Abstract: A method is provided for producing a microfluidic system on a polymer surface, wherein at least one portion of the polymer surface is irradiated by laser light in a targeted fashion for the spatially-resolved modification of the wettability of the portion of the polymer surface by a liquid sample.

Abstract: Chemical sensors such as carbon dioxide sensors and methods for making such sensors are disclosed. An example carbon dioxide sensor may include a substrate, with a sensing beam supported by the substrate. The sensing beam may be configured to resonant. A sensing layer may be disposed on the sensing beam, wherein the sensing layer may include an amino group and is configured to sense carbon dioxide. In some instances, a reference beam may also be supported by the substrate, and may be configured to resonant. A reference layer may be disposed on the reference beam, wherein the reference layer may includes an amino group that has been poisoned so that it will be substantially non-sensitive to carbon dioxide.

Abstract: Disclosed is a module for rapidly detecting analytes in fluids with high effectiveness and a chip having the module. The module includes a microchannel, which has a filtering zone for removing noise materials and a reaction zone wherein labeling reaction and immobilization reaction for detection of analytes are performed, sample fluid moving through the microchannel due to capillary floating. In a case where the chip having the module is used in detecting analytes in fluids, it is possible to minimize dead volume of sample fluid so that high effective volume ratio can be implemented. Therefore, the chip can be used in detecting analytes from the minimum amount of sample fluid.

Abstract: An absorbing zone for establishing and/or maintaining fluid transport through or along at least one fluid passage is manufactured on the basis of a non-porous substrate having a surface, the non-porous substrate having projections substantially perpendicular to the surface, and the projections having a height, diameter and a distance or distances between the projections such, that lateral capillary flow of the fluid in the zone is achieved.

Abstract: A substrate with hermetically sealed vias extending from one side of the substrate to another and a method for fabricating same. The vias may be filled with a conductive material such as, for example, a fritless ink. The conductive path formed by the conductive material aids in sealing one side of the substrate from another. One side of the substrate may include a sensing element and another side of the substrate may include sensing electronics.

Abstract: A gas-sensing element configured to measure a concentration of a specific component of a gas is mounted to a first circuit board which includes a driving circuit configured to drive the gas-sensing element. A moisture-proof material is disposed over at least one side of the first circuit board disposed in a tubular gas-sensing element case fixed to a sensor case. A gas-sensing chamber is defined by the first circuit board and an inner tubular surface of the gas-sensing element case, and opens at an open end of the gas-sensing element case to receive the gas to be monitored. A second circuit board which includes a control circuit configured to control the gas-sensing element via the driving circuit is fixed to a sensor case, and disposed in a position separate from the gas-sensing chamber such that the second circuit board is kept out of contact with the gas to be monitored.

Abstract: Systems, methods and multi-well plates comprising an array of wells for thermal treatment of chemical or biological samples are disclosed. Each of the wells comprises a bottom opening, an upper opening, inner side walls extending from the bottom opening to the upper opening, a protrusion extending from the inner side walls into the well with a first cross-sectional area and located at a height from the bottom opening which is smaller than the height from the upper opening. A sample chamber with a second cross-sectional area is formed between the bottom opening and the protrusion. An upper chamber with a third cross-sectional area is formed between the protrusion and the upper opening, and in which the first cross-sectional area is smaller than the third cross-sectional area and smaller than or equal to the second cross-sectional area.

Abstract: A foldable specimen rack includes a foldable box that moves from a closed, storage position to an open in-use position. The foldable box may include and open box and open bottom when the box is in the open position. The foldable specimen rack may also include a removable insert member situated adjacent the open top of the foldable box. The removable insert member includes multiple specimen holder receiving slots. Different removable insert members may includes slots that accommodate different size specimen holders.

Abstract: The present invention relates to a test strip for determining and/or quantifying a property of a sample, such as the concentration of an analyte, the pH, the viscosity, or the specific gravity of a fluid specimen. More particularly, the present invention relates to an improved test strip and scale for determining and/or quantifying a property of a sample, such as the concentration of an analyte, the pH, the viscosity, or the specific gravity of a fluid specimen.

Abstract: The present invention generally relates to coating materials, including photoactive coating materials. In some aspects of the invention, a sol-gel is provided that can be formed as a coating on a microfluidic channel. One or more portions of the sol-gel can be reacted to alter its hydrophobicity, in some cases. For instance, in one set of embodiments, a portion of the sol-gel may be exposed to light, such as ultraviolet light, which can be used to induce a chemical reaction in the sol-gel that alters its hydrophobicity. In one set of embodiments, the sol-gel can include a photoinitiator, that upon exposure to light, produces radicals. Optionally, the photoinitiator may be conjugated to a silane or other material within the sol-gel. The radicals so produced may be used to cause a polymerization reaction to occur on the surface of the sol-gel, thus altering the hydrophobicity of the surface. In some cases, various portions may be reacted or left unreacted, e.g.

