Patents Examined by Patricia Park
  • Patent number: 10183176
    Abstract: A therapeutic apparatus comprising: a magnetic resonance imaging system adapted for acquiring a set of magnetic resonance imaging data in an imaging zone, the magnetic resonance imaging system comprising a means for generating a magnetic field, —a guiding means adapted for guiding a beam of charged particles to a target zone within a subject, wherein the imaging zone comprises the target zone, a zone determination means adapted for determining the location of the target zone within the subject using the set of magnetic resonance imaging data, a trajectory calculation means adapted for calculating a trajectory of the beam using magnetic field data being descriptive of the magnetic field such that the calculated trajectory reaches the target zone, a control means adapted for controlling the guiding means using the calculated trajectory such that the beam follows the calculated trajectory.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: January 22, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Michael Harald Kuhn, Johannes Adrianus Overweg
  • Patent number: 10172674
    Abstract: An intracorporeal marker system includes a tissue marker pellet comprised of a polysaccharide material. The intracorporeal marker system may also include a fibrous marker of bioabsorbable fibers. In one embodiment, for example, an outer layer of bioabsorbable fibers is disposed around at least part of an inner core of bioabsorbable fibers.
    Type: Grant
    Filed: June 20, 2013
    Date of Patent: January 8, 2019
    Assignee: SenoRx, Inc.
    Inventors: Michael L. Jones, Paul Lubock, John Merritt
  • Patent number: 10173077
    Abstract: A therapeutic apparatus comprising: a magnetic resonance imaging system adapted for acquiring a set of magnetic resonance imaging data in an imaging zone, wherein the magnetic resonance imaging system comprises a means for generating a magnetic field, a guiding means adapted for guiding a beam of charged particles to a target zone within a subject such that the beam encloses an angle with the magnetic field lines of the magnetic field within the imaging zone, the angle being between 0 degrees and 30 degrees, wherein the imaging zone comprises the target zone, a zone determination means for determining the location of the target zone within the subject using the set of magnetic resonance imaging data.
    Type: Grant
    Filed: November 19, 2009
    Date of Patent: January 8, 2019
    Assignee: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventor: Johannes Adrianus Overweg
  • Patent number: 10154797
    Abstract: MRI based molecular imaging is strongly supported by the accurate quantification of contrast agents. According to an exemplary embodiment of the present invention, contrast agent is applied on the basis of a multiple injection application scheme, during which changes in relaxation rate are determined. This may provide for an accurate determination of rumor vascularity via MRI relaxometry.
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: December 18, 2018
    Assignee: Koninklijke Philips N.V.
    Inventors: Hannes Dahnke, Tobias Schaeffter
  • Patent number: 10157491
    Abstract: An apparatus for visualizing image material in a multimodal imaging environment. Images (XF, USV) from an X-ray imager (100) and an ultrasound probe (USP) are fused into an interactive graphics display (GUI) to form a 3D scene, where, alongside to a 3D rendering (USS) of an ultrasound volume (USV) an X-Ray projection plan (XF) is displayed in perspective within the same scene. The rendering is according to a user selected view (UV) which is changeable upon user interaction with the interactive graphics display (GUI).
    Type: Grant
    Filed: December 24, 2013
    Date of Patent: December 18, 2018
    Assignee: Koninklijke Philips N.V.
    Inventors: Raoul Florent, Olivier Pierre Nempont, Pascal Yves Francois Cathier, Niels Nijhof
  • Patent number: 10154785
    Abstract: A system and method for fluorescence imaging of tissue in vivo and in situ, e.g., for minimally invasive diagnosis of patients. A fluorescent imaging system is provided that has a dye carrier coupled to the distal end of a probe containing a fiber optics bundle, which allows for the introduction of at least one fluorescent dye therein the dye carrier into a portion of the tissue of interest of a subject or patient when the dye carrier is selectively brought into contact with the portion of the tissue of interest. The resulting fluorescence images permit the acquisition of diagnostic information on the progression of diseases at cellular/tissue level in patients.
    Type: Grant
    Filed: January 18, 2013
    Date of Patent: December 18, 2018
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Frank B. Sachse, Robert Hitchcock, Chao Huang, Aditya K. Kaza
  • Patent number: 10143443
    Abstract: A method and system for analyzing stiffness in a volume of tissue, the method including: emitting acoustic waveforms toward the volume of tissue with an array of ultrasound transmitters; detecting, with an array of ultrasound receivers, a set of acoustic signals derived from acoustic waveforms transmitted through the volume of tissue; generating, from the set of acoustic signals, a sound speed map and an acoustic attenuation map of a region of the volume of tissue, generating a stiffness map derived from combination of a set of sound speed parameter values of the sound speed map and a corresponding set of acoustic attenuation parameter values of the acoustic attenuation map, the stiffness map representing the distribution of the stiffness parameter across the region; and at a display in communication with the computer processor, rendering a stiffness image of the volume of tissue, based upon the stiffness map.
