Patents Examined by Philip R Wiest
  • Patent number: 11185620
    Abstract: Provided is a blood purifying apparatus including a blood purifying filter in which mass transfer occurs between blood and dialysis fluid, a blood tube connecting the blood purifying filter and a patient to allow blood to flow therethrough, a dialysis fluid supply tube connected to the blood purifying filter and allowing dialysis fluid to be supplied to the blood purifying filter therethrough, a dialysis fluid discharge tube connected to the blood purifying filter and allowing dialysis fluid to be discharged from the blood purifying filter therethrough; and a fluid pumping device. The fluid pumping device further includes a plurality of chamber each having an internal space, a chamber pressurizing member disposed inside the plurality of chambers and compressing or expanding the chambers to thereby allow a fluid to flow therethrough, and a flow controller controlling a flow passage.
    Type: Grant
    Filed: September 17, 2019
    Date of Patent: November 30, 2021
    Assignee: Exorenal Inc.
    Inventor: Jake K Lee
  • Patent number: 11179550
    Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: November 23, 2021
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 11179551
    Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: November 23, 2021
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 11179552
    Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: November 23, 2021
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 11173289
    Abstract: An implantable body fluid drainage system includes a metering shunt having a housing with an internal chamber. A movable barrier divides the chamber into a first section and a second section, and the barrier can be displaced by a differential pressure. A first powered inlet valve providing a fill path to the first section of the chamber, and a first powered drain valve providing a drain path from the first section of the chamber. A CSF inlet conduit connects a CSF space to the first powered inlet valve. A CSF outlet conduit connects the first powered outlet valve to a discharge location. A controller opens the first powered inlet valve and close the first powered drain valve to fill the first section to a volume defined by the barrier and chamber geometry and closes the first powered inlet valve and opens the first powered drain valve to discharge the filled volume from the first section through the outlet conduit.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: November 16, 2021
    Assignee: CSF Refresh, Inc.
    Inventors: Tom Saul, Kristof Hovaten
  • Patent number: 11160911
    Abstract: A portable device for removal of metabolic waste from the blood of patient having kidney disease or in need of hemodialysis is provided. Methods of hemodialysis employing the portable device beneficially obtain a dialysate by electrokinetic means from excess fluid in the peripheral blood of the patient in need thereof. The methods employ a branched microfluidic channel for the use of ion concentration polarization to separate charged from neutral species in blood to obtain the dialysate for undergoing hemodialysis. Beneficially the methods and device are resistant to biofouling, remove the need for a dialysate and/or dialysate reservoir, and provide a disposable, wearable device.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: November 2, 2021
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Robbyn K. Anand, Beatrise Berzina
  • Patent number: 11154704
    Abstract: A system for drawing blood from a heart of a patient, includes a blood pump, an outflow cannula and a flexible cannula assembly. The cannula assembly further includes a flexible cannula body including a proximal end, a distal end, an inner wall defining a lumen, and an outer wall. A tip is coupled with the distal end of the cannula body, and an anchor is coupled to the tip. The anchor is configured to engage an internal structure of the heart and resists movement of the cannula assembly in at least one direction along the flexible cannula body. A ring member is configured to be coupled to the heart wall and is positioned at least partially around the outer wall of the cannula body proximally relative to the tip. The ring member is further configured to provide hemostasis between the heart wall and the cannula body.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: October 26, 2021
    Assignee: CircuLite, Inc.