Abstract: A controlled release and self-resealing vessel assembly for high pressure, microwave assisted chemistry is disclosed. The vessel assembly includes a cylindrical reaction vessel formed of a material that is substantially transparent to microwave radiation. The vessel has angular walls, one closed end for retaining reactants in the lower portions of the vessel, and one open end that defines a mouth for the vessel. The mouth of the cylinder vessel has a lip that is beveled inwardly from the open end. A microwave-transparent solid floating plug closes the mouth of the reaction vessel; with the plug have a frustum portion for engaging the beveled lip when the plug is placed in the mouth of the vessel. A lid exerts a defined axial force against the plug for sealing the plug in the open end of the cylinder with the frustum engaging the lip.

Abstract: The present invention relates generally to encoding samples. More specifically, it relates to barcodes and compositions involving upconverters and methods including them. In a composition aspect of the invention, a composition comprising two or more lanthanide materials is provided. Each lanthanide material comprises a host, an absorber, and an emitter, and the materials emit detectable electromagnetic radiation upon excitation with absorbable electromagnetic energy. One or more relative ratios of emission intensities uniquely identify the composition.

Abstract: Systems and methods to pattern surfaces to create regions of variable adhesive force on a superhydrophobic paper surface. By taking advantage of high surface energy sticky islands on a non-sticky superhydrophobic surface, microliter water drops can be registered or confined at specific locations; selected drops can then be transferred to another patterned substrate and the drops mixed and/or allowed to react without the need for pipettes or other fluid transfer tool.

Abstract: A method for operating a firing plant with at least one combustion chamber and at least one burner, especially a gas turbine, includes an operating characteristic for operating the combustion chamber close to the lean extinction limit defined as a burner group staging ratio (BGVRich). Pressure pulsations (PulsActual) measured in the combustion chamber are processed by a filter device (2) and converted into corresponding signals (PulsActual,Filter(t)). An exceeding/falling short of at least one pulsation limiting value (PulsLimit) is monitored by a monitoring device (3) and adapts a pulsation reference value (PulsRef) in dependence upon the monitoring. The processed pressure pulsations (PulsActual,Filter(t)) are then compared with the adapted pulsation reference value (PulsRef,adapt), and, from this, a correction value ?BGV is determined, by which the burner group staging ratio (BGVRich) is corrected, and as a result operation of the firing plant close to the lean extinction limit is realized.

Abstract: An electrochemical machining process for forming a non-circular hole from a substantially circular hole within a workpiece using an electrode. The electrode is made of an electrically conductive material and has insulated areas in which the electrically conductive material is coated with an insulating material, and exposed areas of metal or conductive material. The insulated areas and exposed areas extending in rows substantially along a longitudinal axis of the electrode. The electrode is first positioned in a substantially circular hole. An electric current is then applied to the electrode to electrochemically remove a predetermined amount of material from the substantially circular hole to form a non-circular hole. A variety of different non-circular shapes are achievable using the process.

Abstract: A microfluidic device including a microvalve includes a first substrate, a second substrate facing the first substrate, an elastic film between the first and second substrates, a microfluidic channel on the second substrate, a valve seat of the second substrate protruding in the microfluidic channel, and a fine structure on a surface of the elastic film, facing the valve seat and which contacts the valve seat when the microvalve is operated.

Abstract: Microfluidic structures and methods for manipulating fluids and reactions are provided. Such structures and methods may involve positioning fluid samples, e.g., in the form of droplets, in a carrier fluid (e.g., an oil, which may be immiscible with the fluid sample) in predetermined regions in a microfluidic network. In some embodiments, positioning of the droplets can take place in the order in which they are introduced into the microfluidic network (e.g., sequentially) without significant physical contact between the droplets. Because of the little or no contact between the droplets, there may be little or no coalescence between the droplets. Accordingly, in some such embodiments, surfactants are not required in either the fluid sample or the carrier fluid to prevent coalescence of the droplets. Structures and methods described herein also enable droplets to be removed sequentially from the predetermined regions.

Abstract: A slide holder comprising a rectangular frame having two side walls facing each other, a first end wall facing a second end wall, the second end wall having a latch pivotally attached thereto, the latch capable of being pivoted in such a manner as to enable locking and unlocking of the slide holder in a slide holder carrier. The slide holder carrier has a first end wall, a first side wall, a second end wall, a second side wall, and a shaft running from the first end wall of the slide holder carrier to the second end wall of the slide holder carrier. At least one slide holder is rotatably mounted on the shaft.

Abstract: This invention relates to a device (1) for detecting energy generated by non-radiative decay generated in a substance (2) on irradiation with electromagnetic radiation. The device (1) comprises a radiation source (6) adapted to generate a series of pulses of electromagnetic radiation, a transducer (3) having a pyroelectric or piezoelectric element and electrodes (4, 5) which is capable of transducing the energy generated by the substance (2) into an electrical signal, and a detector (7) which is capable of detecting the electrical signal generated by the transducer (3). The detector (7) is adapted to determine the time delay between each pulse of electromagnetic radiation from the radiation source (6) and the generation of the electric signal. The device (1) has a wide applicability in the fields of assays and monitoring.

Abstract: A simple and low cost device to detect the presence of mercury or other trace metals in the environment and quantify said concentration by spectrophotometric, colorimetric, or electrical conductivity is disclosed. Owing to its small size, it is suitable for portable mercury detectors or detectors that may be worn as badges in the breathing zone of workers.