Abstract: An intravascular catheter for peri-vascular or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. A method can involve injection/infusion of the ablative fluid over an extended time period of at least 10 seconds or with two injections at two different penetration depths to reduce or eliminate patient pain during ablation.

Abstract: An apparatus includes a catheter, a housing configured to house at least a portion of the catheter, and an actuator movably coupled to the housing. The housing has a first port configured to receive a proximal end portion of the catheter and a second port configured to couple the housing to an indwelling vascular access device. A portion of the actuator is disposed within the housing and is configured to be movably coupled to a portion of the catheter. The actuator is configured to be moved a first distance to move a distal end portion of the catheter a second distance greater than the first distance from a first position to a second position. The distal end portion of the catheter is disposed within the housing when in the first position and is distal to the indwelling vascular access device when in the second position.

Abstract: A catheter system may include a catheter lumen, first and second electrodes, and a sensor in communication with the first and second electrodes. The sensor may be configured to detect at least one of: a bulk volume of blood within a blood vessel and extravasation of a drug from the blood vessel into soft tissue adjacent the blood vessel. Other catheter systems may include a catheter lumen and a sensing chip coupled to the catheter lumen. The sensing chip may be configured to detect at least one of: a bulk volume of blood within a blood vessel and extravasation of a drug from the blood vessel into soft tissue adjacent the blood vessel.

Abstract: A nose respirator device with a holder connected to a base. The holder has a top which is configured to sit on a nasal bridge and is joined on each side with an arm which extends downward and each arm joins the base which is configured to sit across a subnasale underneath nose tip. The base contains two separate open cavities, each open cavity has an upper opening shaped like a cone suitable for insertion into a nostril. Each open cavity of the two separate open cavities can be further divided by a separator into two channels. Valves installed along inside wall of each channel control air flow as the valves are configured to open only in one direction when being pushed by air current. Filters can be fitted into each cavity or each channel within each cavity for air cleaning.

Abstract: An automatic drug delivery device, for dispensing a fluid medicament, includes: a longitudinal housing; a removable cap; a syringe assembly having a hollow syringe body and an injection needle; and a drive mechanism. The loaded drive mechanism is operatively coupled with a safety shield movable within the longitudinal housing. The safety shield is biased into a proximal position in which it protrudes out of the proximal end of the longitudinal housing in order to cover a needle tip of the injection needle. The safety shield is movable into a distal position in which the injection needle is exposed for injection. The device includes a feedback mechanism providing a visual feedback to the user indicating an actual state of operation. The feedback mechanism includes a visual indicator which appears in a transparent window on the distal end of the housing.

Abstract: The present disclosure, in its various aspects, is directed generally to medical devices, and more specifically to catheter accessory devices and related systems and methods. In an embodiment, an instrument accessory device may include a body with an instrument lumen through which an instrument may extend through. An expandable member may be disposed about the distal end of the body. An elongate delivery member may be attached to the body and in communication with the expandable member at a distal end of the delivery member. The delivery member may be configured to slide the instrument lumen of the body and the expandable member along the length of the instrument when extended therethrough. Other embodiments are addressed within.

Abstract: Disclosed is a drug eluting balloon for a balloon catheter. The drug eluting balloon comprises a balloon body (100) and a coating (200), and the coating (200) comprises a water-soluble adhesive layer (210), an isolating layer (220) and a drug layer (230) from the inside out. After the drug eluting balloon is pushed to a diseased part, the balloon body (100) is expanded, and the water-soluble adhesive layer (210) dissolves due to scouring by a blood flow, such that the isolating layer (220) and the drug layer (230) are separated from an outer surface of the balloon body (100) and adhere to a blood vessel wall.

Abstract: Described is an electronics assembly with pressure or force sensing capabilities for use in a drug delivery device. The electronics assembly includes a processor, a sensor arranged to measure the force applied by a drive mechanism to drive a medicament from a cartridge, a wireless module to which an external device can be paired, a power module arranged to supply power to the assembly, and memory storing instructions for the processor to perform. The instructions include receiving a measurement signal during the drug delivery operation, and determining if the dose of the medicament was expelled from the drug delivery device based on the received measurement signal.

Abstract: A flue for use with an ultrasonic surgical tip, comprising protrusions or bumps on its inner surface with improved protrusion pattern, density and location. The flue has enhanced cooling effect for the ultrasonic surgical tip.

Abstract: A medical probe, including a flexible insertion tube having a proximal segment and a deflectable distal segment, and containing first and second proximal tubular structures, first and second distal lumens, and first and second wires. The first and second proximal tubular structures are twisted around each other in the proximal segment. The first and lumens are parallel to each other in the deflectable distal segment. The first and second wires run respectively through the first and second proximal tubular structures and the first and second distal lumens. The first and second wires have respective first and second proximal ends which deflect the deflectable distal segment when the respective proximal ends are pulled.