    Inventors: Robert C. Farnan, Robert G. Hudgins, John Dockter
  • Patent number: 11154695
    Abstract: An apparatus (10) for minimally-invasive, including non-invasive, prevention and/or treatment of hydrocephalus and method for use of the same are disclosed. In one embodiment of the apparatus (10), a housing (50) is sized for superjacent contact with a skull having a fontanel. Within the housing (50), a compartment (12) includes a pressure applicator (88), such as a fluid-filled bladder (22), under the control of a pressure regulator (14). The pressure applicator (88) is configured to selectively apply an external pressure to the fontanel. The compartment (12) includes a pressure sensor (90) configured to measure intracranial pulse pressure of the fontanel. Further, in one embodiment, the apparatus (10) can cause pulse pressure modulation by adjusting the intracranial pulse pressure via the pressure applicator (88). This enables a non-invasive measurement of the pulse pressure and modulation thereof in infants, for example.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: October 26, 2021
    Inventor: Frederick H. Sklar
  • Patent number: 11147907
    Abstract: According to some embodiments, a system may treat blood outside the body of a patient. The system may include one or more pumps configured to pump blood in a fluid flow path at a collective rate over 4 liters per minute. The system may include one or more heat exchangers operable to heat at least a portion of the blood to a temperature of at least 42 degrees Celsius and to allow the blood to cool one or more degrees following heating. The system may include one or more albumin dialysis modules configured to perform albumin dialysis on at least a portion of the blood at least after the one or more heat exchangers allow the blood to cool one or more degrees.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: October 19, 2021
    Assignee: Humanity Life Extension LLC
    Inventor: Patrick Richard Spearman
  • Patent number: 11141312
    Abstract: This document discusses, among other things, an apparatus comprising a lacrimal implant insertable at least partially into a lacrimal punctum. The lacrimal implant comprises an implant core, and an implant body. The implant body includes a cavity sized and shaped to receive the implant core. At least one of the implant core and the implant cavity includes a detection device configured to allow automatic detection of the lacrimal implant with a separate detector device.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: October 12, 2021
    Assignee: Mati Therapeutics Inc.
    Inventors: Eugene de Juan, Jr., Stephen Boyd, Cary J. Reich, Christopher V. Cardenas, Tommy Jewell, Lorrie Ma, Tuan Nguyen
  • Patent number: 11141516
    Abstract: The invention relates to a portable gas exchange device for gas exchange of at least one gas from a liquid to a fluid. The gas exchange device comprises a first gas exchange section, for passage of a fluid, and a second gas exchange section for passage of a liquid enriched with a first gas, wherein the fluid has a lower concentration of the first gas than the liquid. A pumping system for transporting a first fluid with a lower concentration of a first gas in the first gas exchange section, in particular in a first fluid circuit, is also configured in the gas exchange device. In a mixing chamber configured in the gas exchange device, the first gas exchange section and the second gas exchange section adjoin one another via a wall designed such that at least the first gas can pass through. A housing serves as the common receptacle at least of the pumping system and the mixing chamber.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: October 12, 2021
    Assignee: Novalung GmbH
    Inventors: Georg Matheis, Tatjana Thumm, Michael Hildebrand, Nektarios Panagias, Dirk Stingel, Reinhold Beuter
  • Patent number: 11141517
    Abstract: An oxygenator apparatus for use in an extracorporeal circuit. The apparatus includes a housing and a membrane assembly disposed within the housing. The membrane assembly includes a first plurality of gas exchange elements disposed in a first zone and a second plurality of gas exchange elements disposed in a second zone. The second zone is arranged concentrically around the first zone. The first and second plurality of gas exchange elements are fluidly open along a body and fluidly separated along a distal end. The first zone is configured to be fluidly coupled to an oxygen source and the second zone is configured to be fluidly coupled to a negative pressure source. A blood flow path includes a generally radial flow through the first zone to add oxygen to the blood and the second zone to separate gaseous micro emboli from the blood through the plurality of gas exchange elements.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: October 12, 2021
    Assignee: Medtronic, Inc.