    Type: Grant
    Filed: May 4, 2015
    Date of Patent: December 4, 2018
    Assignee: Delphinus Medical Technologies, Inc.
    Inventors: Nebojsa Duric, Peter Littrup, Cuiping Li, Olivier Roy, Steven Schmidt
  • Patent number: 10085679
    Abstract: A system and method for detecting vascular contamination by surgical anesthetic using non-invasive IR spectrophotometry. One embodiment is a method for operating an instrument such as an enhanced pulse oximeter to monitor a patient receiving local anesthetic marked with dye that absorbs infrared light. Light is applied to and detected from tissue of the patient. A signal representative of the detected light is processed to derive patient oxygenation information. The detected light is also processed to derive information representative of the presence of the dye-marked anesthetic. The oxygenation information and the information representative of the presence of anesthetic are displayed. The oxygenation monitoring and display and the anesthetic monitoring and display can occur separately or concurrently. Fluorescing dyes and fluorescence detection approaches are used for anesthetic detection in some embodiments.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: October 2, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Steven R. Clendenen, Clifton R. Haider, Barry K. Gilbert, Oliver William Spees
  • Patent number: 10085718
    Abstract: An ultrasonic probe is composed of a beam having a fixed end and a free end, with an ultrasonic transceiver mounted on the free end. A driving mechanism is used to move said ultrasonic transceiver to one or more predetermined positions by applying an electromagnetic force on the beam.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: October 2, 2018
    Assignee: NOBLE SENSORS, LLC
    Inventors: Gaurav Pandey, Richard S. Koplin, Martin J. Weinberg
  • Patent number: 10076261
    Abstract: A range of technique for investigating a sample such as obtaining images and/or spectral information are described. The techniques include a method for deriving structural information about a sample as a continuous function of the depth below the surface of the sample, a method for evaluating a part of the structure of a sample located between two interfaces within the sample, and a contrast enhancing method and apparatus which has a quick image acquisition time.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: September 18, 2018
    Assignee: TeraView Limited
    Inventors: Donald Dominic Arnone, Bryan Edward Cole, Craig Michael Ciesla
  • Patent number: 10064600
    Abstract: Color values of a Doppler image or Doppler data is considered together with a guideline displayed in the Doppler image, and thus a moving direction of a target body may be easily determined. Furthermore, by displaying a marker indicating a moving direction of the target body in the Doppler image, movement of the target body may be easily and efficiently recognized by using the guideline and the marker.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: September 4, 2018
    Assignee: SAMSUNG MEDISON CO., LTD.
    Inventors: Dong-gyu Hyun, Seok-won Choi
  • Patent number: 10022147
    Abstract: The present invention presents an applicator having a non-reusable static pointing device reversibly attachable to a face of an ultrasound transducer to attach the non-reusable static pointing device to the face of the ultrasound transducer in a consistent and accurate way. The static pointing device attached to the face of the ultrasound transducer is coupled with an ultrasound positioning apparatus and is to produce a linear shadow line in a visualized ultrasonographic field.
    Type: Grant
    Filed: November 8, 2015
    Date of Patent: July 17, 2018
    Inventor: Choon Kee Lee
  • Patent number: 9987505
    Abstract: A method for noninvasively changing the permeability of a region of a subject that includes a desired tissue is provided. More specifically, low-power focused ultrasound (FUS) is employed to alter the permeability of the glomerulus so as to alter the glomerular ultrafiltration coefficient. By employing FUS after administering a microbubble contrast agent to a subject, glomerular filtration is temporarily increased and the clearance of larger molecules, which are normally not filtered by the kidney, is allowed. This method offers new treatment opportunities for renal disease management.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: June 5, 2018
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Ferenc Jolesz, Krisztina Fischer, Nathan McDannold
  • Patent number: 9955940
    Abstract: An echogenic nerve block catheter and an echogenic catheter tip member include an echogenic tip member having a plurality of ridges on a first portion of the tip member and a retainer member is on a second portion of the tip member, and the second portion of the tip member is received within the lumen of the nerve block catheter.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: May 1, 2018
    Assignee: Avent, Inc.
    Inventors: Alfred C. Coats, Louis Lupin, Paul E. Bigeleisen
  • Patent number: 9943286
    Abstract: A computerized method of adapting a presentation of ultrasonographic images during an ultrasonographic fetal evaluation. The method comprises performing an analysis of a plurality of ultrasonographic images captured by an ultrasonographic probe during an evaluation of a fetus, automatically identifying at least one location of at least one anatomical landmark of at least one reference organ or tissue or body fluid of the fetus in the plurality of ultrasonographic images based on an outcome of the analysis, automatically localizing a region of interest (ROI) in at least some of the plurality of ultrasonographic images by using at least one predefined locational anatomical property of the at least one anatomical landmark, and concealing the ROI in a presentation of the at least some ultrasonographic images during the evaluation. At least one anatomical landmark is imaged in the presentation and not concealed by the ROI.
