Patents Examined by Rosalynd Keys
  • Patent number: 11053185
    Abstract: The disclosure discloses a dendritic polyethylene glycol derivative and a preparation method and an application thereof. The dendritic polyethylene glycol derivative has a structure of formula (I), has multiple end functional groups, has a stronger water solubility in comparison with linear-chain polyethylene glycol, and can solve a problem of insufficient water solubility due to the increase of load when modifying an insoluble drug by the polyethylene glycol. The preparation method of the dendritic polyethylene glycol derivative provided by the disclosure has mild reaction conditions, is green and environmentally friendly, is low in cost, and is easy to implement industrialization.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: July 6, 2021
    Assignee: JENKEM TECHNOLOGY CO., LTD. (TIANJIN)
    Inventors: Hui Zhu, Meina Lin, Xuan Zhao
  • Patent number: 11014878
    Abstract: The present invention relates to a method for preparing 3-methylthiopropionaldehyde by reacting methyl mercaptan with acrolein, in which deviations in the stoichiometry of methyl mercaptan to acrolein in the reaction to give 3-methylthiopropionaldehyde are compensated for by supplying or by forming 1,3-bis(methylthio)-1-propanol, and also to the use of 1,3-bis(methylthio)-1-propanol as a storage form of methyl mercaptan and/or 3-methylthiopropionaldehyde.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: May 25, 2021
    Assignee: Evonik Operations GmbH
    Inventors: Stephan Rautenberg, Sascha Ceylan, Martin Koerfer, Judith Hierold, Harald Jakob, Christian Kaiser, Rainer Malzkorn, Thorsten Merker, Anja Nordschild
  • Patent number: 11008285
    Abstract: The present disclosure relates to a process for synthesis of mesotrione. The process comprises reacting 4-toluene sulfonyl chloride with alkali metal sulphite and alkali metal bicarbonate to obtain alkali metal toluene-4-sulfinate. The alkali metal toluene-4-sulfinate is reacted with alkali metal salt of monochloroacetic acid to obtain 4-methylsulfonyl toluene. Further, 4-methylsulfonyl toluene is nitrated to obtain 2-nitro-4-methylsulfonyl toluene. 2-nitro-4-methylsulfonyl toluene is oxidized and then halogenated to obtain 2-nitro-4-methylsulfonylbenzoyl halide. 2-nitro-4-methylsulfonylbenzoyl halide is reacted with alkali metal salt of 1,3-cyclohexanedione to obtain 3-(2-Nitro-4-methylsulfonylbenzoyloxy)cyclohexen-1-one which is reacted with base, a third fluid medium and cyanide ion source to obtain an amorphous mesotrione. The present disclosure also discloses the steps of converting the amorphous mesotrione to crystalline mesotrione having purity greater than 99%.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: May 18, 2021
    Assignee: GHARDA CHEMICALS LIMITED
    Inventors: Keki Hormusji Gharda, Suchet Saran Mathur, Nandkumar Janardan Jain, Shekhar Vishwanath Sathe, Pragnesh Dalpatram Damania
  • Patent number: 10968154
    Abstract: Disclosed is a method of: providing a fiber having propylene oxide adsorbed thereon; exposing the fiber to a gaseous sample; allowing the propylene oxide to react with any chlorine in the sample to form chloro-2-propanol. The method can be used to detect potassium chlorate.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: April 6, 2021
    Assignee: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Lauryn E. DeGreeff, Janet M. Crespo Cajigas
  • Patent number: 10954185
    Abstract: The invention discloses a process for hydrogenation (alkenes, carbonyl compounds and aromatics) and hydrodeoxygenation (methoxy phenols) of organic molecules using hydrous ruthenium oxide (HRO) and its supported form as a recyclable heterogeneous catalyst in aqueous medium with good yield of desired products (70-100%) under mild reaction conditions.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: March 23, 2021
    Assignee: Council of Scientific & Industrial Research
    Inventors: Kannan Srinivasan, Sreedhar Gundekari
  • Patent number: 10947174
    Abstract: A method for preparing trimethylolpropane, the method including: subjecting dimethylolbutanal (DMB) to a hydrogenation reaction in the presence of a metal catalyst and an alcohol solvent. During the hydrogenation reaction, a weight ratio of the alcohol solvent based to dimethylolbutanal is 2 to 10.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: March 16, 2021
    Assignee: LG CHEM, LTD.
    Inventors: Dawon Jung, Sungshik Eom, Tae Yun Kim, Dong Hyun Ko, Mi Young Kim, Min Ji Choi, Taewoo Kim
  • Patent number: 10941092
    Abstract: The present invention relates to a two-stage hydroformylation process for producing pound of the formula (I) and to a process for producing a compound of the formula (V) comprising the two-stage hydroformylation process for producing a compound of the formula (I) followed by hydrogenation of the compound of the formula (I).
