Patents Examined by Philip R Wiest
  • Patent number: 10799423
    Abstract: A liquid-transfer adapter operatively interposable between an injector and a vial is provided. The liquid-transfer has an injector engaging portion configured for fluidly coupling to an injector and a vial coupling. The vial coupling includes a spike that has a spike axis and a tip portion configured for piercing a septum of a vial. The tip portion includes a plurality of facets that meet each other at one or more edges and at least one of the one or more edges is sloped with respect to the spike axis. The spike defines a channel extending therethrough in fluid communication with the injector engaging portion. A channel opening is defined in at least one of the facets and disposed without interrupting the edges.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: October 13, 2020
    Assignee: FERRING INTERNATIONAL CENTER S.A.
    Inventors: Julius C. Sund, Kevin D. Swanson
  • Patent number: 10792480
    Abstract: Systems and methods for flushing shunt systems are disclosed herein. In some embodiments, a flusher includes a pinch tube that extends over a flush dome such that a user can simultaneously close the pinch tube and actuate the flush dome with a single motion. Flushing and refill valves of the system can be disposed in a cartridge that is laterally-offset from the flush dome, advantageously reducing the height profile of the flusher. Flushers with integrated shunt valves are also disclosed, as are shunt systems with restricted and unrestricted modes for selectively limiting the instances in which a user can open an auxiliary flow path through the system.
    Type: Grant
    Filed: October 12, 2017
    Date of Patent: October 6, 2020
    Assignee: Anuncia, Inc.
    Inventors: P J Anand, Deep Arjun Singh, Greg Eberl, Andrew East, Morgan Brophy, Ayesha Arzumand, Stela Moura, Loredana Guseila
  • Patent number: 10792412
    Abstract: A method for venting a dialyzer which has a dialyzate chamber, a blood chamber and a semi-permeable dialyzer membrane separating these two chambers. An overpressure is generated in the dialyzate chamber with respect to the blood chamber for removing air inclusions lying at the surface of the membrane at the dialyzate chamber side after a filling of the dialyzate chamber and before a filling of the blood chamber.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: October 6, 2020
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Peter Kloeffel, Thomas Nuernberger
  • Patent number: 10786430
    Abstract: The disclosure relates to a medicament delivery device, comprising a medicament cartridge adapted to contain a medicament and a stopper slidably arranged within the cartridge. The stopper-comprises a rigid body that is enclosed partially by a soft sealing component.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: September 29, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Schabbach, Daniel Auernhammer, Christoph Dette
  • Patent number: 10773012
    Abstract: According to some embodiments, a system may treat blood outside the body of a patient. The system may include one or more pumps configured to draw blood from a patient into a fluid flow path at a rate, for example, of 5-7 liters per minute. The system may include one or more heat exchangers coupled to the fluid flow path and configured to heat the blood, for example, to a temperature above 42 degrees Celsius and below 43.2 degrees Celsius.
    Type: Grant
    Filed: February 16, 2015
    Date of Patent: September 15, 2020
    Assignee: Humanity Life Extension LLC
    Inventor: Patrick Richard Spearman
  • Patent number: 10765845
    Abstract: A medical tube 10 (drain tube 10) includes a main shaft tube 20, a flow path opening/closing mechanism 40, and a branch tube 30. The main shaft tube 20 internally has a main shaft side distal opening 21a and a main shaft lumen 21. The flow path opening/closing mechanism 40 brings the main shaft lumen 21 into a communicating state by applying pressure smaller than predetermined pressure, and brings the main shaft lumen 21 into a blocked state by applying pressure equal to or greater than the predetermined pressure. The branch tube 30 promotes a pancreatic juice pj to flow into a branch lumen 31, based on the applied pressure which is equal to or greater than the predetermined pressure.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: September 8, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Naoki Aramaki, Yuuki Souma
  • Patent number: 10765846
    Abstract: Methods for treating hydrocephalus using a shunt, the shunt having one or more CSF intake openings in a distal portion, a valve disposed in a proximal portion of the shunt, and a lumen extending between the one or more CSF intake openings and the valve, the method comprises deploying the shunt in a body of a patient so that the distal portion of the shunt is at least partially disposed within a CP angle cistern, a body of the shunt is at least partially disposed within an IPS of the patient, and the proximal portion of the shunt is at least partially disposed within or proximate to a JV of the patient, wherein, after deployment of the shunt, CSF flows from the CP angle cistern to the JV via the shunt lumen at a flow rate in a range of 5 ml per hour to 15 ml per hour.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: September 8, 2020
    Assignee: CereVasc, Inc.
