Abstract: Methods and products for delivering a medicament or agent to an individual are provided. The product includes a coating having a medicament or agent. The medicament or agent is present within the coating that surrounds a gum center (the water soluble portion and a water insoluble base portion). By chewing the gum, the medicament or agent is released from the product. Continuing to chew the chewing gum creates a pressure within the buccal cavity forcing the agent or medicament directly into the systemic system of the individual through the oral mucosa contained in the buccal cavity. This greatly enhances the absorption of the drug into the systemic system as well as the bioavailability of the drug within the system.

Abstract: The invention relates to a composition for treating keratin substances, in particular the hair, containing, in a cosmetically and/or dermatologically acceptable aqueous medium, at least: a) one zwitterionic polymer resulting from the copolymerization of at least one monomer of formula (I):  in which R1 and R2, which may be identical or different, represent a hydrogen atom or a methyl radical, and R3, R4 and R5, which may be identical or different, represent a linear or branched alkyl radical containing from 1 to 4 carbon atoms, Z represents an NH group or an oxygen atom, n is an integer from 2 to 5, A− is an anion derived from an organic or inorganic acid, and at least one monomer of formula (II): R6—CH═CR7—COOH  (II)  in which R6 and R7, which may be identical or different, represent a hydrogen atom or a methyl radical; the said polymer being soluble in water to a concentration of 1% by weight at a pH below 6 and at 20° C.

Abstract: A nail enamel composition which contains, in a cosmetically acceptable solvent system containing diacetone alcohol and at least one additional solvent chosen from C1-C6 alkyl acetates and C1-C6 alkyl alcohols, at least one film-forming substance and at least one urea-modified thixotropic agent. The use of this thixotropic agent in the specific solvent system gives nail enamel compositions with higher gloss, high clarity, improved aesthetics in the bottle, excellent thixotropic properties, and improved application properties.

Abstract: The present invention relates to a topical preparation containing spherical microparticles as the essential component, wherein the microparticles comprise water-insoluble linear polyglucan.

Abstract: The present invention provides methods for promoting healing of wounds which result from corneal resurfacing procedures, e.g. from laser surgery to alter refractive of the eye. The methods involve the application of a sheet of cultured epithelial cells to the laser corneal resurfacing wound of a subject in need of such treatment. The methods promote faster healing of corneal resurfacing wounds relative to prior art methods of healing such wounds. The invention also provides corneal wound healing devices having the shape and dimensions of a contact lens.

Abstract: The invention relates to a cosmetic composition for coating keratin fibers, comprising a cationic polymer, an anionic polymer and an aqueous dispersion of C1-C6 alkyl (meth)acrylate. The invention also relates to a process for coating keratin fibers which consists in applying the composition to the keratin fibers. The composition leads rapidly to a uniform make-up result which has good properties of coating, lengthening and curling the eyelashes, as well as good staying power.

Abstract: Methods and chewing gum formulations for delivering a medicament, namely sildenafil citrate, to an individual are provided. Further, an improved dosage form and method of treating erectile dysfunction are provided. Methods of treating esophageal spasms, dysphagia, and gastroparesis utilizing chewing gum formulations containing sildenafil citrate are also provided.

Abstract: The present invention relates to cosmetic compositions, comprising: a.) from about 0.01% to about 50%, by weight, of vitamin B3 compound; b.) from about 0% to about 90%, by weight, of an emollient component comprising from 0% to about 100%, by weight, of an oil liquid at ambient temperature; c.) from about 0.01% to about 40%, by weight, of a polar solvent; d.) from about 0% to about 90%, by weight, of a solidifying agent; and e.) from about 0% to about 90%, on an anhydrous basis, of a color wherein the vitamin B3 compound is added to the composition such that the concentration of the vitamin B3 compound exceeds the saturation solubility of the vitamin B3 compound in the polar solvent.

Abstract: The present invention relates to the use of compositions comprising the extract of the milk thistle plant, Silybum marianum, soybean protein and alpha tocopherol, either singly or in combination, in novel compositions for topical application on skin, hair and nails. More specifically, the present invention pertains to compositions for the above use, which are suitable for the entire skin. The present invention pertains to compositions for the above use, which are characterized in that they comprise milk thistle extract, soybean protein, and alpha tocopherol, either individually or in combination.

Abstract: The invention refers to a cosmetic product for hairs and decorative cosmetic with particular water resistance and wear (transfer) resistance. The product comprises stabile mixture of a water-emulsifiable, film-forming agent; a rheology modifier; a pigment; a volatile organic solvent; an oil soluble polymeric film-former; a silicon resin; and a filler.

Abstract: A pressed powder cosmetic composition comprising (A) a water-repellent and oil-repellent powder selected from the group consisting of a fluorine resin powder and a powder having a surface treated with a fluorine compound, (B) a film-forming polymer having a modulus of elasticity not greater than 200 kg/cm2, and (C) an oil. The composition according to the present invention is excellent in feeling upon use and does not crack easily.

