Patents Examined by P. Kathryn Wright
  • Patent number: 12638465
    Abstract: A test tube rack dispatching method, a pipeline analysis system and a test tube rack. Said method is applied to a pipeline analysis system. The pipeline system comprises a sample conveying mechanism, at least two test devices and at least two test platforms corresponding to the at least two test devices, the sampling mechanism being connected to the at least two test platforms. Said method comprises: scanning a readable and writable label of a test tube rack placed in the pipeline system, so as to read test mode information corresponding to the test tube rack; and dispatching, by the sample conveying mechanism, the test tube rack to a test platform corresponding to the test mode information, so as to test samples on the test tube rack by a test device corresponding to the test platform.
    Type: Grant
    Filed: June 24, 2021
    Date of Patent: May 26, 2026
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Junwei Zhang, Xuerong Li, Changyin Yan
  • Patent number: 12629687
    Abstract: A container (30) includes a plurality of accommodation portions (310) accommodating the sample, and a lid portion (320) closing the plurality of accommodation portions (310). The treatment apparatus (6) includes a container support portion (41) configured to support the plurality of accommodation portions (310), and a container fixing portion (42) configured to overlap the lid portion (320). The container fixing portion (42) is configured to sandwich the container (30) together with the container support portion (41). The container fixing portion (42) is provided in a manner of being able to be opened and closed with respect to the container support portion (41). A plurality of hole portions (411) are provided in the container support portion (41). A plurality of hook portions (420) inserted into the plurality of hole portions (411) and engaging with edge portions (411a) of the plurality of hole portions (411) are provided in the container fixing portion (42).
    Type: Grant
    Filed: November 4, 2021
    Date of Patent: May 19, 2026
    Assignee: Yokogawa Electric Corporation
    Inventor: Masahiro Kuwata
  • Patent number: 12631661
    Abstract: To provide an automatic analyzer and a sample aspiration method in an automatic analyzer capable of analyzing a sample of further minute amount compared than before. In aspirating the sample, a sample dispensing mechanism 13, 14 is controlled so as to detect the liquid level L1, to thereafter allow a dispensing probe 13a, 14a of the sample dispensing mechanism 13, 14 to be dropped and stopped below the liquid level L1, to thereafter allow the dispensing probe 13a, 14a of the sample dispensing mechanism 13, 14 to be elevated and stopped, and to thereafter allow the dispensing probe 13a, 14a of the sample dispensing mechanism 13, 14 to be further dropped while aspirating the sample.
    Type: Grant
    Filed: January 27, 2022
    Date of Patent: May 19, 2026
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Yoshihiro Kabe, Takuya Takahashi, Masashi Fukaya, Kenshiro Sakata
  • Patent number: 12629671
    Abstract: An automated pipetting system includes a pipettor. The pipettor includes a pipetting channel, a first plunger mechanism operable to change a pressure in the pipetting channel to aspirate or dispense a liquid, and a second plunger mechanism operable to change the pressure in the pipetting channel to aspirate or dispense the liquid.
    Type: Grant
    Filed: May 11, 2022
    Date of Patent: May 19, 2026
    Assignee: REVVITY HEALTH SCIENCES, INC.
    Inventors: Thomas Perroud, Thomas Rawlins, Hans-Juergen Tiedtke, Kai Hassler
  • Patent number: 12625155
    Abstract: Provided is an automatic analyzer capable of reliably closing an openable lid provided in an opening for accessing a region covered by a cover. An automatic analyzer includes an incubator cover disposed to cover a preprocessing region provided on an operation surface on a housing, an openable lid disposed to openably cover an opening portion provided in the incubator cover in order to access the inside from the outside of the preprocessing region, and a safety cover disposed to cover upper portions of the operation surface and the preprocessing region, and the openable lid is moved to a closed position in association with movement of the safety cover from an opened position to the closed position in a case where the openable lid is at the opened position and the safety cover is at the opened position.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: May 12, 2026
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Tsukasa Suenari, Takenori Okusa, Taichiro Yamashita
  • Patent number: 12616974
    Abstract: Described are exemplary embodiments of a syringe identification system for use with a positive displacement pipette, such as a handheld powered positive displacement pipette. An exemplary syringe identification system may include a sensor, such as a color sensor, that is located at or near a distal end of the pipette and arranged such that the sensor is operative to read an identifying marking(s) on a syringe that has been installed to the pipette. The sensor may be a color sensor having an illumination source and configured to read a color code on the syringe. The color code may be usable to identify the syringe to the pipette.
