Abstract: The invention relates to a process for distillatively preparing TDA from a reactant stream comprising TDA, high boilers and low boilers in a dividing wall column in which a dividing wall is disposed in the longitudinal direction of the column to form an upper combined column region (2), a lower combined column region (3), a feed section (4) having a rectifying section (5) and stripping section (6), and also a withdrawal section (7) having a rectifying section (9) and stripping section (8), which comprises the following steps: a. feeding the reactant stream (13) into the feed section (4) of the dividing wall column (1); b. drawing off a low boiler fraction via the top of the column (11); c. drawing off TDA via a side draw (14) in the withdrawal section (7) of the dividing wall column (1); d. drawing off a low boiler fraction via the bottom of the column (12).
Type:
Grant
Filed:
January 7, 2005
Date of Patent:
March 11, 2008
Assignee:
BASF Aktiengesellschaft
Inventors:
Carsten Knoesche, Martin Sohn, Ulrich Penzel, Hans-Juergen Pallasch, Gunter Georgi, Wolfgang Mackenroth, Hans Volkmar Schwarz, Stefan Maixner, Gerald Molz, Eckhard Stroefer
Abstract: The present invention concerns a process for producing silylalkylboranes containing the structural feature Si—C—B, new molecular silylalkylboranes, new molecular silylalkylborazines, new oligoborocarbosilazanes and polyborocarbosilazanes, a process for their production and their use as well as silicon boron carbide nitride ceramics and a process for their production.
Type:
Grant
Filed:
November 2, 2006
Date of Patent:
March 11, 2008
Assignee:
Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V.
Abstract: A process for preparing xylylenediamine by continuously hydrogenating liquid phthalonitrile over a heterogeneous catalyst in the presence of liquid ammonia in a reactor, which comprises mixing a stream of a phthalonitrile melt in liquid form by means of a mixer unit with a stream of liquid ammonia and conducting the liquid mixture into the hydrogenation reactor.
Abstract: A process for continuously preparing compounds containing SiOC groups, in which chlorosilane(s) are partially reacted with alcohol and optionally also with water in a prereactor, and the partial reaction product therefrom is fed to a first reaction unit comprising a column, reacted with alcohol and optionally water to give a crude product which still comprises volatile constituents, and the crude product is transferred to a second reaction unit comprising a column in which alcohol is additionally introduced, and freed there of volatile constituents, optionally in the presence of an unreactive organic solvent, the desired end product being removed at the lower end of the second reaction unit.
Abstract: A fluorine-containing acetylene alcohol represented by the following formula (1), wherein Rf is a linear or branched perfluoroalkyl group having 3 to 100 carbon atoms and may have an ether bond, —C—O—C—, Q is a divalent hydrocarbon group having 1 to 6 carbon atoms, and R1 is an alkyl group having 1 to 4 carbon atoms.
Abstract: A method for distillation of organosilicon compounds that contain acryloxy or methacryloxy groups characterized by subjecting an organosilicon compound (A) that contains acryloxy or methacryloxy groups to distillation in the presence of a polymerization inhibitor (B) and a compound (C) with aliphatic conjugated unsaturated bonds.
Abstract: This invention provides intermediates useful in a method of preparing amine stereoisomers. It also provides a method of preparing sulfoxide and sulfinylamine stereoisomers using certain of the intermediates.
Type:
Grant
Filed:
September 1, 2006
Date of Patent:
February 19, 2008
Assignee:
Apsinterm LLC
Inventors:
Zhengxu Han, Dhileepkumar Krishnamurthy, Chris Hugh Senanayake, Zhi-Hui Lu
Abstract: A new nitrogen-containing organosilicon compound contains tertiary amine groups and carbonyl groups wherein the tertiary amine groups are selected from R1R2N— (where R1 and R2 are the same or different univalent hydrocarbon groups of 1-15 carbon atoms), alicyclic amino groups, or heterocyclic amino groups containing in their rings one or more tertiary amine groups.
