Patents Examined by Qiuwen Mi
  • Patent number: 12076434
    Abstract: The method for producing a plant cell extract of hydroxyl rich glycoproteins (HRGP), including extensins, by extraction from plant cell walls (PCW), comprises subjecting a biomass of whole dedifferentiated plant cells to the following treatment: —Breaking the cells for producing a cell homogenate in which the intracellular molecules are solubilized; —Eliminating the solubilized intracellular molecules by washing the cell homogenate with water and diafiltering on a 0.2 ?m filter; —Extracting the HRGP from the PCW by adding a salt thereby forming an HRGP enriched salted extract suspension; —Filtering the HRGP enriched salted extract suspension to discard the PCW debris and recover the desired enriched HRGP salted extract.
    Type: Grant
    Filed: July 4, 2019
    Date of Patent: September 3, 2024
    Assignee: Croda Italiana S.P.A.
    Inventors: Chiara Marzotto, Roberto Dal Toso
  • Patent number: 12070482
    Abstract: Disclosed herein are compositions for treating, ameliorating, preventing, or reducing the symptoms associated with menopause and/or hot flashes. The compositions disclosed herein comprise a curcumin composition, a green tea extract composition, and a phycocyanin composition that act as neurokinin 3 receptor antagonists. Also described herein are methods utilizing the aforementioned compositions.
    Type: Grant
    Filed: September 1, 2023
    Date of Patent: August 27, 2024
    Assignee: Bonafide Health, LLC
    Inventors: James R. Komorowski, Sarah Sylla
  • Patent number: 12064456
    Abstract: The disclosure provides a composition for inhibiting thrombosis. The composition includes 5 to 25% by weight of Fish Oil, 15 to 55% by weight of Willow Bark Extract, and 0.2 to 5% by weight of Vitamin E.
    Type: Grant
    Filed: May 3, 2022
    Date of Patent: August 20, 2024
    Assignee: P TECH, LLC
    Inventors: Peter M. Bonutti, Justin E. Beyers, Tonya M. Bierman
  • Patent number: 12064506
    Abstract: The present invention relates to the use of a milk whey protein hydrolysate for preventing or treating transepidermal water loss (TEWL) and/or TEWL-associated disorders or/and enhancing skin barrier function in young and adult mammals. The protein hydrolysate may be used in the prevention or treatment of TEWL-associated disorders, such as atopic dermatitis, dry or reactive skin or skin dehydration. It may also be used in the cosmetic use of improving skin appearance.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: August 20, 2024
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Carine Blanchard, Sebastien Holvoet
  • Patent number: 12059430
    Abstract: One aspect of the present application relates to a storage stable pharmaceutical composition comprising a sulfated glycosaminoglycan having an average molecular weight ranging from 3,000 to 15,000 Daltons, and a pharmaceutical carrier, where the pharmaceutical carrier is mixed with the sulfated glycosaminoglycan, as well as this composition's use in a method of treating a subject for a medically observable improvement. Another aspect of the present application relates to a process for producing a storage stable purified sulfated glycosaminoglycan.
    Type: Grant
    Filed: September 28, 2023
    Date of Patent: August 13, 2024
    Assignee: ADORA ANIMAL HEALTH CORPORATION
    Inventors: Thomas Michael Vaughn, David J. Fairfax, John Quinn, Karl F. Popp, Thomas Edward D'Ambra
  • Patent number: 12059491
    Abstract: A method for topically treating skin is disclosed. The method can include applying to skin a composition that includes tetrahexyldecyl ascorbate, Morus alba fruit extract, Acmella oleracea extract, and retinol, wherein topical application of the composition treats the skin.
    Type: Grant
    Filed: May 16, 2023
    Date of Patent: August 13, 2024
    Assignee: MARY KAY INC.
    Inventors: Geetha Kalahasti, Patricia Jacoby, Milagros Sanchez, Shona Burkes-Henderson, David Gan
  • Patent number: 12053499
    Abstract: A composition for treating osteoporosis comprising Acroceras macrum gold nanoparticles (AM-AuNPs). The composition is prepared by mixing an Acroceras macrum extract with an aqueous chloroauric acid (HAuCl4) solution to provide a mixture including the Acroceras macrum gold nanoparticles; removing unreacted Acroceras macrum extract from the mixture followed by purifying the Acroceras macrum gold nanoparticles; and obtaining the gold nanoparticle composition comprising the Acroceras macrum gold nanoparticles (AM-AuNPs). The composition may be used to form drug compositions for treating osteoporosis.
