Patents Examined by Rachel T. Smith
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Patent number: 12042629Abstract: A bio-electroceutical device includes: a cell reservoir configured to accommodate a cell cluster comprising an organoid fused with a biomaterial; and a cell controller configured to control, using an electrical signal, a secretion of an active component by the organoid in the cell cluster.Type: GrantFiled: November 9, 2020Date of Patent: July 23, 2024Assignee: Samsung Electronics Co., Ltd.Inventors: Young Jun Hong, Hyejin Park, Seokyung Kang, Soyoung Bang, Sang Joon Kim, Chisung Bae
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Patent number: 12036377Abstract: A hand-operated flow regulator is adapted to be inserted between an elastomeric bulb pump and a tubing as a part of an enema flow path. The hand-operated flow regulator comprises a main flow body, and a tubular pump coupling end part having a free pump coupling end and defining a first flow section. The tubular pump coupling end part extends via an exterior regulator body part into a tubular tube coupling end part having a free tube coupling end and defining a second flow section. An interior regulator body part is situated rotatable and substantially coaxially inside the exterior regulator body part, and a pivotable grip is in operative communication with the interior regulator body part to open and close the enema flow path.Type: GrantFiled: December 7, 2021Date of Patent: July 16, 2024Assignee: Qufora A/SInventors: Henrik Bork Bjerregaard, Ole Hougaard, Lars Monroy, Kristian Bjerg
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Patent number: 12036033Abstract: The present invention is related to a vaginal drug delivery device and to a vaginal diagnostic device that comprises a first and second rigid member, wherein the first and/or second rigid member comprises a reservoir holding a medicament to be delivered, an opening, and a pump for pumping said medicament out of said opening, and/or wherein the first rigid member and/or second rigid member comprises a diagnostic device for performing an intravaginal diagnosis or measurement therefor. The device further comprises a first flexible member and flexible part, wherein at least one of the first flexible member and the flexible part is at least partially elastic having an elasticity such that the device can be squeezed from an extended shape to a collapsed shape. The device is pre-biased to assume the extended shape when little to no external force is being applied thereto.Type: GrantFiled: January 22, 2021Date of Patent: July 16, 2024Assignee: LiGalli B.V.Inventor: Wilhelmus Nicolaas Gerardus Maria De Laat
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Patent number: 12029883Abstract: A syringe assembly includes a syringe and a vibrator configured to vibrate at at least one frequency to reduce stopper friction. The vibrator is attached to the syringe. The syringe assembly may further include an infusion pump configured to draw fluid from the syringe with a negative pressure.Type: GrantFiled: March 19, 2019Date of Patent: July 9, 2024Assignee: Becton, Dickinson and CompanyInventor: Austin Jason McKinnon
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Patent number: 12029448Abstract: A pad is provided having a body for providing a gas seal over a surgical site, a port extending between a first surface of the body and a second surface of the body and sized accept a surgical instrument, and a lumen situated along the body and having a first opening and a second opening, the second opening aligned with the surgical site for communicating a fluid flow to the surgical site.Type: GrantFiled: October 12, 2023Date of Patent: July 9, 2024Assignee: Saphena Medical, Inc.Inventors: Mark J. Orphanos, Michael Glennon, Michael Barenboym
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Patent number: 12016989Abstract: According to the present invention, blood access formed by a percutaneous terminal for hemodialysis is performed, the percutaneous terminal provided with: a contact body comprising a biocompatible member that comes into contact with skin tissue inside and outside a living body; a tubular body having one end connected to an artery and the other end connected to a vein; a blood removal tubular body having one end connected to a side surface of the tubular body and supplying blood to an external blood circuit; and a retransfusing tubular body having one end connected to the vein and the other end connected to a retransfusing portion of the blood circuit, wherein the other end of the blood removal tubular body and the retransfusing tubular body are located at a central portion of the contact body. Furthermore, provided is a hemodialysis system that is less burdensome for a patient and enables stable blood access.Type: GrantFiled: July 1, 2019Date of Patent: June 25, 2024Assignee: KABUSHIKI KAISYA ADVANCEInventor: Nobuchika Urakabe
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Patent number: 12017022Abstract: Devices, systems for localized delivery of a chemotherapy, hormonal therapy or targeted drug/biologic therapy to a target tissue area of an internal body organ of a patient. A catheter 10 forms a sealed treatment chamber in a natural lumen extending through the target tissue area. Air is purged from the chamber, which is then filled with a liquid drug solution for an adequate treatment session time, solution volume and drug concentration to saturate the target tissue area, thereby providing the treatment. The liquid drug solution may be circulated or recirculated through the chamber or maintained stationary therewithin. The drug may saturate the target tissue area and pass therethrough into the lymphatic system or interstitial space, which may serve as a reservoir of the drug for continued therapeutic treatment after withdrawal of the catheter. The chamber is evacuated at the end of the treatment session.Type: GrantFiled: November 16, 2018Date of Patent: June 25, 2024Assignee: ISOLA THERAPEUTICS, INC.Inventor: Brian H. Craig
