Abstract: A method of reducing retro-repulsion of a stone during a laser lithotripsy procedure involves the use of a spacer tip or standoff sleeve to create a passage between the tip of a fiber and a stone, and to prevent collapse of a bubble formed by vaporization of and/or gas pressure on liquid present in the passage. The laser radiation may consist of continuous or quasi-continuous wave radiation that is relatively low in power compared to the therapeutic pulses, or may consist of the therapeutic pulses if the pulse frequency is high enough to prevent collapse of the bubble between pulses. The spacer tip or standoff sleeve further prevents collapse of the bubble and ingress of liquid into the laser path. The spacer tip or standoff sleeve may be a generally-cylindrical protective cap that is fitted to an end of the optical fiber and that extends beyond the fiber tip to provide a predetermined spacing or standoff between the fiber tip and the stone when the protective cap is in contact with the stone.

Abstract: A medical device is configured to deliver a series of electrical stimulation pulses including opposing polarity pulses. The medical device delivers a charge balancing pulse by modifying every nth pulse of the electrical stimulation pulses to reduce a net charge delivered over the series of electrical stimulation pulses. In some examples, the medical device may be an implantable medical device that is coupled to an extra-cardiovascular lead for delivering the cardiac pacing pulses.

Abstract: The invention, in one aspect, relates to an intravascular electrode system. The system comprises one or more electrodes supported on an elongated resiliently flexible support member, and the support member may be used to introduce the electrodes into a blood vessel. As the support member is introduced into the blood vessel the support member bends to follow the path of the blood vessel.

Abstract: A system including a medical device is provided. The medical device includes at least one sensor configured to acquire first data descriptive of a patient, first memory storing a plurality of templates, and at least one processor coupled to the at least one sensor and the first memory. The at least one processor is configured to identify a first template of the plurality of templates that is similar to the first data, to determine first difference data based on the first template and the first data, and to store the first difference data in association with the first template. The system may further include the programmable device.

Abstract: The present invention relates to an implantable cardiac device. The implantable cardiac device comprises a planar spiral for attaching the implantable cardiac device to a patient's tissue.

Abstract: An artificial intelligence self-learning-based static electrocardiography analysis method and apparatus, the method comprising data preprocessing, heartbeat detection, heartbeat classification based on a depth learning method, heartbeat verification, heartbeat waveform feature detection, measurement and analysis of electrocardiography events, and finally automatic output of reporting data, realizing an automated static electrocardiograph analysis method having a complete and rapid flow. The static electrocardiography analysis method can also record modification information of an automatic analysis result, collect modified data, and feed same back to the depth learning model to continue training, thereby continuously making improvements and improving the accuracy of the automatic analysis method.

Abstract: An electronic device is provided which can be worn on the body or implanted into the body, such as in the form of a pulse watch and/or a smartwatch and/or an implant. The electronic device includes a photoplethysmographic measuring device. A transmitter diode and a receiver diode are arranged under a window made of glass or glass ceramics. The window is implemented as a compression glass seal and/or as a fiber-optic plate.

Abstract: A system for use with a neurostimulator coupled to one or more electrodes implanted adjacent neural tissue of a patient. The system comprises a user input device configured for allowing a user to select different nerve fiber diameters and to select a set of stimulation parameters. The system further comprises processing circuitry configured estimating regions of activation within the neural tissue of the patient based on the selected nerve fiber diameters and the selected stimulation parameter set. The system further comprises a display device configured for displaying the estimated regions of tissue activation. The user input device may further be configured for allowing the user to select different tissue regions of therapy, in which case, the display device may display the different tissue region on a human body map, and different indicia associating the displayed tissue regions for therapy to displayed estimated regions of tissue activation.

Abstract: Systems, methods, devices, and techniques for analyzing and applying features of a T-wave derived from an electrocardiogram. A computing system can receive a set of data that characterizes an electrocardiogram of a patient. The system can analyze the set of data to identify a T-wave that occurs in the electrocardiogram. The system can determine values of one or more features of the T-wave and provide the information that identifies the values of the one or more features of the T-wave to a user.

Abstract: Computer implemented methods and systems are provided for automatically determining capture thresholds for an implantable medical device equipped for cardiac stimulus pacing using a multi-pole left ventricular (LV) lead. The methods and systems measures a base capture threshold for a base pacing vector utilizing stimulation pulses varied over at least a portion of an outer test range. The base pacing vector is defined by a first LV electrode provided on the LV lead and a second electrode located remote from an LV chamber. The methods and systems designate a secondary pacing vector that includes the first LV electrode and a neighbor LV electrode provided on the LV lead. The methods and systems further define an inner test range having secondary limits based on the base capture threshold, wherein at least one of the limits for the inner test range differs from a corresponding limit for the outer test range.

