Abstract: Provided are compositions which may be used in agricultural applications. Also provided are methods of making and using the compositions. In embodiments, a plant fungicide or plant bactericide is provided comprising a nanostructured chemical compound, the chemical compound comprising a metal and a coordinating anion, wherein the nanostructured chemical compound is in the form of a plurality of planar, two-dimensional nanostructures.

Abstract: Provided herein are stable amlodipine liquid formulations. Also provided herein are methods of using amlodipine liquid formulations for the treatment of certain diseases including hypertension and Coronary Artery Disease (CAD).

Abstract: Apertured fibrous structures and more particularly apertured fibrous structures containing one or more fibrous elements, for example filaments, containing one or more fibrous element-forming materials and one or more active agents that are releasable from the fibrous element when exposed to conditions of intended use, and methods for making same.

Abstract: Biomedical devices for implantation with decreased pericapsular fibrotic overgrowth are disclosed. The device includes biocompatible materials and has specific characteristics that allow the device to elicit less of a fibrotic reaction after implantation than the same device lacking one or more of these characteristic that are present on the device. Biocompatible hydrogel capsules encapsulating mammalian cells having a diameter of greater than 1 mm, and optionally a cell free core, are disclosed which have reduced fibrotic overgrowth after implantation in a subject. Methods of treating a disease in a subject are also disclosed that involve administering a therapeutically effective amount of the disclosed encapsulated cells to the subject.

Abstract: A layered body comprising: a core region; at least one intermediate layer disposed around the core region; and an outer layer disposed around the at least one intermediate layer, wherein at least one of the at least one intermediate layers comprises a gas, the layered body having at least one dimension, measured across the body and through the core region, of 100 ?m or less.

Abstract: Preparation of high-performance antimicrobial agent based on ZnO/GODs-PEI composites. Nano ZnO is regarded as the effective antibacterial agents because of its distinctive photocatalytic properties. However, the fast recombination of photo-generated electrons and holes on the surface of ZnO seriously affects antibacterial activities. Therefore, numerous methods such as controlling the size and morphology of ZnO, doping metal and nonmetal ions, coupling semiconductor, constructing heterojunction and surface modification have been used to increase the activity of ZnO. The application aims to synthesize a stable low-dimensional ZnO/GQD aqueous with excellent dispersity and enhanced absorption to further improve its antibacterial activities. Hence, amphiphilic polyethylenimine-functionalized graphene quantum dots (GQD-PEI) was prepared firstly, which was then used to transfer ZnO NPs to water to obtain water-soluble ZnO/GODs-PEI composites.

Abstract: The invention provides medical devices comprising high-strength alloys which degrade over time in the body of a human or animal, at controlled degradation rates, without generating emboli and which have enhanced degradation due to the presence of a halogen component. In one embodiment the alloy is formed into a bone fixation device such as an anchor, screw, plate, support or rod. In another embodiment the alloy is formed into a tissue fastening device such as staple. In yet another embodiment, the alloy is formed into a dental implant or a stent.

Abstract: Porous calcium lactate metal-organic frameworks (MOFs) comprise non-toxic metal ions—Ca(II) and non-toxic, renewable and cheap linkers—lactate and acetate. The MOFs are nontoxic and environmentally-benign, and can be used as degradable carriers.

Abstract: Delivery system based on polymeric nanocapsules which contain microemulsions, and their use in the preparation of pharmaceutical, cosmetic and/or alimentary compositions.

Abstract: The present invention provides methods and compositions for treating non-small-cell lung cancer (NSCLC) by administering a) a composition comprising nanoparticles that comprise paclitaxel and an albumin and b) a platinum-based agent (e.g., carboplatin), wherein the individual has diabetes, has four or more metastatic sites, and/or is at least about 70 years old.

Abstract: The present invention provides methods of assessing suitability of a pharmaceutical composition for medical use. The pharmaceutical composition comprises nanoparticles comprising rapamycin coated with albumin and a non-nanoparticle portion comprising albumin and rapamycin.