Abstract: A process for preparing amines of the general formula (I) R1R2CHNR3R4??(I) in which R1, R2, R3 and R4 are each independently hydrogen, straight-chain or branched, halogenated or halogen-free C1-C12-alkyl, C3-C12-cycloalkyl, C6-C10-aryl or C7-C11-aralkyl, by catalytic, hydrogenating amination of carbonyl compounds of the general formula (II) R1—C(?O)—R2??(II) with nitrogen compounds of the general formula (III) HNR3R4??(III) in the presence of bifunctional catalyst systems comprising a.) a hydrogenation-active catalyst component comprising one or more metals of transition group 8 of the Periodic Table and b.) one or more solid, acidic cocatalysts, wherein the hydrogenating amination is carried out in the presence of aqueous ammonia or aqueous amine of the formula (III) and at least one organic solvent miscible with ammonia or the aqueous amine of the formula (III).
Type:
Grant
Filed:
September 25, 2006
Date of Patent:
January 29, 2008
Assignee:
Clariant Speciality Fine Chemicals (Deutschland) GmbH
Inventors:
Daniel Schramm, Daniel Decker, Klaus Forstinger, Klemens Flick
Abstract: A process for preparing xylylenediamine, comprising the steps of ammoxidizing xylene to phthalonitrile by contacting the vaporous product of this ammoxidation stage directly with a liquid organic solvent (quench), removing products having a boiling point higher than phthalonitrile (high boilers) from the resulting quench solution or suspension and hydrogenating the phthalonitrile, wherein the organic solvent used for the quench is N-methyl-2-pyrrolidone (NMP), after the removal of the high boilers and before the hydrogenation, there is a partial or complete removal of the NMP and/or of products having a boiling point lower than phthalonitrile (low boilers) and the phthalonitrile for the hydrogenation step is dissolved or suspended in an organic solvent or in liquid ammon.
Type:
Grant
Filed:
September 4, 2004
Date of Patent:
January 29, 2008
Assignee:
BASF Aktiengesellschaft
Inventors:
Randolf Hugo, Sabine Jourdan, Kirsten Wenz, Thomas Preiss, Alexander Weck
Abstract: The invention relates to intermediate products and a new process for the production of benzocycloheptene C. The process for the production of its new intermediate products according to the invention starts from economical starting materials, provides the intermediate stages in high yields and high purity, without chromatographic purification steps, and allows production on an industrial scale.
Type:
Grant
Filed:
October 15, 2002
Date of Patent:
January 22, 2008
Assignee:
Schering Aktiengesellschaft
Inventors:
Johannes Platzek, Wolfgang Beckmann, Jens Geisler, Holger Kirstein, Ulrich Niedballa, Eckhard Ottow, Sigmar Radau, Claudia Schulz, Thomas Wessa
Abstract: Monomers for polymers having high oxygen permeability, high water content and a low modulus of elasticity are provided, and polymers and ophthalmic lenses comprised of said monomers are provided. They are monomers represented by formula (1) or (2) below: X—O—(CH2CH2CH2O)m—(CH2)n—A ??(1) wherein, X is a polymerizable group having carbon-carbon unsaturated bonds; A is a siloxanyl group; R is H or a methyl group; m is an integer of 1 to 10; m? is an integer of 2 to 10; and n is an integer of 2 to 10.
Abstract: The present invention provides improved methods for synthesis of phosphinothiol reagents, as well as novel protected reagents, for use in formation of amide bonds, and particularly, for peptide ligation. The invention provides phosphine-borane complexes useful as reagents in the formation of amide bonds, particularly for the formation of an amide bond between any two of an amino acid, a peptide, or a protein.