    Inventors: Carl Heilman, Adel M. Malek, David A. Rezac, Timothy W. Robinson, Joseph Ting
  • Patent number: 10758718
    Abstract: Systems and methods for implanting an endovascular shunt in a patient is disclosed. The system having an expandable anchor configured for being deployed in a dural venous sinus of a patient at a location distal to a curved portion of a wall of an inferior petrosal sinus (IPS) of the patient; an elongate guide member coupled to, and extending proximally from, the anchor; a shunt delivery catheter having a first lumen configured to receive the guide member, and a second lumen extending between respective proximal and distal openings in the shunt delivery catheter, the shunt delivery catheter further having a penetrating element coupled to a distal end of the catheter; and the system further having a guard at least partially disposed over, and movable relative to, the penetrating element.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: September 1, 2020
    Assignee: CereVasc, Inc.
    Inventors: Adel M. Malek, Carl Heilman, David A. Rezac, Jack B. Sattell, Anthony Maiorano
  • Patent number: 10758657
    Abstract: An artificial lung is provided that includes a plurality of porous hollow fiber membranes for gas exchange comprising a hydrophobic polymer material, wherein the hollow fiber membranes have inner surfaces forming lumens and outer surfaces, and wherein at least one of the inner surfaces or the outer surfaces is coated with a polymer-containing solution that has a surface tension of 40 to 55 dyn/cm and that contains a solvent and a polymer having a structural unit represented by Formula (I): wherein in Formula (I), R3 represents a hydrogen atom or a methyl group, R1 represents an alkylene group having 1 to 4 carbon atoms, and R2 represents an alkyl group having 1 to 4 carbon atoms.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: September 1, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Takao Anzai, Eisuke Sasaki, Norikazu Ishida
  • Patent number: 10758656
    Abstract: The present invention relates to a dialysis machine having a hydraulic system that is intended for providing a dialysis solution or an element of the dialysis solution, wherein the hydraulic system has a degassing pump for degassing the dialysis solution or an element of the dialysis solution, and having a pneumatic system in which a vacuum is present at least at times for operating a component of the dialysis machine, wherein there is a connection line between the suction side of the degassing pump and the pneumatic system for a vacuum generation in the pneumatic system.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: September 1, 2020
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Ralf Mueller, Soeren Gronau
  • Patent number: 10758658
    Abstract: An artificial lung is provided having a plurality of porous hollow fiber membranes for gas exchange, in which the hollow fiber membranes have outer surfaces, inner surfaces forming lumens, and opening portions through which the outer surfaces communicate with the inner surfaces, any one of the outer surfaces and the inner surfaces is coated with a colloidal solution of an antithrombotic material containing a polymer as a main component, and an average particle size of the colloid is at least 1.5 times a diameter of the opening portions of the hollow fiber membranes. An artificial lung is provided that can effectively suppress leakage of blood plasma components after blood circulation (blood plasma leakage).
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: September 1, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Takao Anzai, Takayuki Kido
  • Patent number: 10751462
    Abstract: A medical apparatus in which the measurement of an electrocardiogram and the detection of blood leakage that may occur if an accessing unit comes off the patient can be performed accurately without fail, and with which the efficiency in the operation to be performed before the treatment can be improved. A medical apparatus includes a blood purification device including an accessing unit formed of a venous puncture needle stickable into a patient, electrocardiogram-measuring devices closely attached to a skin of the patient and being capable of measuring an electrocardiogram of the patient, and a blood-leakage-detecting device attached to a position near the accessing unit and being capable of detecting blood of the patient that may leak from the accessing unit. The medical apparatus further includes an integrated detecting device provided as a unit including the electrocardiogram-measuring device and the blood-leakage-detecting device.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: August 25, 2020
    Assignee: Nikkiso Company Limited
    Inventors: Hitoshi Goto, Masahiro Toyoda, Tomoya Murakami, Shigeaki Funamura
  • Patent number: 10744258
    Abstract: A whole blood treatment device includes a first conduit, a second conduit, and a rotating or reciprocating element having a channel. The first and second conduits are fluidly coupled to the rotating or reciprocating element such that the channel is fluidly continuous with the first conduit when the channel is fluidly discontinuous with the second conduit, and such that the channel is fluidly discontinuous with the first conduit when the channel is fluidly continuous with the second conduit. The first conduit is configured to receive whole blood, and the second conduit is configured to receive a regeneration fluid. The channel comprises a surface that is modified with an affinity agent at a concentration effective to allow removal of a target compound from whole blood.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: August 18, 2020
    Assignee: Qualigen Inc.
    Inventor: Michael Poirier
  • Patent number: 10736818
    Abstract: A transfer member (128) comprising a housing (24) having a top, a side wall (26), an open bottom, the open bottom permitting insertion of a vial (12) within the housing, a piercing member (34) mounted within the housing (24), the piercing member (34) having a piercing tip (36) located at a bottom end thereof, the piercing member having an interior passageway formed therein, a connector (30) located on an exterior side of the top, a moveable member (40) mounted within the housing (24), the moveable member (40) being moveable from a first position wherein the moveable member (40) prevents access to the piercing tip (36) to a second position permitting access to the piercing tip when the vial is inserted in the housing, a transfer member (128), the transfer member (128) having first and second transfer member ends (131, 133) wherein the moveable member (40) and the housing (24) cause the moveable member (40) to rotate when the moveable member (40) moves upwardly upon insertion of the vial (12), the moveable memb
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: August 11, 2020
    Assignee: Duoject Medical Systems Inc.