    Type: Grant
    Filed: February 22, 2024
    Date of Patent: May 5, 2026
    Assignee: Mettler-Toledo Rainin, LLC
    Inventors: Richard Hill, Michael McNaul, Bob Wells, Simon Shakespeare, Matthew Newman
  • Patent number: 12618750
    Abstract: A method for generating a series of ultra-thin sections of a microscopic sample is provided. The method includes detaching the sections from the sample using an ultramicrotome. The sections detached from the sample are made to float on a liquid surface and thereafter are transferred onto a solid carrier element. The method also includes determining, for at least one of the sections detached from the sample, a position and an orientation on the solid carrier element by monitoring the placement of the sections onto the solid carrier element using a monitoring system comprising a camera, and obtaining monitoring data.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: May 5, 2026
    Assignee: LEICA MIKROSYSTEME GMBH
    Inventors: Robert Kirmse, Robert Lange, Peer Oliver Kellermann, Robert Ranner, Mario Noessing
  • Patent number: 12618860
    Abstract: An automatic analysis device is provided with: a sample disk for holding a sample container that accommodates a sample; a reagent disk for holding a reagent container that accommodates a reagent; at least two different measuring units that respectively perform different types of analyses; a control part that controls the measuring units; and a display part that displays: a work flow area in which the flow of operation of the two or more measuring units is displayed; and an overview area in which the usable or unusable states of the respective measuring units are displayed, wherein the overview area has a unit necessity-of-use selection part that can select whether using each of the measuring units is necessary, and the control part controls the display part so as to change the display of the work flow area on the basis of the information set in the unit necessity-of-use selection part.
    Type: Grant
    Filed: July 14, 2023
    Date of Patent: May 5, 2026
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Chie Yabutani, Takumi Yamada, Masahiko Iijima
  • Patent number: 12613216
    Abstract: A gas sensor system includes a first pipe through which a specimen atmosphere is conveyed; a second pipe through which humidified air is conveyed, the humidified air being hotter and more humid than the specimen atmosphere, the humidified air having a lower water vapor pressure than a saturation water vapor pressure; a mixing device mixing the specimen atmosphere and the humidified air so that a water vapor pressure of mixed air of the specimen atmosphere and the humidified air is less than a saturation water vapor pressure; a third pipe connected with the mixing device; a cooling device cooling the mixed air conveyed through the third pipe so that the water vapor pressure of the mixed air becomes the saturation water vapor pressure; and a chemical sensor device including a sensor surface to which the mixed air cooled by the cooling device is supplied.
    Type: Grant
    Filed: February 21, 2023
    Date of Patent: April 28, 2026
    Assignee: KABUSHIKI KAISHA TOSHIBA
    Inventors: Hiroshi Hamasaki, Yoshiaki Sugizaki, Hideyuki Tomizawa
  • Patent number: 12605713
    Abstract: A reagent container includes a base defining a plurality of wells having openings exposed at an upper surface of the base and a tube receptacle. The plurality of wells include a first set of wells and a second set of wells. Each well of the first set of wells has an opening to a well bore and a channel in communication with the well bore. The opening has a first portion disposed over the well bore and a second portion disposed over the channel. The first portion has a larger area than the second portion. An angle defined by tangents to the inner surface of the first and second portions at a junction between the first and second portions is at least 100° and not greater than 180°. The reagent container further includes a top coupled over the top surface of the base and defining windows providing access to the openings of the plurality of wells and the tube receptacle.
