Abstract: The present disclosure relates to a system, method, and computer program product for computer-aided detection (CAD) of suspicious lesions in digital breast specimen radiographs, wherein single-view feature vectors from a first digital radiograph of the breast specimen are processed in a classification algorithm along with information computed from a plurality of related digital specimen radiographs to assign an overall probability of suspiciousness to potentially suspicious lesions in the first digital breast specimen radiography. In one embodiment, a greater probability of suspiciousness is determined where there are similar corresponding lesions in the first digital breast specimen radiography and in an alternate digital breast specimen radiography view of the same breast specimen.

Abstract: Embodiments of the present disclosure relate to techniques for facilitating personalized neuromodulation treatment protocols. In one embodiment, a predetermined treatment position of an energy application device is used to guide future treatments for the patient. In one embodiment, a position of the energy application device relative to the predetermined treatment position is determined. In one embodiment, a total dose of ultrasound energy applied to the region of interest is determined.

Abstract: Methods and systems for x-ray and fluoroscopic image capture and, in particular, to a versatile, multimode imaging system incorporating a hand-held x-ray emitter operative to capture digital or thermal images of a target; a stage operative to capture static x-ray and dynamic fluoroscopic images of the target; a system for the tracking and positioning of the x-ray emission; a device to automatically limit the field of the x-ray emission; and methods of use. Automatic systems to determine the correct technique factors for fluoroscopic and radiographic capture, ex-ante.

Abstract: The invention presents an apparatus (6) for characterization of a condition of a vessel (12) wall of a living being (2). The relationship between temporal blood pressure (621) and blood flow (622) measurements of pulsatile blood motion within the vessel (12) is an indication of the health of the vessel (12) wall. Furthermore, the invention discloses a system (1) comprising the apparatus (6), and a method (100) of characterizing the condition of vessel (12) walls.

Abstract: Exemplary methods, apparatus, and systems are disclosed for automated registration and motion compensation of patient-mounted needle guide medical devices using fiducial markers, and processing algorithms where a re-registration step is provided. These methods, apparati, and systems adaptively compensate for the displacement of the medical device and/or target location due to the patient movement or internal organ motion.

Abstract: Devices, systems, and methods are disclosed for use in tomographic ultrasound imaging, large aperture ultrasound imaging and therapeutic ultrasound that provide for coupling acoustic signal transducers to body structures for transmitting and receiving acoustic signals. The acoustic signal transmission couplants can conform to the receiving medium (e.g., skin) of the subject such that there is an acoustic impedance matching between the receiving medium and the transducer. In one aspect, an acoustic coupling medium includes a hydrogel including polymerizable material that form a network structured to entrap an aqueous fluid inside the hydrogel.

Abstract: A medical image display apparatus for displaying medical images of a lung on a screen includes a network interface receiving positional information of a navigation instrument from a position sensor of the navigation instrument, a video stream from an optical sensor of the navigation instrument, and medical images from an imaging device, a memory storing a plurality of medical images and instructions, a processor executing the instructions, and a display dynamically displaying images on the screen. The instructions, when executed by the processor, cause the medical image display apparatus to determine whether status information indicates a pathway reviewing mode, a target management mode, or a navigation mode. The instructions, when executed by the processor, further cause the display to dynamically select and update images, which are displayed on the screen, among the plurality of medical images based on the positional information of the navigation instrument and status information.

Abstract: A method for assisting in navigation of a medical instrument such as a catheter inside a hollow body such as a vascular system based on a dataset provided by a sensor device of the medical instrument is provided The method includes determining, by a control device, an internal extent of the hollow body based on the provided dataset and determining, by the control device, a navigation path for an impending movement of the medical instrument through the hollow body based on the determined internal extent. The control device is able to generate a control signal that describes a movement along the navigation path.

Abstract: A measurement sensor package and a measurement sensor reduce susceptibility to noise and enable highly accurate measurement. A measurement sensor package (1) includes a substrate (2), a lid (3), and a ground conductor layer (4). The substrate (2) contains a light emitter and a light receiver, and includes a substrate body (20), a plurality of ground via conductors (21), an frame-shaped ground conductor layer (22), signal wiring conductors (23), and an external connection terminal (24). The ground via conductors (21) are connectable to a ground potential, and are located outward from a first recess (20a) and a second recess (20b) included in the substrate body (20) in a plan view.

Abstract: Devices, systems, and methods for monitoring and determining characteristics of wounds on a subject are disclosed. A monitoring device includes an imaging component and a computing device communicatively coupled to the imaging component. The imaging component includes a light emitting component that emits light at a calibrated wavelength, a laser emitting device, and an imaging device. The computing device directs the light emitting component to emit the light at the calibrated wavelength, directs the imaging component to cause the laser emitting device to emit a laser projection toward the wound, receives, from the imaging component, image data captured by the imaging device, determines, from the image data, the characteristics of the wound, and scores the wound based on the characteristics of the wound to obtain a wound score. The characteristics include one or more of a size of the wound, a type of tissue, and an amount of exudate.

