Abstract: A composition and a kit comprising a nitrite source admixed with a gelling agent for nitric oxide production. Also disclosed is a method for generating nitric oxide, which finds applications in the treatment of various diseases.

Abstract: A method of treating skin with a composition is disclosed. The method can include topically applying an effective amount of a composition to skin in need thereof, wherein the composition comprises an aqueous extract of plankton comprising an exopolysacchride synthesized by Vibo alginolyticus, an aqueous extract of Phragmites communis, an aqueous extract of Poria cocos, and an aqueous extract of Cucurbita pepo (pumpkin) seed.

Abstract: The present invention relates to an organoleptically improved dietary fiber composition comprising Trigonella foenum-graecum (fenugreek) seeds in the form of flakes with improved palatability, and method(s) of preparing the said composition. More particularly, invention relates to nutrient rich de-bitterised and de-fatted fenugreek dietary fiber and administering the same in a subject to bring satiety, feeling of fullness, appetite suppression, less desire to consume food, which may further lead to reduction or management of weight. The present invention can be used for the development of functional food, dietary plan and as a nutritional supplement. The present invention also relates to methods of managing various conditions such as, but not limited to, management of weight, appetite scores, glucose homeostasis, body mass index and serum insulin levels or any combinations thereof using the said composition.

Abstract: The present invention relates to a maca extract and uses thereof. The part of the maca extract extracted with polar solvent has anti-thrombotic activity, the part of the maca extract extracted with medium and low polarity solvents has anti-neutrophilic inflammatory and anti-allergic activities, the part of the maca extract extracted with low polarity solvent has anti-neutrophilic inflammatory activity and has pro-angiogenic activity.

Abstract: In an embodiment, a nutritional supplement composition is provided. The nutritional supplement composition is provided including a fish extract derived from fish collagen dipeptide, corn powder from from the Zea mays l. strain and raspberry extract of the Rubus idaeus strain. The nutritional supplement is in the form of a compound known as DERMAGRANT™.

Abstract: The present invention provides a health functional food composition for promoting height growth comprising a Humulus japonicus extract or a Humulus japonicus crushed product as an active ingredient and a composition for promoting height growth comprising a watermelon/garlic concentrate in addition to a Humulus japonicus extract or a Humulus japonicus crushed product.

Abstract: Disclosed is a method for improving eye conditions comprising orally administering to humans, an ethanol-soluble component-containing degradation product obtained by degrading a comb with a protease and removing a solid.

Abstract: An apparatus for applying a portion of a plant product to the epidermis of a human, the apparatus adapted to be removably fastened with a belt or strap to a human body, comprising: the belt or strap; at least one pocket or container adapted to removably receive the portion of the plant product, the at least one pocket or container comprising: a contact portion that contacts the human body, when the apparatus is removably fastened to the human body, an opposing portion, opposing the contact portion, the opposing portion adapted to allow the portion of the plant product to be removably inserted into the at least one pocket or container, the contact portion having a plurality of holes, the plurality of holes allowing the portion of the plant product to contact the epidermis, when the plant product is removably inserted into the at least one pocket or container.

Abstract: The present application is directed to composition comprising various maca extracts and the use of such compositions for treating certain diseases, disorders, and conditions.

Abstract: Provided herein are formulations composed of fish roe wax extract and Nigella sativa oil extract. This oily composition is prepared and used as a treatment for addiction withdrawal symptoms by regulating dopamine and serotonin unbalance in a subject in need thereof. The prepared formulation alleviated the addiction effect of cocaine after daily single dosing of addiction-induced mice.

Abstract: The present invention relates to a process for producing an extract derived from sugar cane, the process comprising: i) mixing a sugar cane derived product with ethanol to produce an extraction mixture comprising at least about 50% v/v ethanol; ii) allowing a precipitate to form in the extraction mixture; iii) removing the precipitate from the extraction mixture to obtain a supernatant; and iv) removing ethanol from the supernatant to produce the extract derived from sugar cane. The present invention further relates to extracts produced according to the process of the invention. The invention also relates to the use of such extracts in a method of lowering the available calorific value of a food or beverage, in treating or preventing disease, and as a nutritional supplement, dietary supplement, sports nutrition product, food coating or pharmaceutical product.

