Patents Examined by Sam P. Siefke
  • Patent number: 9551661
    Abstract: An assay chip includes fluidic-channel member composed of a light-transmissive lower member and an upper member, forming a fluidic-channel therebetween, and a cover member fitted with the fluidic-channel member from the upper-member-side thereof. An inlet for injecting a sample solution into the fluidic-channel and a suction opening for sucking, from the downstream side, the injected sample solution, both communicating with the fluidic-channel, are formed on the upper surface of the upper member. A pot for carrying out predetermined pre-processing on the sample solution, a pot for first-reaction processing to bind a photoresponsive labeling substance to an analyte in the sample solution, an inlet insertion-hole for inserting the inlet, and a suction-opening insertion-hole for inserting the suction opening are linearly arranged on the upper surface of the cover member.
    Type: Grant
    Filed: June 6, 2013
    Date of Patent: January 24, 2017
    Assignee: FUJIFILM Corporation
    Inventors: Toshihito Kimura, Akihiro Komatsu, Toshihiro Mori, Hideyuki Karaki, Nobuhiko Fujiwara, Kouta Katou, Tadahiro Matsuno
  • Patent number: 9551635
    Abstract: In accordance with an embodiment of a system for handling and processing chemical and/or biological samples, a MicroChamber comprises a substrate, a reservoir formed on the substrate for receiving a chemical and/or biological sample, and an encoder such as a barcode or other suitable device. The encoder encodes information describing at least one characteristic of the substrate and/or reservoir.
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: January 24, 2017
    Assignee: Biogenex Laboratories Inc.
    Inventors: Krishan L. Kalra, Wallace Chang, Ravishankar Melkote
  • Patent number: 9551701
    Abstract: A method for detecting an analyte in a bodily fluid includes placing the detector in contact with at least one metabolite resulting from the metabolism or degradation of the analyte. The contact between the detector and the metabolite produces an optically detectable signal. The detection method includes the detection of the metabolite only in gas form, said metabolite in gas form coming from the evaporation of at least a part of said metabolite. The detection is also carried out without contact between the bodily fluid and the detector. A dressing for implementing the detection method is also described.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: January 24, 2017
    Assignee: COMMISSARIAT À L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Gilles Marchand, Pierre Marcoux
  • Patent number: 9547014
    Abstract: The disclosure relates to methods of detecting a neural injury biomarker in a biological sample. The method includes subjecting a biological sample to an assay disclosed that produces a measurable signal and detecting the measurable signal. The presence or absence of the measurable signal indicates the presence or absence of the neural injury biomarker in the sample, and thereby diagnosing a subject as having a neural injury. The disclosure further relates to methods of determining the state of a subject's neural injury. Further disclosed are systems and devices useful in carrying out the methods disclosed.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: January 17, 2017
    Assignee: Cornell University
    Inventors: Alexander J. A. Travis, Roy Cohen
  • Patent number: 9523111
    Abstract: Provided is a diagnostic apparatus. The diagnostic apparatus includes a microfluidic chip including first and second measurement parts for respectively measuring an amount of hemoglobin and an active degree of an enzyme within a blood sample. The second measurement part of the microfluidic chip analyzes the active degree of the enzyme within the blood sample using voltammetry.
    Type: Grant
    Filed: April 12, 2016
    Date of Patent: December 20, 2016
    Assignee: ACCESS BIO, INC.
    Inventors: Jaean Jung, Jae-Kyoung Choi, Won-Jung Kim, Tae-Hee Koo, Min-A Park
  • Patent number: 9506910
    Abstract: In a urine component analysis device, a correlation storage section stores data indicating a correlation between a measured concentration in one urine and in total urine in one day for each of a first and second specific component in the urine excreted by a human. A data input section inputs data indicating a concentration of the first specific component and of the second specific component in one urine of a subject. A concentration of the first specific component and of the second specific component in total urine in one day are determined by performing conversion using the correlation stored in the correlation storage section based on the concentration of the first specific component and the second specific component in the one urine. A concentration ratio between the first specific component and the second specific component in total urine in one day is determined based on the results of conversion.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: November 29, 2016
    Assignees: OMRON HEALTHCARE CO., LTD., OMRON CORPORATION
    Inventors: Hideyuki Yamashita, Naoto Ohgami, Yutaro Okuno, Toshiyuki Iwahori, Hirotsugu Ueshima
  • Patent number: 9493815
    Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: November 15, 2016
    Assignee: AKONNI BIOSYSTEMS, INC.
    Inventors: Christopher G. Cooney, Peter Qiang Qu, Alexander Perov, Jennifer Parker
  • Patent number: 9494578
    Abstract: The present invention covers the integration and utility of accelerometer features into a clinical analysis system. For example, measurement of dynamic acceleration and orientation of a blood-testing instrument with respect to Earth's gravitational field may be used to determine reliability of a test procedure and optionally to provide corrective elements thereof.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: November 15, 2016
    Assignee: Abbott Point of Care Inc.