Abstract: A system and method for navigating to a target site in a patient is provided. The system includes an extended working channel and a tool usable with an electromagnetic navigation system. In particular, the extended working channel and the tool contain an electromagnetic sensor configured to provide location information within a patient of the extended working channel and the tool to the electromagnetic navigation system. The distance from the tool and the target site can then be determined and displayed to a clinician on a display device.

Abstract: Handheld ultrasound imaging devices for identification of target regions are generally described. Medical ultrasound is a popular medical imaging modality primarily used for diagnostic imaging of soft tissue but also for interventional procedures such as guidance of a needle or catheter placement. Examples include diagnostic imaging of organs, such cardiac or liver structures. Common interventional procedures that rely on ultrasound guidance are central line placement and guidance of nerve blocks, both of which are high volume procedures in certain hospital settings such as the intensive care unit (ICU). Handheld ultrasound imaging devices with integral display screens and improve portability are described, along with systems and methods for orienting displayed ultrasound images so as to improve their usefulness in guiding interventional procedures.

Abstract: A photoacoustic probe which prevents foreign substances from entering and of which a portion of a light emitting unit to be easily damaged can be replaced is provided. An acoustic wave detector 24 detects acoustic waves. First and second light guide members 21 and 23, which form the light emitting unit, are arranged in series in a traveling direction of light. A frame body 11 holds the first light guide members 21, the second light guide members 23, and the acoustic wave detector 24. The first light guide members 21, is positioned close to a subject, is undetachably fixed to the frame body 11. Meanwhile, the second light guide members 23, which is positioned close to a light source, is detachably fixed to the frame body 11.

Abstract: Presented herein are systems and methods for tomographic imaging that provide for rapid illumination of multiple excitation locations across a large field of view by one or more beams of excitation light from one or more excitation sources. The approaches described herein utilize a galvanometer optical scanner to scan a beam of excitation light through a plurality of locations across a scan region corresponding to the field of view to be imaged. In certain embodiments, the systems and methods described herein utilize beams of excitation light with specifically tailored shapes to maintain small spot sizes across the large scan region. The ability to scan over a large region while still maintaining small spot sizes provided by the approaches described herein allows for accurate, high-resolution tomographic imaging of large or multiple subjects, thereby expanding the capabilities of tomographic imaging systems.

Abstract: An ultrasonically actuated medical implement is used in improving medical interventions and in certain instances to the generation of image data, in particular data acquired during a medical intervention or procedure. The medical implement employs a piezoelectric element which causes reciprocation between first and second mass assemblies in order to ultrasonically actuate a probe member and improve the visibility of the probe member to imaging methods. The invention also concerns the visibility of structures in target regions to be imaged and how this may be enhanced using the medical implement of the invention.

Abstract: A method and device is taught to improve the appearance of cellulite by combining mild exfoliation of the skin, various wavelengths of low level light, ultrasound, and a vacuum or suction. The device is intended to increase the metabolic rate of the fat cells and reduce their size, while increasing the extensibility or length of the septae. Such increased activity will promote blood flow to the affected area thereby increasing cell nutrients and removing cellular exudates while stimulating the growth of new collagen thereby alleviating the cellulite.

Abstract: The invention addresses the problem of correctly positioning a catheter and reducing radiation doses. It relates to an X-ray imaging system (1) for a robotic catheter, comprising said catheter (3), and a processing unit (5) for receiving X-ray images of a patient environment (15). By being adapted to receive one or more auxiliary information items and using said information for determining the catheter position, the processing unit does not entirely have to rely on a large number of scanned image data, thus helping to reduce radiation while correctly delivering the catheter position as a function of as few as a single image, preferably 2D, and said one auxiliary information items. Further, said processing unit allows for at least one of rendering an image and provide said image to a visualization device (21), and providing feedback, e.g. steering commands, to said robotic catheter.

Abstract: A method for determining a respiratory condition or for assessing the efficacy of a treatment for a respiratory condition or for optimizing a treatment protocol for a respiratory condition in a subject comprising the steps of: a) obtaining image data concerning two or more three-dimensional images of the subject's respiratory system, which images have been previously acquired during an assessment period; b) calculating a specific three-dimensional structural model of the subject's respiratory system for each of the two or more three-dimensional images of step a); c) comparing the three-dimensional structural models of step b) with each other to determine a respiratory condition or to assess the efficacy of a treatment for a respiratory condition or to optimize a treatment protocol for a respiratory condition.

Abstract: A field generator includes multiple planar coils that are arranged in a single plane. At least two of the coils are non-concentric and are wound around respective axes that are not parallel with one another, so as to generate respective magnetic fields that are not parallel with one another.

Abstract: MRI interference with a concurrently operated system may be reduced or corrected by subtracting the MRI interference from signals measured using the concurrently operated system. Various approaches for performing MRI of an anatomic region in conjunction with a radio-frequency-sensitive (RF-sensitive) measurement of the region using the concurrently operated system include the steps of simultaneously performing an MR scan sequence including MR pulses and the RF-sensitive measurements; recording the RF-sensitive measurements as they are made; detecting intervals during the MR scan sequence when an RF level is sufficient to interfere with the RF-sensitive measurements; and retaining only the RF-sensitive measurements performed outside the detected intervals.