Patents Examined by Navin Natnithithadha
  • Patent number: 10905899
    Abstract: The invention provides a two-step tapered applicator, which can be used to deliver high-dose-rate vaginal brachytherapy to a female patient's vagina post-hysterectomy. In certain embodiments, once inserted through the female patient's vaginal opening (or introitus), the applicator of the invention causes less physical discomfort to the female patient than currently available applicators. In other embodiments, the applicator is used in a female patient whose vaginal apex is larger in diameter than her vaginal introitus.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: February 2, 2021
    Assignee: Yale University
    Inventors: Amandeep Mahal, James Yu, Shari Damast, Rajwant Mahal
  • Patent number: 10905894
    Abstract: A pain relief device is provided. The pain relief device includes: (i) a body portion including a contact region configured for contacting a subject; and (ii) a monopolar transmitter including a single electrical pole for providing an electrical signal to the body portion for treatment of the subject.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: February 2, 2021
    Assignee: Prezacor, Inc.
    Inventor: Gary Karpf
  • Patent number: 10905377
    Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: February 2, 2021
    Assignee: DexCom, Inc.
    Inventors: John Michael Gray, Jennifer Blackwell, Paul V. Neale, Justen Deering England, Andrew Joncich, Cameron Brock, Peter C. Simpson, Thomas Metzmaker, Neel Narayan Shah, Mark Douglas Kempkey, Patrick John Castagna, Warren Terry, Jason Halac, Christian Michael Andre George, Daniel E. Apacible, John Charles Barry, Maria Noel Brown Wells, Kenneth Pirondini, Andrew Michael Reinhardt, Jason C. Wong, Remy E. Gagnon, David DeRenzy, Randall Scott Koplin, Alan Baldwin, Young Woo Lee, David A. Keller, Louise Emma van den Heuvel, Carol Wood Sutherland
  • Patent number: 10905363
    Abstract: The present invention relates to a point-of-care (POC) diagnostic device adaptable to environmental changes and a control method thereof. The POC diagnostic device includes a measurement unit configured to perform a POC diagnosis, an information acquisition unit configured to acquire environmental information of the POC diagnostic device, and a control unit configured to predict a temperature of the measurement unit on the basis of the environmental information acquired by means of the information acquisition unit and correct a measurement value of the measurement unit or control the POC diagnostic device on the basis of the predicted temperature of the measurement unit.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: February 2, 2021
    Assignee: Osang Healthcare Co., Ltd.
    Inventor: Keun Young Kim
  • Patent number: 10898115
    Abstract: Systems for applying a transcutaneous monitor to a person can include a telescoping assembly, a sensor, and a base with adhesive to couple the sensor to skin. The sensor can be located within the telescoping assembly while the base protrudes from a distal end of the system. The system can be configured to couple the sensor to the base by compressing the telescoping assembly.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: January 26, 2021
    Assignee: DexCom, Inc.
    Inventors: Jason Halac, John Michael Gray, Neal Davis Johnston, Justen Deering England, Peter C. Simpson, Paul V. Neale, Jennifer Blackwell, Maria Noel Brown Wells, Kenneth Pirondini, Andrew Michael Reinhardt, Mark Douglas Kempkey
  • Patent number: 10898118
    Abstract: A needle assembly. The needle assembly enabling the analysis of fluid trapped in a flashback chamber after an insertion needle has been inserted into a patient's vein.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: January 26, 2021
    Assignee: Smiths Medical ASD, Inc.