Abstract: The present invention relates to the fields of medicine, cell biology, molecular biology and genetics. In particular, the present invention provides methods to isolate and purify microvesicles from cell culture supernatants and biological fluids. The present invention also provides pharmaceutical compositions of microvesicles to promote or enhance wound healing, stimulate tissue regeneration, remodel scarred tissue, modulate immune reactions, alter neoplastic cell growth and/or mobility, or alter normal cell growth and/or mobility. The present invention also provides compositions of microvesicles to be used as diagnostic reagents, and methods to prepare the compositions of microvesicles.

Abstract: The present invention may provide a pharmaceutical composition for preventing or treating skin diseases, a cosmetic composition for preventing or improving skin diseases, and a stem cell therapeutic agent, which comprise an induced pluripotent stem cell-derived mesenchymal stem cell (iMSC), a culture thereof, or an exosome isolated from an iMSC or iMSC culture as active ingredients. When the composition of the present invention, etc. is used, it is possible to provide a composition for improving, preventing or treating skin diseases and a stem cell therapeutic agent which have an improved immunomodulating function over conventional mesenchymal stem cells.

Abstract: Nutritional supplements and methods of nutritional supplementation affecting the endocannabinoid system are provided. These nutritional supplements and methods of nutritional supplementation support the endocannabinoid systems of subjects by providing a blend of hemp oil, black pepper oil, black cumin seed oil, and white frankincense oil to prime ECS receptors and activate them to provide improvements to the ECS in a subject, affecting their pain response, mood, stress response, and sleep.

Abstract: The present invention includes composition and methods for treating inflammation and/or pain, the composition comprising: hemp cannabidiol (cannabinoid) 0.1%-0.6% weight percent; menthol 3.0-4.0% weight percent; arnica montana 0.1-5.0% weight percent; camphor 0.1-5.0% weight percent; bosweila serrata extract 0.1-5.0% weight percent; camphor terpene 0.1-5.0% weight percent; isopropyl alcohol <30% weight percent; glycerin <6.0% weight percent; and qs with water.

Abstract: A method of treating or alleviating symptoms of a disorder or a condition in a subject, including identifying the disorder or the condition of a subject, the disorder or condition identified based on first measures of a bloodstream concentration of a substance or a blood stream count of cellular elements, orally administering to said subject an amount of cannabidiol over a period of time effective treat or alleviate symptoms of said disorder or said condition, altering the bloodstream concentration of said substance or said blood stream count of cellular elements, and assessing efficacy of treating or alleviating symptoms of the disorder or the condition evidenced by comparing second measures of the bloodstream concentration of the substance or the blood stream count of cellular elements after the period time to the first measures of bloodstream concentration of the substance or the blood stream count of cellular elements.

Abstract: The invention concerns novel compositions, comprises at least 2 different sources of ?-3 fatty acids, wherein the first is hoki roe powder at 5% (w/w) particularly for use in supplements and/or animal or human food stuffs. The invention may further relate to the treatment of veterinary conditions, such as use in the improvement of inflammation or joint related disorders that maybe associated with inflammation.

Abstract: The present invention relates to a pharmaceutical composition for preventing and treating cell proliferative diseases comprising a feather of birds and a scale of fish, a scale transformed from the dermis, a degenerated or cornified variant of a scale, or a scale or horny scale of reptiles as an active ingredient. More particularly, the present invention relates to a pharmaceutical composition for preventing and treating cell proliferative diseases comprising a mixture of 70˜85 weight % of a feather of birds and 15˜30 weight % of a scale of fish, a scale transformed from the dermis, a degenerated or cornified variant of a scale, or a scale or horny scale of reptiles as an active ingredient. The inventive composition has the effect of inhibiting and preventing growth of cancer cells. Accordingly, the inventive composition may be used for anticancer purposes to prevent, ameliorate or treat cancer.

Abstract: A compound and methods are provided for treating, preventing or ameliorating infertility or reduced fertility in an individual, wherein said compound is capable of regulating the activity of Nuclear Factor, Erythroid 2 Like 2 (NFE2L2).

Abstract: The present specification discloses a composition for external application to skin, containing a tea plant root extract as an active ingredient, for treatment of skin damage caused by fine dust, whereby the expression level of one or more selected from a group consisting of IL-36G (NM_019618), S100A7 (NM_002963), S100A8 (NM_002964) and XDH (NM_000379), which are genes in skin cells the expression level of which is affected by fine dust, is regulated to a normal level.