Abstract: An integrated guidewire includes a wire and a flexible tube. The wire is sized and shaped to move in an anatomical material transportation system of a patient. The flexible tube is sized and shaped to move in the anatomical material transportation system, having proximal and distal ends, the proximal-end is coupled to a device external to the patient, the flexible tube is configured to transfer fluids between the distal-end and the device, and the wire and the flexible tube are intertwined with respect to one another.

Abstract: An administration assembly for a medicament delivery device is presented having a plunger rod, a plunger rod holder and an activation sleeve configured to receive a portion of the plunger rod holder. The triggering member is configured to move the activation sleeve from a first position to a second position relative to the plunger rod holder. The plunger rod is configured to be axially locked relative to the plunger rod holder when the activation sleeve is in the first position. The plunger rod is released from being axially locked when the activation sleeve is moved towards the second position.

Abstract: Disclosed is an injection device for delivering a medicament from a syringe contained within a housing, the device being configured to move the syringe through the housing to cause insertion of a needle of the syringe into a user's skin and move a syringe bung through a syringe body, delivering medicament through the needle. The device includes: a plunger engaging the bung; a sleeve around the plunger; an insertion spring biasing the sleeve to the housing; and a delivery spring biasing the plunger to the sleeve. A release mechanism releases the sleeve from the housing to commence insertion and release the plunger from the sleeve, following insertion, delivering medicament. A velocity regulator regulates the plunger upon release and disengages during delivery, and includes a screw thread associated with the sleeve or plunger and one or more thread engaging members formed on the other of the sleeve and the plunger.

Abstract: Disclosed is a system for administrating fluids to a patient, such as an infant. The system comprises a container that defines a drip chamber, a source of nutritive fluid fluidically communicating with the drip chamber, and a tube connecting the drip chamber to the gastric cavity of a patient, the chamber including a membrane that is gas-permeable but that is resistant to fluid passage. The system allows fluids to be introduced to the patient and for gastric gases to be released while they are resistant to the leak and spillage.

Abstract: A catheter assembly includes a catheter and an inner needle inserted through the catheter. The catheter has a catheter body and a flexible portion that is provided at a distal portion of the catheter body, includes a most distal portion of the catheter, and is more flexible than the catheter body.

Abstract: Injection device comprising a housing having an insertion opening at its distal end, a syringe carrier arranged within said housing, an actuation sleeve that is slidably arranged in the housing, first and second energy accumulating members, a plunger holder that is operationally associated with the first energy accumulating member and the syringe carrier, and a plunger rod that is slidably arranged in relation to plunger holder and to the syringe carrier, the plunger rod being operationally associated with the second energy accumulating member.

Abstract: An injection device for receiving a syringe therein and for delivering a dose of medicament from the syringe, the injection device including: a driver mechanism retainable in a primed state and releasable from the primed state for driving one or more features of the injection device forwards, a trigger mechanism including a ramped surface engaged with the driver mechanism to retain the driver mechanism in the primed state, the trigger mechanism being configured on actuation thereof to withdraw the ramped surface from engagement with the driver mechanism for release thereof.

Abstract: A catheter is provided that includes a catheter body, a catheter hub, and a securing member disposed in the catheter hub to clamp the catheter between the securing member and the catheter hub. The securing member has an outer peripheral surface making contact with and stretching an inner peripheral surface of the catheter body. The catheter includes a recessed relief portion into which a thickness of the catheter body is inserted, the relief portion being partially provided circumferentially in an inner peripheral surface of the catheter hub.

Abstract: The invention relates to an implantable device suitable for being fixed in a fixation position to a wall of a patient's stomach, the implantable device being accommodated in the stomach when the implantable device is in the fixation position, the implantable device being characterised in that it comprises a reserve of an active substance and an injector suitable for administering the active substance to the patient.

Abstract: An apparatus includes a body, a cannula, a conduit, and a magnetic element. The cannula extends distally from the body. The cannula is flexible and has a distal end. The cannula defines a lumen distally terminating at the distal end. The cannula is sized and configured to pass between a sclera layer and a choroid layer in a human eye. The conduit is in fluid communication with the lumen. The magnetic element is positioned in the body.

Abstract: A patency checking system, may include a fluid path to be coupled to an intravenous (IV) device at a distal end of the fluid path; a patency port formed along a length of the fluid path; and a plunger fluidically coupled to the fluid path at the patency port to selectively draw blood into the fluid path to confirm patency of the fluid path.

Abstract: An injection device (1) for the delivery of medicament has an indicator (50) for providing an end of dose indication. The device comprises a housing (10), an extendable plunger (40), an actuation mechanism (30), a trigger arrangement (15), and an indicator (50). The extendable plunger (40) comprises a leading portion (42) and a trailing portion (48) configured to allow the plunger (40) to extend from an initial length to a maximum extended length, the plunger portions ((42),48) being slidably mounted within the housing (10). The actuation mechanism (30) is configured to move the leading portion (42) of the plunger (40) forwardly relative to a syringe (20) so as to express medicament from the syringe (20). The trigger arrangement (15) is moveable in use to release the actuation mechanism (30).