    Inventors: Gary Vandersleen, Pierre Emeric, Paul Wasserman, Narendra Soman, Graham Davis
  • Patent number: 9482639
    Abstract: Methods, systems, and apparatuses, including computer programs encoded on computer-readable media, for monitoring volatile chemicals. A system includes an radio-frequency identification (RFID) tag composed of a patterned metal. The patterned metal is configured to absorb a volatile chemical. The RFID tag includes a non-volatile memory configured to store identification data. The RFID tag also includes a receiver that receives a signal at a frequency in a frequency range. The frequency is based upon an amount of the volatile chemical absorbed in the patterned metal. A transmitter of the RFID tag transmits the identification data in response to receiving the signal. The strength of the transmitted identification data is based upon an amount of the absorbed volatile chemical.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: November 1, 2016
    Assignee: EMPIRE TECHNOLOGY DEVELOPMENT LLC
    Inventor: David Max Roundhill
  • Patent number: 9480985
    Abstract: Washing efficacy test apparatus (2) is provided which includes a holder (4) and a test soil device (6) for location with said holder (4). The test soil device (6) is in the form of sheet material with a test soil substance (34) provided thereon. The holder in one example includes two members (8, 10) between which the test soil device (6) is detachably attached so that the device (6) can be easily removed for inspection and maintained in a required orientation in the washing apparatus (2) in use.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: November 1, 2016
    Assignee: ALBERT BROWNE LTD.
    Inventor: Richard Bancroft
  • Patent number: 9476833
    Abstract: According to an example, methods for forming three-dimensional (3-D) nano-particle assemblies include depositing SES elements onto respective tips of nano-fingers, in which the nano-fingers are arranged in sufficiently close proximities to each other to enable the tips of groups of adjacent ones of the nano-fingers to come into sufficiently close proximities to each other to enable the SES elements on the tips to be bonded together when the nano-fingers are partially collapsed. The methods also include causing the nano-fingers to partially collapse toward adjacent ones of the nano-fingers to cause a plurality of SES elements on respective groups of the nano-fingers to be in relatively close proximities to each other and form respective clusters of SES elements, introducing additional particles that are to attach onto the clusters of SES elements, and causing the clusters of SES elements to detach from the nano-fingers.
    Type: Grant
    Filed: January 30, 2013
    Date of Patent: October 25, 2016
    Assignee: Hewlett-Packard Devleopment Company, L.P.
    Inventors: Steven J. Barcelo, Zhiyong Li, Ansoon Kim, Zhang-Lin Zhou, Gary Gibson
  • Patent number: 9474474
    Abstract: In an embodiment, a patient monitor, such as a pulse oximeter, functions as a spot check glucometer when in communication with a blood glucose strip reader. In an embodiment, communications between the patient monitor and the strip reader may optionally be encrypted. Embodiments also include the strip reader housed in a dongle configured to mate with a sensor port of the pulse oximeter.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: October 25, 2016
    Assignee: MASIMO CORPORATION
    Inventors: Marcelo M. Lamego, Jeroen Poeze, Cristiano Dalvi, Hung Vo, Ferdyan Lesmana, Gregory A. Olsen, Sean Merritt, Ashish Patel
  • Patent number: 9476879
    Abstract: A test strip detection system, comprising a test strip card (1) and a detection device (2); the test strip card (1) comprises a card box (16), a built-in test strip (15) and an electronic label (20) matched with the built-in test strip (15); the electronic label (20) stores parameters such as the standard working curve of an object to be detected and the like; the detection device (2) comprises an optical system (3), a photoelectric detector (4), an analog/digital converter (5), a data processing device (6), an electronic label read-write module (10) with an aerial (11), a voice module (34), a cell box (7) and an output display device (8). The system further comprises a wireless communication module (12) and a wireless network system (13) connected with the wireless communication module (12) and comprising a remote server (14).
    Type: Grant
    Filed: October 30, 2012
    Date of Patent: October 25, 2016
    Assignee: CHENGDU LINGYU BIOTECHNOLOGY CO., LTD.
