Abstract: The present invention relates to the use of glucomoringin (GMG) and of the corresponding isothiocyanate derivative glucomoringin des-thioglucoside (GMG-ITC) as modulators of peripheral pain with specific reference to that linked with diabetic peripheral neuropathy and chemotherapy-induced neuropathy.
Abstract: A composition for treating erectile dysfunction in a male mammal comprising an Orchis anatolica root bulb extract. A method of treating erectile dysfunction in a mammal comprises administering a therapeutically effective amount of Orchis anatolica root bulbs alcohol extract in a male mammal.
Type:
Grant
Filed:
October 9, 2019
Date of Patent:
June 8, 2021
Assignee:
JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
Abstract: The invention describes methods and agents for inducing in the skin one or more effects selected from stimulating fibroblast migration, stimulating elastin production, reducing expression of inflammatory factors and upregulating specific genes, thereby preventing skin cell aging processes and repairing skin damage. In preferred embodiments, the methods and agents comprise active extracts produced from fish eggs.
Type:
Grant
Filed:
December 6, 2013
Date of Patent:
May 18, 2021
Assignee:
REGENICS AS
Inventors:
Runhild Gammelsaeter, Jan Remmereit, Gry Kalstad Lonne, Camilla Margrethe Haglerod
Abstract: The present invention relates to a cosmetic composition for wrinkle reduction comprising, as an active ingredient, a Gynostemma pentaphyllum gypenoside fraction and, more specifically, to a cosmetic composition for wrinkle reduction, wherein the Gynostemma pentaphyllum gypenoside fraction includes at least one gypenoside selected from the group consisting of gypenoside UL1, gypenoside UL2, gypenoside UL3, gypenoside UL4, gypenoside UL5, gypenoside UL6, and gypenoside UL7.
Type:
Grant
Filed:
June 10, 2016
Date of Patent:
May 18, 2021
Assignee:
CELLTRION, INC.
Inventors:
Young Jun Park, Kee Won Yu, Jae Hun Kim, Yeon Sook Kim, Seung Ki Lee, Joo Hyuck Lim, Jong Mook Kim, Chi Ho Choi, Ju Yeon Kim, Jung Yun Kim, Sung Ho Moon
Abstract: The present invention provides a therapeutic composition comprising heat-treated clear tomato concentrate (CTC), which has been found to possess both anti-inflammatory and bone-health promoting effects. The present invention is also directed to a composition comprising heat-treated CTC in combination with one or more carotenoids.
Abstract: Provided is a composition for relieving a hangover including as its active ingredients Corylus heterophylla Fisher nut extract, Alnus japonica Steud. stem extract and Sorbus commixta fruit extract. It is verified the composition for relieving a hangover according to the present disclosure reduces blood alcohol concentration more significantly than the composition for relieving a hangover including as its active ingredients Alnus japonica Steud. extract and Sorbus commixta extract as disclosed in Korean Patent Registration No. 181168 in in vivo tests (including animal testing and human experiment) and that has effects of considerably alleviating various hangover symptoms.
Abstract: A process for fractionating a plant material to provide isolated extractives, the process includes pretreating the plant material to provide a fluidized plant material, subjecting the pretreated fluidized plant material to high frequency pulses and shear forces without denaturing bioactive aspects of one or more components of the plant material to provide a first liquid fraction having extractives to be isolated and a first fractionated plant material, separating the first liquid fraction having extractives from the first fractionated plant material, and isolating extractives from the first liquid fraction.
Type:
Grant
Filed:
November 30, 2018
Date of Patent:
April 20, 2021
Assignee:
Green Extraction Technologies
Inventors:
Melvin Mitchell, James Etson Brandenburg
Abstract: Disclosed here are compositions comprising a curcuminoid-peptide complex. Also disclosed are methods of preparing a curcuminoid-peptide complex, comprising obtaining a curcuminoid; obtaining a peptide; and mixing the curcuminoid and the peptide in a solvent. Also disclosed are methods of treating a subject, the method comprising identifying a subject in need of treatment of a curcumin-related disorder, and administering to the subject a therapeutic composition comprising a curcuminoid-peptide complex as described. Also disclosed are therapeutic compositions comprising a curcuminoid-peptide complex as described and a pharmaceutically acceptable excipient, diluent, or carrier.