Abstract: A medicament delivery device (100; 300; 400) comprises a chassis (124), a drive element (166) for driving a stopper (22) to expel the medicament through a cannula (144). A carrier (126) is arranged for movement with respect to the chassis (124). Insertion means (130, 202) biases the carrier (126) in an insertion direction. A control part (132) is biased for rotation with respect to the carrier (126). A locking element (176) prevents rotation of the control part (132) in an initial state. The locking element (176) is coupled to the drive element (166) such that the control part (132) is released for rotation when the drive element (166) reaches an activation position during a delivery stroke. Rotation of the control part (132) through a predetermined angle causes decoupling of the insertion means (130, 202) from the carrier (126) to allow movement of the carrier (126) in a retraction direction after the end of the delivery stroke.

Abstract: A medicament delivery device is presented having a housing configured to accommodate a medicament container filled with medicament, a drive unit comprising a plunger rod operable to act on the medicament container, a mechanical activation mechanism configured to interact with the drive unit, where the mechanical activation mechanism is movable between certain predetermined states when interacting with the drive unit, a recording unit capable of recording status changes of the medicament delivery device including the status of the mechanical activation mechanism, and detection elements operably connected to the recording unit and positioned such as to detect when the activation mechanism has been moved between certain predetermined states.

Abstract: An automatic fluid injection device having a body fastened to a support. The body containing one or more fluid reservoirs, each containing an injection piston; a needle assembly including an injection needle; and an injection mechanism. The needle assembly including an injection needle and an insertion actuator made of a shape memory alloy. The needle assembly having a retraction ring; a needle support; an insertion ring; a retraction spring; an actuator ring; and an insertion spring. The insertion spring and the retraction spring retained, at rest, in their compressed state, activation of the actuator by heating to about 50% of the available contraction causing the needle support to be released, and activation of the actuator by heating to reach 100% of the available contraction causing the insertion ring and the assembly formed of the needle support and of the injection needle to be released.

Abstract: A blood sugar regulation system including: a blood sugar sensor; an insulin injection device; and a processing and control unit predicting the future evolution of the blood sugar based on a physiological model and accordingly controlling the insulin injection device, wherein the processing and control unit is capable of: a) implementing a calibration of the model by taking into account a history of the measured blood sugar; b) at the end of the calibration step, determining whether the model is satisfactory or not based on at least one numerical indicator representative of the error between the blood sugar estimated based on the model and the real blood sugar measured by the sensor; and c) if the quality of the model is not satisfactory, controlling the insulin injection device without taking into account the predictions made from the model.

Abstract: An auto-retractable blood collection needle, including: a needle holder including a first tube, a second tube and a holder tail; a needle in stalled in the first tube; a built-in sliding sleeve which is elongated and through and has a C-shaped cross section; a needle shield which is hollow and elongated; and a spring sheathed on the first tube. The second tube is installed in the built-in sliding sleeve and is capable of sliding back and forth. The built-in sliding sleeve is installed in the needle shield and is capable of sliding back and forth. A locking mechanism is formed by the holder tail and the needle shield. When the holder tail is unlocked from the needle shield, a force of the spring pushes the second tube to slide backward, and then the built-in sliding sleeve is driven to slide rearward to lock with the needle shield.

Abstract: An activation assembly for a medicament delivery device is presented having a delivery member cover provided with legs and configured to be biased in a proximal direction, a movable sleeve configured to be received between the legs, and an activation sleeve configured to be biased in the proximal direction, wherein the delivery member cover is configured to be moved in an axial direction between a first position and a second position, wherein movement of the delivery member cover from the first position to the second position causes movement of the movable sleeve from a first movable sleeve position to a second movable sleeve position. The delivery member cover axially displaces the activation sleeve in a distal direction when the delivery member cover moves towards the second position, thereby causing a first actuation of a sensor.

Abstract: A catheter assembly is disclosed, which includes a catheter, a catheter hub, a guide wire, and a guide wire hub. The guide wire has a guide wire rigidity changing portion that gradually decreases in rigidity from a proximal side toward a distal side, and the catheter has a catheter rigidity changing portion that gradually decreases in rigidity from a proximal side toward a distal side. In the catheter assembly, the catheter hub and the guide wire hub are connected to each other in a state where the distal side of the guide wire is exposed from a distal end of a lumen of a shaft portion and a guide wire rigidity changing point and a catheter rigidity changing point are aligned with each other in an axial direction.

Abstract: The technical objective of the present disclosure is to provide a steerable catheter enabling a lumen tip to approach an affected area only with an endoscope inserted together, without the aid of a C-type gantry based tomography apparatus. To this end, the steerable catheter according to the present disclosure includes: a housing; a lumen shaft; upper left, lower left, upper right and lower right wire parts; upper left, lower left, upper right and lower right stoppers; and a steering part for upwardly steering the terminal end of the lumen shaft by pulling the upper left and upper right wire parts, downwardly steering the terminal end of the lumen shaft by pulling the lower left and lower right wire parts, leftwardly steering the terminal end of the lumen shaft by pulling the upper left or lower left wire part, and rightwardly steering the terminal end of the lumen shaft by pulling the upper right or lower right wire part.