Patents Examined by Samuel P. Siefke
  • Patent number: 11513040
    Abstract: A sample staining device, comprising a staining platform provided with a staining solution and cleaning solution supply part; glass slide support structures located on either side of the staining platform and forming a certain clearance between a glass slide and the staining platform; and a glass slide driving mechanism that enables the glass slide to move while maintaining a certain clearance from the staining platform. When said device works, a staining solution is supplied to the staining platform, and a convex liquid surface is formed due to surface tension; when the glass slide moves to the convex liquid surface of the staining solution, the staining solution infiltrates and diffuses in the clearance formed between the staining platform and the glass slide to cover the glass slide so as to stain a sample; and after the glass slide is stained, a cleaning solution is supplied to clean the residual staining solution.
    Type: Grant
    Filed: June 22, 2017
    Date of Patent: November 29, 2022
    Assignee: AVE SCIENCE & TECHNOLOGY CO., LTD.
    Inventor: Jianwen Ding
  • Patent number: 11506625
    Abstract: A sensor device is provided to sample data from a fluid in a sealed environment. The sensor comprises a housing and a diamond within the housing. The housing is formed such that the device is reversibly insertable into the sealed environment so that the diamond directly interfaces with the sealed environment.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: November 22, 2022
    Assignee: UCL Business LTD
    Inventors: Richard B. Jackman, Ralph Jennings-Moors, Alexander C. Pakpour-Tabrizi, William Parfitt, Joseph O. Welch
  • Patent number: 11499983
    Abstract: [Task] To provide an automatic analysis apparatus including a photomultiplier tube which controls a sensitivity of the photomultiplier tube without adjusting a high voltage value. [Solution] An automatic analysis apparatus according to the present invention includes a photomultiplier tube which detects light from a reaction vessel; a determination unit which determines an output signal of the photomultiplier tube in a case where the photomultiplier tube is irradiated with first light; and a control unit which irradiates the photomultiplier tube with second light to lower a sensitivity of the photomultiplier tube in accordance with a determination result by the determination unit.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: November 15, 2022
    Assignee: Hitachi High-Tech Corporation
    Inventors: Shunichirou Nobuki, Koshin Hamasaki, Taku Sakazume, Yoshihiro Yamashita, Hidetsugu Tanoue, Tatsuki Takakura
  • Patent number: 11499917
    Abstract: An analyzing system is provided. The analyzing system includes a fluid container defining a sample chamber where a sample is contained in the sample chamber, and a sensor including a transparent body with a reverse face and an obverse face where the obverse face having a nanostructured surface. The nanostructured surface includes a plurality of elongate nanostructures having a respective longitudinal axis that is disposed substantially perpendicularly to the obverse face. The analyzing system includes an excitation and detection apparatus that includes an excitation source for generating a beam of polarized radiation and a corresponding radiation detector where the sensor is coupled to the fluid container such that the nanostructured surface is exposed to the sample chamber, to the sample located therein.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: November 15, 2022
    Assignee: Causeway Sensors Limited
    Inventors: Robert Pollard, Antony Murphy, Breandan Hill, Danny O'Connor
  • Patent number: 11493493
    Abstract: A hydrogen gas sensor with a substrate and a zinc oxide nanostructured thin film deposited on the substrate, wherein the zinc oxide nanostructured thin film has a lattice structure with a weight ratio of low binding energy O2? ions to medium binding energy oxygen vacancies in a range of 0.1 to 1.0, and a method of fabricating a gas sensor by thermally oxidizing a metal thin film under low oxygen partial pressure. Various combinations of embodiments of the hydrogen gas sensor and the method of fabricating the gas sensor are provided.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: November 8, 2022
    Assignee: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS
    Inventors: Qasem Ahmed Drmosh, Zain Hassan Yamani, Mohammad Kamal Hossain
  • Patent number: 11491489
    Abstract: A microfluidic group includes a female connector and a male needle connector. The female connector has a connector chamber in a containment body; a duct extending in the containment body to a duct opening on a first face of the connector chamber; a needle entry hole extending from a lateral face of the containment body to a second face, not facing the first face of the connector chamber; and a gasket arranged in the connector chamber. The gasket has a side wall internally delimiting a cavity and extending in part adjacent to the second face of the connector chamber. The cavity of the gasket faces the first face of the connector chamber.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: November 8, 2022
    Assignee: STMICROELECTRONICS S.r.l.
