Abstract: Certain embodiments of the invention are directed to evaluating and identifying cells by recording and interpreting a time-dependent signal produced by unique cell respiration and permeability attributes of isolated viable cells.
Abstract: A taste and flavor profile modifying composition is described. The composition includes a blend of glucosylated steviol glycosides and residual steviol glycosides which can modify the intensity of a taste and/or flavor in a food or beverage product.
Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating muscle diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
Abstract: The present technology generally relates to a method for modulating in situ production of energy by a biological tissue. The method comprises stimulating the biological tissue by exposing the biological tissue to a photostimulated biophotonic composition for a time sufficient to initiate the production of energy by the biological tissue.
Type:
Grant
Filed:
February 8, 2018
Date of Patent:
April 9, 2024
Assignee:
FLE INTERNATIONAL S.R.L.
Inventors:
Nikolaos Loupis, Remigio Piergallini, David Ohayon, Lise Hébert, Giovanni Scapagnini
Abstract: A method of determining the feed efficiency and methane production of a ruminating animal comprising analyzing the number and/or diversity of a bacterial taxon of a microbiome of the animal or of a gene content of said microbiome, wherein a number and/or diversity of said taxon below a predetermined level is indicative of an animal having a high feed efficiency and low methane production, or a number of genes below a predetermined level is indicative of an animal having a high feed efficiency and low methane production.
Type:
Grant
Filed:
February 9, 2021
Date of Patent:
March 26, 2024
Assignee:
The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center)
Abstract: Described herein are methods and compositions for using microbial agents (probiotics) and agents that promote growth of certain microbes (prebiotics) for management (including prevention and treatment) of musculoskeletal disorders, including osteoporosis, osteopenia, Paget's disease, stunting, osteoarthritis, osteomyelitis, and delayed or non-union fractures. Also described herein are methods and compositions for using probiotics and prebiotics for management of inflammation, and symptoms of menopause.
Type:
Grant
Filed:
March 9, 2023
Date of Patent:
March 26, 2024
Assignee:
Solarea Bio, Inc.
Inventors:
Eric Michael Schott, Maria Juliana Soto-Giron, Gerardo V. Toledo
Abstract: In order to make available the health-promoting and healing properties of curcumin to the human or animal organism, also in combination with at least one further active substance, a solubilizate consists of or contains a content of curcumin equal to or smaller than 10 wt %, preferably equal to or smaller than 7.5 wt %, most preferably 6 wt %, and at least one emulsifier with an HLB value in a range below 18, preferably between 13 and 18, namely polysorbate 80 or polysorbate 20 or a mixture of polysorbate 20 and polysorbate 80, with an average diameter of the curcumin-loaded micelles ranging from 5 nm to 40 nm, preferably from 6 nm to 20 nm, most preferably from 7 nm to 10 nm, for use in particular as a dietary supplement and/or pharmaceutical drug for treating and/or preventing diseases involving inflammation, cancer and other diseases.
Abstract: Provided is an “all natural” biologic-enhancing beverage (BioBeverage), which contains, in addition to purified water, electrolytes, vitamins, anti-oxidants, micronutrients, natural fruit infusion, natural sweetener, Citicoline, to enhance brain/neurologic function, neurologic maintenance, repair and regeneration, CoQ10, to enhance cardiovascular energy and health, Hydroxyproline, to enhance connective tissue maintenance, repair and regeneration, and a niacinamide adenine dinucleotide (NAD+) precursor to promote overall health, including neurologic, cardiovascular and connective tissues maintenance and repair, and if present, reduce risks and symptoms of multiple neurodegenerative disorders by maintenance of healthy mitochondrial function.
Type:
Grant
Filed:
April 29, 2021
Date of Patent:
March 19, 2024
Assignee:
HEH RESEARCH & DEVELOPMENT SERVICE, INC.
Abstract: A stable pharmaceutical formulation or suspension has a pharmaceutical active agent, agave, and a dilutant. The formulation or suspension has viscosity suitable for drinking.
Abstract: Herbal composition having an effect of reducing uric acid, which is made from the following herbal materials in specified portions by weight: 4-30 portions of Glabrous greenbrier rhizome, 2-15 portions of Chicory, 2-15 portions of Herba Plantaginis, 2-20 portions of Coix seed, and 2-10 portions of Kudzuvine Root. The composition may be used in combination with modern Western medicines to achieve optimal effects.
Type:
Grant
Filed:
December 30, 2013
Date of Patent:
March 12, 2024
Assignee:
INFINITUS (CHINA) COMPANY LTD.
