Abstract: A protective cap 2 is engaged with a latch 10 of a diluent container 5 so as to fix the diluent container 5 at a liquid holding position of a diluent container containing section 11. The engagement is released when the protective cap 2 is set to an open position against the engagement so as to expose an inlet 13. When the protective cap 2 is shifted from the open position to a closed position, the protective cap 2 pushes the diluent container 5 into a liquid discharge position. Thus, it is possible to preserve a diluent for a long period of time and to easily open the diluent container 5 without having to complicate the structure of an analysis apparatus.
Abstract: An apparatus, system and method for mixing and dispensing dental impression materials is described. A dental impression material mixing machine comprises a water dispenser fluidly coupled to a hollow mixing axle, the mixing axle extending through a pulley, wherein an inner circumference of the hollow mixing axle forms a water conduit and an outer circumference of the hollow mixing axle forms a hub connector, a closeable valve inserted at a water entrance to the water conduit and electronically coupled to a water pump, an electronically commutated motor rotateably coupled to the pulley, wherein the hub connector receives a tubular rotatable hub of a disposable mixing vessel comprising dry dental impression powder, and wherein water is dispensed from the water dispenser into the disposable mixing vessel through the water conduit and hub orifice.
Abstract: A protective cap 2 is engaged with a latch 10 of a diluent container 5 so as to fix the diluent container 5 at a liquid holding position of a diluent container containing section 11. The engagement is released when the protective cap 2 is set to an open position against the engagement so as to expose an inlet 13. When the protective cap 2 is shifted from the open position to a closed position, the protective cap 2 pushes the diluent container 5 into a liquid discharge position. Thus, it is possible to preserve a diluent for a long period of time and to easily open the diluent container 5 without having to complicate the structure of an analysis apparatus.
Abstract: The present invention provides a processing station for automatically processing a biological sample, a system for automated real-time inventory control of consumables within a biological sample handling or assay instrument, a high throughput random access automated instrument for processing biological samples, an automated instrument for processing or analysis of a sample, and processes for automated mucoid detection and elimination. Methods of using the disclosed instruments, mucoid detection processes, and systems to process and/or analyze samples are also disclosed.
Type:
Grant
Filed:
September 10, 2012
Date of Patent:
May 10, 2016
Assignee:
GEN-PROBE INCORPORATED
Inventors:
Rolf Silbert, David Opalsky, David Aaron Buse, Robert J. Rosati, Olev Tammer
Abstract: An apparatus for classifying a liquid patient sample includes at least one sample container having a quantity of a sample that is aggressively acted upon so as to create a flow field. A measurement mechanism includes at least one low angle light emitter aligned with a measurement window of the at least one sample container and a detector oppositely disposed relative to the measurement window. Measurement of the scattered light detects particle characteristics of a moving flow field from the sample to determine, for example, the amount of agglutination of the sample so as to perform blood typing or other classifications without spatial separation.
Type:
Grant
Filed:
May 13, 2010
Date of Patent:
April 12, 2016
Assignee:
Ortho-Clinical Diagnostics, Inc.
Inventors:
Merrit N. Jacobs, Michael W. Sundberg, Zhong Ding
Abstract: According to one embodiment, a measuring system using an optical waveguide is provided. The measuring system has an optical waveguide, magnetic fine particles, a magnetic field applying unit, a light source and a light receiving element. The optical waveguide has a sensing area to which first substances having a property of specifically bonding to subject substances to be measured are fixed. Second substances having a property of specifically bonding to the subject substances are fixed to the magnetic fine particle. The magnetic field applying unit generates a magnetic field for moving the magnetic fine particles. The light source inputs a light into the optical waveguide. The light receiving element receives the light output from the optical waveguide.
Abstract: Provided is an apparatus having a beam geometry changing device that changes the beam geometry of excitation light, and a control device that controls the beam geometry changing device, with favorable precision, which the apparatus performs a resonance angle scan and to detect a target material.
Abstract: A device for the transport of a placenta and a stand for the collection of stem cells from the placenta. The placental transport device comprising a cylindrical top portion and a cylindrical bottom portion together defining a placental storage region, with a hinge coupling the portions such that the placenta is enclosed inside the placental storage region when the cylindrical top and bottom portions are in a closed configuration. The stand comprising a base with a recess adapted to hold a placenta during stem cell collection solution loading, an upright back support, and an upper platform with a recess adapted to hold the placenta during collection of stem cells.
