Patents Examined by Paul J. Killos
  • Process for the preparation of 2-methyl-1,3-dicarboxylates
    Patent number: 6417391
    Abstract: A process for the preparation of a 2-methyl-1,3-dicarboxylate by reaction of a 1,3-dicarboxylate with formaldehyde and hydrogen, where, based on 1 mol of dicarboxylate, from 1.0 to 2.0 mol of formaldehyde are used, and either the reaction mixture or 2-hydroxymethyl-2-methyl-1,3-dicarboxylate isolated therefrom as by-product are subjected to thermolysis at temperatures of from 50° C. to 300° C.
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: July 9, 2002
    Assignee: Degussa AG
    Inventor: Frank Bauer
  • Process for preparing methionine
    Patent number: 6417395
    Abstract: The invention concerns a method for preparing methionine aminoamide. The invention also concerns the preparation of methionine without co-production of salts, from an aqueous solution containing essentially methionine aminonitrile by producing during a first step aminoamide followed by two complementary steps.
    Type: Grant
    Filed: July 12, 2001
    Date of Patent: July 9, 2002
    Assignee: Aventis Animal Nutrition S.A.
    Inventors: Hervé Ponceblanc, Olivier Favre-Bulle, Georges Gros
  • Specific salt forms of triphenylethylene derivatives as selective estrogen receptor modulators
    Patent number: 6417394
    Abstract: This invention pertains to novel salt forms of trophenylethylene compound, such as 3-[4(1,2-diphenyl-but-1-enyl)-phenyl]-acrylic acid, as selective estrogen receptor modulators. This invention also provides methods for the treatment and/or prevention of breast, uterine, ovarian, prostrate and colon cancer, osteoporosis, cardiovascular disease, and benign proliferative disorders, as well as pharmaceutical compositions of the compounds of the present invention.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: July 9, 2002
    Assignee: Bristol Myers Squibb Pharma Company
    Inventors: Gary A. Cain, Reginald O. Cann, Christopher A. Teleha, Denette K. Murphy
  • Process for producing polyarylate
    Patent number: 6417291
    Abstract: In a process for producing a polyarylate through the polycondensation of an aromatic dihydroxy compound and an aromatic ester bond forming precursor, a salicylic acid ester compound having a specific structure is used as a terminal modifying agent. In a process for producing a polyarylate through the polycondensation of an aromatic dihydroxy compound and an ester bond forming aromatic dicarboxylic acid derivative, a polyarylate of high-molecular weight having excellent color tone and hue stability is obtained.
    Type: Grant
    Filed: December 19, 2000
    Date of Patent: July 9, 2002
    Assignee: Teijin Limited
    Inventors: Hiroaki Kaneko, Wataru Funakoshi, Yuichi Kageyama, Katsushi Sasaki
  • Method for handling waste oil
    Patent number: 6414183
    Abstract: The present invention provides a method for stabilizing waste oil which is taken of each chemical apparatus of the manufacturing line of (meth)acryl acid and/or ester thereof, and treating the waste oil such as draining it out of the production apparatus, for example, a distillation tower from its bottom, sending and transporting it by a pump through a pipeline, and storing it in a storage tank in a simple manner while keeping the waste oil in a stable state. The waste oil can be stabilized by coexisting with solvent. The solvent used in the present invention is typically at least one selected from the group consisting of water, alcohol, ether, carboxylic acid, ketone, aromatic hydrocarbons, and aliphatic hydrocarbons.
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: July 2, 2002
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Kazuhiko Sakamoto, Sei Nakahara, Masatoshi Ueoka
  • Process of producing cyclopropanecarboxylate compounds
    Patent number: 6414181
    Abstract: Provided are processes of producing a cyclopropanecarboxylate compound of Formula (I): The processes comprise reacting a cyclopropanecarbaldehyde compound of Formula (II): with a dicarboxylate compound of Formula (III): in the presence of at least one secondary amine from among piperidine, morpholine, pyrrolidine, diethylamine or N-methylethanolamine.
    Type: Grant
    Filed: January 5, 2000
    Date of Patent: July 2, 2002
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Takashi Furukawa, Noritada Matsuo
  • Production process for hydroxyalkyl ester
    Patent number: 6414182
    Abstract: The present invention provide a production process for a hydroxyalkyl ester which comprises the step of carrying out a reaction between a carboxylic acid and an alkylene oxide in the presence of a catalyst, wherein the production process sufficiently enhances the conversion or selectivity in the reaction. The production process is characterized in that the reaction is carried out in a reaction liquid under conditions where a relationship a<b is kept throughout the reaction wherein “a” is a molar concentration (mol %) of the carboxylic acid in the reaction liquid and wherein “b” is a molar concentration (mol %) of the alkylene oxide in the reaction liquid.
