Abstract: This disclosure describes compounds of the formula ##STR1## where R.sub.1 is straight chain alkyl, andR.sub.2 is hydrogen, halo having an atomic weight of about 19 to 36, lower alkoxy or trifluoromethyl,Which are useful as minor tranquilizers and sleep inducers.

Abstract: Compounds having the formula ##STR1## in which R is alkyl, haloalkyl, cycloalkyl, cycloalkenyl, phenyl, optionally substituted by chlorine, methyl or methoxy, moreover bicycloheptyl or bicycloheptenyl; R.sub.1 is alkyl, optionally substituted by halogen, nitro, cyano or a radical having the formula ##STR2## ALKENYL, OPTIONALLY SUBSTITUTED BY HALOGEN; ALKINYL, ALKOXYALKYL, ALKYLMERCAPTO-ALKYL, CYCLOALKYL, PHENYL, HALOPHENYL, TRIFLUOROMETHYLPHENYL, BENZYL OR A RADICAL HAVING THE FORMULA ##STR3## R.sub.2 is alkyl, alkoxyalkyl, phenyl or halophenyl, R.sub.3 is methyl or ethyl, and X and Y are oxygen or sulfur are valuable pesticides.

Abstract: Certain 3-(4-chromanylamino)-2-oxazolidinones are useful as gastric antisecretory agents.

Abstract: A product obtained by reacting an alkanolamine represented by the formula ##STR1## where R is methyl, ethyl or hydroxymethyl and R.sup.2 is hydrogen, methyl or hydroxymethyl, with oiticica oil at ambient temperatures or above having utility as a dispersing agent in water-based paints.

Abstract: Insecticidally active compounds are disclosed, defined by the general formula ##STR1## in which R is hydrogen or methyl;R.sup.1 is hydrogen or methyl;R.sup.2 is a member selected from the group consisting of methyl, methoxy, ethyl, and ethoxy;R.sup.3 is alkoxy having 1 to 6 carbon atoms; andX is oxygen or sulfur.

Abstract: A one-step process for the preparation of 2,4-dihaloquinazolines is disclosed beginning with methoxycarbonyl- or phenoxycarbonyl-derivatives of substituted phenylureas which are cyclized and concomitantly halogenated with a cyclizing-halogenating reagent such as N,N-dimethylaniline in phosphorus oxychloride. The 2,4-dihaloquinazolines of the instant process are particularly valuable as intermediates in the preparation of 4-amino-2-(4-substituted-piperazin-1-yl) quinazolines useful in the treatment of cardiovascular disorders such as hypertension.

Abstract: 2-[4-(Polyhalo-2-hydroxy-2-propyl)anilino]-2-oxazolin-4-ones and the thiazolin-4-ones corresponding thereto, having useful anti-hypertensive properties, are disclosed herein. The compounds are prepared by reaction of the appropriate 4-(polyhalo-2-hydroxy-2-propyl)aniline with a .beta.-chloroethanoyl isocyanate or isothiocyanate and then cyclization of the resultant intermediate.

Abstract: Cyclopropylmethylamines which are substituted on the 2-position of nitrogen heterocycles so as to provide new compounds of the formula ##STR1## wherein A is oxygen, sulfur, or nitrogen; the other "R" variables in general are hydrogen, lower-alkyl, cyclopropyl, or lower-alkyl substituted cyclopropyl; and the n's are the numbers 0 to 3, inclusive, and acid addition salts thereof, are disclosed. The compounds are cardiovascular agents, which are depressive of the central nervous system. Their effects include hypnosis, analgesia, and neuro-modulation. They can be used as anti-hypertensive agents.

Abstract: The dextrorotatory and levorotatory isomers of 1,6-Carbamate-3N-carbethoxy-2,5-dideoxystreptamine (I) have been found to be very valuable intermediates useful in the preparation of totally synthetic aminoglycoside antibiotics. An example of such an aminoglycoside antibiotic is 5-deoxykanamycin A.

