Patents Examined by Paul Hyun
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Patent number: 8409872Abstract: A cartridge for use in measuring a component to be measured contained in a sample includes a diluting well for diluting a predetermined amount of the sample to a desired dilution, and a reaction well in which the component to be measured contained in the sample and a substance specifically reacting therewith are allowed to react. A diluting solution is filled in the diluting well in a predetermined amount to provide the desired dilution based on a type of the component to be measured when the predetermined amount of the sample is dispensed in the diluting well by a uniform operation.Type: GrantFiled: October 28, 2002Date of Patent: April 2, 2013Assignee: Mitsubishi Chemical Medience CorporationInventors: Hiroyuki Yokoi, Takashi Kurihara
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Patent number: 8404185Abstract: A system for pre-concentrating analytes in a sample prior to introduction into a chromatographic column is generally disclosed comprising a housing, an adsorbent disposed in the housing, and first and second conduits having an inlet and an outlet, respectively, for transferring fluid out of and into the housing during adsorption/dry purge and desorption stages, respectively. In some embodiments, the inlet of the first conduit and the outlet of the second conduit are both disposed in one end of the housing and are offset from each other with respect to the adsorbent.Type: GrantFiled: April 20, 2006Date of Patent: March 26, 2013Assignee: PerkinElmer Health Sciences, Inc.Inventors: Andrew Tipler, Richard G Edwards, James E. Botelho
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Patent number: 8394341Abstract: A frame for a microfluidic chip may be used together with a laboratory apparatus. The frame is adapted at least for one of the following features: receiving the microfluidic chip; protecting the microfluidic chip; and, positioning the microfluidic chip relative to the frame. The microfluidic chip is movable relative to the frame.Type: GrantFiled: March 2, 2005Date of Patent: March 12, 2013Assignee: Agilent Technologies, Inc.Inventors: Thomas Reinhardt, Martin Baeuerle
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Patent number: 8383042Abstract: Disclosed herein is a holder for biological sample containers such as well plates. The holder comprises a flat vacuum bed surrounded by a seal. A container is placed within the seal and a vacuum is applied, pressing and flattening the lower surface of the sample container against the flat vacuum bed. Samples in all portions of the container may then be imaged without the need to refocus on each portion of the container. For imaging, a sample in a well can be illuminated by a beam of light arranged so that a part or all of the sample is illuminated by direct rays that have not passed through the well plate. The beam is redirected to other parts of the well if a single illumination does not cover the whole well, so that the sample to be imaged using a series of partial images.Type: GrantFiled: March 30, 2010Date of Patent: February 26, 2013Assignee: Molecular Devices (New Milton) Ltd.Inventor: Yonggang Jiang
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Patent number: 8377393Abstract: There is provided a microchip having an introduction portion introducing a liquid, a valve, and an ejection portion ejecting the liquid. The valve connects the introduction portion and the ejection portion, and retains the liquid such that surface tension of the liquid prevents the liquid from being ejected to the ejection portion. The liquid can be ejected from the introduction portion to the ejection portion by applying to the liquid centrifugal force larger than the surface tension of the liquid. Such a microchip according to the present invention has a simple configuration and allows easy control of retaining and flowing of a liquid.Type: GrantFiled: April 12, 2007Date of Patent: February 19, 2013Assignee: Rohm Co., Ltd.Inventor: Shun Momose
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Patent number: 8372359Abstract: A vial retainer system for an automated processing apparatus. The vial retainer system includes a track mounted to the processing apparatus, a rack adapted to slide in a longitudinal direction on the track, and a vial retainer positioned over the rack. The rack is movable in a distal direction to install the rack on the processing apparatus, and in a proximal direction, opposite the distal direction, to remove the rack from the processing apparatus. The rack is adapted to hold one or more vials in an upright orientation. The vial retainer has one or more a sloped surfaces inclined such that a distal end of each sloped surface is closer to the track than a proximal end of each sloped surface.Type: GrantFiled: November 19, 2009Date of Patent: February 12, 2013Assignees: Qiagen Gaithersburg, Inc.Inventors: Bert Jungheim, Andrew Leonard
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Patent number: 8366903Abstract: In a method of manufacturing a printed wiring board, a via reaches from a surface copper layer to an inner-layer copper layer of a multilayer board, and copper layers and insulating layers are alternately layered. The wiring board is machined by a laser, and a process of machining the via includes forming a laser absorbing layer on a surface of a copper layer disposed on the surface of the multilayer board. The laser is irradiated, and an electrolytic etching and removal of the laser absorbing layer is carried out in this order.Type: GrantFiled: August 21, 2008Date of Patent: February 5, 2013Assignee: Hitachi Via MechanicsInventors: Toshinori Kawamura, Haruo Akahoshi, Kunio Arai
