Abstract: Systems and methods for evaluating blood behavior when flowing through an implantable medical device are provided. A flow loop includes the implantable medical device, and a blood reservoir configured to contain a volume of blood and to supply blood from the volume of blood to the implantable medical device. The flow loop further includes a plurality of tubing sections coupled in flow communication between the implantable medical device and the blood reservoir, the plurality of tubing sections including a least a first tubing section having a first diameter and a second tubing section having a second diameter, wherein the second diameter is smaller than the first diameter, and a flow diverter coupled in flow communication between the plurality of tubing sections and the blood reservoir, the flow diverter comprising an outlet that is configured to be positioned below a surface of the volume of blood.

Abstract: Disclosed is a complementary-material element (22) attachable to a base plate (24) of an ostomy appliance (20) and including a first entity (30) and a second entity (32). The entities comprise different material compositions. The material composition of the second entity comprises a neutralizer which is released from the complementary-material element in response to moisture, thereby neutralizing the damaging effects of stomal output.

Abstract: A medical double configurational and multiple ports mask preferably including a multifunctional plug with or without a nebulizer oxygen delivery adaptor (“NODA”) attachment. The mask fits over the mouth and the nose and preferably contains at least two possible nose/face configurational solutions. The mask can be secured over the head with a stretchable or non-stretchable material. The position of the preferred triple ports of the double configurational mask provides improved structural construction reflecting different patient's nose/face features and allows for different types of procedures to be performed at the same time regardless of the patient's head/neck position. The multifunctional plug can be used for a variety of applications. The mask can be used with existing standardized disposable respiratory care equipment, including a simplified improved nebulizer oxygen adaptor (“SINODA”) and/or multifunctional use nebulizer oxygen delivery adaptor (“MUNODA”) attachment.

Abstract: An infusion device includes an infusion pump and an infusion tube assembly. The infusion tube assembly includes a first tube body connected to the infusion pump, a tube joint structure having first, second and third tube joints, a second tube body, and a clamping device on the second tube body. The clamping device is to clamp the second tube body. An infusion method includes instructing the infusion pump to perform an infusion operation. When bubbles are detected in a liquid in the infusion tube assembly, the infusion pump is instructed to stop the infusion operation and a bubble alarm is generated. After the infusion pump stops the infusion operation, it is determined whether a pressure of the liquid first drops to a first pressure value and then rises to a second pressure value. If yes, a rinsing operation is performed.

Abstract: A female urethral catheterization assist device and method of use. The female urethral catheterization assist device includes a pair of lateral arms pivotally connected at a middle point that enables a user to selectively open and close the lateral arms. A handle is positioned at one end of each lateral arm and a paddle is disposed at an opposing end. The paddles extend in the same direction and form an interior lateral side. Each paddle is adapted to engage with a labia minora and majora, to allow for the insertion of a female urethral catheter.

Abstract: Provided according to some embodiments of the invention are wound dressings that include a polymer matrix and nitric oxide-releasing polysiloxane macromolecules within and/or on the polymer matrix. Also provided are wound dressing kits and methods of using and forming such wound dressings.

Abstract: An apparatus and method for the batch photoactivation of mononuclear cells (MNCs) is described. The system includes a programmable controller configured to automatically separate whole blood in a first collection cycle to obtain a first quantity of MNCs; separate whole blood in a second collection cycle to obtain a second quantity of MNCs while simultaneously photoactivating the first quantity of MNCs to obtain a first quantity of treated MNCs; either store the first quantity of treated MNCs or reinfuse the first quantity of treated MNCs; photoactivate the second quantity of MNCs to obtain a second quantity of treated MNCs; either store the second quantity of treated MNCs or reinfuse the second quantity of treated MNCs; and reinfuse any blood components remaining after the second collection cycle.

Abstract: A medical wetness sensing device includes a base adapted to be disposed on a wearer of the medical wetness sensing device. The base includes a first electrical conductor and a second electrical conductor electrically insulated from the first electrical conductor. The first electrical conductor includes a hinge portion enabling a first portion of the first electrical conductor to deflect, at the hinge portion, relative to a second portion of the first electrical conductor. The medical wetness sensing device includes a controller electrically connected to the first electrical conductor and the second electrical conductor. The controller is configured to detect a presence or an absence of a medical fluid electrically connecting the first and second electrical conductors.

Abstract: A sterile solution product bag includes sterilization grade filter integrated directly into the product bag such that microbial and particulate matter filtration can be performed using the filter directly at the point of fill. The filter can include a hollow fiber filter membrane contained in a stem connected to a bladder of the product bag.

Abstract: In one representative embodiment, a method of perfusing organs in a patient's body is provided. The method comprises isolating the visceral arteries and the visceral veins from blood circulating through the patient's heart and perfusing the visceral arteries, the visceral veins, and the abdominal organs with a perfusion fluid that is fluidly separated from the blood circulating through the patient's heart. While the visceral arteries and the visceral veins are isolated, and the visceral arteries, the visceral veins, and the abdominal organs are being perfused, the patient's blood is allowed to continue to circulate through the heart.

