Abstract: Described herein are methods, devices, and systems that monitor heart rate and/or for arrhythmic episodes based on sensed intervals that can include true R-R intervals as well as over-sensed R-R intervals. True R-R intervals are initially identified from an ordered list of the sensed intervals by comparing individual sensed intervals to a sum of an immediately preceding two intervals, and/or an immediately following two intervals. True R-R intervals are also identified by comparing sensed intervals to a mean or median of durations of sensed intervals already identified as true R-R intervals. Individual intervals in a remaining ordered list of sensed intervals (from which true R-R intervals have been removed) are classified as either a short interval or a long interval, and over-sensed R-R intervals are identified based on the results thereof. Such embodiments can be used, e.g., to reduce the reporting of and/or inappropriate responses to false positive tachycardia detections.

Abstract: A system monitors an individual for conditions indicating a possibility of occurrence of irregular heart events. A database includes a plurality of combinations of at least a first signature and a second signature. A first portion of the plurality of combinations is associated with a normal heartbeat and a second portion of the plurality of combinations is associated with an irregular heart event. A wearable heart monitor that is worn on a body of the patient includes a heart sensor for generating a heart signal responsive to monitoring a beating of a heart of the individual. The monitor further includes a processor for receiving the heart signal from the heart sensor. The processor is configured to analyze the heart signal using a plurality of different processes. Each of the plurality of different processes generates at least one of the first signature and the second signature.

Abstract: A physiological data detection method is provided. The physiological data detection method includes the following steps. Firstly, an ECG signal and a PPG signal are detected. Then, a plurality of RRI values is calculated according to the ECG signal, and a plurality of PPI values is calculated according to the PPG signal. Thereafter, wrong RRI values are excluded according to the RRI values and/or the PPI values. Then, whether an abnormal state occurs or not is determined by using the remaining RRI values. A wearable device therefor is also provided.

Abstract: A hermetically sealed feedthrough assembly for an active implantable medical device having an oxide-resistant electrical attachment for connection to an EMI filter, an EMI filter circuit board, an AIMD circuit board, or AIMD electronics. The oxide-resistant electrical attachment, including an oxide-resistant sputter layer 165 is disposed on the device side surface of the hermetic seal ferrule over which an ECA stripe is provided. The ECA stripe may comprise one of a thermal-setting electrically conductive adhesive, an electrically conductive polymer, an electrically conductive epoxy, an electrically conductive silicone, an electrically conductive polyimide, or a thermal-setting electrically conductive polyimide, such as those manufactured by Ablestick Corporation.

Abstract: A method for measuring and analyzing blood pressure using PPG includes receiving, by a computer, a PPG signal from a finger of a subject, dividing, by the computer, a normalization pulse wave signal derived from the received PPG signal into one or more predetermined windows, extracting, by the computer, a maximum lower amplitude value from one of the respective divided windows, extracting, by the computer, a target feature pattern from the extracted maximum lower amplitude value, deriving, by the computer, a first target unique vector and a second target unique vector with respect to the target feature pattern, using a linear discriminant analysis (LDA) algorithm to display the first target unique vector and the second target unique vector of the target feature pattern on 2-dimensional (2D) graph, and providing, by the computer, a blood pressure state of the subject, using the 2D graph.

Abstract: The present disclosure is related to methods, systems and apparatus for performing electrophysiological measurements utilizing three or more electrodes attached to a patient. The system in various embodiments may include three or more electrodes attached to the patient and at least one analog-to-digital converter with external circuitry electrically coupled to the electrodes. The system may further include a microprocessor for driving the analog-to-digital conversion process, various inputs and variable frequency current outputs electrically coupled to the microprocessor for receiving signals from the electrodes and sending driven current signals to the electrodes.

Abstract: Systems and methods for determining an arrhythmia type are provided. A method may include: obtaining an electrocardiogram signal, obtaining a feature vector of the electrocardiogram signal, obtaining a trained prediction model, and determining an arrhythmia type of the electrocardiogram signal based on the trained prediction model and the feature vector. The feature vector includes a threshold crossing sample (TCSC) percent feature, an L-Z complexity feature, an empirical mode decomposition (EMD) complex number feature, a sample entropy feature, and a set of wavelet transform energy features.

Abstract: A subcutaneous cardiac defibrillation system implantable comprising a housing and a subcutaneous implantable lead comprising a proximal end connected to the housing and a distal free end. The subcutaneous implantable lead comprises at least one defibrillation electrode and at least three detection electrodes. The first detection electrode and the second detection electrode form a first dipole, and the third detection electrode and the first detection electrode, or the third detection electrode and the second detection electrode, or the housing and one of said detection electrodes, form a second dipole. The defibrillation electrode is positioned between the second detection electrode and the third detection electrode, the first dipole is positioned between the housing and the defibrillation electrode, the third electrode is positioned between the free distal end of the lead and the defibrillation electrode, and the length of the first dipole is shorter than the length of the second dipole.

Abstract: A system, including a first housing containing a speech processor that receives signals output by a microphone of the hearing prosthesis, a second housing removably connectable to the first housing at a bottom of the first housing, the bottom being at a first end of the first housing that is a wider end relative to a second end of the first housing opposite the first end and a first device removably connectable to the first housing when the second housing is disconnected from the first housing, wherein the first housing is part of a behind-the-ear (BTE) device, the second housing is part of a second device, and the system is a cochlear implant hearing prosthesis system.