    Inventors: David Goral, Harsh Chheda, Jay Breindel, Gursel Akcay, James Muskatello, David Justmann
  • Patent number: 10898114
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: January 26, 2021
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, James H. Brauker, Paul V. Goode, Jr., Aarthi Mahalingam, Jack Pryor
  • Patent number: 10898106
    Abstract: An implantable sensor configured to be inserted in an intramedullary canal can include a primary insert, a secondary insert, and an antenna. The primary insert can include a distal end, a proximal end opposite the distal end, and a central bore that can extend from an opening in the distal end towards the proximal end. A secondary insert can be receivable within the central bore through the opening. The secondary insert can include a body and a sensor module. The body can be removably engageable with an inside surface of the central bore. The sensor module can be disposable within the body and can be configured to produce a sensor signal as a function of a first sensed parameter indicative of infection. The antenna can be disposed in the central bore. The antenna can be configured to transmit a wireless signal as a function of the sensor signal.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: January 26, 2021
    Assignee: Biomet Manufacturing, LLC
    Inventors: Hilbrandus H. Bodewes, Mohammed Imran Khan, Daniel László-Deli, Max Hoeboer, Lisa Abdel Alim-van den Berg, Siemon Van Opstal, Bonita Koperdraat, Bart Krijgsman, Jurrit Heerink
  • Patent number: 10898087
    Abstract: An apparatus to detect a heart rate of a user includes a motion detection circuit configured to generate a motion status signal indicative of a motion status of the user. The apparatus also comprises a filter circuit coupled to the motion detection circuit that is configured to generate a filter circuit output signal based on dynamically variable. The coefficients are dependent on the motion status signal and a first signal received by the filter circuit. The apparatus also comprises a combination circuit coupled to the filter circuit and configured to receive a second signal indicative of the ambient light, the motion of the user, and non-ambient light reflected from the user. The combination circuit is configured to determine a difference between the second signal and the filter circuit output signal to generate a combination circuit output signal.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: January 26, 2021
    Assignee: TEXAS INSTRUMENTS INCORPORATED
    Inventors: Sarma Sundareswara Gunturi, Jaiganesh Balakrishnan
  • Patent number: 10893845
    Abstract: A wheezing detection apparatus includes a breathing sound detection unit that detects a breathing sound of a measurement subject and acquires a breathing sound signal in a time series expressing the breathing sound. The wheezing detection apparatus includes a determination processing unit that, in each pre-determined processing unit period, converts the breathing sound signal into a frequency space to acquire a frequency spectrum of the breathing sound, and based on a height and a width of a peak in the frequency spectrum, determines whether or not the peak indicates wheezing.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: January 19, 2021
    Assignee: OMRON HEALTHCARE CO., LTD.
    Inventor: Kei Asai
  • Patent number: 10888419
    Abstract: A device prepares leaflets for cardiovascular valve reconstruction from a pericardial tissue sheet harvested from a patient. A cutting tool is adapted to cut a predetermined pattern having a selected leaflet size. The device is continuously adjustable using a plurality of slidable blade segments forming a closed periphery. Radially-slidable links are slidably attached to respective blade segments. An adjustment disc is coupled to the links, wherein rotation of the adjustment disc varies a radial position of the links to modify an overlapping of the blade segments in order to select a corresponding size of the closed periphery.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: January 12, 2021
    Assignee: Terumo Cardiovascular Systems Corporation
    Inventors: Takeshi Tsubouchi, Randal J. Kadykowski
  • Patent number: 10888241
    Abstract: Apparatus, system, and computer readable media determine the probability of visual recognition of an image by a subject using electroencephalography (EEG) corresponding to a Visual Evoked Potential (VEP). The apparatus comprises means for presenting a series of visual stimuli corresponding to said image to evoke EEG signals. The visual stimuli of the image are presented in an orientation sequence based on a timing cycle. At least one prism is provided for placement in front of the series of visual stimuli corresponding to said image. The EEG signals evoked in response to said visual stimuli and said prism placed in front of said visual stimuli are recorded and processed by a processor. VEP is generated corresponding to the presence of a shift and thereby provides object statistic reliability of the visual recognition of the image by the subject.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: January 12, 2021
    Inventor: Ronald Siwoff
  • Patent number: 10888281
    Abstract: An apparatus for early detection of sepsis in a host is disclosed. The apparatus includes a first sensor to directly measure a glucose level, a second sensor to directly measure a lactate level and a third sensor to directly measure a tissue oxygen level. The first sensor, the second sensor, and the third sensor all being inserted at a single point of entry in a subcutaneous space of the host such that a predetermined correlation between the glucose level, lactate level, and tissue oxygen level signals conditions related to sepsis.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: January 12, 2021
    Assignee: PercuSense, Inc.
