Abstract: Apparatus and methods are provided to concentrate energy delivery in non-superficial target tissue within a trigone region of a human bladder wall to modulate bladder function.

Abstract: A method of automatically assigning foot pedals of a robotic surgical system to surgical instruments of a surgical robot of the robotic surgical system includes: receiving a signal that a first electrosurgical pedal is actuated; determining a number of electrosurgical instruments connected to the surgical robot in response to actuation of the first electrosurgical foot pedal; assigning the first electrosurgical foot pedal to a first electrosurgical instrument connected to the surgical robot after the first electrosurgical foot pedal is actuated; and delivering electrosurgical energy to the first electrosurgical instrument in response to actuation of the first electrosurgical foot pedal after assigning the first electrosurgical foot pedal to the first electrosurgical instrument.

Abstract: Thermal therapy systems, devices, and methods of using the same disclosed. A localized hypothermia of the pancreas with a delivery and placement procedure in the stomach of a patient comprising a cooling balloon system is disclosed that can be used for the treatment of pancreatitis in a patient. The cooling balloon system can have mechanisms for affecting the pancreas without impacting or inducing hypothermia in the patient in a systemic fashion. The localized hypothermia system can have a simplified delivery system and can be intended to reduce patient discomfort while reducing the metabolic activity of the inflamed pancreas of the patient.

Abstract: A subcutaneously implantable device includes a housing, a clip attached to the housing, and an electrode. The clip is configured to move between an open position and a closed position to increase or decrease an opening between the housing and the clip to anchor the device to a muscle, a bone, and/or a first tissue. The electrode is configured to contact an organ, a nerve, the first tissue, and/or a second tissue. Circuitry in the housing is in electrical communication with the electrode and is configured to provide monitoring, therapeutic, and/or diagnostic capabilities with respect to the organ, the nerve, the first tissue, and/or the second tissue.

Abstract: An apparatus includes a shaft assembly. A sliding electrical coupling provides electrical continuity between components of the shaft while permitting movement of a second shaft component relative to a first shaft component at the joint. An end effector is positioned at a distal end of the shaft assembly and is operable to engage tissue of a patient. A sensor is positioned adjacent to the joint and is configured to measure a joint parameter indicating a state of the sliding electrical coupling. The sensor transmits a first signal indicative of the measured joint parameter to a control module. The control module determines whether the measured joint parameter exceeds a maximum deviation from a predetermined value. When the measured joint parameter exceeds a maximum deviation from a predetermined value, the control module initiates a responsive action.

Abstract: Surgical systems are disclosed. Surgical systems can include evacuation systems for evacuating smoke, fluid, and/or particulates from a surgical site. A surgical evacuation system can be intelligent and may include one or more sensors for detecting one or more properties of the surgical system, evacuation system, surgical procedure, surgical site, and/or patient tissue, for example.

Abstract: Systems and methods for manipulating the temperature of a surface are described. Described embodiments include thermal adjustment devices that may include a heatsink and that are operated in two or more modes of operation to apply a desired temperature to a user. In one operating mode the thermal adjustment device may apply a first temperature to an underlying surface while generating heat at a rate faster than the heatsink's heat dissipation rate. The thermal adjustment device may then apply a second temperature to reduce the rate of heat generation to be less than the heatsink's heat dissipation rate. These modes of operation may be applied cyclically to permit continuous operation of the thermal adjustment device. In some embodiments, the temperature profile applied when changing between the modes of operation may be selected such that the user experiences either a reduced, or substantially, neutral thermal sensation.

Abstract: An improved system described herein equipped with one or more Pulsed Field Electroporation (PFE) electrodes configured to cause localized and targeted PFE output at the targeted tissue, for example, in an ear, nose, or throat.

Abstract: An endoscope hybrid knife includes: a handle part having a hollow portion and an opening; first and second handle sliders coupled to the outer peripheral surface of the handle part so as to be slidable forwards and backwards in the longitudinal direction; a pipe disposed in the hollow portion of the handle part, and connected to the first handle slider; a second knife disposed to pass through the pipe, and connected to the second handle slider; a fluid injection part, which is coupled to one end of the handle part for injecting fluid therein; an inner tube which is connected to one end of the fluid injection part; a first knife coupled to the end of the pipe; and an insulating tip coupled to the end of the first knife, wherein the first knife and the second knife are slidable independently of each other.

Abstract: A sub-microsecond pulsed electric field generator is disclosed. The field generator includes a controller, which generates a power supply control signal and generates a pulse generator control signal, and a power supply, which receives the power supply control signal and generates one or more power voltages based on the received power supply control signal. The field generator also includes a pulse generator which receives the power voltages and the pulse generator control signal, and generates one or more pulses based on the power voltages and based on the pulse generator control signal. In some embodiments, the controller receives feedback signals representing a value of a characteristic of or a result of the pulses and generates at least one of the power supply control signal and the pulse generator control signal based on the received feedback signals.