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Patent number: 8367024Abstract: According to an example of the invention, a test tube holder includes a holder body including a cylindrical wall defining a cylindrical hollow portion, at least three guide grooves in the cylindrical wall and open on the inner peripheral side and upper end surface side, cam grooves which face the guide grooves and inclined obliquely upward, a plurality of holder members for test tube attachment which are fitted individually in the guide grooves of the holder body so as to be movable vertically and radially, cam pins which engage with the cam grooves so as to guide the holder member vertically and radially, and an urging spring which elastically urges the holder member to be pushed up so that the holder member is pressed upward and toward the inner periphery of the cylindrical wall.Type: GrantFiled: February 1, 2010Date of Patent: February 5, 2013Assignee: AOI Seiki Co., Ltd.Inventor: Teruaki Itoh
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Patent number: 8357340Abstract: A materials analysis device (2) comprises an inner receptacle (4), incorporating a filter (5) at its lower end, within an outer receptacle (6). Gas inlet/outlet ports (8, 10) are arranged to provide a means whereby solvent can be caused to pass between the receptacles (4, 6) via filter (5). Solvent in the receptacles (4, 6) is arranged to be heated and its temperature assessed. In use in one embodiment, a solute material to be analyzed is introduced into outer receptacle (6) and a solvent is introduced into inner receptacle (4). The solvent is caused to pass back and (15) forth between the receptacles (4, 6) via the filter (5) until a saturated solution of the solute is present in inner receptacle (4). This may be removed for analysis. By undertaking the process described at a range of temperatures, a solubility profile for the solute can be determined.Type: GrantFiled: August 16, 2004Date of Patent: January 22, 2013Assignee: Wicken Technology LimitedInventor: Ryszard Jurek Kobylecki
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Patent number: 8349616Abstract: A method for assaying a sample for each of multiple analysis is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones are disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone includes a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte.Type: GrantFiled: November 22, 2007Date of Patent: January 8, 2013Assignee: Clondiag GmbHInventors: Torsten Schulz, Thomas Kaiser, Thomas Uhlig, Klaus Peter Möbius, Alexander Von Schenk Zu Schweinsberg
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Patent number: 8349275Abstract: A microfluidic device with microstructure includes a channel for accommodating an electrolytic solution therein and at least one microstructure formed in the channel. When an alternating-current signal is input to the microfluidic device so that a surface of the microstructure is polarized by a generated electric field, ions having polarity reverse to that of an electrolytic solution will migrate to the surface of the microstructure to form a field-induced electrical double layer to result in electro-osmotic flows at the corners at two sides of the microstructure, which causes formation of relatively fierce circular vortices in the solution. A sensing system and a sensing method using the microfluidic device with microstructure are also disclosed.Type: GrantFiled: January 23, 2009Date of Patent: January 8, 2013Assignee: National Chung Cheng UniversityInventors: Shau-Chun Wang, Lai-Kwan Chau, Wen-Hsin Hsieh, Chia-Yu Lee
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Patent number: 8298487Abstract: An electrochemical sensor with a capillary channel is formed by placing a sacrificial insert and electrodes on a sensor base and applying plastic material. After the plastic material is cured, the sacrificial is removed leaving a capillary channel in the sensor. The inserts may be removed by a tool including a clamp for clamping and holding each insert stationary and a sliding block to which the sensor is secured.Type: GrantFiled: January 18, 2007Date of Patent: October 30, 2012Assignee: Bayer HealthCare LLCInventors: Allen J. Brenneman, Frank W. Wogoman
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Patent number: 8293178Abstract: A chemochromic sensor for detecting a combustible gas, such as hydrogen, includes a chemochromic pigment mechanically mixed with a polymer and formed into a rigid or pliable material. In a preferred embodiment, the chemochromic detector includes aerogel material. The detector is robust and easily modifiable for a variety of applications and environmental conditions, such as atmospheres of inert gas, hydrogen gas, or mixtures of gases, or in environments that have variable temperature, including high temperatures such as above 100° C. and low temperatures such as below ?196° C.Type: GrantFiled: November 6, 2007Date of Patent: October 23, 2012Assignee: The United States of America as Represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Luke B. Roberson, Janine E. Captain, Martha K. Williams, Trent M. Smith, LaNetra Clayton Tate
