Abstract: Methods of making mixed allergen compositions, e.g., substantially aerobic organism free mixed allergen compositions, and the resulting allergen composition, are provided.
Type:
Grant
Filed:
June 3, 2022
Date of Patent:
September 17, 2024
Assignee:
Societe des Produits Nestle S.A.
Inventors:
Ashley Dombkowski, Christopher Cornyn, Albert E. Rosevear, Olivia M. Weihe, Cosmin M. Beliciu, Alexandra F. Russell, Antoinette de Senna
Abstract: Methods and compositions for increasing LDL receptor levels in a plurality of cells are disclosed. For example, the methods include providing to the cells a curcumin composition that is at least 15% curcumin II or at least 5% curcumin III, in order to increase LDL receptor levels. In addition, compositions for increasing LDL receptor levels in a plurality of cells are disclosed, which include a curcumin composition consisting of at least 15% curcumin II or at least 5% curcumin III (or combinations of such curcuminoids), along with a pharmaceutically-acceptable solvent, filler, or carrier. Still further, methods and compositions for decreasing MSK1 levels in a plurality of cells are disclosed, which involve administering a curcumin III-enriched composition to the cells.
Abstract: The composition for treating bone loss is an alcoholic extract of Lavandula atriplicifolia plant flowers and leaves. The composition is prepared by extracting dried Lavandula plant flower and leaf powder in ethanol or methanol for at least 4 hours in a Soxhlet apparatus. The Lavandula atriplicifolia extract acts by both stimulating osteogenesis and inhibiting adipogenesis. The composition may be used to form drug compositions for treating bone loss.
Type:
Grant
Filed:
May 13, 2024
Date of Patent:
September 10, 2024
Assignee:
KING FAISAL UNIVERSITY
Inventors:
Basem Mohamed Abdallah, Enas Mohamed Ali
Abstract: This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a mammal undergoing such chemotherapy.
Abstract: The method for producing a plant cell extract of hydroxyl rich glycoproteins (HRGP), including extensins, by extraction from plant cell walls (PCW), comprises subjecting a biomass of whole dedifferentiated plant cells to the following treatment: —Breaking the cells for producing a cell homogenate in which the intracellular molecules are solubilized; —Eliminating the solubilized intracellular molecules by washing the cell homogenate with water and diafiltering on a 0.2 ?m filter; —Extracting the HRGP from the PCW by adding a salt thereby forming an HRGP enriched salted extract suspension; —Filtering the HRGP enriched salted extract suspension to discard the PCW debris and recover the desired enriched HRGP salted extract.
Abstract: Disclosed herein are compositions for treating, ameliorating, preventing, or reducing the symptoms associated with menopause and/or hot flashes. The compositions disclosed herein comprise a curcumin composition, a green tea extract composition, and a phycocyanin composition that act as neurokinin 3 receptor antagonists. Also described herein are methods utilizing the aforementioned compositions.
Abstract: The disclosure provides a composition for inhibiting thrombosis. The composition includes 5 to 25% by weight of Fish Oil, 15 to 55% by weight of Willow Bark Extract, and 0.2 to 5% by weight of Vitamin E.
Type:
Grant
Filed:
May 3, 2022
Date of Patent:
August 20, 2024
Assignee:
P TECH, LLC
Inventors:
Peter M. Bonutti, Justin E. Beyers, Tonya M. Bierman
Abstract: The present invention relates to the use of a milk whey protein hydrolysate for preventing or treating transepidermal water loss (TEWL) and/or TEWL-associated disorders or/and enhancing skin barrier function in young and adult mammals. The protein hydrolysate may be used in the prevention or treatment of TEWL-associated disorders, such as atopic dermatitis, dry or reactive skin or skin dehydration. It may also be used in the cosmetic use of improving skin appearance.
Abstract: A method for topically treating skin is disclosed. The method can include applying to skin a composition that includes tetrahexyldecyl ascorbate, Morus alba fruit extract, Acmella oleracea extract, and retinol, wherein topical application of the composition treats the skin.
Type:
Grant
Filed:
May 16, 2023
Date of Patent:
August 13, 2024
Assignee:
MARY KAY INC.
Inventors:
Geetha Kalahasti, Patricia Jacoby, Milagros Sanchez, Shona Burkes-Henderson, David Gan
Abstract: One aspect of the present application relates to a storage stable pharmaceutical composition comprising a sulfated glycosaminoglycan having an average molecular weight ranging from 3,000 to 15,000 Daltons, and a pharmaceutical carrier, where the pharmaceutical carrier is mixed with the sulfated glycosaminoglycan, as well as this composition's use in a method of treating a subject for a medically observable improvement. Another aspect of the present application relates to a process for producing a storage stable purified sulfated glycosaminoglycan.
Type:
Grant
Filed:
September 28, 2023
Date of Patent:
August 13, 2024
Assignee:
ADORA ANIMAL HEALTH CORPORATION
Inventors:
Thomas Michael Vaughn, David J. Fairfax, John Quinn, Karl F. Popp, Thomas Edward D'Ambra
Abstract: A composition for treating osteoporosis comprising Acroceras macrum gold nanoparticles (AM-AuNPs). The composition is prepared by mixing an Acroceras macrum extract with an aqueous chloroauric acid (HAuCl4) solution to provide a mixture including the Acroceras macrum gold nanoparticles; removing unreacted Acroceras macrum extract from the mixture followed by purifying the Acroceras macrum gold nanoparticles; and obtaining the gold nanoparticle composition comprising the Acroceras macrum gold nanoparticles (AM-AuNPs). The composition may be used to form drug compositions for treating osteoporosis.
