Abstract: A method, including providing an electrical current to an electrode contact located in a cochlea of a human to evoke a hearing percept, and managing flow of perilymph located inside the cochlea locally to the electrode contact while the current is provided to the electrode contact. In an exemplary embodiment, the management is executed using a seal.

Abstract: The invention provides a seismocardiograph system, which includes an accelerometer, adapted to obtain accelerometer data from user, and a bandpass filter, adapted to filter the accelerometer data. The system further includes an envelope filter, adapted to suppress S2 peaks in the band pass filtered accelerometer data, wherein the envelope filter comprises: a low-pass filter; and a comb filter, wherein the delay of the comb filter is tuned to a left ventricle ejection time (LVET).

Abstract: A device for calculating cardiovascular heartbeat information is configured to receive an electronic audio signal with information representative of a human voice signal in the time-domain, the human voice signal comprising a vowel audio sound of a certain duration and a fundamental frequency; generate a power spectral profile of a section of the electronic audio signal, and detect the fundamental frequency (F0) in the generated power spectral profile; filter the received audio signal within a band around at least the detected fundamental frequency (F0) and thereby generating a denoised audio signal; generate a time-domain intermediate signal that captures frequency, amplitude and/or phase of the denoised audio signal; detect and calculate heartbeat information within a human cardiac band in the intermediate signal.

Abstract: A wearable, multiphasic cardioverter defibrillator system and method are provided.

Abstract: A method for synchronizing operation of a heart assist pump device to a patient's cardiac cycle includes obtaining a signal from a motor of a heart assist pump device and filtering the signal to remove noise. The method also includes determining a speed synchronization start point at which time the motor of the heart assist pump device will begin a change in speed of operation based on the filtered signal. The method further includes modulating a speed of the motor of the heart assist pump device to a target speed at the speed synchronization start point, thereby synchronizing the change in speed of operation with a patient's cardiac cycle.

Abstract: Methods and systems for facilitating assessment of blood flow in a tissue volume of a subject are disclosed. In some variations, the method may include: after a predetermined amount of a fluorescence agent has been administered to the subject, exciting the fluorescence agent in the tissue volume such that the excited fluorescence agent emits fluorescent light, acquiring fluorescence data based on the fluorescent light emitted during blood flow through the tissue volume, estimating a molar concentration of the fluorescence agent in the blood flowing through the tissue volume, and generating an assessment of blood flow in the tissue volume based at least in part on the fluorescence data and the estimated molar concentration of the fluorescence agent. The estimated molar concentration may be based on the predetermined amount of the fluorescence agent and an estimated circulating blood volume of the subject.

Abstract: The present invention relates to surgical dissection tips comprising a substrate comprising beryllium copper and a ferromagnetic layer coating at least a portion of the substrate, and methods of making such surgical dissection tips.

Abstract: A wearable medical monitoring device includes a plurality of ECG electrodes configured to receive an ECG signal when the wearable medical monitoring device is worn by a patient, and a monitor coupled to the plurality of ECG electrodes. The monitor is configured to detect an impending cardiac event based on the received ECG signal of the patient. The device includes at least one processor configured to execute a plurality of instructions to implement an update manager configured to receive a software update corresponding to the at least one software module for the monitor, determine an event estimation of risk score for a predetermined period of time, cause an installation of the update when the event estimation of risk score indicates a low likelihood of an impending cardiac event, and cause a delay in the installation when the event estimation of risk score indicates a high likelihood of impending cardiac event.

Abstract: Systems and methods for monitoring patient vasoactivity are discussed. An exemplary patient monitor system includes a sensor circuit configured to generate a heart sound (HS) metric using a HS signal sensed from a patient, and a vasoactivity monitor configured to monitor vasoactivity, such as degree of vasoconstriction or vasodilation, using the HS metric. The system can provide the monitored vasoactivity to a user to alert patient hemodynamic responses to vasoactive drugs, or initiate or adjust a vasoactive therapy according to the vasoactivity. The system may use the monitored vasoactivity to detect a medical condition such as worsening heart failure, pulmonary edema, or syncope.

Abstract: There is provided herein a catheter for resecting an undesired tissue from a body of a subject, the catheter comprising a tip section in a shape of a cylinder or a cylinder's sector having a central longitudinal axis, the tip section comprising: a central longitudinal lumen; a first set of optical fibers configured to transmit laser radiation outside a distal extremity of the tip section, in a direction parallel to the central longitudinal axis; a second set of optical fibers configured to transmit laser radiation, transversely to the central longitudinal axis; wherein the first set of optical fibers and the second set of optical fibers are selectively operable to resect and/or ablate the undesired tissue.

