Abstract: Provided are liquid and powder grape extracts having elevated phenolic content. The extracts can be made from grape seeds, grape skins, or a combination thereof. In some instances, extracts may be blends of grape seed extracts and grape skin extracts. Methods of manufacturing such extracts area also provided. Such methods involve controlled temperature conditions to increase yield of phenolic compounds in the extracts. Methods of using the extraction for treating subjects are also provided, including treatment of cancer and end-organ damage relating to hypertension.
Type:
Grant
Filed:
April 3, 2017
Date of Patent:
October 5, 2021
Assignee:
PIEDMONT RESEARCH & DEVELOPMENT CORPORATION
Abstract: The invention discloses novel dietary supplements or herbal product comprising at least one ingredient selected from the extracts or fractions derived from Bauhinia racemosa fruit, Cassia auriculata, Mangifera indica stem bark, Woodfordia fruticosa tender stem and Acacia nilotica fruit or their compositions in combination with at least one compound selected from biological actives, herbal extracts, minerals, amino acids, proteins, vitamins, excipient, diluent or carrier as a natural energy enhancer to provide an onset and steady maintenance of energy and for improving muscle strength, muscle mass and mental alertness, for treating sarcopenia and muscular atrophy in a warm blooded animal or mammal in need thereof.
Abstract: The invention relates to methods of producing extracts from cannabis plant material, where the extracts comprise cannabinoids and terpenes. The methods comprise extracting fresh or dried plant material with a cold organic solvent. The methods allow for the extraction of cannabinoids and terpenes, while leaving behind impurities such as waxes and chlorophyll that are commonly found in extractions with room temperature (RT) or warm solvent extraction methods. The methods can produce extracts having more than 90% cannabinoids.
Type:
Grant
Filed:
August 21, 2020
Date of Patent:
September 7, 2021
Assignee:
Neptune Wellness Solutions Inc.
Inventors:
Fereshteh Farokhi, Pierre St-Jean, Etienne Villeneuve
Abstract: Disclosed is a method of exfoliating skin. The method can include topically applying an effective amount of a composition to skin in need thereof. The composition can include an alpha hydroxy acid, 4-tert-butylcyclohexanol, an aqueous extract of plankton comprising an exopolysacchride synthesized by Vibo alginolyticus, an aqueous extract of Phragmites communis, an aqueous extract of Poria cocos, and an aqueous extract of Cucurbita pepo (pumpkin) seed.
Type:
Grant
Filed:
August 20, 2019
Date of Patent:
August 31, 2021
Assignee:
Mary Kay Inc.
Inventors:
David Gan, Geetha Kalahasti, Lisha VanPelt
Abstract: Methods are described herein for making a composition comprising at least one of caffeic acid, monocaffeoylquinic acids, and dicaffeoylquinic acids, and salts thereof.
Abstract: A homeopathic pain topical analgesic composition based on snake venom is disclosed. The study product also contained of Arnica montana, a homeopathic remedy most frequently used for fractures, bruises, and muscle strains due to its analgesic and anti-inflammatory effects. The composition also contained a penetrant component to enhance penetration of the ingredients as well as an analgesic/anti-inflammatory component. The snake venoms used may include those of Naja naja, Crotalus horridus and Lachesis muta. A clinical study of a product formulated in this way was effective in promoting relief from muscle pain and discomfort.
Type:
Grant
Filed:
January 21, 2020
Date of Patent:
August 17, 2021
Assignee:
Nature's Innovation, Inc.
Inventors:
William S. Carlson, Michael J. Rourk, Holly E. Carpenter
Abstract: The disclosure relates to a method for alleviating cancer pain and/or treating cancer skin inflammation in a subject in need of such treatment; the soybean seed extract composition comprises a soybean seed extract and a soybean seed vapor fraction.
Abstract: The present invention encompasses oils that have anti-inflammatory or resolution-stimulating activity that contain or are enriched with Specialized Proresolving Mediators (SPM) or SPM precursors, which originate from an oil obtained from organisms containing long chain omega-3 polyunsaturated fatty acids, such as fish, crustaceae, algae, and mollusks. The invention also encompasses a method for the production of these oils, and the utilization of the oils for nutritional supplements, pharmaceutical formulations, and cosmetic formulations, which can be employed for treating an inflammatory condition.
Type:
Grant
Filed:
March 8, 2019
Date of Patent:
August 3, 2021
Assignee:
Solutex NA LLC
Inventors:
Gerhardus Lucas Bannenberg, Charles Nicholas Serhan, Fernando Moreno Egea
Abstract: A method is for the extraction of a phytochemical, e.g., peptide or protein, or a chemical element from a macroalgae, by applying pulsed electric field (PEF)- or continuous electric field (CEF)-treatment to the macroalgae in a solvent, under pressure higher than the ambient pressure. A device and system carry out this method.
Abstract: The present invention encompasses oils that have anti-inflammatory or resolution-stimulating activity that contain or are enriched with Specialized Proresolving Mediators (SPM) or SPM precursors, which originate from an oil obtained from organisms containing long chain omega-3 polyunsaturated fatty acids, such as fish, crustaceae, algae, and mollusks. The invention also encompasses a method for the production of these oils, and the utilization of the oils for nutritional supplements, pharmaceutical formulations, and cosmetic formulations, which can be employed for treating an inflammatory condition.
