Patents Examined by Sean A Frith
  • Patent number: 12263038
    Abstract: An elasticity imaging method, device, and storage medium are provided. The method includes: transmitting an ultrasound wave to a target tissue; receiving an ultrasound echo of the ultrasound wave returned from the target tissue; obtaining an interference characteristic information representing the degree of interference to the target tissue; and when the interference characteristic information does not meet a preset condition, stopping determining an elasticity image of the target tissue according to the ultrasound echo.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: April 1, 2025
    Assignees: Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen Mindray Scientific Co., Ltd.
    Inventors: Shuangshuang Li, Donghai Qin, Zebing Wang
  • Patent number: 12262959
    Abstract: The present invention relates to a method for determining the spatial position of objects, in particular medical objects. First position data is acquired that describes a spatial position of an object in a first coordinate system. First transformation data is acquired that transforms the object's position from the first coordinate system to a second coordinate system. Based on the foregoing data, second position data is acquired that specifies the spatial position of the object in the second coordinate system. Second transformation data is acquired that transforms the object's position from the second coordinate system to an inertial coordinate system. Based on the second position data and the second transformation data, inertial position data is determined that specifies a position of the object in the inertial coordinate system.
    Type: Grant
    Filed: August 31, 2023
    Date of Patent: April 1, 2025
    Assignee: Brainlab AG
    Inventors: Oliver Fleig, Timo Neubauer, Mario Schubert, Sabine Kling
  • Patent number: 12251189
    Abstract: The invention provides for a medical instrument (100, 300, 400, 500, 600) comprising a camera system (102, 102?, 102?) for imaging a portion (418) of a subject (108) reposing on a subject support (106). The medical instrument further comprises a display system (104) for rendering a position feedback indicator (130, 900). The display system is configured such that the position feedback indicator is visible to the subject when the subject is reposing on the subject support.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: March 18, 2025
    Assignee: Koninklijke Philips N.V.
    Inventors: Sascha Krueger, Christian Stehning, Peter Mazurkewitz
  • Patent number: 12246195
    Abstract: Systems and methods for treating target tissue include generating a priming sequence of sonication pulses for delivering acoustic energy to the target tissue; pausing generation of the sonication pulses for a delay interval; and generating a series of treatment sequences of sonication pulses for delivering acoustic energy to the target tissue, the treatment sequences having sonication intervals therebetween and the delay interval being larger than the largest sonication interval by a predetermined factor.
    Type: Grant
    Filed: October 12, 2020
    Date of Patent: March 11, 2025
    Assignee: INSIGHTEC, LTD.
    Inventors: Yoav Levy, Israel Schuster, Shahar Rinott
  • Patent number: 12245825
    Abstract: Systems and methods for ascertaining a position of an orthopedic element in space comprising: capturing a first and second images of an orthopedic element in different reference frames using a radiographic imaging technique, detecting spatial data defining anatomical landmarks on or in the orthopedic element using a deep learning network, applying a mask to the orthopedic element defined by an anatomical landmark, projecting the spatial data from the first image and the second image to define volume data, applying the deep learning network to the volume data to generate a reconstructed three-dimensional model of the orthopedic element; and mapping the three-dimensional model of the orthopedic element to the spatial data to determine the position of the three-dimensional model of the orthopedic element in three-dimensional space.
    Type: Grant
    Filed: September 28, 2022
    Date of Patent: March 11, 2025
    Assignee: MicroPort Orthopedics Holdings Inc.
    Inventors: Brian R. Harris, Jr., Fred W. Bowman
  • Patent number: 12228635
    Abstract: The invention provides for a medical instrument (100, 300, 400, 500) comprising a magnetic resonance imaging system (102). The medical instrument further comprises a subject support (120) with a support surface (121) configured for supporting at least a portion of the subject within an imaging zone (108). The subject support comprises a radar array (125) embedded below the support surface. The medical instrument further comprises a radar system (124) for acquiring a radar signal (144) from the subject. The medical instrument further comprises a motion detection system (122) configured for acquiring a movement signal (146).
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: February 18, 2025
    Assignee: Koninklijke Philips N.V.
    Inventors: Daniel Wirtz, Tim Nielsen, Christoph Leussler
  • Patent number: 12226185
    Abstract: A catheter-based imaging apparatus comprises a catheter having a proximal end and a distal end. An optical emitter is configured to emit optical excitation signals from a distal portion of the catheter. One or more ultrasound transducers are configured for: (a) transmission of acoustic excitation signals from the distal portion of the catheter; and (b) detection of ultrasound response signals from an object of interest at or near to the distal portion of the catheter at frequencies which include a lower receive frequency at least as low as 10 MHz and a higher receive frequency at least as high as 35 MHz. The one or more ultrasound transducers are thereby configured to detect response signals comprising photoacoustic response signals from the object of interest at the lower receive frequency and high resolution imaging signals from the object of interest at the higher receive frequency.