Abstract: The present invention relates to formulations useful for affecting the behaviour of mosquitoes. More specifically, the present invention relates to formulations for activating mosquitoes such as for attracting mosquitoes. The present invention further provides methods and dispensers incorporating these formulations. The formulation comprises a thio compound as the active, preferably a thioether such as allyl methyl sulphide (AMS), 1-methylthio-propane, 3-methylthio-propanol (MTPL), (E)-1-methylthio-1-propene, (Z)-1-methylthio-1-propene, or derivatives thereof.

Abstract: Method of treating bacterial vaginosis in a subject in need thereof involving administering to the subject a therapeutically effective amount of secnidazole in a microgranule formulation, wherein the microgranule formulation comprises a plurality of microgranules having a volume-weighted particle size distribution within a microgranule population, wherein the volume-weighted particle size distribution as measured from a representative sample of the microgranule population comprises (a) 10% of the microgranule population having a volume-weighted particle size about no less than 470 micrometers; (b) 50% of the microgranule population having a volume-weighted particle size between about no less than 640 micrometers and about no more than 810 micrometers; (c) 90% of the microgranule population having a volume-weighted particle size about no more than 1170 micrometers; or (d) a combination thereof, which can include some or all of (a) through (c) above.

Abstract: A method of treating chronic kidney disease in a mammalian subject by administering a composition that includes L-arginine, glycine, L-glutamine, L-histidine, L-aspartic acid L-glutamic acid, and L-carnosine.

Abstract: The present disclosure provides a composition consisting of ceftriaxone sodium and sulbactam sodium, a pharmaceutical formulation comprising the same and the application thereof. The composition is characterized by having an X-ray powder diffraction pattern with peaks at specific angles. The pharmaceutical formulation according to the present disclosure have better antibacterial activity and stability compared with known compositions, and are thus very suitable for the treatment of bacterial infections, especially for the treatment of refractory urogenital system infections caused by Neisseria gonorrhoeae which has drug-resistance to a variety of antibiotics (?-lactams, tetracyclines, macrolides, fluoroquinolones and aminoglycosides).

Abstract: The present invention relates to a solid makeup and/or care cosmetic composition in the form of a compact powder, comprising, in a physiologically acceptable medium, at least: one pulverulent phase, one organopolysiloxane elastomer, one emulsifying system, one hydrophilic gelling agent, and one organic non-volatile oil present in a content of greater than or equal to 1% by weight relative to the total weight of the composition. The invention also relates to an intermediate composition for the preparation of such a cosmetic composition, to a process for manufacturing this cosmetic composition, and to a process for coating the skin with the said cosmetic composition.

Abstract: Described herein are polymeric nanoparticles that include a therapeutic agent which is 2-(3-((7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide (also known as AZD1152 hqpa) or a pharmaceutically acceptable salt thereof, and methods of making and using such therapeutic nanoparticles.

Abstract: The present invention relates to a low-viscosity cosmetic composition and methods using a natural emulsifying agent. More specifically, the present invention relates to a cosmetic composition using a naturally derived saccharide-based surfactant in place of a chemical surfactant and realizing a low-viscosity formulation to offer safety to the skin, feel good on the skin with fast absorption, give stability to the formulation and add luster to the skin in an effective manner.

Abstract: A dry consumable preparation and related methods are disclosed. The preparation has a bulking agent, and a cannabinoid and/or a cannabinoid extract containing one or more cannabinoids plated onto the bulking agent. The preparation also has an effervescence agent. The effervescence agent has sodium bicarbonate, potassium bicarbonate, and at least one acid, the at least one acid having at least one of citric acid, tartaric acid, or malic acid. The effervescence agent further has a ratio of sodium bicarbonate to potassium bicarbonate to the acid(s) that creates a chemical pH buffering system at a targeted pH range when the dry consumable preparation is added to a targeted amount of water.

Abstract: The present embodiments relate to a nail coating having a major advantage in that it enables a nail coating to adhere to a natural nail or uncoated nail for long wear periods without adhesion loss or other signs of breakdown of the coating. Nail topcoats with improved abrasion resistance are also disclosed. Adhesion of a composition for nail coatings be improved by addition of a polyhedral oligomeric silsesquioxane (POSS). Nail coating compositions that benefit from the addition of a POSS include enamels, reactive composition such as those containing acrylates, solventless compositions and water-based compositions.