Patents Examined by Richard Sharpe
  • Patent number: 4908377
    Abstract: Pesticidal 5-ethylamino-1-arylpyrazoles of the formula ##STR1## in which R.sup.1 represents hydrogen or alkyl,R.sup.2 represents halogenoalkyl andn represents a number 0, 1 or 2, with the proviso that if R.sup.1 represents hydrogen, R.sup.2 is not dichlorofluoromethyl and n is not 0.These compounds are not only active against plant, hygiene and stored product pests, but also, in the veterinary medicine sector, against animal parasites, such as scaly ticks, argasidae, scab mites, trombidae, flies (stinging and sucking), parasitic fly larvae, lice, hair lice, bird lice and fleas.
    Type: Grant
    Filed: June 2, 1988
    Date of Patent: March 13, 1990
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uta Jensen-Korte, Otto Schallner, Jorg Stetter, Peter Andrews, Benedikt Becker, Bernhard Homeyer, Wilhelm Stendel, Wolfgang Behrenz
  • Patent number: 4904674
    Abstract: Novel 1-(benzo[b]thienyl)-2-(thienyl)ethenes, processes for the preparation thereof, and methods of reducing inflammation utilizing compounds and compositions there are disclosed.
    Type: Grant
    Filed: August 16, 1989
    Date of Patent: February 27, 1990
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Lawrence L. Martin, Joseph F. Payack
  • Patent number: 4900844
    Abstract: A process for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains comprising reacting an oxophthalizinyl acetic acid ester with an aniline derivative is disclosed. Also disclosed are processes for the preparation of such oxopthalizinyl esters.
    Type: Grant
    Filed: May 19, 1989
    Date of Patent: February 13, 1990
    Assignee: Pfizer Inc.
    Inventors: Banavara L. Mylari, William J. Zembrowski
  • Patent number: 4897397
    Abstract: Certain aryl-alkynoic, alkenoic and alkanoic acids and derivatives and their use in treating inflammation, allergy and hyperproliferative skin disease are disclosed.
    Type: Grant
    Filed: December 16, 1988
    Date of Patent: January 30, 1990
    Assignee: Schering Corporation
    Inventors: Neng Y. Shih, David J. Blythin
  • Patent number: 4897381
    Abstract: Organic amide compounds of the formula ##STR1## wherein R.sub.1 --CO is a residue of a carboxylic acid with the proviso that the carboxylic acid is not a natural fatty acid normally bound to nitrogen of nitrogenous lipids, R.sub.2 is a hydrogen atom, a C.sub.1-7 alkyl group, or a C.sub.4-7 cycloalkyl group, and R.sub.3-N is a residue of a nitrogenous lipid. The compounds are useful in increasing or stimulating the in vivo biological activity of in vitro biologically active carboxylic acids.
    Type: Grant
    Filed: June 21, 1988
    Date of Patent: January 30, 1990
    Assignee: Fidia S.p.A.
    Inventors: Francesco della Valle, Aurelio Romeo
  • Patent number: 4897382
    Abstract: Organic amide compounds of the formula ##STR1## wherein R.sub.1 --CO is a residue of a carboxylic acid with the proviso that the carboxylic acid is not a natural fatty acid normally bound to nitrogen of nitrogenous lipids, R.sub.2 is a hydrogen atom, a C.sub.1-7 alkyl group, or a C.sub.4-7 cycloalkyl group, and R.sub.3-N is a residue of a nitrogenous lipid. The compounds are useful in increasing or stimulating the in vivo biological activity of in vitro biologically active carboxylic acids.
    Type: Grant
    Filed: June 21, 1988
    Date of Patent: January 30, 1990
    Assignee: Fidia S.p.A.
    Inventors: Francesco della Valle, Aurelio Romeo
  • Patent number: 4894463
    Abstract: Thiophene derivatives of the general formula ##STR1## wherein R.sub.1 and R.sub.2, which may be the same or different, each are hydrogen or lower acyl and R.sub.6 is hydrogen or lower alkyl, are prepared by the reaction of a compound of the general formula ##STR2## wherein R.sub.3 is lower alkyl, R.sub.4 and R.sub.5 are lower acyl and X is chlorine, bromine or iodine, with a strong basic quaternary ammonium anion exchange resin in the monothiophosphate form to form a polymer intermediate product of the formula ##STR3## wherein R.sub.3, R.sub.4, and R.sub.5 have the significances given above, and (P).sup.+++ represents a polymer cation, which after purification in an acidic medium is reacted to the thiophene derivative of formula (I).The invention further relates to the novel polymer compound of formula (III) obtained in this process as an intermediate product.
    Type: Grant
    Filed: August 16, 1988
    Date of Patent: January 16, 1990
    Inventor: Holger Blum
  • Patent number: 4894186
    Abstract: A compound of the formula: ##STR1## wherein E is an ethenyl group of the formula: ##STR2## in which X is H when Y is NO.sub.2 ;Y is H when X is NO.sub.2 ; orX is CN when Y is CNwhich has the capacity to form a crystal in which the molecules are aligned substantially in the same manner giving it non-linear optical properties. The crystalline product is thus adapted for use in devices exhibiting non-linear optical effects.