Type:
Grant
Filed:
February 1, 2021
Date of Patent:
August 3, 2021
Assignee:
Solutex NA LLC
Inventors:
Gerhardus Lucas Bannenberg, Charles Nicholas Serhan, Fernando Moreno Egea
Abstract: The composition having hydrolyzed collagen and Manuka honey includes hydrolyzed collagen in an amount ranging from between 5% to 95% by weight and Manuka honey in an amount ranging from between 5% to not greater than 50% by weight in water. The Manuka honey can have a methylglyoxal concentration greater than 100 mg/kg, and preferably greater than 550 mg/kg.
Abstract: A pharmaceutical composition for preventing or treating inflammatory disease comprising snake venom is disclosed. More specifically, the pharmaceutical composition or quasi-drug includes venom of Agkistrodon piscivorus piscivorus or Naja melanoleuca as an active ingredient. A method for preventing or treating inflammatory disease includes administering the venom of Agkistrodon piscivorus piscivorus or Naja melanoleuca to a subject. The composition can increase the expression of C-C chemokine receptor type 1 (CCR1) in a mouse where skin ulcer is induced and thus has an excellent effect of treating skin ulcers, and thus can be effectively used for the treatment of skin ulcers, in particular Behcet's disease or Buerger's disease.
Abstract: The present disclosure provides a neuron activator that activates neurons. The neuron activator includes at least one selected from the group consisting of a dopamine production promotor that promotes dopamine production of the neurons, a neuron extension promotor that promotes extension of the neurons, and an amyloid ? resistance enhancer that enhances resistance of the neurons against amyloid ?. The neuron activator includes 6-methylsulfinylhexyl isothiocyanates or glycosides thereof, and at least one selected from the group consisting of unsaturated fatty acid and polyphenol.
Abstract: Methods in which an extract of Salvia miltiorrhiza roots is applied to the skin for a soothing cosmetic topical treatment. The invention also concerns a particular extract of Salvia miltiorrhiza roots, as well as compositions containing this extract and a cosmetic treatment method providing a soothing effect to the skin.
Abstract: A sprayable insecticidal and pupicidal composition (solution) for immobilizing and killing adult houseflies and pupa while being nonabrasive, nontoxic, and ingestible for humans and human contact. Effective amounts of dioctyl sodium sulfosuccinate is an active ingredient in the solution. The solution may further include effective amounts of glycerin as an active ingredient in the solution. The solution may further include a scented fragrance, namely, anise, for providing an aromatic characteristic to the solution.
Abstract: The present invention is directed to a new kind of medicinal value or health care function of Eurycoma longifolia extracts, particularly in the treatment or alleviation symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. In one aspect, the present invention discloses the use of a composition comprising a therapeutically effective amount of Eurycoma longifolia extract in the manufacture of a medicament for the alleviation of symptoms and/or conditions associated to hormonal imbalance in females, including menopause and its related symptoms. The alleviation of the symptoms and/or conditions according to the present invention is characterised by inducing a change in the hormonal contents of estrogen, progesterone, follicle stimulating hormone (FSH) and luteinizing hormone (LH). Also disclosed is the use of a pharmaceutical composition comprising the therapeutically effective amount of Eurycoma longifolia extract.
Type:
Grant
Filed:
October 15, 2019
Date of Patent:
July 13, 2021
Assignee:
BIOTROPICS MALAYSIA BERHAD
Inventors:
Tengku Shahrir Tengku Adnan, Annie George, Sasikala M. Chinnappan
Abstract: A composition for facilitating eyelash and/or eyebrow growth which includes at least forskolin derived exclusively from Coleus forskohlii and at least one keratmocyte growth stimulator. In some embodiments, the keratinocyte growth stimulator may be at least one plant extract, wherein the at least one plant extract is selected from a group comprising: Tussilago farfara flower extract, Achillea millefolium extract, Cinchona succirubra bark extract, Nasturtium officinale, Tropaeolum majus. The composition may also comprise a lipid phase, comprising castor oil.
Type:
Grant
Filed:
June 28, 2017
Date of Patent:
June 29, 2021
Inventors:
Lauren Jean Bilon, Brett Bilon, Irene Schnell
Abstract: The invention relates to a hydroalcoholic extract of the aerial parts of Schinus molle. The invention is characterised in that it comprises predominantly quercitrin and miquelianin among the extracted polyphenols, in a concentration, respectively, of at least 0.04% of quercitrin by weight of the total weight of the extract, and of at least 0.02% of miquelianin by weight of the total weight of the extract, the other extracted polyphenols, considered independently of one another, being present in trace form. The invention also relates to a method for preparing an extract of Schinus molle according to the invention and to cosmetic compositions comprising an effective amount of the extract according to the invention as protective active agent, and the cosmetic use of such compositions to improve the barrier function of the skin and to protect the skin against atmospheric pollutants.
Abstract: An object of the present invention is to provide a feed for domestic animals or a supplement for domestic animals, a growth-promoting agent for a bacterium of the genus Lactobacillus, and a method for promoting growth of a bacterium of the genus Lactobacillus, by which an intestinal environment of the domestic animal can be ameliorated without externally administering bacteria, and more specifically, a proportion of bacteria of the genus Lactobacillus in intestinal bacteria can be increased. According to the present invention, there is provided a feed for domestic animals or a supplement for domestic animals, which is used for promoting growth of a bacterium of the genus Lactobacillus in the domestic animal, the feed or the supplement including at least one of a plant of the genus Salacia, an extract of the plant of the genus Salacia, or a ground product of the plant of the genus Salacia.