Abstract: One aspect of the present disclosure relates to a system that provides an alternative to traditional treatments for sleep apnea. The system allows to apply an electrical stimulus through an electrode to stimulate an afferent nerve fiber while a patient is sleeping. The system also includes activating an endogenous central nervous system (CNS)-regulated reflex response to coordinate upper airway muscles based on the stimulation of the afferent nerve fiber. Based on the endogenous CNS-regulated reflex response, an airway patency in the sleeping patient can be regulated.

Abstract: A device for irradiation of the eye of a living subject with light such as UV light includes a structure (20) adapted to overlie the outer surface of the eye, the structure having an axis (28, 128) extending in a downward direction (D) towards the eye when the structure overlies the eye. A light scattering element (70, 158, 141) within the structure includes a peripheral portion remote from the axis and a central portion adjacent the axis. A plurality of transmission optical fibers (42, 157) in optical communication with the peripheral portion of the light scattering element at a plurality of locations spaced around the axis.

Abstract: An apparatus, system, and method directed to detecting a physiological signal during discrete time separated detection windows, deriving one or more respiratory disturbance indices from the physiological signal, detecting a respiratory disturbance state in response to the one or more respiratory disturbance indices deviating from a threshold value, interpolating the one or more respiratory disturbance indices between adjacent time separated detection windows, and declaring a respiratory disturbance episode based on the detected respiratory disturbance state during the detection windows and the interpolation between detection windows.

Abstract: The present invention relates to a medical skin wrinkle improvement device using a peak of a laser pulse wave, and more specifically, to a medical skin wrinkle improvement device using a peak of a laser pulse wave, thereby lowering the degree of carbonization of a skin tissue having the laser irradiated thereon, thus enhancing a skin generation effect and shortening recovery time.

Abstract: A neuromodulation targeting system includes a GUI that facilitates selection of one or more neuromodulation target regions. The GUI provides an interactive display representing anatomy of a patient with user-selectable portions corresponding to a plurality of predefined anatomical regions associated with distinct localized clinical effects of neuromodulation. The system further includes a targeting selector engine that is responsive to user selection of a first portion of the interactive display by configuring delivery of neuromodulation therapy to a first target region to produce a first localized clinical effect in the patient at a location corresponding to the first portion of the display, upon administration of the neuromodulation therapy to the patient.

Abstract: A device for radiating pulsed light toward a thrombus in a blood vessel includes a light source configured to output monitoring light to be radiated into the blood vessel, a light detector configured to detect returned light of the monitoring light and output a detection signal, and a computer configured to acquire a time waveform, which is a change in an intensity of the returned light over time, based on the detection signal, wherein the computer is configured to obtain a parameter on the basis of the time waveform and evaluates a reaction in the blood vessel according to the radiation of the pulsed light on the basis of the parameter.

Abstract: A system configured to determine a characteristic of a patient includes a plurality of sensors, wherein each sensor of the plurality of sensors is configured to noninvasively determine a respective parameter of the patient, and wherein the parameter determined by each sensor is different from parameters determined by remaining sensors of the plurality of sensors. Such a system also includes a connector having a passage configured to direct pressurized fluid therethrough, wherein the plurality of sensors is connected to the connector.

Abstract: An optical fiber puncture needle tubing comprises an optical fiber having a body portion and a head portion, one end of the tapered head is a tapered tail end having a tapered diameter; the periphery of the body portion is wrapped with a body tube, the cylindrical head is wrapped with a metal casing, and the periphery of the tapered head is wrapped with a polymer jacket. The polymer jacket is provided with an inverted-tooth structure or inverted kerf structure. Through the synergistic effect with various components, the puncture needle tubing can be transmitted fast in the long blood vessels, and can achieve higher light emission efficiency and therapeutic effect. The puncture needle tubing can be applied in fields of the treatment of photodynamic tumors, eliminating vascular obstructions or performing vascular puncture.

Abstract: A dual port switching apparatus (12) comprising a connection part for mounting to a base unit (11), an input beam port to receive a main laser beam from a base unit (11) in an input optical path (22), a first output port (14) for connection to a flexible wave guide, a second output port (15) for connection to an articulated arm (16), and a switching element (56) moveable between a first position and a second position to direct an input beam to one of the first output port (14) and the second output port (15).

Abstract: Provided is a simple light irradiation apparatus capable of performing uniform irradiation even on to a treatment area having a curved surface and capable of suppressing excessive heating caused by light irradiation. The light irradiation apparatus (10) includes a polymer gel layer (3) that covers the treatment area (2) on skin (1), an LED protective layer (6) that closely adheres to the polymer gel layer (3), and a substrate (5) on which LEDs (4) closely adhered to the LED protective layer (6) are arranged thereon. A current control apparatus (8) which lights the LEDs (4) controls irradiation intensity and stops irradiation when reaching a demanded dose amount.

Abstract: The invention relates to the field of cardiovascular resuscitation and, more specifically, it concerns a novel method of monitoring the ventriculo-aortic coupling of at-risk patients on the basis of the aortic pressure/flow loop of the patient and the zoning of this loop.

