Abstract: Pesticidal 5-ethylamino-1-arylpyrazoles of the formula ##STR1## in which R.sup.1 represents hydrogen or alkyl,R.sup.2 represents halogenoalkyl andn represents a number 0, 1 or 2, with the proviso that if R.sup.1 represents hydrogen, R.sup.2 is not dichlorofluoromethyl and n is not 0.These compounds are not only active against plant, hygiene and stored product pests, but also, in the veterinary medicine sector, against animal parasites, such as scaly ticks, argasidae, scab mites, trombidae, flies (stinging and sucking), parasitic fly larvae, lice, hair lice, bird lice and fleas.
Type:
Grant
Filed:
June 2, 1988
Date of Patent:
March 13, 1990
Assignee:
Bayer Aktiengesellschaft
Inventors:
Uta Jensen-Korte, Otto Schallner, Jorg Stetter, Peter Andrews, Benedikt Becker, Bernhard Homeyer, Wilhelm Stendel, Wolfgang Behrenz
Abstract: Novel 1-(benzo[b]thienyl)-2-(thienyl)ethenes, processes for the preparation thereof, and methods of reducing inflammation utilizing compounds and compositions there are disclosed.
Abstract: A process for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains comprising reacting an oxophthalizinyl acetic acid ester with an aniline derivative is disclosed. Also disclosed are processes for the preparation of such oxopthalizinyl esters.
Type:
Grant
Filed:
May 19, 1989
Date of Patent:
February 13, 1990
Assignee:
Pfizer Inc.
Inventors:
Banavara L. Mylari, William J. Zembrowski
Abstract: Certain aryl-alkynoic, alkenoic and alkanoic acids and derivatives and their use in treating inflammation, allergy and hyperproliferative skin disease are disclosed.
Abstract: Organic amide compounds of the formula ##STR1## wherein R.sub.1 --CO is a residue of a carboxylic acid with the proviso that the carboxylic acid is not a natural fatty acid normally bound to nitrogen of nitrogenous lipids, R.sub.2 is a hydrogen atom, a C.sub.1-7 alkyl group, or a C.sub.4-7 cycloalkyl group, and R.sub.3-N is a residue of a nitrogenous lipid. The compounds are useful in increasing or stimulating the in vivo biological activity of in vitro biologically active carboxylic acids.
Abstract: Organic amide compounds of the formula ##STR1## wherein R.sub.1 --CO is a residue of a carboxylic acid with the proviso that the carboxylic acid is not a natural fatty acid normally bound to nitrogen of nitrogenous lipids, R.sub.2 is a hydrogen atom, a C.sub.1-7 alkyl group, or a C.sub.4-7 cycloalkyl group, and R.sub.3-N is a residue of a nitrogenous lipid. The compounds are useful in increasing or stimulating the in vivo biological activity of in vitro biologically active carboxylic acids.
Abstract: Thiophene derivatives of the general formula ##STR1## wherein R.sub.1 and R.sub.2, which may be the same or different, each are hydrogen or lower acyl and R.sub.6 is hydrogen or lower alkyl, are prepared by the reaction of a compound of the general formula ##STR2## wherein R.sub.3 is lower alkyl, R.sub.4 and R.sub.5 are lower acyl and X is chlorine, bromine or iodine, with a strong basic quaternary ammonium anion exchange resin in the monothiophosphate form to form a polymer intermediate product of the formula ##STR3## wherein R.sub.3, R.sub.4, and R.sub.5 have the significances given above, and (P).sup.+++ represents a polymer cation, which after purification in an acidic medium is reacted to the thiophene derivative of formula (I).The invention further relates to the novel polymer compound of formula (III) obtained in this process as an intermediate product.
Abstract: A compound of the formula: ##STR1## wherein E is an ethenyl group of the formula: ##STR2## in which X is H when Y is NO.sub.2 ;Y is H when X is NO.sub.2 ; orX is CN when Y is CNwhich has the capacity to form a crystal in which the molecules are aligned substantially in the same manner giving it non-linear optical properties. The crystalline product is thus adapted for use in devices exhibiting non-linear optical effects.
Abstract: This invention relates to new tetrahydrofurans and tetrahydrothiophenes of the general formula: ##STR1## wherein X stands for O or S, m is an integer from 1 to 12 and A is a pyridinium or an ammonium salt, to a preparation process of said compounds and to therapeutic compositions of matter containing the same.
Type:
Grant
Filed:
May 27, 1988
Date of Patent:
December 19, 1989
Assignee:
Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
Abstract: A substituted carboxylic acid derivative which is fungicidally active is provided. The compound has the formula: ##STR1## wherein R.sub.1 stands for a methyl or ethyl group, A stands for ##STR2## R.sub.2 stands for a methyl, ethyl or trifluoromethyl group, R.sub.3 stands for a methyl group or a halogen or hydrogen atom, R.sub.4 stands for a fluorine or hydrogen atom, R.sub.5 stands for a methyl, nitro or trifluoromethyl group or a halogen atom, Z stands for a .dbd.CH-- group or an N atom, R.sub.6 stands for a methyl, ethyl or trifluoromethyl group and R.sub.7 stands for an amino or methyl group or a chlorine atom.
Abstract: A method of manufacturing N-alkyl-N'-methyl-alkyleneureas, by reacting an alkyleneurea with formaldehyde to produce a hydroxymethyl-alkyleneurea, and further reacting said hydroxymethyl-alkyleneurea with formic acid to yield a N-alkyl-N'-methyl-alkyleneurea product, wherein the molar ratio of the N-alkyl-N'-hydroxymethyl-alkyleneureas or N,N'-(bis)hydroxymethyl-alkyleneureas is from 1-2 to 1-10, preferably 1-4 to 1-7.
Abstract: Novel heterocyclic compounds shown by the general formula ##STR1## or the pharmaceutically acceptable salts thereof useful as medicament in particular as antagonist of slow reacting substance of anaphylaxis (SRS-A).
Abstract: The present invention relates to a class of 5-haloalkyl-3-hydroxy-1-(C.sub.1-2 alkyl)pyrazoles useful as precursors for an active class of phenoxypyrazole herbicides.
Type:
Grant
Filed:
April 13, 1988
Date of Patent:
August 8, 1989
Assignee:
Monsanto Company
Inventors:
Len F. Lee, Kurt Moedritzer, Michael D. Rogers
Abstract: There are disclosed compounds of the formula ##STR1## where R.sub.1 is loweralkoxycarbonyl, --CH.sub.2 OH or --CONR.sub.3 R.sub.4, R.sub.3 and R.sub.4 being independently hydrogen, loweralkyl or arylloweralkyl; and R.sub.2 is --CH.sub.2 CH.dbd.CH.sub.2, ##STR2## R.sub.5 and R.sub.6 being independently loweralkyl or alternatively the group -NR.sub.5 R.sub.6 as a whole being ##STR3## R.sub.7 being hydrogen, loweralkyl or arylloweralkyl; which are useful for enhancing cholinergic activity in mammals and hence for the treatment of various memory dysfunctions characterized by decreased cholinergic function such as Alzheimer's disease.