Patents Examined by Nicole F Lavert
  • Patent number: 10780271
    Abstract: Technology for the transition of light and sound over long distances, e.g. TV and radio, has revolutionized society. On the contrary, the technology to perceive a smell remotely is in its infancy, and has severe limitations such as latency, residual and infidelity. A system and methods are disclosed to allow smells to be perceived remotely. It is based on the brain waves associated with the olfactory bulb.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: September 22, 2020
    Inventors: Lucas Mingzhi Zhou, Lin Zhou, Christopher Li
  • Patent number: 10773089
    Abstract: Delivery devices, systems, and methods for delivering implantable leadless pacing devices are disclosed. An example delivery device may include an intermediate tubular member and an inner tubular member slidably disposed within a lumen of the intermediate tubular member. A distal holding section may extend distally of a distal end of the intermediate tubular member and define a cavity therein for receiving an implantable leadless pacing device. The device may be configured to enable fluid flushing of the delivery device prior to use, to remove any air from within the device as well as providing the option of fluid flow during use of the delivery device.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: September 15, 2020
    Inventors: Brian Soltis, Benjamin J. Haasl, James P. Goodman, Vincent P. Hackenmueller
  • Patent number: 10773084
    Abstract: Systems and methods for stimulation of neurological tissue generate stimulation trains with temporal patterns of stimulation, in which the interval between electrical pulses (the inter-pulse intervals) changes or varies over time. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention provide a lower average frequency.
    Type: Grant
    Filed: February 20, 2017
    Date of Patent: September 15, 2020
    Assignee: Duke University
    Inventors: Warren M. Grill, David T. Brocker
  • Patent number: 10773002
    Abstract: A blood pump comprises a pump casing, a blood flow inlet and a blood flow outlet connected by a passage, and an impeller. The impeller comprises blades configured to convey blood from the blood flow inlet to the blood flow outlet, the impeller being supported in the pump casing by at least one contact-type bearing comprising a surface of the impeller facing a surface of the pump casing. At least one wash out channel extends through the impeller and is in fluid connection with the passage via a first opening and with the bearing via a second opening. The wash out channel is operatively associated with a secondary pump for pumping blood through the wash out channel towards the bearing. The secondary pump is formed at least partially by said at least one wash out channel extending through the impeller along a direction having at least one tangential directional component.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: September 15, 2020
    Inventors: Thorsten Siess, Walid Aboul-Hosn
  • Patent number: 10773074
    Abstract: In certain embodiments an electrode array for epidural stimulation of the spinal cord is provided where the array comprises a plurality of electrodes disposed on a flexible polymer substrate; said electrodes being electrically connected to one or more lead wires and/or connection points on an electrical connector; where the electrodes of said array are bonded to said polymer so that the electrodes can carry an electrical stimulation signal having a voltage, frequency, and current sufficient to provide epidural stimulation of a spinal cord and/or brain in vivo or in a physiological saline solution, without separation of all or a part of an electrode from the polymer substrate.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: September 15, 2020
    Assignee: The Regents of the University of California
    Inventors: Wentai Liu, Victor Reggie Edgerton, Chih-Wei Chang, Parag Gad
  • Patent number: 10758711
    Abstract: The present invention relates to a treatment kit comprising: a guide having a distal end and a proximal end; a position determination device for determining the position of the distal end of the guide in the body of a patient; and a catheter intended to be inserted into the body of the patient. The guide is graduated between its distal end and its proximal end, the graduations of the guide making it possible to measure a length of insertion of the guide into the body of the patient, and the catheter is adapted so as to be cut to a predetermined length that is determined based on the length of insertion.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: September 1, 2020
    Inventors: Laƫtitia Vin, Thomas Walter
  • Patent number: 10751537
    Abstract: An implant unit configured for implantation into a body of a subject is provided. The implant unit may include a flexible carrier unit including a central portion and two elongated arms extending from the central portion, an antenna, located on the central portion, configured to receive a signal, at least one pair of electrodes arranged on a first elongated arm of the two elongated arms. The at least one pair of electrodes may be adapted to modulate a first nerve. The elongated arms of the flexible carrier may be configured to form an open ended curvature around a muscle with the nerve to be stimulated within an arc of the curvature.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: August 25, 2020
    Assignee: Nyxoah SA
    Inventors: Adi Mashiach, Itzik Mashiach
  • Patent number: 10751528
    Abstract: Disclosed herein is an implantable electronic device for use with an implantable medical lead. The implantable electronic device includes a housing and a header connector assembly coupled to the housing and adapted to receive the proximal lead end of the implantable medical lead. The header connector assembly includes a connector assembly including a connector, a feedthru extending through the housing, and a conductor coupling the feedthru to the connector. The conductor includes a first conductor segment and a second conductor segment offset from the first conductor segment and each of the first conductor segment and the second conductor segment are resistance welded to the connector.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: August 25, 2020
    Assignee: Pacesetter, Inc.