    Type: Grant
    Filed: July 22, 2000
    Date of Patent: July 2, 2002
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Yasuhiro Shingai, Tokumasa Ishida, Fumio Shibusawa, Tetsuya Kajihara, Yukihiro Yoneda, Hajime Matsumoto, Masatoshi Ueoka
  • Bisoximether derivatives, methods and intermediate products for the production thereof, and their use for combating fungicidal pests and animal pests
    Patent number: 6414031
    Abstract: There are disclosed bisoxime ether derivatives of the formula I in which the variables have the following meanings: R1 is halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy or C1-C4-haloalkoxy; n is 1 to 5, it being possible for the radicals R1 to be different if n is other than 1; R2 is C1-C4-alkyl, C3-C6-alkenyl or C3-C6-alkynyl, it being possible for these groups to be partially or fully halogenated; Q is C(═CHOCH3)—COOCH3, C(═CHCH3)—COOCH3, C(═NOCH3)—COOCH3 or C(═NOCH3)13 CONHCH3; and salts thereof, processes and intermediates for the preparation of these compounds, and their use for controlling animal pests and harmful fungi.
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: July 2, 2002
    Assignee: BASF Aktiengesellschaft
    Inventors: Herbert Bayer, Roland Götz, Michael Keil, Hubert Sauter, Oliver Cullmann, Markus Gewehr, Wassilios Grammenos, Andreas Gypser, Bernd Müller, Arne Ptock, Eberhard Ammermann, Thomas Grote, Gisela Lorenz, Siegfried Strathmann, Volker Harries
  • Preparation of cationic surfactants containing ester group in molecules
    Patent number: 6414170
    Abstract: The present invention relates to a method for preparing a cationic surfactant in which physical chemical characteristics such as softness, antistatic properties, etc. as well as biodegradability are quite excellent due to having an ester group and a hydrophilic hydroxyl group in its molecules. A cationic surfactant of the present invention is prepared by reacting tertiary amine drivatives, fatty acid, and epihalohydrin, and prepared simply by reacting esterification and quaternary reactions in one step with a high yield. The above cationic surfactant is a high grade alkyl quaternary ammonium compound as represented in General Formula (1), wherein R1 is a C1-C4 alkyl group; R2 is a C7-C21 linear or branched alkyl or alkenyl group; A is OCOR3, NHCOR3 or OH; R3 is a C7-C21 linear or branched alkyl or alkenyl group; X is a halogen atom; and n is an integral number from 2 to 6.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: July 2, 2002
    Assignee: LG Chemical Ltd.
    Inventors: Dong-Il Kim, Jeong-Wook Ha, Tae-Seong Kim, Moon-Jeong Rang
  • Crystals of [S,S]-ethylenediamine-N,N?-disuccinic acid with high bulk density and method of obtaining the same
    Patent number: 6414189
    Abstract: Crystals of [S,S]-ethylenediamine-N,N′-disuccinic acid which have a bulk density of 0.45 to 1.2 g/cm3, and a process for obtaining these crystals comprising the steps of adjusting an aqueous solution of an [S,S]-ethylenediamine-N,N′-disuccinic acid metal salt to a temperature of 40 to 80° C. and a pH of 1.9 to 4.5, and cooling the solution to a temperature below 40° C. over a period of 0.2 to 10 hours while supplying a mineral acid so as to maintain the pH at 1.9 to 4.5 to precipitate [S,S]-ethylenediamine-N,N′-disuccinic acid in a high yield.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: July 2, 2002
    Assignee: Mitsubishi Rayon Co., Ltd.
    Inventors: Hiroyasu Banba, Shigeho Tanaka, Kiyonobu Niwa, Takakazu Endo
  • Alpha-and beta-substituted trifluoromethyl ketones as phospholipase inhibitors
    Patent number: 6414179
    Abstract: Inhibitors of the cytosolic phospholipase A2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula where X, Z, R1, R2, R3, R4, Ra and Rb are as defined in the specification.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: July 2, 2002
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jacques Banville, Anne Marinier, Yonghua Gai, Serge Plamondon, Stephan Roy, Neelakantan Balasubramanian
  • 3,7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure
    Patent number: 6410591
    Abstract: The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma a therapeutically effective amount of a 3, 7 or 3 and 7 thia or oxa prostanoic acid derivative.
    Type: Grant
    Filed: May 8, 2001
    Date of Patent: June 25, 2002
    Assignee: Allergan Sales, Inc.
    Inventors: Robert M. Burk, Mark Holoboski, Mari F. Posner
  • Salicylic acid ester derivative and its production
    Patent number: 6410777
    Abstract: The present invention provides a salicylic acid ester derivative having an impurity content lower than a specific level and expressed by the following formula (1) (in the formula, R1 is methyl group or ethyl group, R2, which may be substituted optionally, is an alkyl group having a carbon number of from 1 to 30, alkoxy group having a carbon number of from 1 to 30, aryl group having a carbon number of from 6 to 30, aryloxy group having a carbon number of from 6 to 30, aralkyl group having a carbon number of from 6 to 30 or aralkyloxy group having a carbon number of from 6 to 30). The salicylic acid ester derivative is effective as a terminal blocking agent or a polymerization. promoting agent for a polycarbonate, and gives a polycarbonate having good color tone and suitable for optical material use.