Abstract: A sample rack handling unit comprising an onload section for loading sample racks holding a sample container is presented. The onload section comprises an onload edge and a receiving area with an onload rail longitudinally on the receiving area parallel to the onload edge. The onload rail engages a recess on the rack bottom such that the rack longitudinally slides on the receiving area along the onload rail when the rack is engaged. The onload rail has a base portion and a protrusion extending from the base portion. The protrusion faces the onload edge and the base portion comprises an inclined onload rail side opposite the onload edge such that the recess engages the onload rail when the rack is loaded on the receiving area from the onload edge transversely to the onload rail and the recess disengages the onload rail by sliding the rack towards the onload edge.
Abstract: An electrically pumped light emitting device emits a light when powered by a power source. The light emitting device includes a first electrode, a second electrode including an outer surface, and at least one active organic semiconductor disposed between the first and second electrodes. The device also includes a dye adjacent the outer surface of the second electrode such that the second electrode is disposed between the dye and the active organic semiconductor. A voltage applied by the power source across the first and second electrodes causes energy to couple from decaying dipoles into surface plasmon polariton modes, which then evanescently couple to the dye to cause the light to be emitted.
Type:
Grant
Filed:
November 24, 2010
Date of Patent:
August 25, 2015
Assignee:
The Regents of The University of Michigan
Inventors:
Kwang Hyup An, Max Shtein, Kevin P. Pipe
Abstract: An apparatus, system and method for mixing and dispensing dental impression materials is described. A dental impression material mixing machine comprises a water dispenser fluidly coupled to a hollow mixing axle, the mixing axle extending through a pulley, wherein an inner circumference of the hollow mixing axle forms a water conduit and an outer circumference of the hollow mixing axle forms a hub connector, a closeable valve inserted at a water entrance to the water conduit and electronically coupled to a water pump, an electronically commutated motor rotateably coupled to the pulley, wherein the hub connector receives a tubular rotatable hub of a disposable mixing vessel comprising dry dental impression powder, and wherein water is dispensed from the water dispenser into the disposable mixing vessel through the water conduit and hub orifice.
Abstract: Wide-field fluorescent imaging on a mobile device having a camera is accomplished with a compact, light-weight and inexpensive optical components that are mechanically secured to the mobile device in a removable housing. Battery powered light-emitting diodes (LEDs) contained in the housing pump the sample of interest from the side using butt-coupling, where the pump light is guided within the sample holder to uniformly excite the specimen. The fluorescent emission from the sample is then imaged using an additional lens that is positioned adjacent to the existing lens of the mobile device. A color filter is sufficient to create the dark-field background required for fluorescent imaging, without the need for expensive thin-film interference filters.
Type:
Grant
Filed:
February 15, 2013
Date of Patent:
June 16, 2015
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Abstract: A chemical sensor using metal nano-particles and a method for manufacturing a chemical sensor using metal nano-particles are provided. The chemical sensor includes: metal nano-particles; single-ligand organic molecules (or a single molecule) that binds to the metal nano-particles by using a metal bonding functional group; a substrate bonding functional group formed at the metal nano-particles and the single-ligand organic molecules as bound to each other; a substrate; electrodes formed on the substrate and having an interdigitate (IDT) structure; and a substrate functional group formed on the substrate and positioned between the electrodes, wherein the substrate bonding functional group and the substrate functional group are covalently bonded.
Type:
Grant
Filed:
February 13, 2013
Date of Patent:
May 19, 2015
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Myung Lae Lee, Young Jun Kim, Sung Hae Jung, Ho Jun Ryu, Jong Moo Lee
Abstract: A method for sensing hydrogen includes the use of a transduction device with a sensing layer, and means for measuring a mass and/or conductivity change caused by an interaction of a gas with the sensing layer to provide a measure of an amount of hydrogen in the gas. The sensing layer includes polyaniline nanofiber material.
