Abstract: Novel .beta.-diketonate complexes incorporating a tetrahydrofuran adduct, having the formula M(hfa).sub.2.nTHF wherein M is Mg or Zn and n is in the range of about 1-4 and, which offer high volatility and good chemical stability at vaporization temperatures, are described.

Abstract: A piperidine derivative of the formula: ##STR1## wherein R represents a hydrogen atom, a (C.sub.1-4)alkyl, hydroxy(C.sub.1-4)alkyl, (C.sub.1-4)alkoxycarbonyl or benzyl radical, or a benzyl radical carrying a substituent selected from halogen atoms and (C.sub.1-4)alkoxy radicals, or the phenethyl or 3-phenylpropyl radical, and X represents one or more hydrogen or halogen atoms or (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, trifluoromethyl or methylenedioxy radicals, or alternatively X forms with the phenyl nucleus a naphthyl radical, with the proviso that when R represents a hydrogen atom X is other than a hydrogen atom, are new compounds useful in therapy and, more particularly, as antidepressants.

Abstract: 2-[2-Hydroxy-4-(substituted)phenyl]piperidines and derivatives thereof of the formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof, wherein R.sub.1 is H, benzyl or certain acyl groups, R.sub.2 is H, certain alkyl, alkenyl, alkynyl, hydroxyalkyl, acyl or alkylsulfonyl groups; R.sub.3 is H.sub.2, O, ##STR2## and Z is (C.sub.1 -C.sub.13)alkylene or -(alk.sub.1).sub.m -O-(alk.sub.2).sub.n - where each of (alk.sub.1) and (alk.sub.2) is (C.sub.1 -C.sub.13)alkylene, provided that the number of carbon atoms in (alk.sub.1) plus (alk.sub.2) is not greater than 13; each of m and n is 0 or 1; and W is H, pyridyl or optionally substituted phenyl; their use as analgesic agents, intermediates therefor and processes for their preparation.

Abstract: The present invention relates to new benzoyl-phenyl-piperidine derivatives selected from the group consisting of:(i) 2-piperidinobenzophenones of the general formula: ##STR1## in which: R.sub.1, R.sub.2 and R.sub.3, which are identical or different, each represent an atom of hydrogen, a hydroxy group, CF.sub.3, a halogen, a lower alkyl group or a lower alkoxy group;R.sub.4 represents an atom of hydrogen, a halogen, an NO.sub.2 group, an NR'R" group [where R' and R", which are identical or different, represent an atom of hydrogen, a lower alkyl group or a CO.sub.2 R group (where R represents a lower alkyl group or a benzyl group)];R.sub.5 and R.sub.6, which are identical or different, each represent an atom of hydrogen, a C.sub.1 -C.sub.4 -alkyl group, an OH group, a phenyl group or a benzyl group; and(ii) acid addition salts thereof.The invention also relates to the method for preparing these new derivatives and to their use in therapeutics, particularly as immunostimulant and immunoadjuvant agents.

Abstract: In the process of preparing acetoxyhexenoic acids from butadiene, acetic acid and acetic anhydride, selectivity is improved by converting the acetoxyhexenoic acids to .gamma.-vinyl-.gamma.-butyrolactone before isolation. Copper and platinum are useful catalysts in the conversion.

Abstract: There are provided novel substituted phenyl (thiono)carbamates capable of effectively controlling broad-leaved annual weeds and annual weeds belonging to the families Gramineae and Cyperaceae such as wild Echinochloa species, monochoria, toothcup and umbrella plant, herbicidal compositions containing these (thiono)carbamates as active ingredient and a method of controlling weeds using these (thiono)carbamates. The (thiono)carbamates are substantially nonphytotoxic to useful crop plants such as the paddy rice plant.

Abstract: A process for the production of cycloalkane epoxides from cycloalkenes in the presence of a tungsten or zirconium containing catalyst, oxygen and a carboxylate ion source via air oxidation is described. For example, cobalt tungstate, nickel tungstate, silver tungstate and manganese tungstate are useful catalysts. Active zirconates are cerium zirconate, cadmium zirconate and lead zirconate. The reaction is conducted at a temperature in the range of 50.degree. to 150.degree. C. and a pressure of one atmosphere or greater. Cycloalkane epoxides are useful in the preparation of resins, plasticizers, etc.

Abstract: Compounds having blood-anticoagulant properties of the general molecular formula: ##STR1## in which Z represents a halogen atom, preferably a chlorine atom, and n is 0, 1 or 2 and R.sup.

Abstract: A process for the production of cycloalkane epoxides from cycloalkenes in the presence of an oxide catalyst, oxygen and a carboxylate ion source via air oxidation is described. The oxide catalyst may have as a cation boron, chromium, iron, nickel, copper, zinc or terbium or mixtures thereof. Combination catalysts such as ferric oxide/zinc oxide and nickel oxide/copper oxide/chromium oxide/boric oxide complexes are also found to be useful. The reaction is conducted at a temperature in the range of 50.degree. to 150.degree. C. and a pressure of one atmosphere or greater. Cycloalkane epoxides are useful in the preparation of resins, plasticizers, etc.

Abstract: The 1-acyloxy-6-hydroxy-IsoMB-530B lactones of the formula (I): ##STR1## wherein R.sup.1 represents a group of the formula ##STR2## wherein R.sup.2 is a C.sub.1 -C.sub.10 alkyl group.