Abstract: Improved apparatus for use with medication in fluid form, which is particularly beneficial for medications having a relatively high viscosity. The disclosed syringe adapter has an opening that is relatively large, as compared to a conventional needle, and thus affixing the disclosed syringe adapter to a syringe improves syringeability of higher-viscosity medications. Some embodiments feature a lateral extension that prevents inserting the syringe adapter too far into a medicine bottle, and some embodiments feature a component that assists in firmly grasping. When the disclosed syringe adapter is affixed to a pistol-grip or tab-handled syringe, the medication withdrawn into the pistol-grip syringe can be more easily administered from the syringe barrel. In some embodiments, the syringe adapter will be replaced with a needle prior to injecting the medication, while in some other embodiments, the needle is affixed to the in-place syringe adapter for the injection.

Abstract: Provided are a method, apparatus, and computer program for providing a notification according to a period of use of a drug infusion device. A time point at which the drug infusion device switches from an inactive mode to an active mode may be determined as a use start time point. Also, an impending expiration notification indicating that expiration of a period of use of the drug infusion device is imminent may be provided at a first time point after a certain period from the use start time point, based on a usable period and a user set time of the drug infusion device. In addition, an expiration notification indicating that the period of use of the drug infusion device has expired may be provided at a second time point after the usable period from the use start time point.

Abstract: An apparatus is provided which includes a plurality of conduits and a plurality of valves in fluidic communication with the plurality of conduits. The plurality of conduits is configured to receive liquid from at least one liquid reservoir configured to be implanted on or within a recipient. Each conduit of the plurality of conduits has a corresponding flow resistance to the liquid. The plurality of valves is configured to controllably allow flow of the liquid through a selected set of the conduits to be administered internally to the recipient with a selected flow rate.

Abstract: An electric flusher configured to clean a private part of a human body is provided. The electric flusher includes a base, a flushing head, and a driving assembly. The base defines a mounting space therein. The flushing head is disposed on a top portion of the base. The driving assembly is mounted in the mounting space. The driving assembly is connected to the flushing head, so that the flushing head swings or rotates in a first direction. Alternatively, the electric flusher includes the base for holding, the flushing head disposed on the top portion of the base, and an FPC germicidal lamp mounted on an outer wall of the flushing head. The electric flusher is able to comprehensively clean the private part of the human body and effectively remove dirt and bacteria.

Abstract: Provided is a container for connection to a device for suctioning bodily fluids and for supplying a fluid substance to a human or animal body, said container comprising an interior which is divided into a first region for collecting the suctioned bodily fluids and into a second region for providing the fluid substance, The first region of the interior is separated from the second region by means of a flexibly realized partition wall.

Abstract: In some embodiments an apparatus for providing access for a medical procedure in a patient's body cavity includes a stem configured for insertion through an opening in a body cavity wall. The stem has a bore and a cap is disposed at a proximal end thereof and includes an entry port in communication with the bore which receives an instrument to be inserted into the body cavity. An inflatable annular seal is disposed on the stem proximate the cap and a conduit extends through the cap providing pressurized gas at a first outlet in fluid communication with the body cavity providing insufflation pressure. A second outlet of the conduit is in fluid communication the seal, which when disposed inside the body cavity proximate the wall and inflated by pressurized gas, bears on an inner surface of the wall urging the cap into contact with an outer surface of the wall while sealing the opening.

Abstract: A pump comprises a drive mechanism, a tube coupled to the drive mechanism, a filament coupled to the tube and extendable into the tube by the drive mechanism and at least one check valve coupled to the tube. As the filament is forced by the drive mechanism into the tube, fluid contained in the tube is forced by the filament through the at least one check valve and out of the tube.

Abstract: A guide catheter extension, having a push member having a proximal end and a distal end; a tube frame coupled to the distal end of the push member, the tube frame defining a lumen having a diameter sufficient to receive an interventional vascular device therethrough; and an inflatable element coupled to the tube frame, wherein the inflatable element is expandable into the lumen.

Abstract: The present disclosure pertains to medical device such as a dialysis device for performing a hemodialysis, and/or hemofiltration and/or hemodiafiltration. The medical device can include a first functional module and a second functional module, wherein an operating hours counter for counting the operating hours is provided in the first functional module, and wherein the first functional module is configured to store an operating hours value determined by the operating hours counter in a first storage of the first functional module. In some embodiments, a second storage is provided in the second functional module, wherein the second functional module is configured to store the operating hours value determined by the operating hours counter of the first functional module in the second storage.

Abstract: A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method also includes introducing a first substance into a distal end of the body interior. The method further includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. Moreover, the method includes introducing a second substance into the body interior. In addition, the method includes disposing a proximal stopper member in the body interior. The method also includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method further includes coupling a plunger member to the proximal stopper member.