Abstract: Pesticidal compositions for the control of dust mites containing one or more plant essential oils. In addition, the present invention is directed to a method for controlling dust mites by applying a pesticidally-effective amount of the above pesticidal compositions to a locus where pest control is desired.

Abstract: The object of the present invention is to provide a composition comprising a Withania somnifera extract. Another object of the invention is to provide a method for increasing male sperm count in-vivo with a composition comprising Withania somnifera extracts.

Abstract: The present invention relates to promoting whole body health in humans and animals by using topical oral compositions comprising a safe and effective amount of chlorite ion in admixture with a pharmaceutically acceptable carrier, said compositions being effective in controlling bacterial-mediated diseases and conditions present in the oral cavity and inhibiting the spread into the bloodstream of oral pathogenic bacteria and associated bacterial toxins and resultant inflammatory cytokines and mediators. The present invention also encompasses methods of use of these compositions by topically applying to the oral cavity, a safe and effective amount of chlorite ion to promote and/or enhance whole body health in humans and other animals.

Abstract: The invention provides herbal compositions with antiviral properties comprising extracts of Foeniculum vulgare, Nigella sativa, Centaurium erythrae (spicatum or pulchellum), Cynara cardunculus var scolymus, Inula helenium (viscosa), Solenostema argel, Sesbania aegyptiaca (sesban), Cichorium intybus (pumilum), Cymbopogon proximus, Hemidesmus indicus, Rheum officinale, Cuminum cyminum, and combinations thereof. The invention further provides herbal compositions with antiviral properties comprising an extract from the leaves or seed of Sesbania aegyptiaca (sesban) and at least one additional herbal extract selected from the group consisting of seed of Nigella sativa, shoot of Cichorium intybus (pumilum), whole plant of Cymbopogon proximus, rhizome of Hemidesmus indicus, leaves of Solenostema argel, rhizome of Rheum officinale, and fruit of Ecballium elaterium.

Abstract: Process for the preparation of the cyclic pentapeptide cyclo(Arg-Gly-Asp-DPhe-NMeVal) by cyclization of a linear pentapeptide selected from the group consisting of H-Arg(Pbf)-Gly-Asp(OBzl)-DPhe-NMeVal-OH, H-Gly-Asp(OBzl)-DPhe-NMeVal-Arg(Pbf)-OH, H-Asp(OBzl)-DPhe-NMeVal-Arg(Pbf)-Gly-OH, H-DPhe-NMeVal-Arg(Pbf)-Gly-Asp(OBzl)-OH or H-NMeVal-Arg(Pbf)-Gly-Asp (OBzl)-DPhe-OH, subsequent protective group removal and, if appropriate, further conversion into its physiologically acceptable salts.

Abstract: The present invention provides an herbal pharmaceutical composition comprising the root of scutellaria, the rhizome of coptis, the root and rhizome of rhubarb, and the dry powders of the root of ginseng (or American ginseng) or the rhizome of ginger. The herbal pharmaceutical composition is effective in preventing patients from developing or treating patients with cardiovascular diseases, which include, but are not limited to, hypertension, coronary heart disease, cerebrovascular disease, peripheral vascular disease, heart failure, rheumatic heart disease, congenital heart disease, and cardiomyopathies. The present invention also provides methods for preparing and using the herbal pharmaceutical composition.

Abstract: The present invention provides a method for the extraction of a proteinase inhibitor from plant tissue. The extraction of the proteinase inhibitor begins with the addition of an alcohol-free, aqueous solution of an organic acid and a salt to plant tissue. The extraction solution and plant tissue are comminuted to reduce the average particle size of the plant tissue to improve extraction efficiencies. A weight ratio of between about 1:1 and about 1:10 extraction solution to plant tissue is used. In extracting proteinase inhibitor II from potato tubers, the extraction solution utilizes formic acid and sodium chloride, and the average particle size is reduced to between about 100 and 1500 microns. The process has been demonstrated to be cost-effective and provide high yields of the target proteinase inhibitor on commercial scales.

Abstract: A compound is extracted from vegetable material, wherein the vegetable material is reduced and treated with a solvent. According to the invention, the vegetable material is frozen using a liquid nitrogen and in frozen condition reduced in size. According to two important embodiments, the vegetable material comes from the ginkgo tree, in particular fresh leaves, and water is used as a solvent. The invention also relates to a pharmaceutical preparation and a cosmetic preparation comprising as active component a compound obtained by the method according to the invention.

Abstract: The present invention relates to high-throughput systems and methods to prepare a large number of component combinations, at varying concentrations and identities, at the same time, and high-throughput methods to test tissue barrier transfer, such as transdermal transfer, of components in each combination. The methods of the present invention allow determination of the effects of inactive components, such as solvents, excipients, enhancers, adhesives and additives, on tissue barrier transfer of active components, such as pharmaceuticals. The invention thus encompasses the high-throughput testing of pharmaceutical compositions or formulations in order to determine the overall optimal composition or formulation for improved tissue transport, such as transdermal transport.

Abstract: A preparation based on plant extracts, with an antioxidant action which is particularly useful in the treatment of circulation and chronic degenerative problems and in the treatment of hypertension, characterized in that its active ingredients comprise Ginkgo biloba biflavones, catechin and/or epicatechin, cumarin and derivatives thereof and a component selected from among madecassic acid, asiatic acid, asiaticoside or combinations thereof.