Type:
Grant
Filed:
September 19, 2005
Date of Patent:
January 8, 2008
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Ronald T. Raines, Laura L. Kiessling, Bradley L. Nilsson, Yi He, Matthew B. Soellner, Ronald J. Hinklin
Abstract: The present invention relates to (2-cyclopentenyl)chlorosilane derivatives and the preparation method thereof. In particular, it relates to a very economical process which reacts cyclopentadiene, which is formed by a cracking of industrially produced low-priced dicyclopentadiene, with a silane compound containing silicon-hydrogen bonds at elevated temperature in a hydrocarbon compound with a boiling point of a predetermined range, thus also enabling to prevent problematic production of dicyclopentadiene polymer by using the hydrocarbon compound. Further, in the presence of a group 10 metal compound catalyst, the process herein is capable of lowering the reaction temperature and increasing the yield in the reaction of sterically hindered alkyl-dichlorosilane. The (2-cyclopentenyl)chlorosilane may be useful in preparing an organic silicon compound containing an unsaturated group or a functional silicone polymer using the same, or in modifying the surface or manufacturing a thin layer.
Type:
Grant
Filed:
December 6, 2006
Date of Patent:
January 1, 2008
Assignee:
Korea Institute of Science and Technology
Inventors:
Bok Ryul Yoo, Joon Soo Han, Weon Cheol Lim
Abstract: N-heterocyclic moiety containing hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
Type:
Grant
Filed:
January 13, 2006
Date of Patent:
December 25, 2007
Assignee:
Pharmacia Corporation
Inventors:
John J. Talley, Daniel P. Getman, Gary A. DeCrescenzo, Kathryn L. Reed, Ko-Chung Lin, John N. Freskos, Michael Clare, Donald J. Rogier, Jr., Robert M. Heintz, Michael L. Vazquez, Richard A. Mueller
Abstract: The present invention relates to a process for the production of mixtures of di- and polyamines of the diphenylmethane series (MDA) containing less than 1,000 ppm of water and less than 200 ppm of aniline by reaction of aniline and formaldehyde in the presence of acid catalysts and subsequent separation of the acid catalyst and subsequent distillative separation of water and aniline in an at least a two-stage distillation including a flash evaporation and subsequent cooling.
Type:
Grant
Filed:
January 24, 2007
Date of Patent:
December 25, 2007
Assignee:
Bayer MaterialScience AG
Inventors:
Berthold Keggenhoff, Richard Adamson, Rudolf Uchdorf, Fritz Pohl
Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, p, q, Ar, R1 and R2 are as defined herein. Also provided are methods for preparing, compositions comprising, and methods for using compounds of formula I.
Type:
Grant
Filed:
December 21, 2005
Date of Patent:
December 25, 2007
Assignee:
Roche Palo Alto LLC
Inventors:
Robert Greenhouse, Ralph New Harris, III, Saul Jaime-Figueroa, James M. Kress, David Bruce Repke, Russell Stephen Stabler
Abstract: By reacting a halogenoalkyl group-bearing organosilicon compound and optionally sulfur with an aqueous solution or water dispersion of an ammonium or alkali metal polysulfide or a hydrate thereof in the presence of a phase transfer catalyst, a sulfide chain-bearing organosilicon compound having the average compositional formula (2): (R1O)(3-p)(R2)pSi—R3—Sm—R3—Si(OR1)(3-p)(R2)p??(2) wherein m has an average value of 2?m?6 is obtained in high yields and at a low cost with minimized formation of a monosulfide-bearing organosilicon compound.
Abstract: Toluenediamine is produced and separated from by-products of the reaction by: a) hydrogenating dinitrotoluene in the presence of a catalyst, b) separating the catalyst, water and optionally solvent from the hydrogenation reaction mixture to give crude toluenediamine, and c) separating by distillation the crude toluenediamine in a separating wall column into at least four product streams P1, P2, P3 and P4. The product stream P1 is a stream containing low boilers. The product stream P2 is a stream containing o-toluenediamine. The product stream P3 is a stream containing m-toluenediamine. The product stream P4 is a stream containing high boilers and m-toluenediamine.
Type:
Grant
Filed:
July 7, 2006
Date of Patent:
December 11, 2007
Assignee:
Bayer MaterialScience AG
Inventors:
Bernd Pennemann, Bill Brady, Rainer Buse, Gerd Greger