Type:
Grant
Filed:
August 2, 2011
Date of Patent:
May 19, 2015
Assignees:
The Aerospace Corporation, The Regents of the University of California
Inventors:
Shabnam Virji, Richard B. Kaner, Bruce H. Weiller
Abstract: This invention provides a cell made of polymers for spectra measurement while inhibiting a decrease in a molecular weight of resin caused by discharge treatment and having a stable hydrophilic modified surface. The hydrophilic resin cell is prepared by providing a polymeric resin cell between the two opposing electrodes, applying an electric field to a region between the above opposing electrodes under a nitrogen atmosphere with a pressure close to the atmospheric pressure to generate an electric discharge, and exposing the cell subjected to discharge treatment with a gas including oxygen.
Abstract: An adapter for use with a hand-held electronic device for use in detecting the optical properties of a sample. The adapter includes a backing plate having an integral surface that secures the adapter to the electronic device. The adapter also includes a sample housing having a sample holder and a cap. The sample holder is configured to receive the placement of a sample and/or a sample vessel. The backing plate includes an orifice that allows the passage of light from the sample to the detector of the electronic device. The backing plate may also include another orifice that allows for light emitted from an emitter of the electronic device to enter into the sample holder. The sample holder may also include reflective surfaces that direct light to/from the sample as well as filters that filter the wavelength of light sent to sample and/or detected by the detector.
Type:
Grant
Filed:
December 5, 2012
Date of Patent:
May 5, 2015
Assignee:
Promega Corporation
Inventors:
Rob Chumanov, Julia Krueger, Steve Krueger, Sydnor T. Withers, III
Abstract: An apparatus, system and method for mixing and dispensing dental impression materials is described. A dental impression material mixing machine comprises a water dispenser fluidly coupled to a hollow mixing axle, the mixing axle extending through a pulley, wherein an inner circumference of the hollow mixing axle forms a water conduit and an outer circumference of the hollow mixing axle forms a hub connector, a closeable valve inserted at a water entrance to the water conduit and electronically coupled to a water pump, an electronically commutated motor rotatably coupled to the pulley, wherein the hub connector receives a tubular rotatable hub of a disposable mixing vessel comprising dry dental impression powder, and wherein water is dispensed from the water dispenser into the disposable mixing vessel through the water conduit and hub orifice.
Abstract: A system for diagnostic testing may include a meter for performing a diagnostic test on a sample applied to a test media, the meter having a housing and an interface for receiving a signal representing coding information, and a container configured to contain test media compatible with the meter, the container having a coding element associated therewith. Additionally, the system may provide a mechanism for removing the meter from an interconnected test container and reattaching it to a new container using on-container coding methods that can recalibrate the meter for the new container of test strips.
Type:
Grant
Filed:
November 1, 2007
Date of Patent:
January 27, 2015
Assignee:
Nipro Diagnostics, Inc.
Inventors:
Gary T. Neel, Brent E. Modzelewski, George R. Rounds, Carlos Oti, Allan Javier Caban, Jeffrey Akins
Abstract: The present invention is directed to an assembly for use in detecting an analyte in a sample based on thin-film spectral interference. The assembly comprises a waveguide, a monolithic substrate optically coupled to the waveguide, and a thin-film layer directly bonded to the sensing side of the monolithic substrate. The refractive index of the monolithic substrate is higher than the refractive index of the transparent material of the thin-film layer. A spectral interference between the light reflected into the waveguide from a first reflecting surface and a second reflecting surface varies as analyte molecules in a sample bind to the analyte binding molecules coated on the thin-film layer.
Type:
Grant
Filed:
December 3, 2013
Date of Patent:
January 27, 2015
Assignee:
Access Medical Systems, Ltd.
Inventors:
Hong Tan, Yushan Tan, Erhua Cao, Ming Xia, Robert F. Zuk
Abstract: A sample analyzer is disclosed. The sample analyzer comprises: a reader for reading ID of a sample from a sample container; an aspirator that aspirates a sample in a sample container; an analyzing section that analyzes the aspirated sample; a manual input receiver for receiving a manual input of an ID of a sample; an start instruction receiver for receiving a start instruction to cause the aspirator to aspirate a sample; and a controller. When receiving the start instruction without receiving the manual input, the controller controls the reader to read an ID from a sample container and then controls the aspirator to aspirate the sample from the sample container. When receiving the start instruction after receiving the manual input, the controller controls the aspirator to aspirate a sample without reading of an ID of the sample.