Patents Examined by Robert H. Harrison
  • Disinfection of air using an iodine/resin disinfectant
    Patent number: 5980827
    Abstract: The present invention relates to iodine demand disinfectants. It relates in particular to a process for preparing a polyiodide-resin for use as an iodine demand disinfectant wherein a porous strong base anion exchange resin in a salt form, is contacted with a material capable of donating a member absorbable by the resin so as to convert the resin to the polyiodide-resin. The adsorbable member is selected from the group comprising I.sub.2 and polyiodide ion having a valence of -1. The process is characterized in that conversion of the anion exchange resin to the polyiodide-resin is effected at elevated temperature and elevated pressure, the elevated temperature being 100 degrees C. or higher, the elevated pressure being greater than atmospheric pressure. The present invention also relates to disinfectant substance comprising an iodine (impregnated) resin as produced by the above process.
    Type: Grant
    Filed: February 24, 1997
    Date of Patent: November 9, 1999
    Inventor: Pierre Jean Messier
  • Thrombolytic agents and methods of treatment for thrombosis
    Patent number: 5980950
    Abstract: The foregoing invention relates to a new microbubble preparation and thrombolytic therapy which relies on microbubbles and ultrasound for its lytic activity. The pharmaceutical composition of the invention comprises a liquid solution of microbubbles with an internal atmosphere enhanced with the perfluorocarbon gas which cavitate in the presence of an ultrasound field following intravenous injection or infusion of said composition into said host. For thrombolysis the area of a thrombus is exposed to an ultrasound field in the presence of the microbubbles and significant lysis is experienced. The method and pharmaceutical composition of the invention exhibit thrombolytic properties similar to those of other thrombolytic agents such as urokinase and are less toxic and are clot specific in that they do not introduce a systemic lytic state to a said animal.
    Type: Grant
    Filed: April 3, 1997
    Date of Patent: November 9, 1999
    Assignee: The Board of Regents of the University of Nebraska
    Inventor: Thomas R. Porter
  • Cosmetic skin-care product against ageing of the skin as an effect of light
    Patent number: 5972315
    Abstract: The present invention relates to a new cosmetic skin-care product for external use, which is based on UV-radiation-absorbing substances in combination with a free-radical scavenger system.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: October 26, 1999
    Assignee: Sara Lee/DE N.V.
    Inventors: Eckart Voss, Peter Finkel
  • Ultrafine particle power for inhalation and method for production thereof
    Patent number: 5972388
    Abstract: An ultrafine particle powder for inhalation to be delivered mainly to a lower airway, containing specific cellulose lower alkyl ethers and a medicament, at least 80% of the powder having a particle size in the range of 0.5 to 10 .mu.m.
    Type: Grant
    Filed: January 7, 1997
    Date of Patent: October 26, 1999
    Assignee: Teijin Limited
    Inventors: Kiyoyuki Sakon, Masahiro Sakagami, Yuji Makino, Yoshiki Suzuki, Hideki Kobayashi
  • Fire-resistant glass fiber products
    Patent number: 5972434
    Abstract: Fire resistant glass fiber products are produced by coating the glass fibers with at least one nitrogen containing compound and at least 10 weight percent of at least one boron containing compound, drying the glass fibers and curing a binder that is in the coating. The nitrogen containing compound(s) are present in sufficient amounts that there is at least one mol or atom of nitrogen present for each mol or atom of boron present in the boron containing compound(s). When the product is exposed to a fire or high temperatures, such as about 1000 degrees F. or higher, the nitrogen released from the nitrogen containing compound(s) reacts with boron or boron oxide to form a sheath of refractory material around the fibers that protects the fibers and allows the fibers to maintain integrity to higher temperatures and/or for longer times than untreated fibers.
    Type: Grant
    Filed: September 29, 1998
    Date of Patent: October 26, 1999
    Assignee: Johns Manville International, Inc.
    Inventor: Richard Emil Kajander
  • Compositions containing dialkyl (C.sub.1 -C.sub.6)-ketone peroxide for the preservation of animal and human dead tissues
    Patent number: 5968497
    Abstract: The compositions for the preservation of organic tissues are comprised of a mixture from 12 to 70% of at least one dialkyl (C.sub.1 -C.sub.6)-keton peroxide, from 10 to 15% of glycerine, from 10 to 70% of at least one alcohol and, optionally, from 0 to 10% of a complementary marking, coloring and/or aromatic agent. Said compositions may be mixed with other appropriate agents or diluents, and can be applied especially to the preservation of tissues of all types, of human or origin, preferably by embalming or immersion.
    Type: Grant
    Filed: February 18, 1997
    Date of Patent: October 19, 1999
    Assignee: Universidad Complutense de Madrid
    Inventors: Juan Jimenez Collado, Edgar Arene Rada, Ramon Chavez Inzunza
  • Method and system for treating damaged hair
    Patent number: 5964227
    Abstract: The present invention provides a process of treating damaged hair and a system of formulations for carrying out the process. Treatment according to the invention incorporates protein into the structure of damaged hair by the use of an aqueous solution including an acid and a positively charged electrolyte.