    Type: Grant
    Filed: October 4, 1999
    Date of Patent: June 25, 2002
    Assignee: Teijin Limited
    Inventors: Hiroaki Kaneko, Wataru Funakoshi, Katsushi Sasaki
  • Recovery of metal components of a catalyst in a process for production of trimellitic acid
    Patent number: 6410784
    Abstract: A process for recovering cobalt and manganese components from a product stream or a residue stream that resulted from a process which employs a catalyst system containing the cobalt and manganese components for oxidizing pseudocumene to trimellitic acid includes the steps of adding a precipitating agent to the product stream or the residue stream in an effective amount to react with the cobalt and manganese components in the product stream or the residue stream.
    Type: Grant
    Filed: April 16, 2001
    Date of Patent: June 25, 2002
    Assignee: Chinese Petroleum Corporation
    Inventors: Hsi-Yen Hsu, Ching-Tang Lin
  • Method for producing resols
    Patent number: 6410776
    Abstract: The invention relates to a process for the preparation of resols by reacting phenolic compounds with aldehydes with catalysis by metal salts whose cation can easily be precipitated as low-solubility salts in industrial processes. In this process, a dispersant is added to the reaction mixture comprising phenolic compound, aldehyde and metal salt before, during or after the condensation reaction, and a complexing agent is admixed after the condensation reaction is complete and after the dispersant has been admixed. The resultant resins are transparent even after neutralization using sulphuric acid.
    Type: Grant
    Filed: October 4, 2000
    Date of Patent: June 25, 2002
    Assignee: Bakelite AG
    Inventors: Willi Roll, Axel Bottcher, Walter Napp, Peter Fricke
  • Sulfonic acid ester derivatives, method for production thereof and use thereof
    Patent number: 6410773
    Abstract: Novel and useful optical active 2-aralkyl-3-sulfonyloxy-1-propanol and 2-aralkyl-3-sulfonyloxypropionic acid are provided by using an optical active 2-aralkyl-3-acyloxy-1-propanol as a starting material. Furthermore, an optical active 2-aralkyl-3-thiopropionic acid, which is an important intermediate of enkephalinase inhibitor, is provided. According to the present invention, industrially useful optical active sulfonic acid ester derivatives can be provided.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: June 25, 2002
    Assignee: Kaneka Corporation
    Inventors: Yoshihiko Yasohara, Kenji Miyamoto, Shigeru Kawano, Junzo Hasegawa
  • Method of producing carboxylic acid salts
    Patent number: 6410783
    Abstract: The present invention is a method of producing dry, alkali metal or ammonium carboxylic acid salt particles. In accordance with the invention, a molten carboxylic acid is mixed with a solution of an alkali metal-containing or ammonium-containing alkaline compound and the carboxylic acid and alkaline compound are reacted to form the carboxylic acid salt. Water is then removed from the carboxylic acid salt to produce dry, carboxylic acid salt particles. The feed ratio of the molten carboxylic acid and the alkaline compound is controlled to neutralize the carboxylic acid in the process.
    Type: Grant
    Filed: October 19, 2000
    Date of Patent: June 25, 2002
    Assignee: BASF Corporation
    Inventors: Rodger E. Peterson, Terrance M. Cannan, Rudolph E. Lisa
  • Composition and method for preparing electrically neutral amino acid chelates free of interfering ions
    Patent number: 6407138
    Abstract: The present invention relates to compositions and methods of preparing amino acid chelates that are electrically neutral and free of interfering ions. The composition is prepared by reacting in an aqueous solution a calcium oxide and/or hydroxide, an amino acid, and a soluble metal sulfate salt at a ratio sufficient to allow substantially all of the ions present in solution to react forming a metal amino acid chelate and an essentially inert calcium sulfate, and wherein the metal amino acid chelate has a ligand to metal molar ratio from 2:1 to 3:1.
    Type: Grant
    Filed: October 11, 2000
    Date of Patent: June 18, 2002
    Assignee: Albion International, Inc.
    Inventors: Stephen D. Ashmead, David C. Wheelwright, Clayton Ericson, Mark Pedersen
  • Process for recovering hydrogen in producing pure terephthalic acid
    Patent number: 6407286
    Abstract: A method for recovering and recycling excess hydrogen from process vent streams in the production of highly pure terephthalic acid where the production of the pure terephthalic acid comprises catalytically hydrogenating impure terephthalic acid, which typically contains 4-carboxybenzaldehyde (4-CBA), color bodies and other impurities, in aqueous liquid phase solution at elevated temperature and pressure.
    Type: Grant
    Filed: January 14, 2000
    Date of Patent: June 18, 2002
    Inventors: David Parker, Fiona Mary Campbell, Andrew Harrison
  • Process for the production of vinyl acetate
    Patent number: 6407283
    Abstract: A process for the production of vinyl acetate which comprises contacting ethylene, acetic acid and an oxygen-containing gas with a supported palladium catalyst prepared by a process comprising the steps of (a) impregnating a catalyst support with a palladium compound, (b) converting the palladium compound to substantially metallic palladium, and (c) sintering the supported palladium at a temperature of greater than 500° C.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: June 18, 2002
    Assignee: BP Chemicals Limited
    Inventors: John William Couves, Simon James Kitchen