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Patent number: 12011553Abstract: A patient access site securement system includes a housing with an inlet, an outlet and an internal fluid path between the inlet and the outlet. The housing also has a connecting portion that connects to a catheter and/or a fluid line attached to the catheter. A contact surface is located on an underside of the housing and positions the patient access site securement system on the patient. A first reservoir with an interior holds a liquid and transitions from a first state to a second state. The interior is in fluid communication with the inlet when the reservoir is in the second state to allow the liquid to flow from the inlet, through the internal fluid path and exit the outlet. The liquid interacts with the contact surface and/or the patient to alter a level of securement between the catheter and the patient.Type: GrantFiled: February 28, 2022Date of Patent: June 18, 2024Assignee: NP Medical Inc.Inventors: Todd M. Chelak, Andrew Galanis, Jonathan Gabel
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Patent number: 12005242Abstract: A needle shield assembly for use with a needle assembly is disclosed. The needle shield assembly includes an elongate needle shield comprising a shield portion, a hub connection portion and a bridge portion including a living hinge having a thickness. The bridge portion joins the hub connection portion and the shield portion. The hub connection portion includes a partially circular receiving ring having a diameter sized to frictionally receive a flange of a hub of the needle assembly. The shield portion includes two longitudinal walls defining a cavity and a needle assembling receiving cavity between the two longitudinal walls defining a recess. The shield portion is configured to pivot from an open position in which a needle cannula is exposed, to a closed needle protecting position in which a distal end of the needle cannula is within the longitudinal opening of the shield.Type: GrantFiled: February 18, 2021Date of Patent: June 11, 2024Assignee: Becton, Dickinson and CompanyInventors: Kevin M. Ryan, Angela Huenerfauth
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Patent number: 11992667Abstract: The present invention provides a curved needle design which deflects to an advantageous angle when inserted within the medial posterior soft tissue of the patient lower jaw. The deflected needle tip is more perpendicular to the vertical wall of the posterior ramus and promotes the needle tip contacting bone proximate to the inferior alveolar nerve prior to injection of anesthetic. The needle design also improves the tactile feedback to the dental practitioner as the needle penetrates tissue and contacts bone.Type: GrantFiled: April 14, 2020Date of Patent: May 28, 2024Inventor: Jelani T. Washington
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Patent number: 11980747Abstract: Implementations of the present disclosure are directed to an injection device (102) including a medicament reservoir (103) configured to store a medicament to be expelled by the injection device (102), an acoustic source (122a, 122b, 122c, 122d, 200, 300, 400) configured to generate an acoustic signal including information indicative of an amount of the medicament stored in the medicament reservoir (103), the acoustic signal being transmitted to an external device (104) configured to process the acoustic signal and to extract injection device data.Type: GrantFiled: February 21, 2023Date of Patent: May 14, 2024Assignee: SanofiInventors: Matthias Felber, Nathanael Wettstein, August Enzler, Felix Kramer
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Patent number: 11975178Abstract: A resin syringe includes: a syringe body made of polyolefin, and a printing layer having a shape that extends in a band around an outer surface of the syringe body. The printing layer comprises components including chlorinated polypropylene having a degree of chlorination in a range of 15 to 30%, a colorant, and a filler. A plurality of recessed portions is formed in the outer surface of the syringe body on which the printing layer is printed and the recessed portions form a shape that extends in a band around the outer surface of the syringe body and that is entirely covered by the printing layer. Each of the recessed portions has a depth of 50 nm or more and less than 1 ?m and a width of 50 nm or more and less than 1 ?m and is filled with at least one of the components of the printing layer.Type: GrantFiled: May 16, 2023Date of Patent: May 7, 2024Assignee: TERUMO KABUSHIKI KAISHAInventors: Shingo Koyama, Kaori Enomoto
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Patent number: 11969566Abstract: An apparatus, assembly, and method for controlling release of a drug from a drug-eluting balloon during delivery of a drug-eluting balloon to a situs within a body. More particularly, the present invention relates to a diametrically expandable sleeve having a first non-diametrically unexpanded state in which drug retained on or in a drug-eluting balloon is protected from release by a sleeve and a second diametrically expanded state in which drug retained on or in the drug-eluting balloon is exposed for focal release in the body by diametric expansion of the sleeve, exposing openings in the sleeve during diametric expansion and closing the openings in the sleeve when the sleeve is in its diametrically unexpanded state.Type: GrantFiled: June 7, 2023Date of Patent: April 30, 2024Assignee: Vactronix Scientific, LLCInventors: Christian G. Palmaz, Julio C. Palmaz, Scott P. Carpenter
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Patent number: 11957878Abstract: The invention provides methods and apparatus for injecting a medicine, especially a highly viscous medicine. Conventional methods and apparatus for injecting viscous medicines suffers suffer from a variety of problems such as excessive force during the initial needle insertion and initial injection. In an inventive method, during the initial phase of the injection, energy is stored in a torsion spring that is subsequently released during a later stage of the injection. The present invention also provides for an improved autoinjector; especially via the use of a combination compression and torsion spring that powers the injection through controlling force applied to a plunger via a screw flange or nut having pins that ride in a prescribed path down the length of the autoinjector.Type: GrantFiled: June 8, 2021Date of Patent: April 16, 2024Assignee: Battelle Memorial InstituteInventors: William G. Atterbury, Douglas E. Boyd