    Type: Grant
    Filed: January 31, 2024
    Date of Patent: August 6, 2024
    Assignee: KING FAISAL UNIVERSITY
    Inventors: Basem Mohamed Abdallah, Enas Mohamed Ali
  • Patent number: 12048712
    Abstract: Disclosed herein are compositions for supporting bladder health and/or treating, ameliorating, preventing, or reducing overactive bladder or the symptoms associated therewith. The compositions disclosed herein comprise a beta-adrenergic receptor agonist and at least one muscarinic receptor antagonist. Also described herein are methods utilizing the aforementioned compositions.
    Type: Grant
    Filed: October 18, 2023
    Date of Patent: July 30, 2024
    Assignee: Bonafide Health, LLC
    Inventors: James R. Komorowski, Sarah Sylla, Devon Bernsley
  • Patent number: 12042523
    Abstract: Compositions and methods for bone health, cartilage health or both, are disclosed that include preparing and utilizing a mixture of at least one Morus extract enriched for one or more prenylated flavonoids, at least one Scutellaria extract enriched for one or more free-B-ring flavonoids, and at least one Acacia extract enriched for one or more flavans.
    Type: Grant
    Filed: December 19, 2022
    Date of Patent: July 23, 2024
    Assignee: Unigen, Inc.
    Inventors: Qi Jia, Ping Jiao, Mesfin Yimam, Teresa Horm
  • Patent number: 12036259
    Abstract: A method for treatment of cancer, the method comprises preparing a solid water particle solution and a Chinese herb composition; administering a predetermined amount of the solid water particle solution three times a day and a predetermined amount of the Chinese herb composition two times a day, and continue the administering for 14 days to complete a course of treatment; and determining healing effects of the cancer by taking blood test, wherein the Chinese herb composition consists of Scutellaria barbata, Lobelia chinensis, Paris polyphylla, Prunella vulgaris, Artemisia capillaris, Chinese Thorawax Root, White Peony Root, Houpoea officinalis, Indian Bread peel, Asiatic Plantain Seed, Astragalus membranaceus, Angelica sinensis, Dried Tangerine Peel, Common Burreed Rhizome, Blue Turmeric Rhizome, and Japanese Honeysuckle Stem.
    Type: Grant
    Filed: November 8, 2023
    Date of Patent: July 16, 2024
    Inventor: Shui Yin Lo
  • Patent number: 12036260
    Abstract: A herbal composition for relieving sleep disorder, comprising, by percentage weight, active ingredients of 2.5% Hovenia extract, 12.5% rattan extract, 7.5% lemon extract, 7.5% jujube kernels extract, 15% valerian root extract, and 5% panax notoginseng; auxiliary ingredients of 0.05% vitamin B1, 0.50% vitamin B3, 0.05% vitamin B6, 0.01% folic acid (vitamin B9), and 0.10% vitamin B12; and an accessory composition of 36.97% xylitol, 7.39% cellulose, 1.97% stearic acid, 0.99% natural color and flavor, 0.99% silicon dioxide, 0.49% croscarmellose Na, and 0.49% magnesium stearate. The herbal composition has significant anxiolytic effect, well-maintained bioavailability of DHM, no significant toxic or side effect and not causing addictive or withdrawal effect, thereby prolonging sleep duration and quality without causing any significant side effect.
    Type: Grant
    Filed: September 11, 2023
    Date of Patent: July 16, 2024
    Inventor: Jing Liang
  • Patent number: 12036245
    Abstract: Provided are a pharmaceutical composition or a pharmaceutical composition raw material, which contains supernatant from a culture medium used during culture to induce pluripotent stem cells.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: July 16, 2024
    Assignee: I Peace, Inc.
    Inventors: Koji Tanabe, Kenta Suto
  • Patent number: 12035713
    Abstract: According to an aspect of the present application, a composition for controlling a target pest comprises 0.1% to 4% isopropyl myristate, 0.1% to 15% thyme oil white, 0.1% to 2% geraniol, and at least one additional active ingredient selected from thymyl acetate, linalyl acetate, amyl butyrate, anise star oil, black seed oil, p-cymene, linalool, d-limonene, isopropyl myristate, lilac flower oil, methyl salicylate, alpha-pinene, piperonal, piperonyl alcohol, tetrahydrolinalool, thyme oil white, thyme oil red, thymol, vanillin, and wintergreen oil. The composition causes synergistic control of the target pest.
    Type: Grant
    Filed: November 17, 2023
    Date of Patent: July 16, 2024
    Assignee: TYRATECH, INC.
