Abstract: A tool assembly for use with an electrosurgical device for cutting tissue includes a base portion, a return lead, an electrical insulator, a center pin, and an active lead. The center pin extends from the base portion and through a lumen of the electrical insulator. The active lead is securely fixed to the base portion and extends between the base portion and a distal portion of the center pin such that a portion of the active lead extends around the distal portion of the center pin and first and second segments of the active lead are spaced apart from the return lead. Upon activation, electrosurgical energy is transmitted from the active lead through tissue to the return lead to cut tissue in contact with the active lead.

Abstract: An electrosurgical smoke evacuation pencil includes a handle housing having a proximal end portion and a distal end portion, the handle housing defining a first lumen therethrough. The electrosurgical pencil also includes a nozzle disposed within the first lumen and defining a second lumen, the nozzle being movable relative to and within the handle housing and extending proximally past the proximal end portion of the handle housing. The electrosurgical pencil may further include a swivel connector coupled to the distal end portion of the handle housing, the swivel connector configured to couple to a suction source. The electrosurgical pencil includes a hub assembly securedly disposed within the second lumen, the hub assembly including a conductive tube configured to couple to a source of electrosurgical energy, and an electrode slidably disposed within the conductive tube, the electrode being movable relative to and within the conductive tube.

Abstract: One aspect relates to a conductive polymer composite based sensor, a detection unit comprising such sensor, a method for manufacturing a conductive polymer composite based sensor, and a use of the conductive polymer composite based sensor or the detection unit. The conductive polymer composite based sensor includes a substrate and a sensor material. The sensor material includes an insulating polymer matrix component and an electrically conductive component dispersed in the polymer matrix component to form the conductive polymer composite. The sensor material is pre-strained and applied to the substrate to form the sensor.

Abstract: A surgical system includes an active terminal, a return terminal, an active electrode, a return electrode, an active plug configured to connect to the active terminal, and a return plug configured to connect to the return terminal. The return plug is coupled to the return electrode and coupled between the active plug and the active electrode. The return plug is configured to break an electrical connection between the active plug and the active electrode when the return plug is not connected to the return terminal and to establish an electrical connection between the active plug and the active electrode when the return plug is connected to the return terminal.

Abstract: Provided herein are new compositions, methods, and devices to treat cancer through a combination of immunologic chemotherapeutic agents and ablation techniques. These compositions can include immune checkpoint inhibitors, cytokines and nucleic acid drugs that aid in eliciting an immune response to treat the tumor. The administration of these compositions in addition to various ablating techniques provides a presentation of the cancer cell antigens to the immune system and the immunologic targeting of the cancer.

Abstract: Systems, devices, and methods for electroporation ablation therapy are disclosed, with a protection device for isolating electronic circuitry, devices, and/or other components from a set of electrodes during a cardiac ablation procedure. A system can include a first set of electrodes disposable near cardiac tissue of a heart and a second set of electrodes disposable in contact with patient anatomy. The system can further include a signal generator configured to generate a pulse waveform, where the signal generator coupled to the first set of electrodes and configured to repeatedly deliver the pulse waveform to the first set of electrodes. The system can further include a protection device configured to selectively couple and decouple an electronic device to the second set of electrodes.

Abstract: Methods and systems are disclosed for removing a tattoo from a subject's skin by application of a cold plasma that is delivered via a liquid-gas mixture. The plasma can be delivered in the form of gas bubbles, in which at least a portion of gas is in the form of a plasma.

Abstract: An elongate electrode is configured to flex and generate plasma to incise tissue. An electrical energy source operatively coupled to the electrode is configured to provide electrical energy to the electrode to generate the plasma. A tensioning element is operatively coupled to the elongate electrode. The tensioning element can be configured to provide tension to the elongate electrode to allow the elongate electrode to flex in response to the elongate electrode engaging the tissue and generating the plasma. The tensioning element operatively coupled to the flexible elongate electrode may allow for the use of a small diameter electrode, such as a 5 ?m to 20 ?m diameter electrode, which can allow narrow incisions to be formed with decreased tissue damage. In some embodiments, the tensioning of the electrode allows the electrode to more accurately incise tissue by decreasing variations in the position of the electrode along the incision path.

Abstract: An end effector of an electrosurgical device may include a discharge port, an aspiration port, two electrodes, and a diverter formed from a porous material. The diverter includes a matrix having voids to receive fluid from the discharge port. A releasable diverter assembly may include an assembly body configured to receive a pair of electrodes and a diverter composed of a porous material. A shaft assembly of an electrosurgical device may include two electrodes and two fluid cannulae. Each cannula may be disposed proximate to a surface of each of the electrodes. An end effector of an electrosurgical device may include a fluid discharge port, two electrodes, and a diverter disposed therebetween. A proximal edge of the diverter may form a secant line with respect to the end of the discharge port so that fluid emitted by the discharge port is disposed on a surface of the diverter.

Abstract: An end effector of an electrosurgical device may include a first body, a first electrode on the left side of the first body, and a second electrode on the right side of the first body. The first and second electrodes may be configured to receive electrosurgical energy to treat tissue in a target treatment zone. The end effector may also include a fluid aspiration port in fluid communication with a fluid path. The fluid aspiration port may be configured to remove a material from the target treatment zone.