Abstract: The present invention refers to a system and method for opening a concentrate container without the need for a human to directly handle the concentrate container and connecting the concentrate container to a blood treatment device. Aspects of the invention are directed to a container for concentrate and a blood treatment device.

Abstract: In some embodiments, a medical fluid connector is configured to receive an emitter of therapeutic agents to be emitted into a fluid pathway within the connector, the medical fluid connector comprising a proximal female end, an intermediate region, a distal male end, and a fluid pathway extending from the proximal female end, through the intermediate region, to the distal male end. A retaining structure is positioned within the intermediate region. The retaining structure is configured to securely receive an emitter of one or more therapeutic agents in a position and orientation where the fluid pathway is configured to convey fluid moving longitudinally through the fluid pathway directly into a proximal region of the emitter, around one or more lateral surfaces of the emitter, and toward the distal male end.

Abstract: Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.

Abstract: A compact catheter assembly and methods of making such a catheter are disclosed. The catheter assembly incudes a receiver and a catheter sub-assembly. The catheter sub-assembly includes a gripping member and a catheter tube carried by the gripping member.

Abstract: The present invention is directed to a dual lumen cannula configured to be inserted into a patient's body as simple as a single lumen cannula. The dual lumen cannula includes at least one inner lumen configured to be inserted into an outer lumen and connected via an inner lumen connection unit and an outer unit connection unit. Embodiments of the presenting invention further allow for the connection of at least one flow router to the other end of the inner lumen connection unit. When installed, the outer lumen is first inserted into the patient's body, followed by the insertion of the inner lumen into the outer lumen of the already cannulated patient until the inner lumen connector unit is in coupling contact with the outer lumen connector unit. Advantages of the inventive cannula presented herein include, among other things, reduction of external forces on the dual lumen cannula.

Abstract: Apparatuses and dressing components for tissue treatment with negative pressure and methods of making and using the dressings and dressing components are disclosed. For example, an apparatus for managing fluid from a tissue site may comprise at least two fluid pathways formed along the length of the apparatus. The apparatus may have at least one hinge line spanning along the length of the apparatus between at the at least two fluid pathways, and the apparatus may be curved about the hinge line. Some examples of the apparatus may comprise multiple layers assembled in a stacked relationship, which may be bonded together using weld lines to define at least two fluid pathways along the length of the apparatus. In some examples, the apparatus may be curved about the weld lines.

Abstract: The invention relates to a blood treatment device having an extracorporeal blood circuit which comprises an arterial line, a blood pump, a blood treatment unit and a venous line, wherein the arterial and venous lines can be connected to a blood vessel of a patient, and wherein the blood treatment device has an evaluation and control unit, wherein the evaluation and control unit is configured to carry out the following steps: (a1) determining the blood recirculation in a blood vessel of the patient connected to the extracorporeal blood circuit; and (b) calculating the blood flow in the blood vessel using the blood recirculation determined in accordance with (a1) and using a provided value or a value likewise previously determined for the cardiac output of the patient.

Abstract: A vial adaptor can include a connector interface and/or a piercing member. The vial adaptor can include a regulator assembly. The regulator assembly can include a regulator base, a regulator nest coupled with the regulator base, and/or a storage chamber formed at least partially by one or both of the regulator base and regulator nest. The regulator assembly can include a cover connected to one or both of the regulator base and regulator nest and fitted around a radially outward portion of one or both of the regulator base and regulator nest. In some cases, the regular assembly includes a flexible enclosure connected to the regulator nest and configured to transition between a contracted configuration and an expanded configuration. In some cases, the flexible enclosure is inhibited from transitioning to the expanded configuration prior to removal or modification of the cover from the regulator assembly.

Abstract: A glaucoma drainage device includes an elongated body extending axially from a distal end to a proximal end. The distal end forms a wedge with a leading distal edge. During implantation of the device into the suprachoroidal space of the eye, the wedge can facilitate penetration into and spreading open the tissue of the suprachoroidal space. The elongate body has one or more outer surfaces that define at least one open groove extending from at or near the proximal end towards the distal end of the body. With the distal end of the elongate body located in the suprachoroidal space of the eye and the distal end of the elongate body extending into the anterior chamber of the eye, the at least one open groove is configured such that aqueous humor flows along the open groove from the anterior chamber of the eye to the suprachoroidal space of the eye.

Abstract: An ostomy system configured to detect moisture content in a base plate or a sensor assembly part of the ostomy system, the ostomy system comprising the base plate and/or a sensor assembly part and a monitor device. The base plate or the sensor assembly part includes a first adhesive layer, a plurality of electrodes, and one or more sensing zones each covering one of one or more regions of the first adhesive layer, each of the one or more sensing zones including at least two of the plurality of electrodes. The monitor device is electrically coupled to the plurality of electrodes of the base plate or the sensor assembly part and configured to measure one or more resistances in the one or more sensing zones between the plurality of electrodes, each of the one or more resistances measured by two of the plurality of electrodes at one of the one or more sensing zones, and determine moisture content of the first adhesive layer at each of the one or more sensing zones based on the measured one or more resistances.