Abstract: Novel 2-(hydroxyphenylamino)benzamides and oxidation products thereof, useful as inhibitors of lipoxygenase, are of the formulas ##STR1## wherein R is hydrogen, lower-alkyl, halo or lower-alkoxy; R' is hydrogen or lower-alkyl; R" is hydrogen, lower-alkyl or halo; and N.dbd.Z is amino or substituted amino. The compounds of Formula I are prepared by de-etherification of the corresponding alkyl or benzyl ethers; and the compounds of Formula II are prepared by oxidation of the compounds of Formula I where R' is hydrogen and OH is in the 4-position.

Abstract: The following process steps are shown: ##STR1## Intermediates I, II, and VI are new. End product IV is a known intermediate in the preparation of known pyrethroid-like cyclopropanecarboxylic acid ester insecticides.

Abstract: Fluorane compounds of the formula (1) ##STR1## in which each of R.sub.1 and R.sub.2 is an H atom or an alkyl.sub.C.sbsb.1.sub.-C.sbsb.12, cycloalkyl.sub.C.sbsb.5.sub.-C.sbsb.7, alkenyl.sub.C.sbsb.2.sub.-C.sbsb.4, phenyl, naphthyl or benzyl group and R.sub.1 and R.sub.2, together with the N atom, can be an optionally alkyl.sub.C.sbsb.1.sub.-C.sbsb.4 -substituted piperidine or morpholine radical, R.sub.3 represents an H atom or an alkyl.sub.C.sbsb.1.sub.-C.sbsb.12, cycloalkyl.sub.C.sbsb.5.sub.-C.sbsb.7, alkenyl.sub.C.sbsb.2.sub.-C.sbsb.4, phenyl, naphthyl, benzyl, acetyl, propionyl or benzoyl group, each of R.sub.4, R.sub.5, R.sub.6 and R.sub.7 denotes an alkyl.sub.C.sbsb.1.sub.-C.sbsb.4 group, R.sub.8 is an H atom or an alkyl.sub.C.sbsb.1.sub.-C.sbsb.4, benzyl, acetyl, propionyl or benzoyl group, each of Y.sub.1 and Y.sub.2 represents a hydrogen, fluorine, chlorine or bromine atom or an alkyl.sub.C.sbsb.1.sub.-C.sbsb.4, alkoxy.sub.C.sbsb.1.sub.-C.sbsb.4, nitro, optionally alkyl.sub.C.sbsb.1.sub.-C.sbsb.

Abstract: Novel aryloxymethylpyrrolidinols and piperidinols are provided of the formula: ##STR1## wherein R.sup.1 is hydrogen, loweralkyl and phenylloweralkyl; R.sup.2 is hydrogen, loweralkyl and acyl; R.sup.3 is phenyl, naphthyl, 4-indanyl and 5-indanyl; m is 2 or 3 and n is 1 or 2; and the pharmaceutically acceptable salts thereof, having antiarrhythmic, antidepressant and antihypertensive activity.

Abstract: The invention provides a process for the continuous manufacture of trioxan, optionally together with cyclic formals, from aqueous formaldehyde solutions in a circulation reactor with evaporator, the vapor/liquid mixture leaving the evaporator is fed in below the liquid level of the reaction mixture. The process of the invention allows to attain especially high space/time yields.

Abstract: Cultivation of a strain of the microorganism Pseudomonas cepacia SC 11,783, A.T.C.C. No. 39356 yields a novel antibiotic substance which is made up of two compounds, i.e., 5-[3-[3-(hepta-1,2-dien-4,6-diynyl)oxiran-2-yl]-3-hydroxy-1-propanyl]dihyd ro-2(3H)-furanone and 5-[[3-[3-(hepta-1,2-dien-4,6-diynyl)-2-oxiranyl]-2-oxiranyl]hydroxymethyl] dihydro-2(3H)-furanone.

Abstract: Dihydro-4,4-dimethylfuran-2,3-dione is prepared by oxidation of racemic dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone by a process in which the oxidation is carried out by gradually adding powdered calcium oxide to a solution of racemic dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone and chlorine in the inert organic solvent.

Abstract: New cyclic carbonic acid derivatives of the formula ##STR1## in which R denotes either --CH.sub.2 OH, R.sup.1 then representing an alkyl radical having 1 to 4 C atoms, or ##STR2## R.sup.1 and R.sup.2 then independently of one another representing methyl or ethyl, or ##STR3## R.sup.1 and R.sup.3 then each representing an alkyl radical having 1 to 4 C atoms,or in whichR and R.sup.1 together denote ##STR4## wherein A represents the group ##STR5## or oxygen, a process for their preparation, and their use as copolymerization components in the preparation of polycarbonates.

Abstract: Novel .beta.-diketonate complexes incorporating a tetrahydrofuran adduct, having the formula M(hfa).sub.2.nTHF wherein M is Mg or Zn and n is in the range of about 1-4 and, which offer high volatility and good chemical stability at vaporization temperatures, are described.

Abstract: 7-phenyl-7-phenoxymethyl-hexahydro-1,4-oxazepines of the formula I ##STR1## wherein R.sup.1 is hydrogen, chlorine or methoxy and R.sup.2 is hydrogen or methyl, and their salts with physiologically tolerated acids, and their preparation, are described. The substances are useful for treating disorders.