    Type: Grant
    Filed: December 19, 2023
    Date of Patent: April 21, 2026
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventor: Earl Zergiebel
  • Patent number: 12601662
    Abstract: Various examples of systems and methods are provided for slide processing. In one example, among others, a system for processing microscope slides includes a slide positioner that can adjust a position of a slide and a slide treatment system that can dispense a micro stream of a fluid at a location on the slide when the slide is positioned beneath a jet nozzle of the slide treatment system. The system can include a slide sled that can align a smearing slide with a surface of the slide including a fluid sample is disposed, and support the smearing slide at a predefined angle with respect to the surface of the slide. In another example, a method includes obtaining a slide including a sample disposed on a surface, positioning the slide below to a jet nozzle, and dispensing a micro stream of a fluid onto the sample using the jet nozzle.
    Type: Grant
    Filed: July 23, 2025
    Date of Patent: April 14, 2026
    Assignee: Zomedica Inc.
    Inventor: William Eugene Campbell
  • Patent number: 12601753
    Abstract: An automatic analyzer includes: a plurality of dispensing units; and a plurality of pump units connected to the respective dispensing units. Each of the plurality of pump units includes: a syringe tube that has a liquid port at one end and an opening at another end; a syringe base that is attached to the opening at the other end of the syringe tube; a plunger that penetrates the syringe base and whose tip end is inserted inside the syringe tube; a seal piece that is configured to seal a gap between the plunger and the syringe base; an actuator; and a power transmission mechanism that connects the actuator and the plunger. Each plunger of the plurality of pump units has an individually set diameter and a different thickness. At least one of the syringe base and the syringe tube represents the diameter of the corresponding plunger in appearance.
    Type: Grant
    Filed: February 3, 2021
    Date of Patent: April 14, 2026
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Shunsuke Miyamoto, Hiroyuki Mishima, Hajime Yamazaki, Takeshi Setomaru, Akihiro Yasui
  • Patent number: 12594551
    Abstract: A tissue sample that has been removed from a subject can be properly fixed for evaluation using the disclosed transporter assembly for carrying a tissue sample and method for fixing an unfixed tissue sample. In one embodiment, the disclosed assembly includes a transport container, a fixative in the transport container, and a cooling device that reduces and/or maintains the temperature of the fixative to perform a pre-soaking process at a temperature of less than about 7° C. The pre-soaking process can, for example, be performed during sample transport or during extended periods of storage, such as over a weekend.
    Type: Grant
    Filed: June 28, 2021
    Date of Patent: April 7, 2026
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Nathan Crum, Timothy Keller, Alastair Laing, Michael Otter, Vinnie Petre, Elizabeth Pigman, Taylor Shingler, Stacey Stanislaw, Benjamin Stevens
  • Patent number: 12596128
    Abstract: Provided is an automatic analyzer capable of appropriately controlling most of the temperature of an incubator even when local temperature fluctuation occurs. An automatic analyzer for analyzing a specimen includes an incubator for holding a plurality of vessels that store a mixed liquid of the specimen and a reagent, a heat source for heating or cooling the incubator, a plurality of temperature sensors provided at different positions of the incubator and measuring the temperature, and a control unit for controlling an output of the heat source based on a difference between a target temperature and the highest temperature or the lowest temperature among the measured temperatures of the temperature sensors.
    Type: Grant
    Filed: January 26, 2021
    Date of Patent: April 7, 2026
    Assignee: Hitachi High-Tech Corporation
    Inventors: Hitomi Tsuji, Yuya Matsuoka
  • Patent number: 12584831
    Abstract: Various examples of systems and methods are provided for slide processing. In one example, among others, a system for processing microscope slides includes a slide positioner that can adjust a position of a slide and a slide treatment system that can dispense a micro stream of a fluid at a location on the slide when the slide is positioned beneath a jet nozzle of the slide treatment system. The system can include a slide sled that can align a smearing slide with a surface of the slide including a fluid sample is disposed, and support the smearing slide at a predefined angle with respect to the surface of the slide. In another example, a method includes obtaining a slide including a sample disposed on a surface, positioning the slide below to a jet nozzle, and dispensing a micro stream of a fluid onto the sample using the jet nozzle.
    Type: Grant
    Filed: July 23, 2025
    Date of Patent: March 24, 2026
    Assignee: Zomedica Inc.