    Inventors: Shichan Chiang, Evan Sheldon, Armando M. Cappa
  • Patent number: 10751525
    Abstract: Conductors within an implantable medical lead that carry stimulation signal signals are at least partially embedded within a lead body of the medical lead over at least a portion of the length of the conductors while being surrounded by a radio frequency (RF) shield. A space between the shield and the conductors is filled by the presence of the lead body material such that body fluids that infiltrate the lead over time cannot pool in the space between the shield and the conductors. The dielectric properties of the lead body are retained and the capacitive coupling between the shield and the conductors continues to be inhibited such that current induced on the shield is inhibited from being channeled onto the conductors. Heating at the electrodes of the medical lead is prevented from becoming excessive.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: August 25, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Jamu K. Alford, Spencer Fodness Bondhus, Michael Kalm, James M. Olsen, Brian T. Stolz, Richard T. Stone, Bryan D. Stem, John D. Welter
  • Patent number: 10751533
    Abstract: In various embodiments methods and devices are provided for regulating bladder function in a subject after a spinal cord and/or brain injury. In certain embodiments the methods comprise applying a pattern of electrical stimulation to the Lumbosacral spinal cord at a frequency and intensity sufficient to initiate micturition and/or to improve the amount of bladder emptying. In certain embodiments the electrical stimulation is at a frequency and intensity sufficient to improve the amount of bladder emptying (e.g., to provide at least 30% emptying or at least 40% emptying, or at least 50% emptying, or at least 60% emptying, or at least 70% emptying, or at least 80% emptying, or at least 90% emptying, or at least 95% emptying.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: August 25, 2020
    Assignee: The Regents of the University of California
    Inventors: Victor Reggie Edgerton, Parag Gad, Roland R. Roy, Yury P. Gerasimenko, Daniel C. Lu, Hui Zhong
  • Patent number: 10736565
    Abstract: Embodiments of the disclosed invention provide devices and methods to incorporate suspension-based, i.e., hydrogel-based and thixotropic compound-based, ion-selective electrodes and reference electrodes into a wearable sweat sensing device. Embodiments of this device are configured to monitor sweat electrolyte concentrations, trends, and ratios under demanding use conditions. The accompanying method includes use of the disclosed device to track fluid and electrolyte gain and loss in order to produce an electrolyte estimate, such as a sweat electrolyte concentration, a sweat electrolyte concentration trend, a sweat rate, or a concentration ratio between a plurality of electrolytes.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: August 11, 2020
    Assignee: Eccrine Systems, Inc.
    Inventors: Gavi Begtrup, Austin Morgan, Mikel Larson, Jacob A. Bertrand, Nicholas Bailey, Cory Newland, Robert Beech, Brian Hanley
  • Patent number: 10736604
    Abstract: Disclosed are systems and methods using ultrasound to predict if a patient's cardiac stroke volume will increase with a fluid bolus. Ultrasound measures are taken before administering a fluid bolus, including measurement of the left ventricular outflow tract velocity time integral (LVOT VTI), and venous measurements of the internal jugular vein. Data collected from such ultrasound scan is then used to predict the patient's cardiac volume response in the event that a fluid bolus is administered to that patient.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: August 11, 2020
    Assignee: University of Maryland, Baltimore
    Inventor: Sarah B. Murthi
  • Patent number: 10737095
    Abstract: Neurostimulator devices are described. An example neurostimulator device includes a stimulation assembly connectable to a plurality of electrodes, wherein the plurality of electrodes are configured to stimulate a spinal cord. The neurostimulator device also includes an interface and at least one processor configured to modify at least one complex stimulation pattern deliverable by the plurality of electrodes by integrating data from the interface and performing a machine learning algorithm on the at least one complex stimulation pattern.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: August 11, 2020
    Assignee: Californina Institute of Technology
    Inventors: Joel W. Burdick, Yu-Chong Tai, John F. Naber, Robert S. Keynton, Victor Reggie Edgerton, Roland R Roy, Yury Gerasimenko, Susan J. Harkema, Jonathan Hodes, Claudia A. Angeli, Mandheerej S. Nandra, Thomas Anthony Desautels, Steven L. Upchurch, Douglas J. Jackson, Nicholas A. Terrafranca, Jr., Yangsheng Chen
  • Patent number: 10737098
    Abstract: An ear-piece assembly includes (i) an antenna portion enclosing a transmitting antenna configured to send one or more input signals containing electrical energy to a passive implantable neural stimulator device such that the passive implantable neural stimulator generates one or more stimulation pulses suitable for stimulating a neural structure in the craniofacial region solely using the electrical energy in the input signals; and (ii) an enclosure coupled to the antenna portion, wherein enclosure is sized and shaped to be mounted on a helix portion of an ear such that, when worn by a patient, weight from the enclosure is distributed over the helix portion of the ear for the enclosure to rest thereon, wherein the enclosure includes (i) a controller module configured to provide the one or more input signals to the transmitting antenna, and (ii) a battery adapted to provide energy to the ear-piece assembly.
