formulae: ##STR1## and ##STR2## in which X and X.sub.1, which may be identical or different, each represent hydrogen or chlorine, and their mixtures, are useful in the preparation of tocopherol and tocopherol acetate.
    Type: Grant
    Filed: September 19, 1985
    Date of Patent: May 12, 1987
    Assignee: Rhone-Poulenc Sante
    Inventors: Pierre Chabardes, Michel Mulhauser
  • Patent number: 4663350
    Abstract: Diphenylazomethine derivatives of formula (I) ##STR1## wherein R.sub.1 is hydrogen or methyl and R.sub.2 is an --OH,--OM (M=alkaline metal or alkaline earth metal), --NH.sub.2 or --O(C.sub.1-4 alkyl) group, and which are in the form of cis or trans isomers or mixtures thereof, have central nervous system activity and can be used as antidepressants and anticonvulsants.
    Type: Grant
    Filed: September 26, 1985
    Date of Patent: May 5, 1987
    Assignee: Synthelabo
    Inventors: Alexander Wick, Bernard Raizon
  • Patent number: 4663432
    Abstract: Polymeric phosphonate anhydrides are formed by dehydrating a reaction mixture comprising a salt of a diphosphonic acid. The invention includes the polymeric phosphonate, its method of preparation, and a primary use.
    Type: Grant
    Filed: August 19, 1985
    Date of Patent: May 5, 1987
    Assignee: Monsanto Company
    Inventor: James P. Coleman
  • Patent number: 4663351
    Abstract: A novel, orally administrable pro-drug form of dobutamine of the formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof.
    Type: Grant
    Filed: August 23, 1985
    Date of Patent: May 5, 1987
    Assignee: Berlex Laboratories, Inc.
    Inventor: Julius Diamond
  • Patent number: 4663477
    Abstract: A process is provided for the utilization of dialkyl carbonates formed as by-products in a continuous process for the synthesis of oxalic acid esters from nitrous acid esters and carbon monoxide and wherein the esters are subsequently used as intermediates in the production of commercially useful products, such as ethylene glycol. The process comprises contacting a mixture containing the by-product comprised of a dialkyl carbonate with an aqueous solution of a metal carbonate under hydrolyzing conditions whereby the dialkyl carbonate is converted to the corresponding alkanol and the metal carbonate is converted to metal bicarbonate. Upon distillation of the alkanol from the mixture the bicarbonate is converted back to the metal carbonate which can then be recycled from the bottoms to the hydrolyzing zone for use in further hydrolysis of by-product. The alkanol is recycled for use in the continuous process.
    Type: Grant
    Filed: March 27, 1986
    Date of Patent: May 5, 1987
    Assignee: Union Carbide Corporation
    Inventors: John W. Crandall, James E. Deitzler, Louis A. Kapicak, Fedor Poppelsdorf
  • Patent number: 4663476
    Abstract: Described are methylthioalkanoic acid esters of cis-3-hexenol and citronellol defined according to the structure: ##STR1## wherein R.sub.2 represents cis-3-hexenyl or cutronellyl and uses thereof in augmenting or enhancing the aroma or taste of foodstuffs.
    Type: Grant
    Filed: March 21, 1986
    Date of Patent: May 5, 1987
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Alan O. Pittet, Ranya Muralidhara, Manfred H. Vock
  • Patent number: 4661628
    Abstract: A new process for the optical resolution of racemic mixtures of .alpha.-naphthyl-propionic acids of formula ##STR1## This process comprises reacting a racemic mixture of a compound of formula ##STR2## with an optically active substance of formula R.sub.4 --NH.sub.2 (III), said substance being a .beta.-aminoalcohol, thus forming a pair of diastereoisomeric amides which are resolved into the single diastereoisomers by fractional crystallization. The obtained single diastereoisomeric amide is then hydrolyzed to give the desired optically active .alpha.-naphthyl-propionic acid of formula ##STR3## In the above compound I.fwdarw.III and VI, R.sub.1 is (C.sub.1-6)alkyl, R.sub.2 stands for hydrogen, halogen, mercapto, (C.sub.1-6)alkylthio, phenylthio, benzylthio, (C.sub.1-6)alkylsulfonyl, benzenesulfonyl, benzenesulfonyl substituted by halogen or (C.sub.1-4)alkyl, R.sub.3 is a reactive group and R.sub.4 is the residue of a primary or secondary alcohol.
