Abstract: A catheter-based imaging apparatus comprises a catheter having a proximal end and a distal end. An optical emitter is configured to emit optical excitation signals from a distal portion of the catheter. One or more ultrasound transducers are configured for: (a) transmission of acoustic excitation signals from the distal portion of the catheter; and (b) detection of ultrasound response signals from an object of interest at or near to the distal portion of the catheter at frequencies which include a lower receive frequency at least as low as 10 MHz and a higher receive frequency at least as high as 35 MHz. The one or more ultrasound transducers are thereby configured to detect response signals comprising photoacoustic response signals from the object of interest at the lower receive frequency and high resolution imaging signals from the object of interest at the higher receive frequency.

Abstract: A system is provided in the present disclosure. The system may acquire a first set of echo signals and a second set of echo signals relating to a subject. The first and the second set may be generated by using an MR scanner to execute a first acquisition and a second acquisition on the subject, respectively. The first acquisition may include at least a first repetition and a second repetition with different repetition times. Each of the first and second repetitions may have a first flip angle. The second acquisition may include at least a third repetition and a fourth repetition with different repetition times. Each of the third repetition and the fourth repetition may have a second flip angle different from the first flip angle. The system may also perform a measurement on the subject based on at least one of the first set or the second set.

Abstract: To suppress the image quality deterioration due to respiratory motion and changes thereof, and improve the data acquisition rate. An MRI device according to the present invention repeats a main measurement in a predetermined unit, and performs a navigation measurement to acquire one or a plurality of the navigator echoes between the measurements in the temporally adjacent two predetermined units, and performs determination as to whether to continue or discontinue the main measurement and determination as to whether to discard immediately prior measurement data. In the determination, at least two navigator echoes are used, and by using a position of a site to be monitored by the navigation measurement and a displacement width serving as a reference of the displacement stability, whether the position and the displacement width satisfy a reference displacement and a reference displacement width, which have been obtained in advance, is determined.

Abstract: A device and a method, which is individual to a patient, treat malignant diseases by using selectively acting tumor-destructive mechanical pulses (TMI). The tumor-destructive pulse shapes are determined using physical cell properties, which are individual to each patient. The device is controlled in such that lethal pulse fields are applied in the tumor area.

Abstract: An ultrasound signal processing device performs transmission events by an ultrasound probe having transducer elements, generates a sub-frame acoustic line signal for each transmission event based on reflected ultrasound, and synthesizes sub-frame acoustic line signals to generate a frame acoustic line signal. A transmitter causes the ultrasound probe to transmit ultrasound beams to an ultrasound main irradiation area. A receiver generates receive signals for the transducer elements. A delay-and-sum calculator sets a target area in the ultrasound main irradiation area, and performs delay-and-sum calculation with respect to the receive signals from measurement points in the target area to generate a sub-frame acoustic line signal. The target area has, in a depth range shallower than a focal point, a width in the transducer element array direction that decreases as the depth decreases. A synthesizer synthesizes sub-frame acoustic line signals.

Abstract: A control device including: a breast thickness acquisition unit that acquires a thickness of a breast in a pressed state by a pressing member; a depth information acquisition unit that, in a case where an ultrasound image of the breast in the pressed state is captured, acquires depth information indicating a depth to which imaging by an ultrasonography apparatus which captures the ultrasound image is possible; a deriving unit that derives imaging information indicating whether or not capture of an ultrasound image having predetermined accuracy or higher is possible by the ultrasonography apparatus on the basis of the thickness of the breast acquired by the breast thickness acquisition unit and the depth information acquired by the depth information acquisition unit; and an output unit that outputs the imaging information derived by the deriving unit.

Abstract: The present invention relates to a surgical microscope with a field of view and comprising an optical imaging system which images an inspection area which is at least partially located in the field of view, and to a method for a gesture control of a surgical microscope having an optical imaging system. The surgical microscope further comprises a gesture detection unit for detection of a movement of a surgical instrument, the gesture detection unit having a detection zone which is located between the inspection area and the optical imaging system and is spaced apart from the inspection area, and the gesture detection unit being configured to output a control signal to the optical imaging system depending on the movement of the surgical instrument in the detection zone, the optical imaging system being configured to alter its state depending on the control signal.

Abstract: A compression plate of a mammography apparatus has an upper surface which is irradiated with radiation, a lower surface which is opposite to the upper surface and comes into contact with the breast, and a surface which is parallel to the upper surface between the upper surface and the lower surface. In the compression plate, a compression plate scale for identifying an in-plane position of each surface is given to any one of the surfaces. A first display control unit of a console performs control to display a radiographic image captured by the mammography apparatus on a display unit. A second display control unit of the console performs control to display an image scale which indicates a position on the radiographic image corresponding to the in-plane position of the compression plate on the radiographic image displayed on the display unit.

Abstract: The invention provides a fluid analysis apparatus, a method for operating a fluid analysis apparatus, and a fluid analysis program that display a flow velocity vector such that the tendency of a fluid flow is easily checked. A representative two-dimensional flow velocity vector representing a plurality of two-dimensional flow velocity vectors obtained by projecting three-dimensional flow velocity vectors of a plurality of voxels that overlap each other in a projection direction of a projection plane to the projection plane is acquired from three-dimensional volume data that has information of the three-dimensional flow velocity vector indicating the flow velocity of a fluid in an anatomical structure for each voxel and is displayed.

