Abstract: Embodiments of the present invention are directed to the treatment of hypertension, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pains, asthma, pulmonary arterial hypertension, and chronic obstructive pulmonary disease by delivering of an effective amount of formulations at desired temperature to target tissue. The formulations include gases, vapors, liquids, solutions, emulsions and suspensions of one or more ingredients. The temperature may enhance safety and efficacy of the formulations for the treatments. The amounts of the formulation and/or energy are effective to injury or damage the tissues to have a benefit of symptom relive.

Abstract: A fluid pumping system may comprise a pump and a fluid line state detector having, a receptacle, at sensor, and an illuminator. The system may further comprise a fluid transfer set including an output line for mating into the receptacle. The system may further comprise a controller in data communication with the fluid line state detector configured to power the illuminator and monitor an output signal of the sensor when the outlet line is in the receptacle to determine a dry tube light intensity value. The controller may be further configured to govern operation of the pump to prime the output line with fluid. The controller may be further configured to power the illuminator, monitor the output signal, and halt operation of the pump when the output signal indicates the light intensity value has dropped below a primed line threshold which is dependent upon the dry tube intensity value.

Abstract: A medical fluid suspension generating apparatus for performing medical procedures includes a Venturi-agitating tip assembly composed of a multi-channel arrangement at a proximal first end thereof and a tip at a distal second end thereof. The apparatus also includes a compressed medical fluid unit fluidly connected to the multi-channel arrangement at a proximal first end of the Venturi-agitating tip assembly and a medical solution fluidly connected to the multi-channel arrangement at a proximal first end of the Venturi-agitating tip assembly. Pressurized gas, from the compressed medical fluid unit, and the medical solution are combined within the Venturi-agitating tip assembly in a manner generating an enriched medical suspension that is ultimately dispensed from the suspension delivery apparatus.

Abstract: The present disclosure includes an expandable medical device and outer sheath combination. The outer sheath is capable of being split to form multiple sheath sections that may be peeled back to expose a portion or all of the expandable medical device. The medical device, as well as the outer sheath, may include one or more therapeutic agents for delivery to a treatment area within a patient.

Abstract: A needleless injector pressurizes a substance to be injected having an ejection pressure defined as a pressure of the substance to be injected ejected through an ejection port. The ejection pressure is raised to a first peak pressure after pressurizing is started, is lowered to a pressure lower than the first peak pressure afterward, and then is raised to a second peak pressure again. An on-completion reached depth that is an on-completion reached depth of the substance when the pressurizing portion completes pressurizing is adjustable, the on-completion reached depth being increased along with increase of the first peak pressure and being increased along with reduction of a length between peaks from a first timing at which the ejection pressure reaches the first peak pressure to a second timing at which the ejection pressure reaches the second peak pressure.

Abstract: IV filters are described herein. An IV filter includes a body, a filter media, and a bulb. The body defines a body volume. The filter media is disposed within the body volume. The filter media defines an inlet portion of the body volume and an outlet portion of the body volume. The filter media permits inlet flow from the inlet portion of the body volume to the outlet portion of the body volume and captures particulate from the inlet flow. The bulb defines a bulb volume in fluid communication with the outlet portion of the body volume. The bulb is deformable to compress the bulb volume and direct back flow from the outlet portion of the body volume through the filter media and into the inlet portion of the body volume, displacing particulate captured in the filter media into the inlet portion of the body volume.

Abstract: An elongate medical device comprising a first lumen, wherein a cross-sectional shape of the first lumen comprises a peanut shape, and a plurality of second lumens, wherein the plurality of second lumens are proximate the first lumen, wherein the first lumen comprises a lumen liner that conforms to the cross-sectional shape of the first lumen, wherein the lumen liner comprises a first material and the elongate medical device comprises a second material, where the first material is different from the second material.

Abstract: Embodiments including an injection device having a housing with an outer surface, an inner surface, a proximal end and a distal end, and a defining a chamber extending between the proximal end and the distal end are provided herein. The device may include a plunger having a first end and a second end, the plunger being movable proximally and distally within the chamber of the housing, the plunger comprising a plunger rod extending from the first end to the second end of the plunger; and a plunger limiting mechanism configured to interface with the plunger rod, to limit the proximal movement of the plunger and prevent removal of the plunger from the housing.

Abstract: A medication delivery device (MDD) (e.g., injection pen, wearable pump) is paired with an external device (e.g., smart phone, iPad, computer) via wireless link or wireline connection. The MDD provides to the external device captured data from the flow sensor relating to medicine delivery to a patient to ensure complete delivery and minimize MDD misuse or malfunction or inaccuracies in dosing. The MDD can have Bluetooth™ and/or near field communication (NFC) communication circuits for proximity-based pairing and connectivity with the external device for real-time or deferred transfer of captured data to the external device, depending on memory and power availability at the MDD. The MDD or external device can use captured data and corresponding time stamps to determine flow infomatics such as flow rate, total dose delivered, and dose completion status. An LED on the MDD indicates states such as powered on, paired, delivery in progress and delivery completion.