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: March 9, 2021
    Inventors: Marek Pazicky, Martin Ernst, Nicolas Marion, Rocco Paciello, Johann-Peter Melder, Hermann Luyken
  • Patent number: 10927074
    Abstract: The present invention discloses processes for producing methyl ethyl sulfide by contacting dimethyl sulfide and diethyl sulfide in the presence of a suitable catalyst. Methyl ethyl sulfide can be used as an odorant in natural gas. Integrated mercaptan and sulfide manufacturing systems and integrated methods for making mercaptans and sulfides also are disclosed.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: February 23, 2021
    Inventors: Daniel M. Hasenberg, Kenneth M. Lassen, Jason L. Kreider, Henry Hwu
  • Patent number: 10906861
    Abstract: Described are methods of making organic compounds by metathesis chemistry. The methods of the invention are particularly useful for making industrially-important organic compounds beginning with starting compositions derived from renewable feedstocks, such as natural oils. The methods make use of a cross-metathesis step with an olefin compound to produce functionalized alkene intermediates having a pre-determined double bond position. Once isolated, the functionalized alkene intermediate can be self-metathesized or cross-metathesized (e.g., with a second functionalized alkene) to produce the desired organic compound or a precursor thereto. The method may be used to make bifunctional organic compounds, such as diacids, diesters, dicarboxylate salts, acid/esters, acid/amines, acid/alcohols, acid/aldehydes, acid/ketones, acid/halides, acid/nitriles, ester/amines, ester/alcohols, ester/aldehydes, ester/ketones, ester/halides, ester/nitriles, and the like.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: February 2, 2021
    Assignee: Wilmar Trading Pte Ltd
    Inventors: Timothy W. Abraham, Hiroki Kaido, Choon Woo Lee, Richard L. Pederson, Yann Schrodi, Michael John Tupy
  • Patent number: 10894756
    Abstract: The invention discloses a method for catalytically hydrogenating oxalates. In the method, an oxalate and hydrogen gas are contacted with a nanotube assembled hollow sphere catalyst, to produce a product comprising glycolate or glycol. The predominant chemical components of the catalyst include copper and silica, in which the copper is in an amount of 5 to 60% by weight of the catalyst, and the silica is in an amount of 40-95% by weight of the catalyst. The catalyst has a specific surface area of 450-500 m2/g, an average pore volume of 0.5-1 cm3/g, and an average pore diameter of 5-6 nm. The catalyst is in a structure of assembling nanotubes on hollow spheres, wherein the hollow spheres have a diameter of 50-450 nm, and a wall thickness of 10-20 nm, and the nanotubes, vertically arranged on the surfaces of the hollow spheres, have a diameter of 3-5 nm, and a length of 40-300 nm.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: January 19, 2021
    Assignee: Tianjin University
    Inventors: Xinbin Ma, Yue Wang, Dawei Yao, Jing Lv, Yujun Zhao, Shengping Wang
  • Patent number: 10882806
    Abstract: The present invention provides a process for preparing 4-methyl-5-nonanone of the following formula (3), the process comprising at least a step of subjecting pentanoic anhydride of the following formula (1) and a 2-pentyl nucleophilic reagent of the following general formula (2), in which M represents Li, MgZ1, or ZnZ1, wherein Z1 represents a halogen atom or a 2-pentyl group, to a nucleophilic substitution reaction to produce 4-methyl-5-nonanone (3), as well as a process for preparing 4-methyl-5-nonanol of the following formula (7), the process comprising at least steps of preparing 4-methyl-5-nonanone and subjecting the obtained 4-methyl-5-nonanone and a reducing agent to a reduction reaction to produce 4-methyl-5-nonanol (7).
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: January 5, 2021
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Yuki Miyake, Takeshi Kinsho, Ryo Komatsu
  • Patent number: 10882809
    Abstract: A halogenated ?-fluoroether of the formula (2) (where HaloR represents haloalkyl; R1 represents hydrogen, halogen, alkyl or substituted alkyl; and R2 represents alkyl or substituted alkyl) is produced efficiently on an industrial scale by reacting a halogenated aldehyde of the formula (1) (where HaloR represents haloalkyl) or an equivalent thereof with hydrogen fluoride.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: January 5, 2021
    Assignee: Central Glass Company, Limited
    Inventors: Kenji Hosoi, Naoya Ueshima
  • Patent number: 10882810
    Abstract: The present invention relates to a process for the preparation of the compounds of formula II using a lanthanoid salt.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: January 5, 2021
    Assignee: BASF AGRO B.V.