Abstract: A non-aqueous method of extracting olive leaves, and products formed containing the olive-leaf extract. The resulting extract is used, preferably together with vitamins C, E and A or components thereof to form a skin treatment product that has efficacy as a photoprotectant and antioxidant.

Abstract: The present invention relates to compositions and methods for enhancement of sexual pleasure and disorders related to sexual pleasure especially in mammalian females. The present invention relates to all aspects of modulating the female sexual response, including female sexual dysfunction such as female sexual arousal disorders (FSAD), orgasmic disorders, sexual pain disorders and enhancing female sexual pleasure and satisfaction. The present invention relates to compositions comprising botanical extracts and active agents which are useful to treat or affect any of the aforementioned conditions. The present invention relates to a composition, preferably for topical or local use, which comprises one or more of the following ingredients; including, but not limited to, borage seed oil, Angelica pubescens root and other Angelica species, Coleus forskohlii extract, vinpocetine, ferulic acid, magnesium, ascorbyl palmitate, capric triglyceride, caprylic triglyceride, silica and equivalents thereof.

Abstract: Methods and compositions are described which allow for the sublingual absorption of peptides by oral administration. A liquid and a tablet format for the sublingual approach are demonstrated. The peptides are stable at room temperature and in the compositions herein described.

Abstract: A composition for reducing or stabilizing blood pressure and relieving headaches comprises (a) a first component comprising (i) tea, or (ii) tea and vitamin B6, or (iii) a combination of vitamin C and vitamin B6, or (iv) a combination of tea, vitamin C, and vitamin B6, and (b) a sulfur-containing amino acid. Preferably, the composition is provided in tablet or capsule form.

Abstract: This invention relates to a nutritional intervention composition in a dry power form for enhancing satiety prior to a meal and extending satiety after a meal in a calorically efficient fashion. The dry nutritional composition includes protein, caseinmacropeptides (CMP) or glycomacropeptides (GMP) or any hydrolysis product of GMP, long chain fatty acids, soluble and/or insoluble fibers. The dry nutritional composition includes protein in the range of 0.21% to 88.30%, glycomacropeptide in the range of 0.05% to 87.72%, oleic acid in the range of 2.27% to 97.25%, soluble fibers in the range of 0.19% to 79.05%, and insoluble fibers in the range of 0.19% to 79.05%. The composition may also include plant saponins, calcium and cholestyramine.

Abstract: A product and process for stabilizing Aloe vera gel is disclosed. The process includes the steps of rapidly heating the Aloe vera gel to a temperature in the range of from about 35° C. to about 80° C., adding to the heated Aloe vera gel one or more stabilizing antioxidants, and rapidly cooling the heated Aloe vera gel to a temperature in the range of from about 20° C. to about 30° C. The stabilizing antioxidants may be a tocotrienol/tocopherol blend, rosmarinic acid, polyphenols, or any combination thereof.

Abstract: Microencapsulated and/or enteric coated compositions containing a mixture of sorbents with specific adsorption affinities for uremic toxins including ammonia, urea, creatinine, phenols, indoles, and middle molecular weight molecules and a bacterial source which metabolizes urea and ammonia are provided. Also provided are methods of using these compositions to alleviate symptoms of uremia in patients.

Abstract: A method for removing protein impurities from extracts of protease inhibitor-containing plant material. Plant materials containing protease inhibitors, such a potato tubers that contain protease inhibitor II, are extracted using an alcohol-free solvent. The proteins present in the extract include impurities other than the protease inhibitor, specifically Kunitz, Bowman-Birk and carboxypeptidase inhibitors. The extract is subjected to heat treatment to denature and precipitate the unstable protein impurities followed by centrifugation to remove the precipitate. Ultrafiltration in the presence of a buffer removes the Bowman-Birk and carboxypeptidase inhibitors. The resulting purified protease inhibitor has applicability in the control of obesity and diabetes.

Abstract: The disclosure provides a method for administering an agent to an avian species by in ovo delivery of an implant releasably containing the agent. In one embodiment, the method is particularly advantageous for stimulating an immune response in a bird by in ovo administration of a biocompatible implant releasably containing an immunogen. The implant can provide for sustained or delayed release of the immunogen or both. The amount of immunogen that is released from the implant into the bird is preferably sufficient to effectively stimulate a primary immune response to the immunogen. Other agents which can be administered according to the method of the invention are disclosed.

Abstract: A novel strain of Streptomyces galbus that produces metabolites and exhibits pesticidal activity is disclosed. In addition, a supernatant of the novel strain with pesticidal activity is disclosed. An ethyl acetate-soluble, small molecular weight, alkali stable, metabolite produced by the novel strain Streptomyces galbus with pesticidal activity against lepidopteran insects is provided. Also included are methods for fermenting the novel strain of Streptomyces galbus and increasing the bioactivity of the pesticidal activity. Also included are methods for protecting or treating plants from caterpillars comprising the step of applying to a plant an effective amount of the novel Streptomyces galbus strain, the metabolites produced by the strain, or a combination thereof.