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: August 11, 2020
    Assignee: Stimwave Technologies Incorporated
    Inventors: Laura Tyler Perryman, Chad David Andresen, Graham Patrick Greene
  • Patent number: 10737102
    Abstract: An implantable medical device (IMD) may include a fixation module, and a device module that is configured to be releasably connected to the fixation module. The device module may have a proximal end and a distal end, and may include a power source and a controller that is operably coupled to the power source. The controller may be configured to sense cardiac electrical activity via two or more electrodes and/or deliver pacing pulses via two or more electrodes. The device module may include a first part of a releasable connector while the fixation module may include a second part of the releasable connector, wherein the first part of the releasable connector and the second part of the releasable connector cooperate to releasably connect the device module with the fixation module.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: August 11, 2020
    Inventors: Erin Kristen Webb, Bryan J. Swackhamer, Dana Sachs
  • Patent number: 10729341
    Abstract: A wearable system can include at least one cuff; nerve activity acquisition electrodes; nerve stimulation electrodes; circuitry operatively coupled to the nerve activity acquisition electrodes and to the nerve stimulation electrodes; and memory operatively coupled to the circuitry that stores nerve information.
    Type: Grant
    Filed: January 10, 2016
    Date of Patent: August 4, 2020
    Inventors: Wambui Nyabero, Lucas Nyabero
  • Patent number: 10729724
    Abstract: Nanosecond pulsed electric field (nsPEF) treatments of a tumor are adjusted based on a size and type of the tumor to stimulate an immune response against the tumor and other tumors in the subject. Calreticulin expression on tumor cells can be detected to confirm treatment. An immune response biomarker can be measured, and further nsPEF treatments can be performed if needed to stimulate or further stimulate the immune response. Cancers that have metastasized may be treated by directly treating a tumor that is most accessible. The treatment can be combined with CD47-blocking antibodies, doxorubicin, CTLA-4-blocking antibodies, and/or PD-1-blocking antibodies. Electrical characteristics of nsPEF treatments can be based on the size, type, and/or strength of tumors and/or a quantity of tumors in the subject.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: August 4, 2020
    Assignee: Pulse Biosciences, Inc.
    Inventors: Richard Lee Nuccitelli, Pamela S. Nuccitelli, Joanne Lum, Kaying Lui, Brian G. Athos, Mark P. Kreis, Zachary R. Mallon, Jon Berridge
  • Patent number: 10722305
    Abstract: An energy delivery probe and method of using the energy delivery probe to treat a patient is provided herein. The energy delivery probe has at least one probe body having a longitudinal axis and at least a first trocar and a second trocar. Each trocar comprises at least two electrodes that are electrically insulated from each other, and each electrode is independently selectively activatable. An insulative sleeve is positioned in a coaxially surrounding relationship to each of the first trocar and the second trocar. The probe also has a switching means for independently activating at least one electrode. The method involves independently and selectively activating the first and second electrodes to form an ablation zone, then repeating the ablation by delivering energy to a second set of electrodes, producing one or more overlapping ablation zone, and eliminating the need to reposition the ablation probes.
    Type: Grant
    Filed: May 21, 2018
    Date of Patent: July 28, 2020
    Assignee: AngioDynamics, Inc.
    Inventors: Kevin L. Moss, Robert M. Pearson
  • Patent number: 10722721
    Abstract: A pulse generator that includes a communications module is disclosed herein. The communication module includes a transceiver and an antenna circuit. The antenna circuit includes a first pathway having a capacitor and a second, parallel pathway including a capacitor, and a resistor, and a radiating element arranged in series. The antenna circuit is tuned to have a resonant frequency corresponding to a desired transmission frequency and a bandwidth corresponding to shifts in the resonant frequency arising from the implantation of the antenna.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: July 28, 2020
    Inventors: Rabih Nassif, Hisham Hasbini
  • Patent number: 10716934
    Abstract: Presented herein are techniques for the determination/selection of a set of electrodes for use in an electrically-stimulating auditory/hearing prosthesis. More specifically, an electrically-stimulating hearing prosthesis includes a plurality of electrodes implanted in a recipient. Based, at least in part on a recipient's subjective preferences, one or more of these electrodes may be deactivated. The remaining (i.e., non-deactivated) electrodes form a final electrode set that is subsequently used by the hearing prosthesis for subsequent hearing rehabilitation operations.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: July 21, 2020
    Inventor: Sean Lineaweaver