    Type: Grant
    Filed: October 15, 1997
    Date of Patent: October 12, 1999
    Assignee: Texturizer, Inc.
    Inventor: Steven Joseph Collin
  • Substained release compositions and a method of preparing pharmaceutical compositions
    Patent number: 5965163
    Abstract: A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form agglomerates, breaking the agglomerates to give controlled release particles and optionally continuing the mechanical working with the optional addition of a low percentage of the carrier or diluent.
    Type: Grant
    Filed: September 30, 1997
    Date of Patent: October 12, 1999
    Assignee: Euro-Celtique, S.A.
    Inventors: Ronald Brown Miller, Stewart Thomas Leslie, Sandra Therese Antoinette Malkowska, Derek Allan Prater, Trevor John Knott, Joanne Heafield, Deborah Challis
  • Amorphous silicas
    Patent number: 5964937
    Abstract: An amorphous silica having an RDA value of between 30 and 70, an oil absorption capacity of between 100 and 155 cc/100 g and a moisture loss of less than 7% w/w, can be incorporated at a 10% to 25% loading into a transparent toothpaste having a refractive index of above 1.445, this toothpaste having an RDA value of between 30 and 60.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: October 12, 1999
    Assignee: Crosfield Limited
    Inventor: Peter William Stanier
  • Azapeptide derivative
    Patent number: 5965538
    Abstract: Disclosed is an azapeptide derivative represented by the formula (I): ##STR1## wherein A represents a direct bond, an .alpha.-amino acid or a residue of a dipeptide; R.sup.1 represents a hydrogen atom or a protective group for a terminal amino group; R.sup.2 represents a phenyl group or a phenyl group substituted by one or two substituents selected from the group consisting of a lower alkyl group, halogen atom, hydroxyl group which may be protected, nitro group, amino group which may be protected and perhalo lower alkyl group; and R.sup.3 represents a hydroxyl group or a protective group for a terminal carboxyl group,and a salt thereof, and an agent for curing nervous inflammation of respiratory apparatus, asthma and bronchospasm comprising the azapeptide derivative represented by the formula (I) or a salt thereof as an active ingredient.
    Type: Grant
    Filed: August 24, 1998
    Date of Patent: October 12, 1999
    Assignee: Fujirebio Inc.
    Inventors: Yoshiharu Nakashima, Michiyo Hizuka, Yasushi Higashide, Tetsuaki Yamaura, Hiroshi Ikawa
  • Use of alum to inhibit ammonia volatilization and to decrease phosphorous solubility in poultry litter
    Patent number: 5961968
    Abstract: A method for treating poultry litter which inhibits ammonia volatilization and reduces soluble phophorus levels in the litter. The method comprises the addition of alum to litter in an amount sufficient to maintain the litter pH at values low enough to inhibit ammonia volatilization. The addition of alum, iron or calcium compounds to litter also effectively precipitates soluble phosphorus in litter, thereby reducing the amount of soluble phosphorus runoff from fields receiving litter.
    Type: Grant
    Filed: May 1, 1996
    Date of Patent: October 5, 1999
    Assignees: Trustees of University of Arkansas, The United States of America as represented by the Secretary of Agriculture
    Inventor: Philip A. Moore, Jr.
  • Opioid formulations having extended controlled released
    Patent number: 5958459
    Abstract: Solid controlled-release oral dosage forms comprising a therapeutically effective amount of an opioid analgesic or a salt thereof which provide an extended duration of pain relief of about 24 hours, have a dissolution rate in-vitro of the dosage form, when measured by the USP Paddle Method of 100 rpm in 900 ml aqueous buffer at 37.degree. C. from about 12.5% to about 42.5% (by weight) active agent released after 1 hour, from about 25% to about 55% (by weight) active agent released after 2 hours, from about 45% to about 75% (by weight) opioid analgesic released after 4 hours and greater than about 60% (by weight) opioid analgesic released after 8 hours, the in-vitro release rate being substantially independent of pH and chosen such that the peak plasma level of active agent obtained in-vivo between about 2 and about 8 hours after administration of the dosage form.
    Type: Grant
    Filed: November 27, 1995
    Date of Patent: September 28, 1999
    Assignee: Purdue Pharma L.P.
    Inventors: Mark Chasin, Benjamin Oshlack, Frank Pedi, Jr.
  • Pesticidal compositions in paste form
    Patent number: 5951994
    Abstract: Novel pasty compositions for the control of animal pests and fungal diseases on plants, which compositions compriseat least one pesticidally active or fungicidally active compound andat least one adjuvant, which is solid, liquid or pasty at room temperature andoptionally, one or more excipients and water.
    Type: Grant
    Filed: September 30, 1997
    Date of Patent: September 14, 1999
    Assignee: Nihon Bayer Agrochem K. K.