    Inventor: William Eugene Campbell
  • Patent number: 12584864
    Abstract: A point-of-care testing (POCT) fully-automatic chemiluminescence device based on a multi-channel parallel pretreatment technology includes a support. The support is provided thereon with a reaction chamber assembly, which reciprocates linearly relative to the support. A multi-channel parallel pretreatment assembly and a photomultiplier tube (PMT) assembly are arranged on the support and are located above the reaction chamber assembly. The multi-channel parallel pretreatment assembly is configured to transfer, clean, and separate reagents in reagent strips in the reaction chamber assembly. The PMT assembly is configured to detect a luminescence value of the cleaned and separated reagents.
    Type: Grant
    Filed: January 17, 2023
    Date of Patent: March 24, 2026
    Assignee: Chengdu Illumaxbio Technology Co., LTD
    Inventors: Xingpeng Zhang, Le Chang, Rundan Wei
  • Patent number: 12584824
    Abstract: The invention is directed to a process for extracting target cells from a three dimensional biological specimen by the steps imaging the three dimensional specimen; identifying target cells; registering the spatial parameters (x,y,z coordinates) of the target cells; and extraction of target cells according to their spatial parameters
    Type: Grant
    Filed: February 25, 2021
    Date of Patent: March 24, 2026
    Inventors: Andreas Bosio, Heinrich Spiecker
  • Patent number: 12578354
    Abstract: A pipette assembly configured to aspirate liquid from a well having a cover includes: a pipette including a terminal end; a pipette tip detachably coupled to the terminal end; and a vibration inducer configured to vibrate the pipette tip when at least a portion of the pipette tip is located in the well thus reducing stiction between the cover and the pipette tip. This minimizes the pipette tip from getting detached from the pipette and stuck in the cover. Other systems and methods including vibrating a pipette tip are disclosed.
    Type: Grant
    Filed: October 6, 2020
    Date of Patent: March 17, 2026
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventor: Simin Yao
  • Patent number: 12546793
    Abstract: An automatic analyzer for making measurements for different analysis processes by a compact mechanism. The apparatus performs inspection for plural different analysis processes and includes: an incubator for holding plural reaction vessels on circumferential positions, first and second dispensing mechanisms each having a dispensing nozzle capable of arc-shaped movement around a rotational axis and vertical movement, in which a first locus of an arc-shaped movement of the dispensing nozzle of the first dispensing mechanism and a second locus of the arc-shaped movement of the dispensing nozzle of the second dispensing mechanism intersect the circumference of the incubator where the reaction vessels are arranged, while the first locus and the second locus do not intersect, the first dispensing mechanism is used in a first inspection having a first reaction period, and the second dispensing mechanism is used in a second inspection having a second reaction period longer than the first reaction period.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: February 10, 2026
    Assignee: Hitachi High-Tech Corporation
    Inventors: Eiichiro Takada, Yoshihiro Yamashita, Hidetsugu Tanoue, Masashi Fukaya, Fumiya Nehashi
  • Patent number: 12539509
    Abstract: The invention relates to a pipette with a body for receiving a displacement device, the displacement device comprising a displacement chamber and a movable boundary element for bounding a pipetting stroke of the pipette. The pipette furthermore has an operating element for setting the pipetting volume of the pipette by movement of the boundary element in the body and for performing a pipetting operation, the operating element being in operative connection with a piston movable in the displacement chamber of the displacement device. The pipette furthermore comprises a counter for displaying the set pipetting volume and a locking mechanism for locking and/or unlocking volume setting by the operating element. It is provided that, on actuation of the operating element, the operating element is configured to perform a pipetting operation, to transfer the locking mechanism into a locked position and to lock adjustment of the pipetting volume.
    Type: Grant
    Filed: February 21, 2023
    Date of Patent: February 3, 2026
    Assignee: Eppendorf SE
    Inventors: Julian Bikmohammadi, Andreas Ratzka, Elena Schmidt, Florian Tesch, Christian Baasch, Christiane Markau, Michael Strutz, Anne Oehlmann, Kevin Höricke, Ulrike Gast, Olaf Sauer