    Type: Grant
    Filed: June 4, 2013
    Date of Patent: April 17, 2018
    Assignee: Tel HaShomer Medical Research Infrastructure and Services Ltd.
    Inventors: David Shashar, Reuven Achiron, Arnaldo Mayer
  • Patent number: 9943277
    Abstract: Embodiments relate to detecting coronary stenosis through spatio-temporal tracking. Aspects include extracting a coronary artery tree from each of a sequence of angiogram images, creating a mean artery tree from the extracted coronary artery trees, and projecting the mean artery tree back onto each of the sequence of angiogram images to recover a complete coronary artery tree for each of the sequence of angiogram images. Aspects also include extracting one or more tubular sections from each of the sequence of angiogram images, estimating an arterial width for each of the one or more tubular sections from each of the sequence of angiogram images, and creating a spatio-temporal surface from the arterial widths of the one or more tubular sections over a time spanned by the sequence of angiogram images. Aspects further include detecting a minimum in the spatio-temporal surface and determining if the minimum is indicative of stenosis.
    Type: Grant
    Filed: April 2, 2014
    Date of Patent: April 17, 2018
    Assignee: International Business Machines Corporation
    Inventors: Colin B. Compas, Tanveer F. Syeda-Mahmood
  • Patent number: 9895135
    Abstract: An ultrasound system has an ultrasound transducer equipped with a position marker and a needle equipped with a position marker. The position markers allow the position and orientation of the transducer and needle to be determined. A display depicts an ultrasound image acquired via the transducer and a graphical element representative of a projection of the longitudinal axis of the needle onto a plane of the ultrasound image. The quality of the position and orientation information from the position markers is monitored, and when quality is below a quality threshold the display indicates this fact.
    Type: Grant
    Filed: May 6, 2010
    Date of Patent: February 20, 2018
    Assignee: Analogic Canada Corporation
    Inventors: Laurent Pelissier, Kris Dickie, Corina Leung, Bo Zhuang
  • Patent number: 9883810
    Abstract: Described herein is an optical coherence tomograph (OCT) angiography technique based on the decorrelation of OCT signal amplitude to provide flow information. The full OCT spectrum can be split into several narrower spectral bands, resulting in the OCT resolution cell in each band being isotropic and less susceptible to axial motion nose. Inter-B-scan decorrelation can be determined using the individual spectral bands separately and then averaged. Recombining the decorrelation images from the spectral bands yields angiograms that use the full information in the entire OCT spectral range. Such images provide significant improvement of signal-to-noise ratio (SNR) for both flow detection and connectivity of microvascular networks compared to other techniques. Further, creation of isotropic resolution cells can be useful for quantifying flow having equal sensitivity to axial and transverse flow.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: February 6, 2018
    Assignee: Oregon Health & Science University
    Inventors: Yali Jia, David Huang, Jason Tokayer, Ou Tan
  • Patent number: 9872656
    Abstract: An imaging capsule with a fail-safe radiation mechanism includes a first rotatable disk with a radiation source mounted thereon and having a collimator structure allowing emission of radiation from radiation source from a few locations on the first disk. A second rotatable disk surrounds the first disk, is rotatable relative to first disk, and includes areas that block radiation and areas that are transparent to emission of radiation. In a rest position, second disk is situated relative to first disk such that areas that block radiation are blocking the emission of radiation from the locations on the circumference of the disk that allow the emission of radiation. A motor is activated to rotate one of the disks and allow emission of radiation. A connector is configured to automatically return first disk and second disk to the rest position when the motor is deactivated.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: January 23, 2018
    Assignee: CHECK-CAP LTD.
    Inventors: Yoav Kimchy, Rafi Sommer
  • Patent number: 9861342
    Abstract: An adjunctive ultrasound mammography system and associated methods use an adjunctive ultrasound display configured for quick, intuitive, interactive viewing of volumetric ultrasound scans, displayed near a conventional x-ray mammogram display. Preferred navigations among a thick-slice image array, a selected enlarged thick-slice image, and planar ultrasound views are described, including a mode in which the planar ultrasound views are updated in real time as a cursor is moved across an active thick-slice image. In one example the thick-slice images are inverted prior to display, with non-breast areas of the image preferably segmented out and reset to dark. The inverted thick-slice images are of more familiar significance to radiologists as they are more like conventional x-ray mammograms and allow benign features to be more easily dismissed as compared to non-inverted thick-slice images.
    Type: Grant
    Filed: April 15, 2013
    Date of Patent: January 9, 2018
    Assignee: U-Systems, Inc.
    Inventors: Shih-Ping Wang, Donald Chin, Fangyi Rao, Nico Karssemeijer