    Type: Grant
    Filed: November 5, 1984
    Date of Patent: April 28, 1987
    Assignee: Alfa Chemicals Italiana S.p.A.
    Inventors: Vincenzo Cannata, Giancarlo Tamerlani
  • Patent number: 4661622
    Abstract: A novel method for producing a composite ester from dibasic acid, diol and monovalent alcohol through a dehydrating esterification reaction in the first step and then alcohol removing ester interchange reaction in the second step.
    Type: Grant
    Filed: January 31, 1986
    Date of Patent: April 28, 1987
    Inventor: Satoshi Matsumoto
  • Patent number: 4661522
    Abstract: The present invention is dealing with cycloalkane-indene-carboximidamide derivatives having the general formula: ##STR1## wherein Rx together with either Ry.sub.1 or Ry.sub.2 represent the moiety ##STR2## (the other Ry being hydrogen), n represents the number 1, 2 or 3,R represents hydrogen or a (1-4 C)-alkyl group,R.sub.1 represents hydrogen, (1-4 C)-alkyl, hydroxyl, (1-4 C)-alkoxy or an amino group which is unsubstituted or substituted by (1-4 C)-alkyl andR.sub.2 is hydrogen, hydroxyl or (1-4 C)-alkyl,as well as the pharmaceutically acceptable salts thereof, with powerful blood platelet aggregation-inhibiting activity.
    Type: Grant
    Filed: May 15, 1985
    Date of Patent: April 28, 1987
    Assignee: Akzo N.V.
    Inventor: Tom Beetz
  • Patent number: 4661272
    Abstract: Provided is a novel thioether diester synthetic lubricating oil composition represented by the formula: ##STR1## in which R and R.sub.1 each represent alkyl radicals having from 1 to 6 carbon atoms, with the total number of carbon atoms in R, R, R.sub.1, and R.sub.1 ranging from about 6 to 20, and n is an integer from 2 to 5.
    Type: Grant
    Filed: June 22, 1983
    Date of Patent: April 28, 1987
    Assignee: Texaco Inc.
    Inventors: Edward T. Marquis, Lewis W. Watts, Jr., Ernest L. Yeakey
  • Patent number: 4659741
    Abstract: This invention is concerned with new .beta.-[2-(halogenobenzyl)-phenoxy]-ylamine derivatives of the general formula ##STR1## wherein R represents a C.sub.1 -C.sub.8 -alkyl group having a linear or branched hydrocarbon chain,R.sub.1 and R.sub.2, which may identical or different, represent each a C.sub.1 -C.sub.4 -alkyl-group, andAr represents a polychlorophenyl group of the formula ##STR2## (in which Y.sub.1 is 4-Cl, Y.sub.2 is H or Cl, and Y.sub.3 is H or Cl, at least one of the Y.sub.2 and Y.sub.3 being Cl); and their addition salts.These new compounds are useful as pharmaceuticals.
    Type: Grant
    Filed: November 27, 1984
    Date of Patent: April 21, 1987
    Assignee: Institut de Recherches Chimiques et Biologiques Appliquees (I.R.C.E.B.A)
    Inventors: Jean-Yves Lacolle, Bernard Danree
  • Patent number: 4659372
    Abstract: 2-Aryl-1,3-cyclohexanedione enol ester compounds exhibit outstanding miticidal, mite ovicidal and herbicidal activity.
    Type: Grant
    Filed: November 28, 1983
    Date of Patent: April 21, 1987
    Assignee: Union Carbide Corporation
    Inventor: Thomas N. Wheeler
  • Patent number: 4659855
    Abstract: Certain novel aryl sulfonyl fluorides, their preparation, and their use in inhibiting serine proteases with chymotrypsin-like and elastase-like specificity.
    Type: Grant
    Filed: May 9, 1983
    Date of Patent: April 21, 1987
    Assignee: Georgia Tech Research Corporation
    Inventor: James C. Powers
  • Patent number: 4658054
    Abstract: A process for the preparation of 5,6-dialkoxyanthranilic acids is described. The 5,6-dialkoxyanthranilic acids are useful in the preparation of substituted quinazolinediones which are active cardiotonic agents.