    Type: Grant
    Filed: September 23, 1988
    Date of Patent: January 16, 1990
    Assignee: Imperial Chemical Industries PLC
    Inventors: Paul F. Gordon, Brian Bothwell
  • Patent number: 4888338
    Abstract: This invention relates to new tetrahydrofurans and tetrahydrothiophenes of the general formula: ##STR1## wherein X stands for O or S, m is an integer from 1 to 12 and A is a pyridinium or an ammonium salt, to a preparation process of said compounds and to therapeutic compositions of matter containing the same.
    Type: Grant
    Filed: May 27, 1988
    Date of Patent: December 19, 1989
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Jean-Jacques Godfroid, Pierre Braquet
  • Patent number: 4885022
    Abstract: A pyrazole derivative having the formula: ##STR1## where A, B, X, Y, Z and Q are described below.
    Type: Grant
    Filed: November 18, 1987
    Date of Patent: December 5, 1989
    Assignee: Nissan Chemical Industries Ltd.
    Inventors: Masatoshi Baba, Takuya Kakuta, Norio Tanaka, Eiichi Oya, Takashi Ikai, Tsutomu Nawamaki, Shigeomi Watanabe
  • Patent number: 4877441
    Abstract: A substituted carboxylic acid derivative which is fungicidally active is provided. The compound has the formula: ##STR1## wherein R.sub.1 stands for a methyl or ethyl group, A stands for ##STR2## R.sub.2 stands for a methyl, ethyl or trifluoromethyl group, R.sub.3 stands for a methyl group or a halogen or hydrogen atom, R.sub.4 stands for a fluorine or hydrogen atom, R.sub.5 stands for a methyl, nitro or trifluoromethyl group or a halogen atom, Z stands for a .dbd.CH-- group or an N atom, R.sub.6 stands for a methyl, ethyl or trifluoromethyl group and R.sub.7 stands for an amino or methyl group or a chlorine atom.
    Type: Grant
    Filed: October 18, 1988
    Date of Patent: October 31, 1989
    Assignee: Sumitomo Chemical Company Ltd.
    Inventors: Tatsuya Mori, Tadashi Ohsumi, Shigeo Nakamura, Kiyoto Maeda, Sumio Nishida, Hirotaka Takano
  • Patent number: 4864026
    Abstract: A method of manufacturing N-alkyl-N'-methyl-alkyleneureas, by reacting an alkyleneurea with formaldehyde to produce a hydroxymethyl-alkyleneurea, and further reacting said hydroxymethyl-alkyleneurea with formic acid to yield a N-alkyl-N'-methyl-alkyleneurea product, wherein the molar ratio of the N-alkyl-N'-hydroxymethyl-alkyleneureas or N,N'-(bis)hydroxymethyl-alkyleneureas is from 1-2 to 1-10, preferably 1-4 to 1-7.
    Type: Grant
    Filed: January 15, 1988
    Date of Patent: September 5, 1989
    Assignee: HULS Aktiengesellschaft
    Inventors: Peter Bickert, Hans Bellut
  • Patent number: 4855310
    Abstract: Novel heterocyclic compounds shown by the general formula ##STR1## or the pharmaceutically acceptable salts thereof useful as medicament in particular as antagonist of slow reacting substance of anaphylaxis (SRS-A).
    Type: Grant
    Filed: March 25, 1988
    Date of Patent: August 8, 1989
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Kiyoshi Murase, Toshiyasu Mase, Hiromu Hara, Kenichi Tomioka
  • Patent number: 4855442
    Abstract: The present invention relates to a class of 5-haloalkyl-3-hydroxy-1-(C.sub.1-2 alkyl)pyrazoles useful as precursors for an active class of phenoxypyrazole herbicides.
    Type: Grant
    Filed: April 13, 1988
    Date of Patent: August 8, 1989
    Assignee: Monsanto Company
    Inventors: Len F. Lee, Kurt Moedritzer, Michael D. Rogers
  • Patent number: 4833139
    Abstract: There are disclosed compounds of the formula ##STR1## where R.sub.1 is loweralkoxycarbonyl, --CH.sub.2 OH or --CONR.sub.3 R.sub.4, R.sub.3 and R.sub.4 being independently hydrogen, loweralkyl or arylloweralkyl; and R.sub.2 is --CH.sub.2 CH.dbd.CH.sub.2, ##STR2## R.sub.5 and R.sub.6 being independently loweralkyl or alternatively the group -NR.sub.5 R.sub.6 as a whole being ##STR3## R.sub.7 being hydrogen, loweralkyl or arylloweralkyl; which are useful for enhancing cholinergic activity in mammals and hence for the treatment of various memory dysfunctions characterized by decreased cholinergic function such as Alzheimer's disease.
    Type: Grant
    Filed: July 5, 1988
    Date of Patent: May 23, 1989
    Assignee: Hoechst-Roussel Pharmaceuticals, Inc.
    Inventor: Lawrence L. Martin