Abstract: This disclosure relates to using stereo-thermo-lesioning (STL) to create lesions at one or more locations in the patient's nervous system at the patient's bedside without general anesthesia. A method that uses STL to treat a patient's neurological condition includes: using a plurality of stereotactically-implanted thermo-coupled multi-contact electrodes to record conduction data within a predetermined theoretical zone of activity within the patient's neurological tissue; detecting abnormal neurological activity of a neurological condition within the conduction data and localize a portion of the predetermined theoretical zone of activity that is responsible for a primary organization of the abnormal neurological activity; creating a lesion at the portion of the predetermined theoretical zone of activity that is responsible for a primary organization of the abnormal neurological activity using at least one contact of the plurality of thermo-coupled multi-contact electrodes.

Abstract: Systems and methods for controlling energy delivered to an area of tissue during a treatment procedure are provided. The system includes a device for delivering energy to the area of tissue; an energy generator for generating and supplying energy to the device; and a controller for controlling an amount of energy generated by the energy generator and delivered to the area of tissue by the device. Controlling the amount of energy delivered to the area of tissue alters a primary zone of the area of tissue to a first level, alters a secondary zone to a second level, alters a tertiary zone to a third level, or a combination thereof, where the first level, the second level, the third level, or a combination thereof is predetermined, and where a coverage area of the primary zone, the secondary zone, the tertiary zone, or a combination thereof is also predetermined.

Abstract: An electrosurgical generator having connectors for an electrosurgical instrument including a high-voltage generator electrically connected to the connectors and produces a high-frequency alternating current in its activated state and output said high-frequency alternating current via the connectors. The electrosurgical generator has an effective power determination unit including a phase shift determination unit that supplies an output signal representing a phase shift between the current and the voltage of an alternating current output during operation. The phase shift determination unit produces a pulsed DC voltage signal, in which the pulse width reflects a time difference between the zero crossings of the current and the voltage—and consequently the phase shift—and to process the pulsed DC voltage signal by way of a low-pass filter to form a low-pass filter output signal, the magnitude of which depends on the pulse width of the pulses of the pulsed DC voltage signal.

Abstract: An end effector assembly of a forceps includes a first jaw with a tissue sealing surface and an electrode on the sealing surface, and a second jaw with a tissue sealing surface and an electrode on the sealing surface. The first jaw and the second jaw move between an open position and a closed position. The sealing surface of at least one of the first jaw and the second jaw has a rigid medial section and flexible lateral sections.

Abstract: Methods for treating dyspnea with therapeutic renal neuromodulation and associated system and methods are disclosed herein. One aspect of the present technology, for example, is directed to methods that block, reduce, and/or inhibit renal sympathetic nerve activity to achieve a reduction in central sympathetic tone. Renal sympathetic nerve activity may be altered or modulated along the afferent and/or efferent pathway. The achieved reduction in central sympathetic tone may carry therapeutic benefits for patients with dyspnea.

Abstract: An electrosurgical system includes an electrosurgical generator having active and return terminals, an electrosurgical instrument including an active electrode, a return instrument including a return electrode, an active plug configured to connect to the active terminal of the generator, a return plug configured to connect to the return terminal of the generator, an active cable extending from the return plug to the electro surgical instrument, a return cable extending from the return plug to the return instrument, a connector cable extending from the active plug to the return plug, and a mechanical switch mechanism disposed within the return plug. The mechanical switch mechanism has a disengaged position in which the active plug is electrically disconnected from the active cable and an engaged position in which the active plug is in electrical communication with the active cable.

Abstract: A method and system for automated and semi-automated predictable, consistent, safe, effective, and lumen-specific and patient-specific cryospray treatment of airway tissue in which treatment duration is automatically set by the system following entry of patient information and treatment location information into the system by the user, and treatment spray is automatically stopped by the system when the automatically selected treatment duration has been achieved as determined by the system.

Abstract: A method and system for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to a cold plasma is described herein. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.

Abstract: A percutaneous catheter system for use within the human body and an ablation catheter for ablating a selected tissue region within the body of a subject. The percutaneous catheter system can include two catheters that are operatively coupled to one another by magnetic coupling through a tissue structure. The ablation catheter can include electrodes positioned within a central portion. The ablation catheter is positioned such that the central portion of a flexible shaft at least partially surrounds the selected tissue region. Each electrode of the ablation catheter can be activated independently to apply ablative energy to the selected tissue region. The ablation catheter can employ high impedance structures to change the current density at specific points. Methods of puncturing through a tissue structure using the percutaneous catheter system are disclosed. Also disclosed are methods for ablating a selected tissue region using the ablation catheter.

Abstract: An energy surgical instrument includes first and second grasping pieces for grasping a blood vessel. At least one of the grasping pieces is designed to apply treatment energy to a grasped blood vessel. The instrument also includes a processor designed to set a wall thickness of the blood vessel, and a grasping force adjuster designed to adjust a grasping force applied by the first and second grasping pieces. A first grasping force is applied when the wall thickness set by the processor is larger than a predetermined thickness, and a second grasping force, which is larger than the first grasping force, is applied when the wall thickness set by the processor is equal to or smaller than the predetermined thickness. A treatment method includes applying treatment energy to a blood vessel grasped by the first and second grasping pieces of the instrument to seal the blood vessel.