    Type: Grant
    Filed: October 18, 2023
    Date of Patent: February 18, 2025
    Assignee: Erasmus University Medical Center Rotterdam
    Inventors: Gijs Van Soest, Verya Daeichin, Antonius Franciscus Wilhelmus Van Der Steen
  • Patent number: 12220278
    Abstract: A medical device (10) for insertion into a patient is disclosed. The medical device (10) comprising an elongate body (12), the medical device terminating in a distal portion and further comprising a carrier (20) carrying an annular sensor arrangement (50), wherein the annular sensor arrangement is attached on a forward facing surface of the elongate body (12). Also disclosed is a system (100) including such a medical device (10).
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: February 11, 2025
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Arjen Van Der Horst, Roland Alexander Van De Molengraaf, Vincent Adrianus Henneken, Johannes Wilhelmus Weekamp, Maarten Petrus Joseph Kuenen, Sergei Y. Shulepov, Bruno Jean François Frackowiak
  • Patent number: 12213765
    Abstract: An illustrative optical measurement system includes a light source configured to emit light directed at a target, an array of photodetectors configured to detect photons of the light after the light is scattered by the target, and a processing unit configured to measure a noise level of a photodetector included in the array of photodetectors, the noise level comprising a dark count rate that measures a dark count divided by a time period, determine that the noise level meets a predetermined threshold comprising a dark count rate threshold, and prevent, based on the determining that the noise level meets the predetermined threshold, an output of the photodetector from being used in generating a histogram based on a temporal distribution of photons detected by the array of photodetectors, the preventing comprising switching the output to a monitoring circuit that monitors a characteristic of the optical measurement system separate from the photodetector.
    Type: Grant
    Filed: November 30, 2023
    Date of Patent: February 4, 2025
    Assignee: HI LLC
    Inventors: Sebastian Sorgenfrei, Ryan Field, Bruno Do Valle, Isai Olvera, Jacob Dahle, Husam Katnani
  • Patent number: 12214223
    Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation that include applying energy (e.g., ultrasound energy) into an internal tissue to cause tissue displacement and identifying that the tissue displacement has occurred. In one embodiment, the presence of tissue displacement is associated with a desired therapeutic or physiological outcome, such as a change in a molecule of interest.
    Type: Grant
    Filed: March 23, 2023
    Date of Patent: February 4, 2025
    Assignee: GE Precision Healthcare LLC
    Inventors: Jeffrey Michael Ashe, Christopher Michael Puleo, Victoria Eugenia Cotero, Ying Fan, Kirk Dennis Wallace, John Frederick Graf
  • Patent number: 12207901
    Abstract: A system for generating and detecting transient vapor nanobubbles in a fluid from a patient can include a micro-fluidic device to receive a flow of the fluid from the patient, a laser pulse source to provide a laser pulse to the flow of the fluid from a first side of the micro-fluidic device, a probe light source to provide a probe light to the flow from the first side of the micro-fluidic device, and a photodetector located at a second side of the micro-fluidic device opposite the first side. The photodetector can detect scattered, reflected, and/or deflected probe light and output a nanobubble signal including characteristics of optical scattering, reflecting, and/or deflecting by the transient vapor nanobubble.
    Type: Grant
    Filed: December 19, 2023
    Date of Patent: January 28, 2025
    Assignee: Masimo Corporation
    Inventors: Dmitri O. Lapotko, Katsiaryna Hleb, Mohamed K. Diab
  • Patent number: 12193803
    Abstract: The present disclosure is related to systems and methods for magnetic resonance imaging (MRI). The method includes obtaining a plurality of target sets of k-space data by filling target MR signals acquired by a plurality of coils of an MRI device into k-space along a corkscrew trajectory. The method includes obtaining a coil sensitivity of each of the plurality of coils. The method includes obtaining a point spread function corresponding to the corkscrew trajectory. The method includes generating a target image based on an objective function.
    Type: Grant
    Filed: June 24, 2021
    Date of Patent: January 14, 2025
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Jingyuan Lyu, Yongquan Ye
  • Patent number: 12196824
    Abstract: A medical system is provided with: a medical device that is inserted inside a living body; a distal end electrode that is disposed at a distal end of the medical device, and passes a high frequency to the living body from inside the living body; a magnetic sensor that is disposed outside the living body, and detects a magnetic field generated by the high frequency that has been passed from the distal end electrode to the living body; and an image generation portion that generates an internal image of the living body using magnetic field information output from the magnetic sensor.
    Type: Grant
    Filed: December 9, 2022
    Date of Patent: January 14, 2025
    Assignee: ASAHI INTECC CO., LTD.
    Inventor: Fumiyoshi Oshima
  • Patent number: 12186063
    Abstract: The present invention is directed to a system and method for determining blood volume in a subject. Blood volume is an important hemodynamic parameter for monitoring many disorders, such as stoke and cancer. Current MRI techniques for quantification of absolute blood volume for such clinical applications all require injecting exogenous contrast agents. To reduce associated safety risks and cost, the present invention is directed to a non-contrast-enhanced MRI method for blood volume mapping on MRI. The technique of the present invention employs velocity-selective (VS) pulse trains in paired control and label modules for separating vascular signal by subtraction. The Fourier-transform based VS saturation pulse train (FT-VSS) of the present invention has improved performance over conventional VS pulse trains for the blood volume measurement.