Abstract: A mammography apparatus includes a compression control unit that, in a case in which continuous imaging that captures a radiographic image of the breast compressed by a compression plate and then captures an ultrasound image of the breast while maintaining the compressed state is performed, performs control to set a force of the compression plate compressing the breast to a first force in the capture of the radiographic image and to change the force of the compression plate compressing the breast from the first force to a second force lower than the first force in the capture of the ultrasound image.

Abstract: K-space data obtained from a magnetic resonance imaging scan where motion was detected is split into two parts in accordance with the timing of the motion to produce first and second sets of k-space data corresponding to different poses. Sub-images are reconstructed from the k first and second sets of k-space data, which are used as inputs to a deep neural network which transforms them into a motion-corrected image.

Abstract: An apparatus includes a balloon adapted to be placed adjacent a calcified region of a body. The balloon is inflatable with a liquid. The apparatus further includes a shock wave generator within the balloon that produces shock waves that propagate through the liquid for impinging upon the calcified region adjacent the balloon. The shock wave generator includes a plurality of shock wave sources distributed within the balloon.

Abstract: An ultrasound observation apparatus includes: a B-mode image generation unit; a region selection information input unit; a region-of-interest setting unit configured to set a region of interest of an ultrasound image to be subjected to processing suitable for an operation mode selected, in accordance with the input, from a plurality of operation modes for detecting a selected one of a plurality of pieces of characteristic biological information, by calculation using a region-of-interest setting method previously associated with the operation mode, based on a desired region selected in the region selection information; and a mode image composition unit configured to generate a mode composite image in which an operation mode image presented in two dimensions additional information obtained by performing processing suitable for the operation mode selected in accordance with the input on the region of interest is superimposed on a B-mode image generated by the B-mode image generation unit.

Abstract: An ultrasound-assisted wound cleanser in the form of a handheld device includes an integrated vibration motor, an integrated ultrasound generator, an integrated energy source for the vibration motor and the ultrasound generator, and a replaceable cleansing attachment which can be driven by the vibration motor for abrasively removing wound coatings. The cleansing attachment has an acoustic transducer which is designed to convert the electric oscillations generated by the ultrasound generator into sound waves, a device for reinforcing and/or distributing and/or transferring the ultrasound waves, and bristles and/or lamellas for the abrasive removal. Further, a method for cleansing wounds includes moving a cleansing attachment with bristles for abrasively removing wound coatings by a vibration motor. The cleansing attachment is oscillated by an ultrasound generator, and the oscillations for supporting the removal of wound coatings are transmitted into the wound via a transmission medium.

Abstract: A method, device, and system for evaluating a vessel of a patient, and in particular the hemodynamic impact of a stenosis within the vessel of a patient. Proximal and distal pressure measurements are made using first and second instrument while the first instrument is moved longitudinally in the vessel and the second instrument remains in a fixed position. A series of pressure ratio values are calculated, and a pressure ratio curve is generated. The pressure ratio curve may be output to a display. One or more stepped change in the pressure ratio curve are identified using an Automatic Step Detection algorithm. An image is obtained showing the position of the first instrument within the vessel that corresponds to the identified stepped change. The image is registered to the identified stepped change in the pressure ratio curve. The image may be output to the display.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for performing EEG source localization. One of the methods includes obtaining brain data comprising: EEG data comprising respective channel data corresponding to each of a plurality of electrodes of an EEG sensor, and fMRI data comprising respective voxel data corresponding to each of a plurality of voxels; identifying, in a three-dimensional coordinate system, a respective location for each electrode; generating, using the respective identified locations of each electrode, data representing a location in the three-dimensional coordinate system of each voxel; determining, for each electrode, a region of interest in the three-dimensional coordinate system; and identifying, for each electrode, one or more corresponding parcellations in the brain of the subject, wherein each parcellation that corresponds to an electrode at least partially overlaps with the region of interest of the electrode.

Abstract: A method and system for deep learning based cardiac electrophysiological model personalization is disclosed. Electrophysiological measurements of a patient, such as an ECG trace, are received. A computational cardiac electrophysiology model is personalized by calculating patient-specific values for a parameter of the computational cardiac electrophysiology model based at least on the electrophysiological measurements of the patient using a trained deep neural network (DNN). The parameter of the computational cardiac electrophysiology model corresponds to a spatially varying electrical cardiac tissue property.

Abstract: A 3D model of AC electrical conductivity (at a given frequency) of an anatomic volume can be created by obtaining two MRI images of the anatomic volume, where the two images have different repetition times. Then, for each voxel in the anatomic volume, a ratio IR of the intensity of the corresponding voxels in the two MRI images is calculated. This calculated IR is then mapped into a corresponding voxel of a 3D model of AC electrical conductivity at the given frequency. The given frequency is below 1 MHz (e.g., 200 kHz). In some embodiments, the 3D model of AC electrical conductivity at the given frequency is used to determine the positions for the electrodes in TTFields (Tumor Treating Fields) treatment.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation that include applying energy (e.g., ultrasound energy) into an internal tissue to cause tissue displacement and identifying that the tissue displacement has occurred. In one embodiment, the presence of tissue displacement is associated with a desired therapeutic or physiological outcome, such as a change in a molecule of interest.

Abstract: A method is disclosed for correcting the mismatch between computed tomography (CT) scan and positron emission tomography (PET) scan modalities caused by patient respiration by selecting PET image slices aligned with the phase and amplitude in which the CT was acquired PET image slices so they are aligned with the phase and amplitude in which the CT scan was acquired.