Abstract: In some examples, a tether head assembly of a delivery system includes an inner retainer and an outer retainer that defines an aperture comprising a receptacle configured to receive an attachment member of a medical device, a passageway, and a groove. The inner retainer is movable within the groove between a second position in which the passageway is dimensioned to receive the attachment member and a first position in which the passageway is dimensioned to prevent passage of the attachment member. In some examples, a tether handle assembly defines a channel, a force transmitter within the channel, a slidable member partially received within a first end of the channel and a button partially received within a second end of the channel. Distally-directed force applied to the button may cause the force transmitter to apply proximally-directed force to the slidable member, moving the slidable member and an attached pull wire proximally.

Abstract: The neural interface system of the preferred embodiments includes an electrode array having a plurality of electrode sites and a carrier that supports the electrode array. The electrode array is coupled to the carrier such that the electrode sites are arranged both circumferentially around the carrier and axially along the carrier. A group of the electrode sites may be simultaneously activated to create an activation pattern. The system of the preferred embodiment is preferably designed for deep brain stimulation, and, more specifically, for deep brain stimulation with fine electrode site positioning, selectivity, tunability, and precise activation patterning. The system of the preferred embodiments, however, may be alternatively used in any suitable environment (such as the spinal cord, peripheral nerve, muscle, or any other suitable anatomical location) and for any suitable reason.

Abstract: A first sensing element including an accelerometer-based sensor for sleep disordered breathing (SDB) care.

Abstract: A method, system, and device for electroporation. A system may include a medical device with a plurality of electrodes borne on an expandable element and an energy generator in communication with the electrodes. The energy generator may have processing circuitry configured to selectively deliver electroporation energy to at least one of the electrodes. The processing circuitry may determine whether an alert condition is present and, if so, cease the delivery of electroporation energy to one or more electrodes identified as the cause of the alert condition and/or prevent the delivery of electroporation energy to the one or more electrodes identified as the cause of the alert condition. The energy generator may also be configured to deliver electroporation energy in a sequence of a plurality of energy delivery patterns to enhance lesion formation.

Abstract: Described herein are systems and methods for collecting physiological information from a user and determining information including, but not limited to, a user's heart rate, blood pressure, oxygen levels (SvO2), hydration, respiration rate, and heart rate variability. Physiological information is collected from one or more modules, each comprising a sensor array. The sensor array(s) can comprise, among other things, light sources, photo detectors, ECG electrodes/sensors, bio impedance sensors, galvanic skin response sensors, tonometry/contact sensors, accelerometers, pressure sensors, acoustic sensors, and electromagnetic sensors. The information collected from a user can be used to cross-reference a database comprising similar information for a number of subjects as well as verified measurements for each subject including, but not limited to, blood pressure, oxygen levels (SvO2), hydration, respiration rate, and heart rate variability.

Abstract: A blood pump having a housing including an inlet element. The inlet element has a proximal portion sized to be received within at least a portion of a heart of a patient and defines a major longitudinal axis. A rotor is configured to rotate within the housing about the major longitudinal axis and impel blood from heart. At least one stator is disposed within the housing and positioned within the housing at least one from the group consisting of upstream and downstream from the rotor. During operation of the blood pump the rotor is maintained at an oblique angle with respect to the major longitudinal axis.

Abstract: In some examples, a device includes processing circuitry configured to determine a set of correlation coefficient values for first and second physiological parameters. The processing circuitry is further configured to determine a metric of the correlation coefficient values for a first plurality of bins and for a second plurality of bins, wherein each bin of the first plurality has a first bin parameter and each bin of the second plurality of bins has a second bin parameter different than the first bin parameter. The processing circuitry is also configured to determine a composite estimate of a limit of autoregulation of the patient based on the metric for the first plurality of bins and the metric for the second plurality of bins. The processing circuitry is configured to determine an autoregulation status based on the composite estimate and output, for display via the display, an indication of the autoregulation status.

Abstract: An Electrocardiography (ECG) noise-filtering device is provided in the invention. The ECG device includes a filter and a calculation circuit. The filter receives a first ECG signal and performs a Savitzky-Golay algorithm to generate a second ECG signal. The calculation circuit is coupled to the filter to receive the second ECG signal and processes the second ECG signal according to a Stationary Wavelet Transform (SWT) algorithm to generate a noise signal, and subtracts the noise signal from the second ECG signal to filter the noise signal in the first ECG signal.

Abstract: An apparatus for measuring an electrocardiogram includes a signal detector, a signal converter, and a processor. The apparatus detects a particular component from an electrocardiogram digital signal and generates measurement data for an electrocardiogram digital signal by applying different conversion gains to an interval including the particular component and a remaining interval.

Abstract: A long-range wireless charging enhancement structure for implantable medical devices (IMDs) is disclosed. The abovementioned enhancement structure provides a possibility for long-range charging the IMDs, which maintains the quality of user's lives and also reduces the risks of replacing the batteries through surgeries. The enhancement structure includes an enhancer, which comprises an emitter, a carrier, an IMD, and an enhancement module. The enhancement module is set within the carrier and disposed at the outer surface of user's skin between the emitter and the IMD. The charging signals emitted by the emitter is enhanced by the enhancement module and further transmitted for charging the IMD inside the user's tissue.