Abstract: A pulse generator discharge circuit is disclosed. The circuit includes one or more discharge stages, each discharge stage including a plurality of control input terminals. The circuit also includes first and second discharge terminals, and a plurality of serially connected switches electrically connected between the first and second discharge terminals, where a conductive state of each of the switches is controlled by a control signal. The circuit also includes a plurality of inductive elements configured to generate the control signals for the serially connected switches, where each inductive element is configured to generate a control signal for one of the serially connected switches in response to one or more input signals at one or more of the control input terminals, and where each of the serially connected switches is configured to receive a control signal from a respective one of the inductive elements.

Abstract: Methods and devices for performing ablation using time multiplexed waveforms are disclosed. The increased efficacy of monophasic waveforms is combined with the reduced side effects of biphasic waveforms by distributing components of the waveform across over a broader time interval than that typically used in a conventional biphasic waveform. Charge balancing occurs upon completion of therapy delivery within a time period that avoids muscle stimulation, while allowing unbalanced waveforms to be delivered during stimulation.

Abstract: Methods and systems are disclosed for removing a tattoo from a subject's skin by application of a cold plasma that is delivered via a liquid-gas mixture. The plasma can be delivered in the form of gas bubbles, in which at least a portion of gas is in the form of a plasma.

Abstract: A system and apparatus for automatic smoke evacuation using an RF sensor. The system and apparatus utilizes an RF sensor for automatic activation of an evacuator that evacuates smoke and/or debris during the use of any electrosurgical instrument or surgical instrument that is capable of generating smoke and/or debris and capable of producing a radiofrequency during its operation. Exemplary embodiments of the system and apparatus for automatic smoke evacuation include both wired and wireless embodiments.

Abstract: A jet impingement cooling apparatus is provided including a housing having a surface to be directed at a treatment area, an optically transparent region on the surface of the housing through which electromagnetic radiation (EMR) from a source can be directed from the housing to the treatment area, and at least one opening on the surface of the housing through which a fluid flow can be directed to the treatment area to maintain the treatment area at a therapeutically acceptable temperature range while avoiding interference with the EMR being directed at the treatment area.

Abstract: Systems and methods for evaluating neuromodulation via hemodynamic responses are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a neuromodulation catheter comprising an elongated shaft having a distal portion, and a plurality of electrodes spaced along a distal portion. The system can further include a controller communicatively coupled to the electrodes. The controller can be configured to apply first and second stimuli at and/or proximate to a target site within a blood vessel before and after delivering neuromodulation energy to the target site, and detect, via at least one of the electrodes, vessel impedance resulting from the first and second stimuli to determine a baseline impedance and a post-neuromodulation impedance. The controller can further be configured to assess the efficacy of the neuromodulation based, at least in part, on a comparison of the baseline impedance and the post-neuromodulation impedance.

Abstract: An apparatus capable of generating high power microwave frequency pulses for use with an electrosurgical device. The apparatus may be used for coagulating or ablating biological tissue. The apparatus includes an amplifier line-up comprising: a microwave signal generator for generating microwave radiation; a modulator arranged to pulse the microwave radiation; and an amplifier module arranged to increase the power of pulses of microwave radiation. The amplifier module works by providing a set of amplifiers that exhibit a gain that is greater than the total loss experienced at the components that divide the input signal and then combine the output signals. For example, if each amplifier in the array has a gain of 10 dBm, it is viable to use conventional power splitters and combiners to obtain an output microwave signal with substantially higher power than is provided by conventional electrosurgical generators.

Abstract: An electrosurgical instrument end effector includes an active electrode received by an insulating material, the active electrode including a primary suction aperture which provides access to a primary fluid channel extending from the active electrode, through the insulating material, to a lumen. The lumen is arranged to carry fluid to and from a surgical site when in use. The end effector further includes at least one additional fluid channel providing alternative access to the primary fluid channel from the active electrode, wherein the at least one additional fluid channel bypasses the primary suction aperture.

Abstract: Various systems and methods for controlling an ultrasonic surgical instrument according to the location of tissue grasped within an end effector are disclosed. A control circuit can be configured to apply varying power levels, via a generator, to an ultrasonic transducer driving an ultrasonic electromechanical system to oscillate an ultrasonic blade. Further, the control circuit can measure impedances of the ultrasonic transducer corresponding to the varying power levels and determine a location of tissue positioned within the end effector according to a difference between the impedances of the ultrasonic transducer relative to a threshold.

Abstract: A surgical instrument includes a housing, a shaft extending distally from the housing, an end effector assembly at a distal end portion of the shaft, and a drive assembly. The drive assembly includes a movable handle, a carriage operably coupled to the movable handle, an inner drive operably coupled to the end effector assembly, and a spring assembly operably coupling the carriage and the inner drive. The spring assembly includes inner and outer coil springs arranged in a nested configuration. Initial actuation of the movable handle slides the carriage such that the spring assembly transfers the sliding of the carriage into translation of the inner drive to apply a jaw force by the end effector assembly. Subsequent actuation of the movable handle slides the carriage to compress the spring assembly to substantially maintain a position of the inner drive, thereby controlling the jaw force.