Abstract: A waterborne composition for application to fingernails, toenails and acrylic nails by brush or spray is disclosed. The composition includes an emulsified resin binder, coalescents, plasticizers and one or more colored pigments. The composition is non-flammable, odorless, fast drying and environmentally safe. All ingredients in the composition are non-toxic.

Abstract: An active-substance-containing transdermal therapeutic system for the controlled release of estradiol or its pharmaceutically acceptable able derivatives alone or combined with gestagens consisting of a layer, an active-substance-containing reservoir which is bonded thereto and produced by using pressure sensitive adhesives, and a removable protective layer is characterized by the fact that the pressure sensitive adhesive comprises esters of colophony.

Abstract: The invention relates to a lip or care stick which contains vitamins and which is used for cosmetic applications. The stick contains an outer complex comprised of a cellulose derivative having a particle size ranging from 0.5 to 100 &mgr;m, and is comprised of a phospholipid and of an &agr;-tocopheral ester. The proportion of the complex is equal to 0.5 and 40 wt. %, with regard to the total mass. The stick also contains cosmetically conventional fats, waxes and additive which have a proportion ranging from 99.5 to 60 wt. % &agr;-tocopheral is stabilized with regard to UV-filters, can also be dissolved in the form of the complex by moisture and can be absorbed and processed as a vitamin by the body.

Abstract: A reshapable hair styling composition comprising, in a cosmetic vehicle appropriate for hair, at least one sulfonated polyurethane urea obtained by reacting: (a) at least one sulfonated polyol, (b) at least one non-sulfonated polyol, (c) at least one polyisocyanate selected from aliphatic and cycloaliphatic polyisocyanates, and (d) excess water, wherein the sulfonated polyurethane urea has been chain-extended.

Abstract: A cosmetic composition is provided that is particularly intended for application to areas constituting or surrounding the lips. It is a silicone-based formula, preferably comprising a solvent, masking oil, moisturizer, skin protectant, pigment, wax and antioxidant, specifically designed to enhance the fullness of the lips and their surrounding area which decrease as a result of the aging process. In addition, the cosmetic may be used to fill in wrinkles, cracks and/or crevices that surround the lip area which are also a result of the aging process. The invention is a creamy formula which easily fills such lines, resulting in a smooth texture of any areas to which it is applied. The effect is a reduction in the ability of facial lines to cause the undesirable bleeding of lipstick into areas of the face other than the lips.

Abstract: The present invention provides a method of preventing the appearance of fine lines, wrinkles and discoloration on the skin. This is achieved by the topical application to the skin of a composition containing a first platelet of alumina treated with a metal oxide, a second platelet treated with a spherical scattering component, and a cosmetic or pharmaceutical carrier. The compositions can also contain a standard interference pigment, such as a white and a yellow interference pigment to further blend the color to closely match the natural skin tone. The combination of pigments and platelets creates a mosaic of color and optically manipulates light such that lines, wrinkles, disfigurations and discolorations on the skin appear to substantially vanish. In addition to the pigments and platelet components, a non-interference pigment can also be added to fine-tune the matching of color to the skin tone.

Abstract: A non-laminar silicon oxide powder manufactured by a process comprising, a dissolution step wherein a concentration of 0.1-5.0M of a silicate which is in the range of 0<SiO2/Y2O<2 (Y: alkali metal atom) is dissolved in the presence of a cationic surfactant and the pH is 11 or more, a condensation step wherein the pH is adjusted to 10.5 or less and a rod-like micelle is formed with said cationic surfactant and a silicate is condensed on said rod-like micelle, and a removal step wherein said cationic surfactant is removed from the micelle state condensation which has an outer shell made of the silicate by said condensation. The silicon oxide powder is useful as a carrier for cosmetics, pharmaceutical drugs and perfumes.

Abstract: A cosmetic which includes from about one to about ten parts ethyl cellulose, from about one to about ten parts of a cosmetic pigment, from about 70 to about 95 parts of an organic solvent, and from about one to about ten parts of an alcohol soluble and water insoluble resin. The resin is a polymer which includes one or more of the following monomers: octylacrylamide, acrylate, butylaminoethyl methacrylate, and methyl methacrylate, hydroxypropyl methacrylate, polyvinyl acetate.

Abstract: A cosmetic composition, particularly useful as a base composition for mascara, containing fibers and at least three film formers: at least one tacky film former soluble or dispersible in water; at least one tacky film former soluble in oil; and at least one additional water-soluble or water-dispersible film former. The invention also relates to a method for pre-treating eyelashes prior to application of mascara and a method for providing volume and length to eyelashes using the inventive composition.