Abstract: There is disclosed herein examples of systems and methods of processing captured heart sounds with frequency-dependent normalization. Based on an amount of attenuation of a first heart sound, a second heart sound can be normalized by modifying portions of the second heart sound by amounts determined based on frequencies of the portions. Accordingly, the systems and methods disclosed herein can result in different amounts of modification of different portions of the second heart sound based on the different frequencies of the portions.

Abstract: An electrocardiogram information dynamic monitoring method and dynamic monitoring system.

Abstract: An instantaneous heartbeat reliability evaluation apparatus includes: extraction means which extracts waveforms having a maximum value corresponding to depolarization of a heart in a biosignal of an examinee; first calculation means which calculates an interval between two waveforms neighboring in a time series; dividing means which divides a signal output from measurement means into signals of predetermined periods; second calculation means which calculates feature quantities of a potential of each divided signal; first evaluation means which evaluates whether a measurement state of each divided signal is normal or abnormal on the basis of feature quantities; and second evaluation means which evaluates measurement states of two neighboring extracted waveforms on the basis of an evaluation result obtained by the first evaluation means and evaluates reliability of a measurement state of the interval between the waveforms depending on a type of the evaluated measurement states of the waveforms.

Abstract: A muscle mass estimation method including acquiring a height of a living organism, acquiring an electrical resistance value measured for the living organism, and computing a muscle mass of the living organism using a calculation formula including a first variable including the height of the living organism and the electrical resistance value, and a second variable including the electrical resistance value.

Abstract: Systems and methods are described herein for evaluation and configuration cardiac therapy. The systems and methods may monitor electrical activity using a plurality of external electrodes and may utilize multiple-electrode cardiac metrics such as electrical heterogeneity information, single-electrode cardiac metrics, and vectorcardiographic metrics to determine and select one or more paced settings from a plurality of different paced settings.

Abstract: A system is provided for displaying heart graphic information relating to sources and source locations of a heart disorder to assist in evaluation of the heart disorder. A heart graphic display system provides an intra-cardiogram similarity (“ICS”) graphic and a source location (“SL”) graphic. The ICS graphic includes a grid with the x-axis and y-axis representing patient cycles of a patient cardiogram with the intersections of the patient cycle identifiers indicating similarity between the patient cycles. The SL graphic provides a representation of a heart with source locations indicated. The source locations are identified based on similarity of a patient cycle to library cycles of a library cardiogram of a library of cardiograms.

Abstract: In some examples, a medical device system includes a first implantable medical device. The first implantable medical device (IMD) may comprise circuitry configured to at least one of deliver a therapy to a patient or sense a physiological signal from the patient; generate stimulation deliverable to a patient; a first rechargeable power source; and a secondary coil coupled to the first rechargeable power source, the secondary coil configured to charge the first rechargeable power source via inductive coupling with a primary coil of an external charging device. The medical device system may comprise processing circuitry configured to control charging of the first rechargeable power source based on a charge state of a second rechargeable power source of a second IMD.

Abstract: A computer implemented method and system are described that identify one or more regions of the heart responsible for supporting or initiating abnormal heart rhythms. Electrogram data is used that has been recorded from a plurality of electrodes on multipolar cardiac catheters obtained from a corresponding series of sensing locations on the heart over a recording time period.

Abstract: This disclosure relates generally to detection of mild cognitive impairments in subjects. The method and system proposed provides a continuous/seamless monitoring platform for MCI detection in subjects by continuously monitoring routine activities of subjects (Activities of Daily Living (ADL)) in a smart environment using plurality of passive, unobtrusive, binary, unobtrusive non-intrusive sensors embedded in living infrastructure. The proposed method and system detects symptoms of MCI at the onset of the disease, while also addressing issue of sensor failures that causes gaps in the data. The collected sensor data is pre-processed in several stages which includes which includes pre-processing of sensor data, behavior deviation detection, and abnormality detection and so on. Further, the disclosure also proposes an autoencoder based technique, to reduce the dimension of the data to find personalized deviations in behavior of a subject which is used to detect if a subject could be a potential case of MCI.

Abstract: Long-term electrocardiographic and physiological monitoring over a period lasting up to several years in duration can be provided through a continuously-recording subcutaneous insertable cardiac monitor (ICM). The sensing circuitry and the physical layout of the electrodes are specifically optimized to capture electrical signals from the propagation of low amplitude, relatively low frequency content cardiac action potentials, particularly the P-waves that are generated during atrial activation. In general, the ICM is intended to be implanted centrally and positioned axially and slightly to either the left or right of the sternal midline in the parasternal region of the chest. Additionally, the ICM includes an ECG sensing circuit that measures raw cutaneous electrical signals and performs signal processing prior to outputting the processed signals for sampling and storage.

Abstract: The present invention includes an apparatus for transdermal treatments comprising: an openable enclosure for a subject in communication with three or more sources of treatment modalities selected from: a source of ozone; a source of steam, a source of CO2/Carbonic Acid; a source of Far Infrared; and a source of pulsed electromagnetic fields (PEMF), wherein each of the three or more sources is in communication with an interior of the openable enclosure to treat the subject transdermally.