Type:
Grant
Filed:
May 12, 2015
Date of Patent:
April 6, 2021
Assignees:
HAUS BIOCEUTICALS, INC., RIXOMA, INC.
Inventors:
Adam J. Payne, Michael Centola, John Chancey
Abstract: Disclosed is a method of treating and/or preventing atopic dermatitis (AD) in a subject in need thereof, wherein the method comprises administering to the subject a therapeutically effective amount of a composition comprising a Sanguisorba officinalis root extract, an Ailanthus altissima bark extract, a Rheum palmatum root extract, a Cnidium monnieri fruit extract, a Scutellaria baicalensis root extract, and Glycyrrhiza glabra root extract thereby treating and/or preventing AD in the subject.
Type:
Grant
Filed:
February 20, 2018
Date of Patent:
April 6, 2021
Assignee:
KAMEDIS LTD.
Inventors:
Sharon Rozenblat, Yonit Bomstein, Jonathan Marder
Abstract: The custard apple peel nanoparticles may be manufactured by extracting custard apple peels in a solvent, spraying the custard apple peel extracts into boiling water under ultrasonic conditions to produce a first mixture, sonicating the mixture, stirring the mixture, and drying the mixture to obtain custard apple peel nanoparticles. In an embodiment, the custard apple peel may be peel of Annona reticulata. In an embodiment, the custard apple peel nanoparticles may have improved antibacterial or antioxidant properties.
Type:
Grant
Filed:
April 5, 2019
Date of Patent:
April 6, 2021
Assignee:
King Saud University
Inventors:
Hany M. Yehia, Hatem Salama Ali, Ebtesam Mohammed Al Olayan, Manal Fawzy Elkhadragy, Mohamed Fekry Mansour Serag Eldin, Manal Ahmed Awad
Abstract: The present invention discloses a process for modifying the natural composition of tocotrienol-rich fraction to achieve a product with reduced ?-tocopherol content, enhanced ?- and ?-tocotrienol content and also with an enriched total tocotrienol concentration.
Abstract: The main objective of the present invention is to develop an herbal formulation with high polyphenol concentrations. A therapeutic effect of ingredients in herbal composition with Antioxidants, Anti-inflammatories, Anti Viral & Anti Microbial properties to reduce Oxidative Stress, Inflammation, Viral and Microbial Infections. The herbal composition promotes management of diabetes, regulation of cholesterol, also immune system processes that helps to fight against viral and bacterial infections, colds, or the flu, skin ailments such as Psoriasis & eczema. Herbal Composition comprises synergistic combination of Moringa Oleifera Leaf Powder, Spirulina & Aqueous extracts of Oregano Vulgare Leaf Extract, Shilajit extract, Rosemary Leaf extract, Pomegranate Fruit Preel extract, Amla fruit extract, Fenugreek Seed Extract, Curcumin Extract, Piperine extract. Therefore, the chosen herbal blend provides the body with all of the vitamins, minerals, and nutrients it needs to continuously boost health.
Abstract: The present invention is directed to a method and device to isolate compounds from plant material using vibrational pulsing, vibrational decanting, vibrational sieving and vibrational rinsing. A susceptible liquid is generated by vibrational agitation, decanted when in a vibrating container and then collected by passing over a series of vibrating screens and then rinsed with water while collected on the vibrating screens and the residue collected. The isolated compound can either be collected in the decant or retained on the screens. In an embodiment of the invention, the vibrational rinsing step reduces unwanted impurities isolated.
Abstract: The present invention relates to a composition comprising a first onion extract (A), and liposomes, wherein at least a portion of the onion extract is encapsulated in the liposomes. Furthermore the present invention relates to a method for preparing a composition comprising a first onion extract (A), and liposomes, wherein at least a portion of the onion extract is encapsulated in the liposomes. Further, the present invention relates to a composition comprising an onion extract (A) (Allium cepa) and liposomes, obtainable by or obtained by the method. Furthermore, the present invention relates to compositions comprising a first onion extract (A), and liposomes, wherein at least a portion of the onion extract is encapsulated in the liposomes, for use in treating and/or preventing scars.