Abstract: A blood vessel optical fiber guide wire includes at least one of optical fiber core wire, a wire wrapping layer and a hydrophilic coating capable of improving compatibility with body liquids and reducing the resistance. The optical fiber core wire is disposed in a core of the optical fiber guide wire. The wire wrapping layer is formed from at least one of winding wire or winding sheet wrapping outside of the optical fiber core wire. The hydrophilic coating is coated outside of the wire wrapping layer. The optical fiber guide wire may enter a predetermined position in artery blood vessel of human body. The light can be guided into and/or guided out of a location of lesion so as to achieve the photodynamic treatment of diseases such as tumor in vivo. The need to diagnosis and treatment in the field including biology and medical treatment can be met.

Abstract: A surgical method and tool for establishing a steam bubble between a fiber tip and a surgical target. The device and process capable of maintaining the steam bubble by providing a low-power, continuous-wave laser emission. Furthermore, the method and tool capable of delivering to the surgical target through the steam bubble a therapeutic laser emission providing ablation of the surgical target.

Abstract: A memory metal optical fiber puncture needle tubing includes an optical fiber, a body tube, a metal casing and a split-shaped needle. The optical fiber has a body portion and a head portion. The head portion has a cylindrical head portion and a tapered head portion. The body tube surrounds the body portion. The metal casing is wrapped around the cylindrical head portion. The split-shaped needle is made of memory metal surrounding a periphery of the tapered head portion. The split-shaped needle has a plurality of tapered petals. When a temperature of the split-shaped needle is T0, the tapered petals are in a closed state such that the split-shaped needle is conical. When the temperature of the split-shaped needle is T1, the tapered petals are in an opened state such that the tapered head portion of the optical fiber is exposed.

Abstract: A mask device for facial skin care includes: an outer mask, which is formed to be spaced apart from a user's face at a predetermined interval, has a size to cover the whole face, and includes first and second eye protection holes located around the eyes and slots respectively formed at a left end portion and a right end portion; an LED module, and to which a control line receiving electric power connected to the controller of the outside and a control signal is connected; an inner mask, which is located outside the LED module, has a size to cover the hole face; and an eye protection member whose one end is combined to the first and second eye protection holes of the inner mask and the other end protrudes to come into contact with the user's eyes.

Abstract: Apparatus and methods of treating a hard lens region of an eye with a laser where one method includes identifying a boundary of the hard lens region, selecting a laser-parameter to enable a photo disruptive procedure in the hard lens region and to control a spreading of bubbles in the hard lens region, modifying a mechanical property of a posterior portion of the hard lens region in a proximity of the identified boundary by the photo disruptive procedure, and modifying a mechanical property of a portion anterior to the modified posterior portion of the hard lens region by the photo disruptive procedure. The laser bubbles can be applied to form incisions which are non-transverse to an axis of the eye and intersect the lens fibers.

Abstract: A hand-held electromechanical surgical device configured to selectively connect with a surgical accessory, is provided and includes a handle assembly having a power pack with a core assembly. The core assembly includes a plurality of motors, with each motor having a rotatable drive shaft extending therefrom, wherein each drive shaft is parallel to one another; a processor connected to and configured to control each motor; and a battery electrically connected to the processor and each motor. The power pack includes an inner housing encasing at least the plurality of motors, the processor, and the battery. The handle assembly includes an outer shell housing configured to selectively encase substantially the entire power pack therein, wherein a rotation from each rotatable drive shaft of each motor is transmitted through the inner housing and the outer shell housing.

Abstract: A method of laser irradiation for alleviating the physical symptoms associated with acute or chronic inflammatory conditions, which can include directing a laser beam from a laser unit in a continuous wave operation having a wavelength of approximately 1275 nm and a power output level in the range of from one (1) Watt up to and including 75 Watts on an inflamed area that is to be treated, such that the laser beam penetrates the inflamed area in the range of from 0.1 cm to 30 cm. In addition, the laser beam from the laser unit can be configured to activate intracellular photoreceptors, thereby initiating a cascade of secondary cellular metabolic effects and normalizing cellular activity towards homeostasis.

Abstract: An apparatus comprises a sensor for measuring a physiological parameter of a subject, wherein the physiological parameter sensor is adapted to be worn by the subject; an actuator comprising an electro-active polymer material, EAP, portion for adjusting the position of the physiological parameter sensor relative to the subject; a feedback sensor for measuring movement of the physiological parameter sensor and/or the subject; a controller configured to process the measurements of the feedback sensor and to adjust the position of the actuator based on information from the feedback sensor.

Abstract: A Laser system is disclosed which comprises a pump, wherein the laser system is adapted to be operated in pulsed operation so that at least one individual pulse of a temporally limited pulse duration (T0) is generated, wherein the pulse ablates a material such that a debris cloud forms above the ablated material. Further, the pump power of the pump is modulated in such a way that the following three conditions are fulfilled: (1) the intensity of the pulse oscillates between maximum values and minimum values during the pulse duration, wherein the laser pulse comprises a plurality of intensity maxima Imax which occur at times {Ti, i=1, . . . N}; and a plurality of intensity minima Imin which occur at times {tk, k=1, . . .