    Inventors: Yan Tremblay, Mathieu Viens
  • Patent number: 10737010
    Abstract: In one aspect, an arteriovenous access valve system may generally include a first valve configured to be positioned at or adjacent to an end of arteriovenous graft and a second valve configured to be positioned at or adjacent to an opposite end of the arteriovenous graft. In addition, the system may include an actuator assembly in fluid communication with the first and second valves. The actuator assembly may include a housing, a driver assembly positioned within the housing and a drive magnet positioned within the housing. The drive magnet may be rotatably coupled to the driver assembly such that, when the drive magnet is rotated, the driver assembly is configured to be rotatably driven so as to supply fluid to the first and second valves or to draw fluid out of the first and second valves depending on a rotational direction of the driver assembly.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: August 11, 2020
    Assignee: DIAXAMED, LLC
    Inventors: James S. Johnson, Frank V. Patterson, Jordan Jacobs
  • Patent number: 10736764
    Abstract: A gastric implant includes a distal sleeve portion configured to be disposed in a duodenum of a patient, and a pyloric restriction portion connected to a proximal end of the distal sleeve portion. The pyloric restriction portion is configured to be disposed in a pylorus of a patient. Also, the implant includes a proximal anchor portion connected to a proximal end of the pyloric restriction portion. The proximal anchor portion is configured to be disposed in a lower stomach of the patient. The proximal anchor portion has at least one eyelet for fastening to the stomach to secure the implant to the gastrointestinal tract.
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: August 11, 2020
    Assignee: Apollo Endosurgery US, Inc.
    Inventors: Charles Dean, Donald K. Jones
  • Patent number: 10736778
    Abstract: Devices can be implanted in an eye to treat glaucoma. The devices described herein include a body defining a lumen and having first and second ends and external and lumenal surfaces. The body has a length sufficient to provide fluid communication between the anterior chamber and tear film of the eye through the lumen when the device is implanted in the sclera. By the strategic selection of particular materials of construction, and/or by controlling the configuration and size of the lumen, in some embodiments, the device is a filterless construct. In some embodiments, a filter is included. The glaucoma treatment devices as provided herein are designed to prevent bacterial ingress and to provide the required level of outflow resistance to achieve a desired intraocular pressure. Methods of treating glaucoma wherein the device is implanted in the sclera of an afflicted eye are also described.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: August 11, 2020
    Assignee: MicroOptx Inc.
    Inventor: J. David Brown
  • Patent number: 10709827
    Abstract: A substance exchange device for intracorporal use includes a cavity for receiving blood having at least one blood inlet and at least one blood outlet, a substance exchange membrane adjoining the cavity, a supply duct for supplying an exchange fluid to the substance exchange membrane, a blood pump arranged within the cavity and a drive unit for the blood pump. The blood pump is configured to pump blood in a direction from a blood inlet to a blood outlet of the cavity. The drive unit includes a turbine, which is connected to the supply duct and may be driven by an exchange fluid supplied via the supply duct, where the turbine includes at least a rotor coupled to the blood pump and a stator (turbine nozzle) arranged upstream of the rotor.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: July 14, 2020
    Assignee: TECHNISCHE UNIVERSITÄT WIEN
    Inventors: Christoph Janeczek, Margit Gföhler, Michael Harasek
  • Patent number: 10709832
    Abstract: Interventional procedures on the carotid arteries are performed through a transcervical access while retrograde blood flow is established from the internal carotid artery to a venous or external location. A system for use in accessing and treating a carotid artery includes an arterial access device, a shunt fluidly connected to the arterial access device, and a flow control assembly coupled to the shunt and adapted to regulate blood flow through the shunt between at least a first blood flow state and at least a second blood flow state. The flow control assembly includes one or more components that interact with the blood flow through the shunt.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: July 14, 2020
    Assignee: Silk Road Medical, Inc.
    Inventors: Enrique Criado, Tony M. Chou, Michi E. Garrison, Gregory M. Hyde, Alan Schaer, Richard Renati
  • Patent number: 10709837
    Abstract: An infusion set employing a spike cap, arranged at which there is an opening configured to prevent passage therethrough of solid or liquid but to allow passage therethrough of gas at interior of the cap, hydrophobic filter being arranged at a location inward from where a tip of spike is inserted at interior of the cap by way of an insertion port, and a lid exterior of the opening for closing the opening; and in which there are hook(s) for anchoring to infusion tubing and a clip equipped with a catch for a flange arranged at the spike. Employing the cap at the infusion set makes it possible to carry out preprocessing including priming and backpriming by a simple operation without leakage of liquid.
    Type: Grant
    Filed: February 9, 2015
    Date of Patent: July 14, 2020
    Assignee: KOBAYASHI & CO., LTD.
    Inventors: Koji Fukuoka, Go Kawaoi, Kazuyuki Osawa, Imari Endo