Type:
Grant
Filed:
October 5, 2017
Date of Patent:
April 6, 2021
Assignee:
HRA Pharma
Inventors:
Peter Boderke, Martina Heberer, Petra Scheppler
Abstract: The present invention relates to a cosmetic composition comprising guacatonga extract (Casearia silvestris), aroeira extract (Schinus tere-binthifolius raddi) and cosmetically acceptable adjuvants, for preventing and/or treating signs of skin aging. It further relates to the use of guagatonga extract (Casearia silvestris) and aroeira extract (Schinus terebinthifolius raddi) in the preparation of a cosmetic composition for preventing and/or treating signs of skin aging, as well as the use of this composition for simultaneously increasing tropoelastin, increasing the lysyl exidase (LOX) enzyme and reducing the activity of elastase in the dermis. The invention relates to a method of preventing and/or treating signs of skin aging, which comprises applying said cosmetic composition to the skin. Finally, the invention relates to a method of preparing said composition according to the present invention.
Type:
Grant
Filed:
September 8, 2014
Date of Patent:
April 6, 2021
Assignee:
NATURA COSMÉTICOS S.A.
Inventors:
Kelen Fabiola Arroteia, Cintia Rosa Ferrari, Renata Hannel Bueloni, Juliana Carvalhães Lago, Rhaisa Thaís Paulineli Navas, Pâmela Araújo Rodrigues Muchiutti, Icaro De Assis Santos, Carolina Iatesta Domenico, Daniela Zimbardi, Rosa Maria Teixeira Tagé Biaggio, Alan Passero, Soraya Baione De Moura, Ana Paula Pedroso De Oliveira
Abstract: A use of an emblica extract in preparing a pharmaceutical composition for protecting mitochondria in retina is provided. When the pharmaceutical composition, which comprises the emblica extract, is provided to retinal cells, a use of the pharmaceutical composition comprises improvement of the ability of performing the oxidative phosphorylation for the synthesis of the adenosine triphosphate (ATP) by the mitochondria in the retinal cells under or exposed to ultraviolet light, and improvement of the coupling efficiency of the synthesis of the adenosine triphosphate by the mitochondria.
Abstract: This invention provides a method of using extract of Cistanche tubulosa. The extract was used to prevent, slow down, or treat an eye disease caused by oxidative stress. The method includes administrating to a subject in need a therapeutically effective amount of the extract of Cistanche tubulosa to prevent, slow down, or treat an eye disease caused by oxidative stress.
Abstract: The present invention describes compositions for disinfection and/or effective preservation of food, for example fresh food, which allows the effective removal of microorganisms from these. The disclosed compositions contain derived extracts from plants with antimicrobial activity, which can act on their own or in combination with other disinfecting agents such as organic acids and chlorine compounds. The compositions of the invention are able to remove microbial contamination, including pathogenic microorganisms in seeds and sprouts obtained therefrom without changing the germination properties and nutritional and/or alimentary properties of the sprouts.
Type:
Grant
Filed:
May 17, 2013
Date of Patent:
April 6, 2021
Assignee:
Universidad Autonoma del Estado de Hidalgo
Inventors:
Javier Castro Rosas, Carlos Alberto Gómez Aldapa, José Roberto Villagómez Ibarra
Abstract: A refreshment towel with applied solution is an apparatus consisting of a carrying agent, most likely a high quality cotton towel or towelette, that has been saturated with an aqueous solution comprised of various ingredients. The resulting saturated towel can be rubbed on a user's skin such that the aqueous solution that has been absorbed by the towel is transferred. The aqueous solution is compounded specifically to provide cooling, insect repellant, sun protection, freshness, cleansing and other uses. More specifically, the aqueous solution is specially formulated so that desired sensory results take place when the towel comes in contact with the skin.