Abstract: Benzoxazoles substituted in the 2-position with sulfhydryl or halogen and substituted in the 5- or 6-position with an acetic or propionic acid group or a salt or ester thereof or a nitrile convertible thereto useful as intermediates in the preparation of 5- or 6-Substituted benzoxazole propionic or acetic acid derivatives, substituted in the 2-position of the oxazole nucleus by a group of the formula AR.sup.4 wherein A is --CH.sub.2 --, --CO--, --CHOR--, or --NR--, wherein R is hydrogen, C.sub.1-6 alkyl or C.sub.2-7 acyl, and R.sup.4 is optionally substituted phenyl, useful as non-steroidal, non-narcotic, analgesic, antipyretic and anti-inflammatory agents.

Abstract: Thiuram sulfides of oxazolidines and thiazolidines are disclosed herein and shown to be useful as non-blooming accelerators in the vulcanization of ethylene-propylene-diene-terpolymers.

Abstract: The compounds of the formula: ##STR1## and salts and esters thereof are useful agents for the treatment of bacterial infections either alone or in combination with a penicillin or cephalosporin derivative. The preceding compounds may be prepared by the hydrogenation of a compound of the formula: ##STR2## wherein R is a hydrogen atom or an acyl group or a salt or ester thereof.

Abstract: A benzodiazepine derivative of the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkyl which may be a straight chain, branched chain or cyclic group and may also be substituted,R.sub.2 is halogen, free hydroxyl, esterified hydroxyl, etherified hydroxyl, nitrile, carboxyl or a derivative thereof or is thioalkyl, thioaryl or the group ##STR2## R.sub.3 and R.sub.4 in this group being the same or different and being hydrogen, acyl, aryl, alkyl, aralkyl, aryloxyalkyl which latter five groups may also be substituted, or wherein R.sub.3 and R.sub.4 are saturated or unsaturated, straight chain or branched alkyl and in which groups the several alkyl may be interconnected directly or through a hetero atom, which if the hetero atom is nitrogen may also be substituted, and in which formula I, A and B are phenyl or phenyl, substituted by nitro, trifluoromethyl, halogen, methylthio, alkyl or alkoxy; or a pharmaceutically acceptable acid addition salt of said benzodiazepine derivatives of formula I.

Abstract: Compounds of the formula ##STR1## IN WHICH R.sup.1 is hydrogen or alkyl having 1 to 4 carbon atoms and Y is hydrogen or chlorine, useful as insecticides.

Abstract: Compounds of the formula ##STR1## in which R is methyl, chlorine or bromine and Y is hydrogen or methyl, useful as insecticides.

Abstract: Insecticidally active compounds are disclosed, defined by the general formula ##STR1## in which R is alkyl or alkoxy each having 1 to 6 carbon atoms;R.sup.1 is alkoxy having 1 to 6 carbon atoms; andX is oxygen or sulfur.

Abstract: A series of 3-[(4-chromanylidene)amino]-2-oxazolidinones are useful as gastric antisecretory agents.

Abstract: Compounds of the formula ##STR1## wherein R is hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl of 2 to 4 carbon atoms, epoxide of 2 to 4 carbon atoms or alkyl of 1 to 4 carbon atoms substituted by 1 or 2 halogen atoms, hydroxyl, etherified or acylated hydroxyl of 1 to 7 carbon atoms, azido, phthaliamido, SR.sup.1, SOR.sup.1 or SO.sub.2 R.sup.1 wherein R.sup.1 is aryl, are useful for their .beta.-lactamase inhibitory activity and their antibacterial activity.

Abstract: A method for the production of 2-[(2-hydroxymethyl)phenyl]-2-oxazolines by condensing o-phthalaldehyde with an alkanolamine represented by the formula ##STR1## where R is an alkyl group of 1 to 3 carbon atoms and R.sup.1 is hydrogen or methyl. The compounds have utility as tranquilizing agents.

Abstract: 3-Acylisoxazolines are prepared by reacting an alkene with an alpha-nitroketone in the presence of an organic acid catalyst.