    Inventors: Rajiv Shah, Bradley Liang, Bahar Sutorius, Katherine Wolfe, Ellen Messer, Shaun Pendo
  • Patent number: 10874333
    Abstract: Systems and methods are presented for the diagnosis of middle ear pathological conditions based on spectral signatures. Preferred embodiments provide for detection of one or more analytes from the tympanic membrane. Devices use spectral measurements including spectral imaging to non-invasively identify middle ear pathological conditions including cholesteatoma and acute otitis media by providing real-time information of differentially expressed molecules. Devices and methods can also be used to non-invasively detect and quantify blood analytes from the tympanic membrane.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: December 29, 2020
    Assignees: Massachusetts Institute of Technology, Connecticut Children's Medical Center
    Inventors: Rishikesh Pandey, Nicolas Spegazzini, Luis H. Galindo, Ramachandra Dasari, Tulio Alberto Valdez
  • Patent number: 10874833
    Abstract: A cradle and methods of using embodiments of the cradle are described. The cradle has a proximal side and a distal side, where the proximal side has a skin attachment member for releasable attachment to a patient's skin. The distal side includes a device attachment member configured to attach an initially separate medical device. The cradle comprises an electronically controlled optical indication device, the electronically controlled optical indication device being configured to provide optical indications to the patient when the cradle is attached to the patient's skin.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: December 29, 2020
    Assignee: ROCHE DIABETES CARE, INC.
    Inventor: Illai J Gescheit
  • Patent number: 10869614
    Abstract: A gas concentration monitoring system (100, 600) may include a processor (110, 610) configured to detect a concentration of a selected gas in a sample gas flow obtained from a physical interface (107) to a patient (101); form a dataset including a plurality of data points, each data point corresponding to the detected concentration of the selected gas within the sample gas flow during a sampling time; group the data points according to a frequency of occurrence of the data points within the sampling time; and/or determine at least one of a signal confidence and signal quality based on relative characteristics between the groups of data points.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: December 22, 2020
    Assignee: Koninklijke Philips N.V.
    Inventors: Joseph Allen Orr, Lara Marie Brewer
  • Patent number: 10863935
    Abstract: Apparatus for optical tissue detection and discrimination between a tissue of a user and non-tissue materials and method of optical tissue detection and discrimination between a tissue of a user and non-tissue materials are provided. The apparatus for optical tissue detection includes one or more of light sources. The apparatus can further include at least one photodetector. A processor can be operable to determine whether the detected light is from a tissue of a user.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: December 15, 2020
    Assignee: Happy Health, Inc.
    Inventors: Paulo E. Xavier Da Silveira, Nithin O. Rajan, Dustin M. Freckleton
  • Patent number: 10864104
    Abstract: Method of using a shape-formable apparatus. A shape-formable apparatus can include an envelope defining a chamber, a port positioned to fluidly couple the chamber with ambience, and at least two locking sheets positioned in the chamber in an at least partially overlapping configuration. Each locking sheet can include a major surface, and at least a portion of each locking sheet can be patterned to include solid regions and open regions, the solid regions being movable with respect to one another within the major surface. The method can include providing the shape-formable apparatus in a first state; forming the apparatus into a desired shape; and reducing the pressure in the chamber to change the apparatus from the first state to a second state in which the apparatus is substantially less formable than in the first state.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: December 15, 2020
    Assignee: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: Thomas R. Corrigan, Marc A. Egeland, Alan R. Dombrowski
  • Patent number: 10863923
    Abstract: Spirometer, mouthpiece tube and inspection method thereof. The spirometer includes at least the mouthpiece tube and an ultrasound detector configured to detect the ultrasound generated by the gas flowing through the mouthpiece tube, wherein the mouthpiece tube has a shell having an opened end, a closed or opened end, and an ultrasonic generator configured to be inserted into different portions of the shell in different situations. Therefore, by inserting the ultrasonic generator into different portions of the shell during expiration and inspiration, the gas flow during expiration and inspiration may be converted into the ultrasonic signal and then maybe detected and analyzed.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: December 15, 2020
    Inventors: Chia-Hung Chen, Hsiao-Pao Yen, Chia-Chi Su, Liang-Lin Yen
  • Patent number: 10856785
    Abstract: Methods and Devices to monitor the level of at least one analyte are provided.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: December 8, 2020
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Marc Barry Taub, Jolyon Robert Bugler, Thomas A. Peyser