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Patent number: 8268258Abstract: A package for an object having a hydrophilic surface includes at least one of a loose cover for the hydrophilic surface and an adsorbing surface, the affinity of which for apolar gases is equal to or greater than that of the hydrophilic surface.Type: GrantFiled: January 30, 2009Date of Patent: September 18, 2012Assignee: Roche Diagnostics Operations, Inc.Inventors: Brigitte Niederberger, Irio Giuseppe, Michael Glauser
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Patent number: 8262989Abstract: A micro-calorimeter apparatus comprises a thermostated housing (3,4,5); a pair of essentially flat heat sinks (9,10), suspended in the housing (2) and thermally floating relative to the environment inside the housing (3,4,5). The heat sinks (9,10) are arranged with their surfaces facing each other. A pair of Peltier elements (11) are thermally attached to the heat sinks (9,10), one element (11) on each heat sink (9,10), on the facing surfaces, forming a gap between them for the accommodation of a generally flat biosensor unit (12).Type: GrantFiled: July 23, 2001Date of Patent: September 11, 2012Assignee: Senzime AB (Publ.)Inventors: Thomas Carlsson, Kjell Rosengren
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Patent number: 8252249Abstract: A biochemical chip in which at least the inner surface of a flow path is covered with a chemisorption monomolecular film having arbitrary surface energy, and the method includes: a step for pre-forming a chemisorption monomolecular film having arbitrary surface energy on the inner surfaces of flow path parts of first and second members which are processed to have flow paths; and a step for facing and bonding the first and second members.Type: GrantFiled: April 12, 2007Date of Patent: August 28, 2012Inventor: Kazufumi Ogawa
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Patent number: 8252594Abstract: A composition containing a petroleum hydrocarbon, a biodiesel fuel or an ethanol fuel, and an organic marker compound.Type: GrantFiled: November 15, 2010Date of Patent: August 28, 2012Assignee: Rohm and Haas CompanyInventors: Rajiv Manohar Banavali, Randall Wayne Stephens
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Patent number: 8246918Abstract: Polymer compositions and articles formed therefrom are described herein. The compositions include a random copolymer and a radiation additive, wherein the random copolymer includes propylene and less than 2 wt. % ethylene and exhibits a melt flow rate of from about 30 to 100 dg/min., the polymer composition exhibits a flexural modulus of from about 160 kpsi to about 200 kpsi and the polymer composition is adapted to produce a polymer article exhibiting low plate out, a haze at 20 mils of no greater than 15%, radiation stability and autoclavability.Type: GrantFiled: October 19, 2009Date of Patent: August 21, 2012Assignee: Fina Technology, Inc.Inventors: Margarito Lopez, Michael Musgrave
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Patent number: 8246920Abstract: The present invention provides a method for reducing reagent usage, comprising the steps of providing a retainer, at least one group of loopholes being provided on the sidewalls of the retainer; providing a colorimetric glass, adapted to be inserted into the retainer, for receiving the first reagent to be observed through said loopholes; providing a cap, for capping the colorimetric glass and the retainer into a whole, after the colorimetric glass being inserted into the retainer. The present invention mainly uses a reagent tube with a retainer having a new structure, a colorimetric glass and a cap, storing the first reagent only in the colorimetric glass, and the volume of the colorimetric glass is far less than that of the current reagent tube, thus the usage of the reagents can be reduced effectively.Type: GrantFiled: July 15, 2009Date of Patent: August 21, 2012Assignee: Beijing Strong Biotechnologies, Inc.Inventors: Ziyuan Yu, Jin Shao
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Patent number: 8246919Abstract: A rack for a plurality of capped tubes, including a frame having a longitudinally extending bottom base member having a row of spaced open top recesses adapted to receive the capped tubes. Vertical supports at the ends of the row of recesses fix a cover member above the base member. The cover member has openings therethrough smaller than the capped tubes. A wall is along one longitudinal side between the base member and the cover member, with the other longitudinal side between the base member and the cover member being open. Support fingers extend horizontally from the wall toward the open longitudinal side and are vertically aligned between the recesses to secure capped tubes in a generally vertical direction in a longitudinally extending vertical plane. The base member and cover member are vertically spaced a distance sufficient to permit tipped capped tubes to be moved into the frame with the tipped tubes then dropped into the recesses and tipped back to an upright vertical position.Type: GrantFiled: September 21, 2006Date of Patent: August 21, 2012Assignee: Abbott LaboratoriesInventors: Stephen L. Herchenbach, E. Kim Pavlovic