    Inventors: Marco Angelo Bianchessi, Lillo Raia
  • Patent number: 11485946
    Abstract: A device for storing, incubating or manipulating biological samples, in particular incubating device or shaking device, comprising a sample chamber, an irradiation chamber, and a holder with a UV light source, wherein a sidewall of the irradiation chamber comprises a first mounting member and wherein the holder comprises a second mounting member configured to interact with the first mounting member for pre-mounting the holder to the sidewall.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: November 1, 2022
    Assignee: Eppendorf AG
    Inventors: Paul Czajkowski, Erik Zamirowski
  • Patent number: 11485949
    Abstract: Disclosed is a microorganism inoculation device, which comprises a workbench, wherein support columns are provided on the upper surface of the workbench, a limiting plate is provided in the middle part of the supporting column, an injection head is provided in the middle part of the limiting plate, an air cylinder is provided in the middle part of the lower surface of the workbench, a piston rod of the air cylinder is fixedly connected with the middle part of the upper surface of a lifting plate, guide rods are provided on the upper surface of the lifting plate, the upper end of the guide rod is fixedly connected with a tray, the left and right sides of the upper surface of the tray are fixedly connected with the lower part of a fixed bracket, the middle part of the injection head is slidably connected with the limiting plate.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: November 1, 2022
    Inventor: Binlu Liu
  • Patent number: 11486831
    Abstract: A specimen measurement device which detects a measurement object material according to the present embodiment, includes: a magnetic field applicator configured to apply a magnetic field to a measurement cartridge including a substrate, a first substance fixed on the substrate and specifically reacting with the measurement object material, a magnetic particle, and a substance fixed on the magnetic particle and specifically acting with the measurement object material; a detector configured to detect light passing through the substrate; and a controller configured to control the magnetic field applicator to perform a first operation to apply a first magnetic field in a direction to move the magnetic particle away from the substrate when a specimen solution containing the measurement object material is introduced into the measurement cartridge, and then perform a second operation to apply a second magnetic field in a direction to move the magnetic particle toward the substrate.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: November 1, 2022
    Assignee: CANON MEDICAL SYSTEMS CORPORATION
    Inventors: Ichiro Tono, Takeshi Yamauchi, Shoichi Kanayama
  • Patent number: 11480565
    Abstract: An instrument for detecting signal from a biological sample includes a pipettor module configured to hold a plurality of pipettes in respective pipette positions, to hold liquid in one or more pipette tips, and to pipette liquid in and out of the one or more pipette tips. Each of the one or more pipette tips has a pipette tip point. The instrument further includes one or more magnets positioned such that each of the one or more pipette tips is adjacent one of the one or more magnets.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: October 25, 2022
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Shai Nimri, Yochanan Uri, Boaz Ran
  • Patent number: 11471889
    Abstract: A sample assembly includes a vial, a vial insert, and a sealing arrangement. The vial insert could be any combination of a sample chamber, a matrix, or a swab breaker configured to be positioned within the vial. The sealing arrangement includes a coupling portion and a cap assembly. The coupling portion defines a mounting channel sized to receive a portion of the vial. The coupling portion is configured to slidably couple to the vial. The cap assembly includes a desiccant cap. The desiccant cap is configured to couple to the vial to selectively form a sterile barrier between the sealing arrangement and the vial.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: October 18, 2022
    Assignee: Gentueri Inc.
    Inventors: Randolph James Nagy, Todd Bakken
  • Patent number: 11467094
    Abstract: Embodiments of the present disclosure provide for methods of detecting, sensors (e.g., chromogenic sensor), kits, compositions, and the like that related to or use tunable macroporous polymer. In an aspect, tunable macroporous materials as described herein can be used to determine the presence of a certain type(s) and quantity of liquid in a liquid mixture.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: October 11, 2022
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Sin Yen Leo, Peng Jiang, Tianwei Xie
  • Patent number: 11467054
    Abstract: Provided is a porous pellet for inclusion into an operating fluid of a fluid system for detecting sites of fluid leakage. The porous pellet comprises a solid matrix formed by at least one fluorescent dye which is solid at room temperature. The matrix has a porosity of from about 10% to about 90%. Methods of installing the porous pellets into fluid system for detection of leaks is also provided.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: October 11, 2022
    Assignee: Spectronics Corporation
    Inventors: Jonathan Daniel Cooper, Limin Chen, John Thomas Duerr, Jennifer Marie Hunt
  • Patent number: 11460383