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Patent number: 11944730Abstract: The present invention relates to a breast status determination device (10?). The breast status determination device (10?) comprises a breast shield (16?), a nipple elongation measurement unit (17?), and a breast status determination unit (20?). The breast shield (16?) can receive abreast (12) of a user (14) therein. The nipple elongation measurement unit (17?) can measure an elongation of a nipple of the breast (12) received in the breast shield (16?) for a specific pressure in the breast shield (16?) during a milk extraction session. The breast status determination unit (20?) can determine a status of the breast (12) based on the elongation of the nipple (26). The breast status determination device (10?) can allow estimating of milk left in the breast during the milk extraction session, when the breast (12) is empty, and whether a milk ejection reflex is present or absent in the breast (12).Type: GrantFiled: January 11, 2019Date of Patent: April 2, 2024Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Yannyk Parulian Julian Bourquin, Lucja Elżbieta Segaar, Lili-Marjan Brockhuis
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Patent number: 11938307Abstract: A needle assembly for medical or surgical use is disclosed, such as for hemodialysis. A representative needle assembly comprises an outer needle assembly and an integral needle tip protector. A representative outer needle assembly comprises: an outer needle comprising: a first lumen; a first aperture with a sharp needle tip at a first distal end of the outer needle; and a second aperture arranged opposite the first aperture. In another embodiment, the outer needle has a longitudinal slot and the integral needle tip protector includes a sliding connector which is slidable in the longitudinal slot. The integral needle tip protector is arranged within the first lumen and moveable between a retracted configuration and an extended configuration, and comprises: a needle tip cover arranged to shield the sharp needle tip in the extended configuration, the needle tip cover having a smooth or beveled distal surface forming a blunt tip.Type: GrantFiled: February 10, 2023Date of Patent: March 26, 2024Inventor: Khaled Boubes
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Patent number: 11938282Abstract: A device for accommodating and magnetizing a tissue-penetrating medical device of various lengths, with or without a cover covering a portion or the entirety of the tissue-penetrating medical device, is disclosed including a sleeve member having an open proximal end, a distal end, an inner surface, an outer surface having a graduated injection depth gauge to indicate needle penetration depth when the cover is placed into a magnetizer, and a hollow body extending between the proximal end and the distal end to form a protective closure over a shaft of a tissue-penetrating medical device. A device having one or more magnetizing elements sectioned into a plurality of movable segments pivoting around an axis to accommodate needles with different lengths is also disclosed. Also disclosed is a device having one or more magnetizing means mounted on a movable element to magnetize needles of various lengths.Type: GrantFiled: July 7, 2022Date of Patent: March 26, 2024Assignee: Becton, Dickinson and CompanyInventors: Yiping Ma, S. Ray Isaacson, Jonathan Karl Burkholz, Brian Jensen, Daniel Robinaugh, Derek Sanchez
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Patent number: 11925771Abstract: A method of delivering a therapeutic agent to a nucleus pulposus of an intervertebral disc is provided. The method comprises inserting a delivery tool containing the therapeutic agent through an anterior portion, a lateral portion, or an anterolateral portion of an annulus fibrosus and into the nucleus pulposus of the intervertebral disc; and delivering the therapeutic agent to the nucleus pulposus of the intervertebral disc. Devices and kits are also provided.Type: GrantFiled: April 10, 2023Date of Patent: March 12, 2024Assignee: WARSAW ORTHOPEDIC, INC.Inventors: Benjamin T. Reves, Todd M. Boyce, Daniel A. Shimko, Jared T. Wilsey
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Patent number: 11904149Abstract: A closure assembly for a syringe or other medical administering device includes an outer sleeve having an access opening and a tip cap removably disposed therein. The tip cap includes a flow restrictor structured for removable, flow restricting connection to the syringe. An indicator member is removably connected within the outer sleeve, in interruptive relation to passage of the tip cap through the access opening. A retaining structure is fixedly connected to the flow restrictor and movable therewith relative to the indicator member. The retaining structure and flow restrictor are collectively structured for retaining engagement of the tip cap with the indicator member, as the tip and indicator member are concurrently removed from the outer sleeve and as the tip cap is disconnected from the flow restricting connection with the syringe.Type: GrantFiled: February 18, 2021Date of Patent: February 20, 2024Inventors: Jonathan Vitello, Peter Lehel
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Patent number: 11904151Abstract: The present disclosure relates to a cap for an injection device. The injection device comprises a body for holding a syringe having a needle extending from an end thereof. The cap is removably attachable to the body. The cap comprises an actuator and a needle shield to cover said needle. The cap further comprises a coupling between the actuator and the needle shield. The coupling is configured such that when the cap is attached to the body of the injection device axial movement of the actuator away from the body causes rotation of the needle shield relative to the body.Type: GrantFiled: June 14, 2021Date of Patent: February 20, 2024Assignee: Sanofi-Aventis Deutschland GMBHInventors: Stefan Wendland, Michael Harms