    Inventors: Joachim Gebhardt, Jan Klaas Lohmann, David Anderson, Michael Rack, Roland Goetz
  • Patent number: 10882805
    Abstract: The present invention provides a process for preparing 4-methyl-5-nonanone of the following formula (3): the process comprising at least a step of subjecting 2-methylpentanoic anhydride of the following formula (1) and an n-butyl nucleophilic reagent of the following general formula (2) in which M represents Li, MgZ1, or ZnZ1, wherein Z1 represents a halogen atom or an n-butyl group, to a nucleophilic substitution. reaction Coproduce 4-methyl-5-nonanone (3), as well as a process for preparing 4-methyl-5-nonanol of the following formula (5), the process comprising at least steps of preparing 4-methyl-5-nonanone; and subjecting the obtained 4-methyl-5-nonanone and a reducing agent to a reduction reaction to produce 4-methyl-5-nonanol (5).
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: January 5, 2021
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Yuki Miyake, Takeshi Kinsho, Yusuke Nagae
  • Patent number: 10874983
    Abstract: There is proposed an efficient recovery of methanol from waste gases loaded with methanol in an integrated flow chart for the production and processing of methanol. The methanol fractions separated from the waste gases are recovered within the already existing, distillative processing of the crude methanol to pure methanol, so that no separate apparatuses are required for the recovery of the methanol from the loaded scrubber waste waters. The valuable substance methanol is recovered and the impact on the environment is reduced. By means of particular aspects of the invention the need for water as washing agent can be reduced further.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: December 29, 2020
    Assignee: L'Air Liquide Societe Anonyme Pour L'Etude Et L'Exploitation Des Procedes Georges Claude
    Inventors: Karin Huder, Veronika Gronemann, Tobias Oelmann
  • Patent number: 10870620
    Abstract: The present disclosure provides a radioactive carbon-14 labeled XCLSBM in the structure of Formula 4 and its preparation method and applications. A 14C labeled raw material is used to synthesize a 14C-labeled XCLSBM, and a method for synthesizing a trace 14C-labeled marker of 14C-labeled XCLSBM is established, which avoids high-temperature, high-pressure reactions and the production process is safe with a low synthesis cost. The radioactive carbon-14 labeled XCLSBM can be used to trace the migration and transformation, metabolic degradation, absorption and enrichment of XCLSBM in environment and living bodies, for providing technical supports for comprehensive evaluation of the ecological safety of XCLSBM.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: December 22, 2020
    Assignee: Zhejiang University
    Inventors: Wang Haiyan, Lu Yuhui, Ye Qingfu
  • Patent number: 10851036
    Abstract: Systems and methods are provided for direct methane conversion to methanol. The methods can include exposing methane to an oxidant, such as O2, in a solvent at conditions that are substantially supercritical for the solvent while having a temperature of about 310° C. or less, or about 300° C. or less, or about 290° C. or less. The solvent can correspond to an electron donor solvent that, when in a supercritical state, can complex with O2. By forming a complex with the O2, the supercritical electron donor solvent can facilitate conversion of methane to methanol at short residence times while reducing or minimizing further oxidation of the methanol to other products.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: December 1, 2020
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Partha Nandi, Steven L. Suib, Sumathy Raman
  • Patent number: 10836715
    Abstract: A process for preparing polyaryl ethers in which a polycondensation of the monomer building blocks is carried out using microwave irradiation leads to thermoplastic molding compositions having improved color properties.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: November 17, 2020
    Assignee: BASF SE
    Inventors: Frauke Thrun, Joaquim Henrique Teles, Jun Gao
  • Patent number: 10836696
    Abstract: The present invention provides a method for increasing the UV transmittance of ethylene glycol. The method uses an ethylene glycol solution and hydrogen as raw materials, and uses an alloy catalyst comprising nickel, one or more rare-earth elements, tin, and aluminum, the contents thereof in parts by weight being 10-90, 1-5, 1-60, and 5-9, respectively. The method of the present invention uses an inexpensive, stable-in-aqueous-phase, carrier-free alloy as a catalyst, and continuously adds hydrogen to reduce unsaturated impurities in ethylene glycol. In application of the method of the present invention in continuous industrial-scale production, the use of this type of alloy catalyst could be especially significant for the achievement of long-term system stability and control of production costs.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: November 17, 2020
    Assignees: The Coca-Cola Company, Changchun Meihe Science and Technology Development Co., Ltd.
    Inventors: Yi Yuan, Haiyu Ren
  • Patent number: 10815178
    Abstract: The present invention relates to a method of preparing ortho substituted phenols from 2,5-dimethylfuran and propargyl ethers in the presence of a gold(I) complex. It is particularly advantageous to use 2,5-dimethylfuran as this offers an ecological beneficial synthesis of said ortho substituted phenols.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: October 27, 2020
    Assignee: DSM IP ASSETS B.V.
    Inventors: Ulla Letinois, Stephan Ackermann, Jonathan Alan Medlock, Hajo Lehmann