    Inventors: Yuzuru Wada, Yuichi Otsu, Kunihiro Isono, Shigeharu Koyama, Shinzaburo Sone
  • Processes for preparing compositions for inhalation
    Patent number: 5952008
    Abstract: A pharmaceutical composition including a mixture of active compounds (A) a pharmaceutically active polypeptide, and (B) an enhancer compound which enhances the systemic absorption of the polypeptide in the lower respiratory tract of a patient, the mixture being in the form of a dry powder for inhalation in which at least 50% of the total mass of the active compounds consists of primary particles having a diameter less than or equal to about 10 microns, the primary particles optionally being formed into agglomerates.
    Type: Grant
    Filed: May 19, 1997
    Date of Patent: September 14, 1999
    Assignee: AB Astra
    Inventors: Kjell Goran Erik Backstrom, Carl Magnus Olof Dahlback, Peter Edman, Ann Charlotte Birgit Johansson
  • Stable hydroalcoholic compositions
    Patent number: 5951993
    Abstract: Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight wherein the composition free of auxiliary thickeners has a viscosity of at least 4,000 centipoise at 23 degrees C. and wherein each emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The composition is useful as a presurgical scrub replacement, a lotion or other hand preparation.
    Type: Grant
    Filed: January 9, 1997
    Date of Patent: September 14, 1999
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Matthew T. Scholz, Robert A. Asmus, Jill R. Charpentier
  • Drug preparations for treating impotency
    Patent number: 5952006
    Abstract: Topical gelled compositions comprising a drug for treating impotency dispersed within a polymer matrix and treatments using the complex.
    Type: Grant
    Filed: March 28, 1997
    Date of Patent: September 14, 1999
    Assignee: L.A.M. Pharmaceuticals, LLC
    Inventors: Alan Drizen, Peter Rothbart, Gary M. Nath
  • Microemulsion preparation containing a slightly absorbable substance
    Patent number: 5948825
    Abstract: Microemulsion preparation in which a plurality of specified surfactants are combined such that aqueous-phase droplets that contain a physiologically active substance of low absorption and which have an average size of 0.4-100 nm are dispersed in an oil-phase dispersion medium. In order to improve its low transdermic or transmucosal absorbability, the physiologically active substance is allowed to be present as dissolved in the aqueous-phase droplets in the W/O emulsion. The preparation is low in local irritation and uses neither malodorous substances such as higher alcohols nor conventional absorption enhancers.
    Type: Grant
    Filed: October 19, 1995
    Date of Patent: September 7, 1999
    Assignee: Institute for Advanced Skin Research Inc.
    Inventors: Masao Takahashi, Hiroshi Matsushita
  • Anhydrous cosmetic composition in the form of a soft paste and process for the preparation thereof
    Patent number: 5948395
    Abstract: An anhydrous cosmetic composition in the form of a soft paste, which comprises silicone materials, particularly a silicone gum, and a at least one wax. A process of preparation of such a material, involving mixing, heating, cooling, and kneading steps.
    Type: Grant
    Filed: May 1, 1998
    Date of Patent: September 7, 1999
    Assignee: L'Oreal
    Inventors: Veronique Le Bras-Roulier, Dolores Miguel-Colombel
  • Deodorant comprising metal oxide-carrying activated carbon
    Patent number: 5948398
    Abstract: A metal oxide-carrying activated carbon having an oxidation catalytic activity comprises a treated activated carbon obtained by carbonizing a carbon material, activating the obtained carbon with an activating gas comprising carbon dioxide and water vapor, said activating gas containing not more than 15% by volume of water vapor, and then cooling the activated carbon down to a temperature of not more than 300.degree. C. under the same atmosphere; and, carried thereon, 0.1 to 20% by weight as converted into metal of an oxide of at least one metal selected from the group consisting of iron, chromium, nickel, cobalt, manganese, zinc, copper, magnesium and calcium. A deodorant is obtained by adding 1 to 50 parts by weight of a plastic powder having an average particle diameter of 1 to 50 .mu.m to 100 parts by weight of the above metal oxide-carrying activated carbon. The above.
    Type: Grant
    Filed: September 14, 1994
    Date of Patent: September 7, 1999
    Assignee: Kuraray Chemical Co., Ltd.
    Inventors: Tetsuya Hanamoto, Yukihito Ohta, Eiji Tanaka, Hong Sang Eui, Park Young Min, Choi Yong Bok, Lee Chang Woo
  • Composition for inhibiting microbial adhesion on surfaces
    Patent number: 5942219
    Abstract: A composition for controlling deposition having a high flash point and being substantially free of volatile organic compounds is disclosed, the composition being a stable solution containing a dialkylsulfosuccinate, an ethylene oxide/propylene oxide block copolymer and a mineral acid.
    Type: Grant
    Filed: December 9, 1997
    Date of Patent: August 24, 1999
    Assignee: BetzDearborn Inc.
    Inventor: William A. Hendriks