Abstract: In an embodiment, a medicament delivery system is provided. The medicament delivery system includes a container for storing a medicament prior to use, the container having a first end and a second end, an injection member in fluid communication with the container, an actuation mechanism associated with the container and configured to deliver the medicament from the container through the injection member when the actuation mechanism is activated. The medicament delivery system further includes at least one detection element associated with the system, wherein in a first mode of operation of the system, medicament is delivered through the injection member and in a second mode of operation of the system, medicament is not delivered through the injection member, and the mode of operation is dependent on an output from the at least one detection element.

Abstract: An axial support structure for a flexible elongate device includes a plurality of rigid links. each link comprises a shaft, a pair of male joint connectors comprising a male tab coplanar with the shaft extending from a first end, and a pair of female joint connectors comprising a female tab coplanar with the shaft extending from a second end. Each of the male joint connectors includes a pin extending from the male tab in a direction perpendicular to an axial direction of the shaft and each female tab defines an aperture. Each of the plurality of rigid links is rotated by 90 degrees with respect to neighboring links among the plurality of rigid links, thereby aligning each pair of male joint connectors with a neighboring pair of female joint connectors to form pin joints in which each aperture encircles a corresponding pin.

Abstract: The housing for mounting an elongate-shaped container on an injection pen comprises an elongate-shaped body which extends along a longitudinal axis (X30) and which defines an interior volume (V32) for fully receiving the container. The body is provided, on the outside of a first axial end, with at least one first mechanical member for attaching a needle. The body is further provided, in the vicinity of a second axial end opposite the first axial end, with at least one second mechanical member for attaching the housing onto an injection pen. The housing further comprises, in the vicinity of the first axial end thereof, at least one third mechanical member for irreversibly locking a container in position, fully contained in the interior volume (V32) of the body of the housing. Said third locking member is formed by an elastically deformable tab intended to ensure locking of the container in position in the interior volume (V32) of the body of the housing, by axially retaining a flange of the container.

Abstract: Disclosed are devices, systems, and methods for providing access to a patient. The patient access device comprises a proximal end, a distal end and a lumen therethrough. The patient access device further comprises a hollow shaft, an input port and a liquid supply port. At least a portion of the lumen passes through the shaft. The input port is coupled to the lumen, and the lumen and the input port are constructed and arranged to receive an elongate probe. The liquid supply port is in fluid communication with the lumen. The patient access is constructed and arranged to reduce gas from exiting the distal end while a portion of the elongate probe is positioned in the patient access device.

Abstract: A patient temperature control system and method are provided for automated temperature control according to a programmed protocol. In one aspect, at least one programmed protocol may be established for each of a plurality of patient thermal therapy phases. In turn, the temperature of a thermal exchange medium may be controlled, based at least in part, upon the programmed protocol, during each of the phases. In another aspect, a plurality of programmed protocols may be established, wherein a selected one of the protocols (e.g. selected by a user at a user interface) may be utilized for automated temperature control during patient thermal therapy. The protocol(s) may include a target patient temperature and/or a set duration for one or more of the phase of thermal therapy. Further, the protocol(s) may be user-definable and modifiable during therapy.

Abstract: A method of securing an infusion set to a skin surface, comprising the steps of placing a needle or cannula of the infusion set in the skin surface, and controlling a minimum bend radius of the placed needle or cannula to resist deformation and fracture thereof.

Abstract: An inserter for inserting a needle or cannula of an infusion set comprises a fixed inserter member and a movable inserter member movably connected to said fixed inserter member and adapted to receive the infusion set. The movable inserter member is movable from a first position to a second position to expose the needle or cannula. The movable inserter member is locked to the fixed inserter member in the first position to prevent accidentally exposing the needle or cannula.

Abstract: A hub assembly is provided for accommodating a medical professional to grip and manipulate two components of a catheter hub and move one component longitudinally relative to the other, then removably engaging the two components of the catheter hub to restrict movement there between. The two catheter hub components include a proximal hub and a distal hub. The proximal hub and the distal hub are configured to removably engage with one another. The proximal hub is affixed to a first catheter member, such as a multi-lumen catheter, while the distal hub is affixed to a second catheter member, such as a sheath. The first catheter member and the second catheter member are cooperatively engaged and concentric with one another. Relative movement of the proximal and distal hubs translates into relative movement of the first and second catheter members.

Abstract: An ophthalmic device including a cannula having a cannula distal end, a lumen, and one or more orifices coupled to the lumen is provided. The cannula is configured to deliver a fluid. A sleeve is disposed around the cannula and has a sleeve distal end. A handle is coupled to the sleeve and the cannula, the handle having an actuator. An internal mechanism is coupled to the actuator and configured to retract the sleeve relative to the cannula. The internal mechanism includes a follower fixedly coupled to the sleeve and moveable between distal and proximal positions, and a release member movable between an activated position and a release position. The release member is coupled to the actuator and configured to release a force that urges the follower from the distal position to the proximal position when the release member moves from the activated position to the release position.

Abstract: An ophthalmic device including a cannula having a cannula distal end, a lumen, and one or more orifices coupled to the lumen is provided. The cannula is configured to deliver a fluid. A sleeve is disposed around the cannula and has a sleeve distal end. A handle is coupled to the sleeve and the cannula, the handle having an actuator. An internal mechanism is coupled to the actuator and configured to retract the sleeve relative to the cannula. The internal mechanism includes a follower fixedly coupled to the sleeve and moveable between distal and proximal positions, and a release member movable between an activated position and a release position. The release member is coupled to the actuator and configured to release a force that urges the follower from the distal position to the proximal position when the release member moves from the activated position to the release position.