    Inventors: Yicai Ma, Min Gu, Ling Ma
  • Patent number: 9463460
    Abstract: A microfluidic device of the present invention is connected to at least an inlet to permit at least a stream of fluid with a desired fluid flow rate and a stable laminar flow. A body with at least a non-deformable portion and a deformable portion is connected to the inlet. At least a microconduit of substantially reduced length and cross-section, integrally formed in said non-deformable and deformable portions, and connected to the inlet. The stable laminar flow of fluid transiting through the microconduit is disrupted, resulting in a turbulent flow of the fluid, with a vibration of the deformable portion, when the fluid flow rate crosses a threshold value. The turbulent flow of the fluid undergoes an enhanced mixing, in a reduced period of time. At least an outlet is connected to microconduit to collect the mixed fluid. A network of microfluidic devices are arranged to perform mixing of fluids.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: October 11, 2016
    Assignee: INDIAN INSTITUTE OF SCIENCE
    Inventors: V Kumaran, Mohan K. S. Verma
  • Patent number: 9463463
    Abstract: A glucose test device and its carrying unit are provided. The glucose test device includes a housing, the carrying unit, a first push rod, and a second push rod. The carrying unit is detachably assembled in the housing. The carrying unit includes a first cartridge, lancets, a second cartridge, and strips. The first cartridge has first perforated grooves, and the lancets are slidably disposed in the first perforated grooves respectively. The second cartridge is adjacent to the first cartridge, and the second cartridge has second perforated grooves. The strips are slidably disposed in the second perforated grooves respectively. The first push rod as corresponding to the first cartridge is movably disposed in the housing. The second push rod as corresponding to the second cartridge is movably disposed in the housing, wherein the first push rod is parallel to the second push rod.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: October 11, 2016
    Assignees: LITE-ON ELECTRONICS (GUANGZHOU) LIMITED, Lite-On Technology Corporation
    Inventors: Sz-Shian He, Chia-Chun Wei, Hung-Wei Chen, Wei-Chieh Hu
  • Patent number: 9459227
    Abstract: Provided is a portable diagnostic test apparatus including: an accommodation portion including an outer side, an inner side, and an accommodation space provided on the inner side; a hinge; and a main body coupled to the accommodation portion by the hinge, where the portable diagnostic test apparatus is configured to be opened and closed by rotating one of the accommodation portion and the main body about the hinge, and where the main body is configured to obtain a result of a measurement based on data collected from drawn blood. The main body and/or the accommodation portion includes at least one strip keeping portion configured to store at least one strip. The at least one strip keeping portion may include: a housing; a discharge portion; and a first movement portion configured to move one of the strips to the discharge portion.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: October 4, 2016
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: In Duk Hwang, Yeon Moo Chung, Na Hui Kim, Jeong Je Park, Chul Ho Yun
  • Patent number: 9453787
    Abstract: A particle separation system uses a MEMS-based, microfabricated particle manipulation device which has an inlet channel, output channels, and a movable member formed on a substrate to sort one or more target particle from a sample stream. The system may include an interposer that receives the sorted particle and dispenses a carrier fluid with it to form a liquid droplet containing the particle. The droplet may then be dispensed to a microtiter plate, such that each well in the titer plate may contain a single target particle. The system may be used to separate individual biological cells, such as T cells, B cells, stem cells, cancer cells and sperm cells for further manipulation.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: September 27, 2016
    Assignee: Owl biomedical, Inc.
    Inventors: John S Foster, Nicholas C. Martinez
  • Patent number: 9448146
    Abstract: An automated sample processing system includes a sample input adapted to receive at least one sample container holder manually provided by a user, a consumable input adapted to receive one or more unused consumable supplies manually provided by a user, a waste output adapted to receive used consumable supplies, an automated processing apparatus, and a sample output, wherein the automated processing apparatus includes a decapper adapted to remove a lid from the at least one sample container, at least one agitator adapted to agitate and thereby homogenize the contents of the at least one sample container, a sample collector adapted to remove fluid specimen from the at least one sample container and transfer the specimen to at least one output carrier, and a capper adapted to replace the lid on the at least one sample container.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: September 20, 2016
    Assignee: HOLOGIC, INC.
    Inventors: Roy Ostgaard, Theodore S. Geiselman
  • Patent number: 9446403
    Abstract: A micro-channel chip comprises two gas control channels, a liquid inlet channel, a liquid outlet channel, a piston channel, and a micro pump including two micro-valves and a plurality of micro-channels. One of the gas control channels communicates with one end of the piston channel and communicates with the two micro-valves and the liquid inlet channel respectively via the micro-channels. The other one of the gas control channels communicates with the two micro-valves and the liquid outlet channel respectively via the micro-channels. The other end of the piston channel communicates with one of the micro-valves via the micro-channels.
    Type: Grant
    Filed: October 23, 2012
    Date of Patent: September 20, 2016
    Assignees: XIAMEN XINCHUANG BIOLOGICAL TECHNOLOGY CO., LTD.
    Inventor: Xingyue Peng
  • Patent number: 9448177
    Abstract: A flame photometric detector (FPD) for use in a gas chromatography (GC) apparatus is described. The FPD has an emission block that is maintained in a first temperature range, and a transfer line that is maintained in a second temperature range that is greater than the first temperature range. The FPD is coupled to a light detector, such as a photomultiplier tube (PMT).
    Type: Grant
    Filed: October 25, 2012
    Date of Patent: September 20, 2016
    Assignee: Agilent Technologies, Inc.
    Inventor: Robert P. Rhodes