    Inventor: Essam Enan
  • Patent number: 12036310
    Abstract: Provided are compositions that stimulate the oxytocin receptor in the skin of a subject thereby leading to improved skin appearance and youthfulness. Also provided are processes of rejuvenating the skin of a subject to improve a youthful appearance by application of one or more compositions as provided herein.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: July 16, 2024
    Assignee: Endoderm Laboratories, LLC
    Inventors: Nicole Hayre, John E. Kulesza
  • Patent number: 12029770
    Abstract: Provided is a composition for alleviating fatigue or enhancing exercise capability including extracts or fractions of Angelica gigas, Cnidium officinale, and Paeonia lactiflora as active ingredients. The composition including the extracts or fractions of Angelica gigas, Cnidium officinale, and Paeonia lactiflora as active ingredients may effectively alleviate fatigue accumulated in the body and enhance exercise capability by multilaterally controlling various factors involved in physical fatigue and/or enhancement of exercise capability. Specifically, the composition may effectively control the factors related to fatigue by increasing the expression level of HO-1 by activating the Nrf-2 pathway. Also, since extracts of natural plants or fractions thereof are used as active ingredients, the composition is completely harmless to the human body and may be used safely.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: July 9, 2024
    Assignee: KOLMAR BNH CO., LTD
    Inventors: Hyun Kyu Kim, Hak Sung Lee, Seul Ki Kim, Da Ae Kwon, Young Sang Kim
  • Patent number: 12029772
    Abstract: The invention provides therapeutic compositions containing willow extract, such as willow leaf extract, methods of medical treatment using such compositions, and methods for preparing such compositions.
    Type: Grant
    Filed: March 29, 2022
    Date of Patent: July 9, 2024
    Assignees: Shireen Nature Company for General Trading Ltd.
    Inventor: Mustafa Barzani
  • Patent number: 12023359
    Abstract: The present invention relates to compositions comprising phospholipids for delivery of bioactive compounds such as ethyl esters, fish oil concentrates, cannabinoids, CoQ10 and curcumin under conditions such the bioavailability of the bioactive compounds is enhanced.
    Type: Grant
    Filed: October 18, 2023
    Date of Patent: July 2, 2024
    Assignee: AKER BIOMARINE HUMAN INGREDIENTS AS
    Inventors: Thomas Repstad, Finn Myhren, Nils Hoem
  • Patent number: 12016957
    Abstract: The present description relates to a method for extracting at least one substance of interest, the method comprising the following steps: —providing an admixture comprising water, a source comprising the at least one substance of interest or at least one precursor thereof, at least one surfactant and at least one lipophilic compound; —the emulsification of the admixture, leading to the formation of an emulsion; wherein the emulsion comprises: —a continuous aqueous phase; and a discontinuous lipidic phase comprising the at least one lipophilic compound, the at least one surfactant and at least one substance of interest extracted from the source during the emulsification; wherein the method further comprises the addition of at least one cryoprotectant to the admixture and the lyophilization of the emulsion.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: June 25, 2024
    Assignees: AVIGNON UNIVERSITE, LYOFAL, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER, UNIVERSITE DE MONTPELLIER
    Inventors: Christiane Contino-Pepin, Stéphane Desgranges, Alice Dall'armellina, Charles Duval, Mathias Letan-Martin
  • Patent number: 12011496
    Abstract: The present invention provides a topical formulation and method of use where the formulation comprises macqui berry or a macqui berry extract containing anthocyanins having a very high oxygen radical absorbance capacity (ORAC). The formulation provides the macqui berry in a stabilized form which includes a glucuronide or glycuronide, a photostabilizing agent, encapsulation, or light- and/or air-blocking packaging.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: June 18, 2024
    Assignee: Tracie Martyn International, Inc.
    Inventor: Marius Morariu
  • Patent number: 12011451
    Abstract: Compositions and methods of use of treatment of one or more of ovarian cancer, endometrial cancer, head and neck cancer, noncancerous gynecological disorders, and estrogen sensitive cancers, the composition comprising an effective amount of a cannabinoid and a flavonoid wherein the method comprises administering to a patient in need thereof an effective amount of the composition and optionally administering the composition concomitantly with a chemotherapeutic agent.
    Type: Grant
    Filed: October 25, 2023
    Date of Patent: June 18, 2024
    Assignees: Ecofibre USA Inc., The University of Newcastle
    Inventors: Alexandra M. Capano, Pradeep Singh Tanwar