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: January 7, 2025
    Assignee: The Johns Hopkins University
    Inventor: Qin Qin
  • Patent number: 12186067
    Abstract: A method may include obtaining a plurality of imaging signals collected by applying a wave encoding gradient to a region of interest (ROI) of a subject. The method may also include obtaining a plurality of auxiliary signals associated with the ROI. The method may also include obtaining a point spread function corresponding to the wave encoding gradient. The method may also include determining, based on the plurality of auxiliary signals, temporal information relating to at least one temporal dimension of the ROI. The method may also include determining, based on the plurality of auxiliary signals, the plurality of imaging signals, and the point spread function, spatial information relating to at least one spatial dimension of the ROI. The method may also include generating at least one target image of the ROI based on the temporal information and the spatial information.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: January 7, 2025
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Jingyuan Lyu, Qi Liu, Yongquan Ye, Jian Xu, Zhongqi Zhang
  • Patent number: 12178890
    Abstract: Described herein is a method for detecting changes in blood flow in a tissue portion and/or body portion of an individual. The method can be used to detect any sort of pathology, trauma or insult which results in blood flow change. Specifically, this method uses hyperpolarized 129Xe MRI to detect xenon perfusion changes in tissues such as brain tissue that corresponds to changes in blood flow, for example, changes caused by functional activities of the brain or regions of the body where blood flow may be compromised.
    Type: Grant
    Filed: January 20, 2020
    Date of Patent: December 31, 2024
    Assignee: Lakehead University
    Inventors: Mitchell Albert, Francis Hane, Yurii Shepelytskyi, Tao Li
  • Patent number: 12161455
    Abstract: The invention provides for a medical imaging system (100, 300, 500) comprising a processor (104). Machine executable instructions cause the processor to: receive (200) magnetic resonance data (120) comprising discrete data portions (612) that are rotated in k-space; bin (202) the discrete data portions into predetermined motion bins (122) using a motion signal value; reconstruct (204) a reference image (124) for each of the predetermined motion bins; construct (206) a motion transform (126) between the reference images; bin (208) a chosen group (610) of the discrete data portions into a chosen time bin (128). Generate an enhanced image (130) for the chosen time bin using the chosen group fo the discrete data portions and the motion transform of each of the chosen group to correct the discrete data portions.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: December 10, 2024
    Assignee: Koninklijke Philips N.V.
    Inventors: Tim Nielsen, Jan Hendrik Wuelbern
  • Patent number: 12161442
    Abstract: According to an aspect, a method for determining an augmented vital sign, such as heart rate or heart rate variability, includes obtaining signals from a patient when the patient is both active and inactive. An activity signal is generated from the first signal, and a physiological signal is generated from the second signal. An activity weight factor is calculated from the activity signal, and a vital sign signal is calculated from the physiological signal. A mapping from the activity signal to the vital sign aids the determination of the vital sign through a motion period. The augmented vital sign is a result of the combination of first and second values, including the product of the activity weight factor and an activity derived vital sign, and the product of the vital sign signal and the activity weight factor less than one.
    Type: Grant
    Filed: September 18, 2020
    Date of Patent: December 10, 2024
    Assignee: COVIDIEN LP
    Inventors: Philip C. Smit, Paul S. Addison
  • Patent number: 12150720
    Abstract: The present invention relates to a surgical microscope with a field of view and comprising an optical imaging system which images an inspection area which is at least partially located in the field of view, and to a method for a gesture control of a surgical microscope having an optical imaging system. The surgical microscope further comprises a gesture detection unit for detection of a movement of a surgical instrument, the gesture detection unit having a detection zone which is located between the inspection area and the optical imaging system and is spaced apart from the inspection area, and the gesture detection unit being configured to output a control signal to the optical imaging system depending on the movement of the surgical instrument in the detection zone, the optical imaging system being configured to alter its state depending on the control signal.
    Type: Grant
    Filed: July 17, 2023
    Date of Patent: November 26, 2024
    Assignee: LEICA INSTRUMENTS (SINGAPORE) PTE. LTD.
    Inventor: George Themelis
  • Patent number: 12140655
    Abstract: A dynamic magnetic resonance angiography, MRA, method, comprising: acquiring, by an MR scanning device, a multi-contrast magnetic resonance, MR, sequence of a portion of a body; identifying, by a processing circuit, blood vessels of the portion by identifying blood of the portion based on predetermined characteristic of blood and the multi-contrast MR sequence; generating, by the processing circuit, a first MRA image frame and a second MRA image frame, based on the multi-contrast MR sequence, respectively visualising a first part and a second part of the identified blood vessels; generating, by the processing circuit, a dynamic MRA image for visualising a dynamic blood flow through a part of the portion, based on the first and second MRA image frame.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: November 12, 2024
    Assignee: SYNTHETICMR AB (PUBL)
    Inventor: Marcel Warntjes