Abstract: Systems and methods for pumping milk from a breast, wherein the milk is expressed from the breast under suction and milk is expulsed from the pumping mechanism to a collection container under positive pressure.

Abstract: A modular medical device system comprises a parent module with a proximal end configured to remain outside the body of a patient and a distal end configured to go inside the body of a patient, the distal end comprising an inner lumen; and an adapter module comprising a proximal portion and a distal portion, an attachment mechanism positioned at the proximal portion and comprising an interfacing element and an elongated element, wherein at least a portion of the interfacing element compresses to engage the inner lumen of the parent module, and wherein the elongated element connects the attachment mechanism to the distal portion of the adapter module.

Abstract: The invention relates to an auto injector, by which a fixed dose of a medicament can be injected as self-treatment, and by which needle exposure to an accessible position, injection of the medicament and retraction of the needle to an inaccessible position is automatically performed as a continuous sequence, after the auto injector is triggered. The invention provides solutions to improve the functionality of the retraction of the needle and the general experience of the use.

Abstract: A method for performing an intravascular procedure includes inserting a guide catheter into a blood vessel, and passing a device guide through the guide catheter so that a distal portion of the device guide, having a semi-tubular shape, protrudes from a distal end of the guide catheter into the blood vessel. An intravascular device is inserted through the guide catheter via the distal portion of the device guide to a target site in the blood vessel.

Abstract: A multi-tubing intravenous (IV) extension set may include an outlet tubing fluidly coupled to a primary multi-tubing connector at one end and fluidly coupled to a vascular device at an opposite end, and a primary inlet tubing having a proximal end with an adapter for connection to a syringe containing a priming or a medicinal fluid, and a distal end coupled to the primary multi-tubing connector. The IV extension set may further include at least one secondary inlet tubing with a proximal end having an adapter for receiving a medicinal fluid and a distal end selectively fluidly coupled to the primary multi-tubing connector. A slide clamp may be positioned on the outlet tubing to restrict flow between the proximal and distal ends of the outlet tubing and cause priming fluid flowing into the outlet tubing via the multi-tubing connector to reverse direction into the at least one secondary inlet tubing.

Abstract: A method of changing a catheter into a distal steering tool catheter includes adding to an existing catheter a tube assembly that passes through the catheter, the tube assembly including an internal tube and an external tube whose distal ends are coupled to each other and which are arranged for longitudinal axial movement relative to one another, and providing a tube manipulator coupled to the tube assembly, which is operative to cause relative axial movement of the internal and external tubes and bending of a distal portion of at least one of the internal and external tubes.

Abstract: The present invention provides a power unit (1) for a drug delivery device as well as methods for providing and mounting the power unit (1) in the drug delivery device. The power unit (1) comprises a first interface member (30) extending along a reference axis and comprising a hollow body (31) and a first engagement structure (35), a second interface member (10) comprising a tubular structure (11) extending at least partially through the hollow body (31) and having a skirt (12), and a second engagement structure (14) configured for releasable engagement with the first engagement structure (35), and a torsion spring (20) comprising a first end portion (23) being attached to the first interface member (30) and a second end portion (22) being attached to the second interface member (10), the torsion spring (20) being pre-strained to induce a relative rotational motion between the first interface member (30) and the second interface member (10).

Abstract: An apparatus for irrigating the vas deferens in connection with a vasectomy reversal is described. The apparatus comprises a fluid delivery device having a first portion that connects to the vas deferens, the fluid delivery device connecting such that a catheter tip inserts into the vas deferens and is held in stable position relative thereto and such that fluid enters the vas deferens through the catheter tip.

Abstract: A part of a device for injecting a liquid product having an end sleeve and a syringe support which is able to move with respect to the end sleeve. The syringe support is designed to bear an injection syringe fitted with a removable protective cap. A deformable ring is kinematically connected to the syringe support. This ring can be deformed elastically between a configuration which is designed to axially immobilize the injection syringe in the syringe support, and a configuration designed to allow the protective cap to pass through the deformable ring.

Abstract: An infusion system for subcutaneous delivery of a fluid to a subject is disclosed. The infusion system comprises a source of a fluid; a fluid delivery system; a first fluid conduit in fluid communication with the source of the fluid and the fluid delivery system; a fluid injection device configured to be inserted into the skin of a subject for delivering the fluid to the subject; a second fluid conduit in fluid communication with the fluid delivery system and the fluid injection device; and a support frame attached to the source of the fluid and the fluid delivery system, wherein the support frame is configured to mount the source of the fluid and the fluid delivery system on a region of a head of the subject. The fluid delivery system moves the fluid from the source of the fluid, through the first fluid conduit, through the second fluid conduit, and through the fluid injection device.

Abstract: An infusion pump (18) for delivery of a fluid is disclosed. The infusion pump allows a user to selectively control a flow rate of a fluid and includes a spike member (26) that is connectable to an injection port of an intravenous fluid container (12).