    Inventors: John I. Knoll, Neil Nye, Brian Steffens, Michael Van Driel
  • Patent number: 11129771
    Abstract: An intravenous fluid bag comprising: a primary chamber configured to retain a liquid; a valve in fluid communication with the primary chamber, the valve including a housing, a spike element, and a seal, with the housing surrounding the seal, which surrounds the spike element; the spike element having a first end culminating in a tip, a second end having an inner conduit, and one or more through holes between the tip and the second end in fluid communication with the inner conduit forming part of a continuous liquid passageway in fluid communication with the primary chamber; the seal having a relaxed state preventing fluid flow through the valve, and the seal having a compressed state through which the through holes of the spike element extend allowing fluid flow from a source external the intravenous fluid bag, through the through holes, through the inner conduit, and into the primary chamber.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: September 28, 2021
    Assignee: Parasol Medical LLC
    Inventors: Patrick E. Eddy, Michael D. Kilcran
  • Patent number: 11129739
    Abstract: A bypass device may include an elongate member extending from a proximal end toward a distal end, and a proximal opening and a distal opening coupled to one another by a lumen disposed through the elongate member. The bypass device also may include at least one port extending through a side surface of the elongate tubular member, wherein at least a portion of the bypass device may be bioabsorbable.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: September 28, 2021
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: John Allen Hingston, Niklas Andersson, Moises Rivera-Bermudez, John B. Golden, Andrew Calabrese, Leah McElhaney
  • Patent number: 11129703
    Abstract: An intraluminal device and method of fixation of an intraluminal device at a recipient having an esophagus, a stomach with a cardiac portion and a GE junction between the esophagus and the cardiac portion of the stomach includes deploying the intraluminal device to the recipient. The intraluminal device has a wall defining a cardiac member that is configured to the size and shape of the cardiac portion of the stomach and deployed to the cardiac portion of the stomach and an esophageal member that is configured to the size and shape of a portion of the esophagus and deployed to the esophagus. The intraluminal device having a connector connected with the esophageal portion and cardiac portion and deployed to the GE junction. The wall is fixed to the recipient to resist distal migration of the wall. The fixing includes the wall having a wall characteristic that is configured to facilitate tissue ingrowth.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: September 28, 2021
    Assignee: BFKW, LLC
    Inventors: Randal S. Baker, Frederick J. Walburn, James A. Foote
  • Patent number: 11122795
    Abstract: The invention provides, in various embodiments, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to aortic cannulas for use in perfusion systems to return perfusate to the heart or delivering perfusate from the heart while the organ is sustained ex vivo at physiologic or near-physiologic conditions.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: September 21, 2021
    Assignee: TRANSMEDICS, INC.
    Inventors: Greg Ritchie, Vincent Lambert, II, Richard Bringham, John Sullivan, Waleed H. Hassanein
  • Patent number: 11110217
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: September 7, 2021
    Assignee: Terumo BCT, Inc.
    Inventors: Peter O'Brien, Brian M. Holmes
  • Patent number: 11103683
    Abstract: An implantable intracranial pulse pressure modulator for treating hydrocephalus in patients of all ages is disclosed as well as a system and method for use of the same. In one embodiment of the implantable intracranial pulse pressure modulator, two one-way valves are interposed in parallel, opposing orientations between a vestibule and a chamber. One of the one-way valves, in response to systole, provides fluid communication from the vestibule to the chamber such that a small aliquot of cerebrospinal fluid (CSF) is displaced from a cerebral ventricle into a ventricular catheter, thereby reducing intraventricular systolic pressure. The other one-way valve, in response to diastole, provides fluid communication from the chamber to the vestibule such that the same volume of CSF is reintroduced into a cerebral ventricle, thereby increasing intraventricular diastolic pressure. Together, both processes work synergistically to reduce intraventricular pulse pressure in order to treat hydrocephalus.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: August 31, 2021
    Inventor: Frederick H. Sklar
  • Patent number: 11103629
    Abstract: Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: August 31, 2021
    Assignee: Terumo BCT, Inc.
    Inventors: Taylor Polodna, Brian M. Holmes
  • Patent number: 11103624
    Abstract: The present disclosure relates to a hemodialysis membrane for the treatment of vascular calcification in hemodialysis patients, especially in chronic hemodialysis patients. The present disclosure further relates to methods of treating vascular calcification in hemodialysis patients, wherein the hemodialysis membrane is characterized in that it comprises at least one hydrophobic polymer and at least one hydrophilic polymer and in that it has a MWRO of between 15 and 20 kD and a MWCO of between 170-320 kD or that the hemodialysis membrane comprises at least one hydrophobic polymer and at least one hydrophilic polymer and has a MWRO of between 8.5 kD and 14.0 kD and a MWCO of between 55 kD and 130 kD.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: August 31, 2021
    Assignees: GAMBRO LUNDIA AB, CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN
    Inventors: Markus Storr, Bernd Krause, Ralf Schindler, Daniel Zickler, Bjoern Hegner