Abstract: An assembly for enabling a caregiver to secure a physiological monitoring device to an arm of a user can include the physiological monitoring device a cradle configured to removably secure to the physiological monitoring device and to the user's arm. The physiological monitoring device can include a first connector port configured to electrically connect to a first cable and a first locking tab movable between an extended position and a retracted position. The cradle can include a base, first and second sidewalls, a back wall connected to the base and the first and second sidewalls. The cradle can further include a first opening in the back wall configured to receive the first connector port and a second opening in the first sidewall configured to receive the first locking tab when the physiological monitoring device is secured to the cradle and the first locking tab is in the extended position.

Abstract: A method for treating tissue through a branched luminal network of a patient is provided. A pathway to a point of interest in branched luminal network of a patient is generated. An extended working channel is advanced transorally into the branched luminal network and along the pathway to the point of interest. The extended working channel may be positioned in a substantially fixed orientation at the point interest. A tool is advanced though the extended working channel to the point of interest. Tissue at the point of interest is treated.

Abstract: Systems, methods, and devices allow percutaneous mapping, orientation and/or ablation in bodily cavities or lumens. Such may include a structure that is percutaneously positionable in a cavity, such as an intra-cardiac cavity of a heart. Transducers carried by the structure are responsive to blood flow. For example, the transducers may sense temperature, temperature being related to convective cooling caused by blood flow. A controller discerns positional information or location, based on signals from the transducers. For example, blood flow may be greater and/or faster proximate a port in cardiac tissue than proximate tissue spaced from the port. Position information may allow precise ablation of selected tissue, for example tissue surround a port in the intra-cardiac cavity.

Abstract: Methods, systems and devices for applying energy to tissue, and more particularly relates to a system for ablating or modifying structures in a body with systems and methods that generate a flow of vapor at a controlled flow rate for applying energy to the body structure.

Abstract: Maxillary devices and Mandibular devices each have a first housing connectable to a tooth of a user or connectable or integral with a teeth covering, wherein the housing encloses an on-board circuit board and a power source. The first housing of the maxillary devices has a tooth connecting portion, a palate housing portion and/or a buccal housing portion. The first housing of the mandibular devices has a tooth connecting portion and a sublingual portion. Each of the palate housing portion and the buccal housing portion enclose a stimulator having an electrode electrically connected to the on-board circuit board and the power source, and can enclose a sensor and/or a medicament dispenser. The sublingual portion encloses a sensor and a medicament dispenser each of which are in electrical communication with the microprocessor of the on-board circuit board.

Abstract: Lingual repositioning devices have a mandibular piece having a teeth covering and a first housing proximate either a left molar portion or a right molar portion of the teeth covering. The first housing includes a stimulator protrusion extending therefrom at a position to extend toward a tongue of a user and to contact a lingual muscle of the tongue or includes a sensor portion extending therefrom at a position to extend toward a tongue of a user and to be positioned under the tongue. The stimulator protrusion encloses a stimulator and the first housing encloses a power source electrically connected to a circuit board and electrically connected to an electrode of a stimulator. A second housing at the other of the left or right molar portions has a stimulator protrusion or a sensor portion. The first and second housings may be removably attachable to the teeth covering.

Abstract: So as to be able to determine the position of a functional element as precisely as possible during the invasive use of a blood pump in a patient's body without the use of imaging methods, the blood pump is connected to a main sensor which records signals of the patient's heart, which are compared to other electrophysiological heart signals recorded by several sensors distributed on the body surface so as to allow the position of the blood pump to be determined by way of linking.

Abstract: A method of detecting sleep apnea includes generating a cardiac signal indicating activity of a heart of a patient. The method further includes determining a short-term average heart rate and a long-term average heart rate. The method further includes determining a start and end of a heart rate cycle based on the short-term average heart rate and the long-term average heart rate. The method further includes determining physiological parameter values occurring during the heart rate cycle. The method further includes determining whether patient has or has not experienced a sleep apnea event based on whether one or more conditions are satisfied by one or more parameter values for one or more heart rate cycles and responsively generating an indication that patient has or has not experienced a sleep apnea event.

Abstract: An apparatus, including a sterilely sealed package, and an electrode assembly sterilely sealed in the package, wherein the apparatus is configured to enable testing for an open circuit between two electrodes of the electrode assembly with the electrode assembly sterilely sealed in the package.

Abstract: A device, such as an IMD, having a tissue conductance communication (TCC) transmitter controls a drive signal circuit and a polarity switching circuit by a controller of the TCC transmitter to generate an alternating current (AC) ramp on signal having a peak amplitude that is stepped up from a starting peak-to-peak amplitude to an ending peak-to-peak amplitude according to a step increment and step up interval. The TCC transmitter is further controlled to transmit the AC ramp on signal from the drive signal circuit and the polarity switching circuit via a coupling capacitor coupled to a transmitting electrode vector coupleable to the IMD. After the AC ramp on signal, the TCC transmitter transmits at least one TCC signal to a receiving device.