    Type: Grant
    Filed: July 29, 1985
    Date of Patent: April 14, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventor: Richard A. Conley
  • Patent number: 4658055
    Abstract: A method for the manufacture of a heptanoic acid derivative represented by the formula ##STR1## wherein R.sup.3 stands for an acyloxy group, a halogen atom, or a hydrogen atom, which comprises reacting a cyclooctene derivative represented by the formula ##STR2## wherein Y stands for --R.sup.1, --COR.sup.1 or --SiR.sup.2.sub.3, wherein R.sup.1 is an alkyl group, an aryl group, or an aralkyl group and R.sup.2 is an alkyl group of 1 to 5 carbon atoms, with a compound represented by the formula ##STR3## wherein R.sup.3 has the same meaning as indicated above and X.sup.1 and X.sup.2 each is a halogen atom, is described along with uses for such compounds.
    Type: Grant
    Filed: January 28, 1985
    Date of Patent: April 14, 1987
    Assignee: Ajinomoto Co., Inc.
    Inventors: Takashi Onuki, Hirokazu Naora, Asao Nakamura
  • Patent number: 4658080
    Abstract: A catalyst for removing acetylenic impurities from gaseous organic product streams, comprising at least Fe and Ni, other elements from Groups 8, 1b, 2b, 4b, 6b and 7b of the Periodic Table, an alkaline earth metal and an alkali metal.
    Type: Grant
    Filed: August 15, 1983
    Date of Patent: April 14, 1987
    Assignee: Petro-Tex Chemical Corporation
    Inventor: Cecil G. McFarland
  • Patent number: 4657708
    Abstract: Aromatic monomers, each containing at least one o-ethynyl carboxylic acid halide subunit: ##STR1## wherein X is Cl or Br. These monomers can be reacted with amines to form aromatic polyamide resins which can be thermally treated to undergo intromolecular cyclization, without evolution of volatiles, into polyimidines.
    Type: Grant
    Filed: December 10, 1985
    Date of Patent: April 14, 1987
    Assignee: The United States of America as represented by the Secretary of the Air Force
    Inventors: Robert C. Evers, George J. Moore
  • Patent number: 4657702
    Abstract: An aqueous dispersion of unreacted particulate petroleum coke substantially comprising carbon and containing a small amount of ash substantially comprising vanadium constituents and other materials from a process for the partial oxidation of petroleum coke to produce synthesis gas is mixed with a K.sup.+ amyl xanthate vanadium collection agent and a frothing agent. After pH adjustment, if necessary, the mixture is subjected to aeration with or without mechanical agitation in a froth flotation zone. About 70 to 95 wt. % of the unconverted particulate petroleum coke particles (basis carbon) float in the froth layer that is formed. The remainder of the unconverted petroleum coke comprising coarser particles is suspended in a bottom aqueous dispersion on which the froth layer floats. In addition, selective separation of the vanadium constituents in the unconverted petroleum coke ash takes place.
    Type: Grant
    Filed: April 26, 1985
    Date of Patent: April 14, 1987
    Assignee: Texaco Inc.
    Inventors: Stephen R. Vasconcellos, Mitri S. Najjar, James R. Pascoe
  • Patent number: 4655972
    Abstract: Carbonamides are prepared from carboxylic acids and ammonia in the presence of a catalytic amount of a hydrated oxide.Preferably a hydrated titanium-, zirconium- or tin oxide in an amount between 0.05 to 10% by weight is used. The hydrated oxide contains at least 4% of water.
    Type: Grant
    Filed: July 3, 1984
    Date of Patent: April 7, 1987
    Assignee: Internationale Octrooi Maatschappij "Octropa" B.V.
    Inventors: Teunis Eikelboom, John A. Rand, Pieter M. van Dijk
  • Patent number: 4656307
    Abstract: According to the invention a derivative of brendane is provided. The derivative of brendane is represented by the general formula of: ##STR1## wherein R is a hydrogen atom or a hydrocarbon group having 1 to 6 carbon atoms, and R.sup.1 to R.sup.3 each represent a hydrogen atom or a methyl group. The brendane derivative is prepared by reacting an alkenylnorbornene of the general formula of: ##STR2## wherein R.sup.1 to R.sup.3 each represent a hydrogen atom or a methyl group, with carbon monoxide and an alcohol or water in the presence of a catalyst of Group VIII metal compound of the periodic table.
    Type: Grant
    Filed: July 15, 1985
    Date of Patent: April 7, 1987
    Assignee: Nippon Oil Co., Ltd.
    Inventors: Yoshihiro Kobori, Tetsuya Takezono