    Abstract: Automated cell staining systems and methods are disclosed herein. In particular, the staining systems disclosed herein provide low-volume, automated bench top staining systems for staining biological samples contained on a cytological slide.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: October 4, 2022
    Assignees: NanoCytomics, LLC, Northwestern University
    Inventors: Sergey Rozhok, Justin R. Derbas, Jarema Czarnecki, Hariharan Subramanian
  • Patent number: 11460402
    Abstract: A method for detecting glutaraldehyde in a water sample in which Au-BSA nanoclusters have been introduced is provided. In the method, the water sample is mixed with the Au-BSA nanoclusters to form a mixture. The mixture is incubated for 2 to 10 minutes, and the glutaraldehyde present in the mixture reacts with the Au-BSA nanoclusters and causes fluorescence quenching of the Au-BSA nanoclusters. Then a fluorescence intensity of the quenched Au-BSA nanoclusters in the mixture is measured at an emission wavelength of 675 nm. A presence and concentration of glutaraldehyde in the water sample is then determined by comparing the measured fluorescence intensity of the quenched Au-BSA nanoclusters at the emission wavelength of 675 nm with fluorescence intensity values of calibration samples comprising Au-BSA nanoclusters and known glutaraldehyde concentrations.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: October 4, 2022
    Assignee: Saudi Arabian Oli Company
    Inventors: Xiangyang Zhu, Mohammed A. Al-Moniee, Mazen A. Al-Saleh
  • Patent number: 11458472
    Abstract: A liquid handling device having an axis of rotation about which the device can be rotated to drive liquid flow. The device includes a vented upstream chamber having an outlet port and an unvented chamber including an inlet port to receive liquid from the outlet port of the upstream chamber and an outlet port radially outward the inlet port. The device further includes a vented downstream chamber having an inlet port to receive liquid from the outlet port of the unvented chamber. A downstream conduit connects the outlet port of the unvented chamber to the inlet port of the downstream chamber and includes a bend radially inward of the outlet port of the unvented chamber. An upstream conduit connects the outlet port of the upstream chamber to the inlet port of the unvented chamber.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: October 4, 2022
    Assignee: Biosurfit, SA
    Inventors: Nuno Alexandre Esteves Reis, Tania Moura Pires De Andrade Tenreiro, Miguel Joao Marques Barreiros
  • Patent number: 11459538
    Abstract: Control of humidity in chemical reactors, and associated systems and methods, are generally described. In certain embodiments, the humidity within gas transport conduits and chambers can be controlled to inhibit unwanted condensation within gas transport pathways. By inhibiting condensation within gas transport pathways, clogging of such pathways can be limited (or eliminated) such that transport of gas can be more easily and controllably achieved. In addition, strategies for purging condensed liquid from chemical reactor systems are also described.
    Type: Grant
    Filed: October 16, 2019
    Date of Patent: October 4, 2022
    Assignees: Sanofi, Massachusetts Institute of Technology
    Inventors: Shireen Goh, Rajeev Jagga Ram, Kevin Shao-Kwan Lee, Michelangelo Canzoneri, Horst Blum
  • Patent number: 11453000
    Abstract: A flow cell and a method for connecting components of a microfluidic flow cell, in particular for integrating component parts into a carrier structure of the flow cell, in which a gap is formed between the components to be connected. The gap is filled with a solvent. The material of at least one component bordering the gap dissolves in the solvent and the material completely fills the width of the gap and partially fills the height thereof after evaporation of the solvent.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: September 27, 2022
    Assignee: THINXXS MICROTECHNOLOGY AG
    Inventor: Lutz Weber
  • Patent number: 11454581
    Abstract: The molecule detecting apparatus of an embodiment includes a light source 31, a fluorescent layer 42 emitting different fluorescence depending on the kind of a target molecule 60 captured when being irradiated with light from the light source 31, a photodetector 32 configured to detect fluorescence, and the photodetector 32 is an array of avalanche photodiodes operating in Geiger mode.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: September 27, 2022
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Honam Kwon, Ikuo Fujiwara, Kazuhiro Suzuki, Keita Sasaki, Yuki Nobusa, Yasushi Shinjo
  • Patent number: 11454570
    Abstract: In one embodiment, a sample probe has a cap and a base, wherein the cap includes a grip portion and a projection portion. The projection portion fits within a hollow portion of a filter such that the filter is disposed on the outside of the projection portion and the filter and the cap form a cap assemblage. The base comprises a base recess that receives a portion of the cap assemblage including the filter. The cap and base include corresponding media transfer regions adjacent and connected to the filter that reduces flow resistance and chances of blockage and/or contamination during dissolution-testing sampling using the sample probe.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: September 27, 2022
    Assignee: Distek, Inc.
    Inventors: Jeffrey Brinker, Shawn Craig, Peter K. Schultz, Timothy John Nadolski