Type:
Grant
Filed:
January 31, 2024
Date of Patent:
August 6, 2024
Assignee:
KING FAISAL UNIVERSITY
Inventors:
Basem Mohamed Abdallah, Enas Mohamed Ali
Abstract: Disclosed herein are compositions for supporting bladder health and/or treating, ameliorating, preventing, or reducing overactive bladder or the symptoms associated therewith. The compositions disclosed herein comprise a beta-adrenergic receptor agonist and at least one muscarinic receptor antagonist. Also described herein are methods utilizing the aforementioned compositions.
Type:
Grant
Filed:
October 18, 2023
Date of Patent:
July 30, 2024
Assignee:
Bonafide Health, LLC
Inventors:
James R. Komorowski, Sarah Sylla, Devon Bernsley
Abstract: Compositions and methods for bone health, cartilage health or both, are disclosed that include preparing and utilizing a mixture of at least one Morus extract enriched for one or more prenylated flavonoids, at least one Scutellaria extract enriched for one or more free-B-ring flavonoids, and at least one Acacia extract enriched for one or more flavans.
Abstract: A herbal composition for relieving sleep disorder, comprising, by percentage weight, active ingredients of 2.5% Hovenia extract, 12.5% rattan extract, 7.5% lemon extract, 7.5% jujube kernels extract, 15% valerian root extract, and 5% panax notoginseng; auxiliary ingredients of 0.05% vitamin B1, 0.50% vitamin B3, 0.05% vitamin B6, 0.01% folic acid (vitamin B9), and 0.10% vitamin B12; and an accessory composition of 36.97% xylitol, 7.39% cellulose, 1.97% stearic acid, 0.99% natural color and flavor, 0.99% silicon dioxide, 0.49% croscarmellose Na, and 0.49% magnesium stearate. The herbal composition has significant anxiolytic effect, well-maintained bioavailability of DHM, no significant toxic or side effect and not causing addictive or withdrawal effect, thereby prolonging sleep duration and quality without causing any significant side effect.
Abstract: Provided are compositions that stimulate the oxytocin receptor in the skin of a subject thereby leading to improved skin appearance and youthfulness. Also provided are processes of rejuvenating the skin of a subject to improve a youthful appearance by application of one or more compositions as provided herein.
Abstract: A method for treatment of cancer, the method comprises preparing a solid water particle solution and a Chinese herb composition; administering a predetermined amount of the solid water particle solution three times a day and a predetermined amount of the Chinese herb composition two times a day, and continue the administering for 14 days to complete a course of treatment; and determining healing effects of the cancer by taking blood test, wherein the Chinese herb composition consists of Scutellaria barbata, Lobelia chinensis, Paris polyphylla, Prunella vulgaris, Artemisia capillaris, Chinese Thorawax Root, White Peony Root, Houpoea officinalis, Indian Bread peel, Asiatic Plantain Seed, Astragalus membranaceus, Angelica sinensis, Dried Tangerine Peel, Common Burreed Rhizome, Blue Turmeric Rhizome, and Japanese Honeysuckle Stem.
Abstract: According to an aspect of the present application, a composition for controlling a target pest comprises 0.1% to 4% isopropyl myristate, 0.1% to 15% thyme oil white, 0.1% to 2% geraniol, and at least one additional active ingredient selected from thymyl acetate, linalyl acetate, amyl butyrate, anise star oil, black seed oil, p-cymene, linalool, d-limonene, isopropyl myristate, lilac flower oil, methyl salicylate, alpha-pinene, piperonal, piperonyl alcohol, tetrahydrolinalool, thyme oil white, thyme oil red, thymol, vanillin, and wintergreen oil. The composition causes synergistic control of the target pest.
Abstract: Provided are a pharmaceutical composition or a pharmaceutical composition raw material, which contains supernatant from a culture medium used during culture to induce pluripotent stem cells.
Abstract: The invention provides therapeutic compositions containing willow extract, such as willow leaf extract, methods of medical treatment using such compositions, and methods for preparing such compositions.
Type:
Grant
Filed:
March 29, 2022
Date of Patent:
July 9, 2024
Assignees:
Shireen Nature Company for General Trading Ltd.
Abstract: Provided is a composition for alleviating fatigue or enhancing exercise capability including extracts or fractions of Angelica gigas, Cnidium officinale, and Paeonia lactiflora as active ingredients. The composition including the extracts or fractions of Angelica gigas, Cnidium officinale, and Paeonia lactiflora as active ingredients may effectively alleviate fatigue accumulated in the body and enhance exercise capability by multilaterally controlling various factors involved in physical fatigue and/or enhancement of exercise capability. Specifically, the composition may effectively control the factors related to fatigue by increasing the expression level of HO-1 by activating the Nrf-2 pathway. Also, since extracts of natural plants or fractions thereof are used as active ingredients, the composition is completely harmless to the human body and may be used safely.
Type:
Grant
Filed:
September 24, 2019
Date of Patent:
July 9, 2024
Assignee:
KOLMAR BNH CO., LTD
Inventors:
Hyun Kyu Kim, Hak Sung Lee, Seul Ki Kim, Da Ae Kwon, Young Sang Kim