Inventors:
Xiaofei Xu, Xiaolei Guo, Chungwah Ma, Bin Shi, Zhen Luo
Abstract: The claimed invention provides therapeutic as well as protective measures against colorectal cancer by utilizing genetically modified gut bacteria (101) in conjunction with an optimized diet high in cruciferous vegetable intake. According to the claimed system and method, engineered gut bacteria maximize the therapeutic value of the cruciferous vegetable diet to eradicate, offset or prophylactically prevent the onset of colorectal cancer. In the claimed invention gut bacteria Escherichia coli bind specifically to the heparan sulphate proteoglycan on colorectal cancer cells to secrete the enzyme myrosinase to transform host-ingested glucosinolates which are natural components of cruciferous vegetables to sulphoraphane, an organic small molecule with known anti-cancer activity.
Abstract: A multi-component regimen for the treatment of a skin condition including administering at least two components of at least one galenic microbial composition, applying at least one acidic composition, applying at least one mineral salt composition, illuminating an area of the skin and heating an area of the skin. The regimen includes at least one of administering at least one galenic microbial composition and illuminating an area of the skin. Also provided is a galenic microbial composition including bacteria of the phylum Actinobacterium and a dermatologically compatible carrier. Further provided is a wearable cutaneous-treatment device for the therapeutic illumination of mammalian skin when activated, to project light outwards from h inner surface to illuminate at least a portion the area of skin.
Abstract: Provided herein are, inter alia, compositions, systems, and methods for preventing or treating acne. Included are compositions, combinations, systems, and methods comprising at least one Propionibacterium acnes bacteriophage, at least one anti-acne compound, and a pharmaceutically acceptable carrier. Also included are compositions, combinations, and systems comprising a Propionibacterium acnes bacteriophage and an enzyme. Methods for preventing or treating acne are also provided.
Abstract: A composition and method for ameliorating drug-seeking behavior in drug addicts who have stopped using the addicted-to drug and who have reestablished non-addict physiological chemical balance.
Abstract: Provided herein are compositions and methods for the inhibition of enteric infection. In particular, compositions comprising bacteria of the class Clostridia are administered to human and/or animal subjects to prevent or decrease susceptibility to enteric infection.
Type:
Grant
Filed:
July 15, 2022
Date of Patent:
January 30, 2024
Assignee:
The University of Chicago
Inventors:
Cathyrn R. Nagler, Gabriel Nunez, Yun-Gi Kim
Abstract: The present invention relates to a built-in bio-sleeve and preparation method and use thereof. In order to provide a suitable built-in bio-sleeve material for dorsal nerve isolation surgery and penis enlargement surgery, a novel acellular allogeneic dermal matrix material is prepared in the present invention, which is manufactured into a built-in bio-sleeve for the treatment of premature ejaculation and short and small penis. The acellular allogeneic dermal matrix or the built-in bio-sleeve of the present invention is used for dorsal nerve isolation surgery, penis enlargement or lengthening surgery without cutting off the dorsal nerve, thereby avoiding the probability of psychological erectile dysfunction caused by the patient's worry about cutting off the dorsal nerve.
Abstract: The present invention provides improved methods, facilities and systems for parallel processing of biological cellular samples in an efficient and scalable manner. The invention enables parallel processing of biological cellular samples, such as patient samples, in a space and time efficient fashion. The methods, facilities and systems of the invention find particular utility in processing patient samples for use in cell therapy.
Abstract: The present invention relates to a method for producing marine algae-derived agarotriose, and a use thereof as a prebiotic. More specifically, the present invention investigates the characteristics of agarotriose as a prebiotic which is selectively metabolized by probiotic microorganisms, thereby enabling agarotriose to be used as an anti-cancer or anti-inflammatory agent in the fields of food and pharmaceuticals, and enabling agarotriose to be obtained at high yield through efficient purification with minimal loss after enzymatic hydrolysis of a red algae-derived polysaccharide without pre-treatment.
Type:
Grant
Filed:
April 19, 2022
Date of Patent:
January 16, 2024
Assignee:
Korea University Research and Business Foundation
Inventors:
Kyoung Heon Kim, Yong-Su Jin, Eun-Ju Yun, Dong-Hyun Kim, Sora Yu, Kyung-Mun Cho, Na Jeong Park
Abstract: Compositions and methods are provided in which a nutritional supplement that is utilized in the treatment viral infections (e.g., coronavirus, HCV, HIV), by correcting dysregulation of apoptosis, reducing production of pro-inflamatory cytokines, and increasing production of host anti-viral compounds. The nutritional supplements can be used in combination with known antiviral therapies, as well as low level radiotherapy and/or chemotherapy drugs conventionally used in the treatment of neoplastic disease.