Abstract: A cannula insertion device is disclosed. The device includes a needle carriage, a rail device on which the needle carriage is slidable, a yoke having a channel, a linkage connected to the needle carriage and extending into the channel, a torsion spring with one end connected to the linkage, and locking device for locking the torsion spring in tension and maintaining the needle carriage and the linkage in a locked position prior to activation. Upon release of the locking device, the tension of the torsion spring is released, which causes the linkage to move in the channel and slide the needle carriage along the rail device. A catheter carriage may also be provided for actuation by the linkage.

Abstract: An injection device (1) includes a housing (20) for receiving a cartridge (30) of medicament in use; a drive element (12), moveable from a first position to a second position to expel a dose from said cartridge, and wherein the drive element comprises an electrically-operated indicator module (40) for generating an indication corresponding to the stage of use of the device. The indicator module (40) may be contained within the drive element, for example within an interior of the drive element and may include an audible indicator such as e.g. a sounder or loudspeaker, and a visual indicator such as e.g. one or more LEDs arranged to provide e.g. colour-coded signals.

Abstract: The invention provides an injection device for delivering a dose of medicament from a syringe. The injection device comprises a housing (10), a plunger (110) moveably mounted within the housing, an actuation mechanism (120, 122) arranged to provide a forward biasing force to urge the plunger forward in use to express a dose of medicament and a trigger mechanism (40) arranged to (directly or indirectly) releaseably hold the plunger against the force of the actuation mechanism. The injection device further comprises a plunger velocity regulator comprising a cam surface (162) associated with one of the housing or the plunger, and a cam member (152) associated with the other of the plunger or the housing and arranged to engage the cam surface during actuation movement of the plunger such that axial movement of the plunger relative to the housing causes relative rotational movement of the cam member and limits the forward velocity of the plunger movement.

Abstract: The present disclosure relates to a system and method for determining a basal rate adjustment based on risk associated with a glucose state of a person with diabetes. A method may include detecting a glucose state of the person based on a received glucose measurement signal and determining a current risk metric associated with the detected glucose state. The method may include identifying a reference glucose state and a reference risk metric associated with the reference glucose state, and calculating an adjustment to a basal rate of a therapy delivery device based on the current risk metric associated with the detected glucose state and the reference risk metric associated with the reference glucose level.

Abstract: A flexible polymeric tube comprising: an outer tubular wall layer comprised of a thermoplastic propylene-based elastomer (PBE) material, and, an innermost tubular layer comprised of a thermoplastic ethylene-based olefinic material.

Abstract: A connector includes: a male connector portion; a first female connector portion; and a second female connector portion. The connector defines a flow path therein. The male connector portion is shaped to be connectable to a medical device female connector portion that is equal in shape to the first female connector portion. The male connector portion is shaped to not be connectable to a medical device female connector portion that is equal in shape to the second female connector portion.

Abstract: Provided is a precision variable flow rate infusion system and method for delivering a liquid from a reservoir having an initial potential outflow rate to a patient. The system includes at least a first flexible flow rate tubing having a pre-defined flow rate selected at a maximum dosage flow rate for the liquid from the reservoir, the pre-defined flow rate being less than the initial potential outflow rate of the reservoir. Also provided is an adjustable flow rate controller having an inlet and an outlet, at least one internal fluid pathway there between and a fluid pathway modifier structured and arranged to modify the internal fluid pathway from the inlet to the outlet from a closed pathway to a maximum flow pathway with a plurality of different flow rate pathways there between.

Abstract: A rotatable drive mechanism for a drug delivery device may include a lead screw having a distal end, a proximal end, and external threads, a bearing, and a ball screw driver having a threaded aperture wherein the threaded aperture is configured to rotatably engage with the external threads of the lead screw. The mechanism may further include a biasing device disposed between the bearing and the ball screw driver generating an axial drive force, and an activation device configured to release the biasing device and allowing the biasing device to expand from a compressed position to an extended position through which the axial drive force of the biasing device causes the ball screw driver to axially move toward the distal end of the lead screw and rotate the lead screw such that a threaded engagement between the lead screw and the ball screw driver bears the axial drive force.

Abstract: A syringe needle shield that includes a first part and a second part. The first part is connected to the second part by a pivotable first connection portion. The second part is pivotable on the first connection portion toward the first part, and a needle hub is clamped between the first and second parts. The first and second parts are securely connected to each other by the first snapping portion which cannot be unlocked from each other. The first part is connected to a needle shield by a flexible plate. The shield receives a push force from its back so as to move from a first position to a second position. When the shield is located at the second position, a restriction portion is fixedly engaged with an engaging portion.

Abstract: An attachment device for securing an elongated element on the body of a patient is provided which includes a retaining support for retaining the elongated element, including at least one lower wall and an adhesive strip bearing the retaining support, and intended to be applied on the skin of the patient, the adhesive strip defining at least one region of the attachment device shifted with respect to the lower wall. A region of the attachment device located under the lower wall along an axis for inserting the elongated element into the retaining support is intended to be non-adherent to the skin of the patient. The retaining support comprises a clasping flap able to be maneuvered with respect to the lower wall between an open position and a clasping position of the elongated element. The elongated element is intended to be maintained between the lower wall and the clasping flap.