Abstract: Multi-dose preservative-free ocular fluid delivery devices are provided. The fluid delivery device includes a fluid dispensing system and a fluid package for storing a liquid therein and supplying said liquid to the dispensing system. The dispensing system comprises an elongated chamber which includes a check valve which defines a frontal closure to the chamber. The valve is normally closed and hermetically seals the chamber. The dispenser includes a vibration motor that induces oscillations to the chamber and to the fluid within. The oscillations of the chamber impart momentum to the fluid stored in the chamber which in turn imparts force that cyclically opens the valve to dispense streams or liquid droplets. Fluid is dispensed only when the motor oscillates while otherwise the valve is hermetically closed. Preferably, the fluid package and check valve are included in a disposable reservoir assembly.

Abstract: An intermittent hydrophilic urinary catheter (1) with a hydrophilic coating (9) and comprising a plurality of drainage openings (5) is provided. The outer surface (8) of the tubular portion (1a) forms a projection (410) encircling the openings in the outer surface and extending above the hydrophilic surface (411) when the hydrophilic material is in the non-swelled condition.

Abstract: A dressing for treating a tissue site with negative pressure including a tissue interface, a cover, a chamber wall, and a base. The cover may be adapted to be sealed to epidermis proximate the tissue site. The chamber wall may define a pump chamber, wherein the pump chamber may be adapted to be fluidly coupled to the tissue interface. The base may extend from the chamber wall, wherein the base may be fluidly sealed to the cover. The dressing may include an intake valve and an exhaust valve fluidly coupled to the pump chamber. The pump chamber may be compressed to evacuate fluid from the pump chamber through the exhaust valve. The pump chamber may then be expanded to draw’ fluid through the intake valve from the tissue interface. This supplies a negative pressure to the tissue interface which may be adapted to distribute negative pressure across the tissue site.

Abstract: A syringe for delivery of a medical liquid to a container has a body with proximal end, a frustoconical distal end, and a cylindrical sidewall extending between the proximal end and the distal end along a longitudinal axis. The syringe includes a nozzle at a distal portion of the frustoconical distal end of the syringe, the nozzle having a throughbore providing fluid communication between an interior volume of the syringe and a medical connector configured to be connected to the nozzle. The nozzle includes a plurality of longitudinal ribs formed on an inner surface of the nozzle. The syringe is designed so that the plurality of longitudinal ribs directs a flow of a medical fluid along an inner surface of the frustoconical distal end and along an interior surface of the cylindrical sidewall of the syringe under a Coand? effect. Syringe and connector assemblies and methods for reducing a number of bubbles formed in a medical fluid during a syringe filling procedure are also described.

Abstract: A system suitable for collecting and transporting urine away from the body of a person or animal may include an urine collecting assembly having a body, a sealing flange, and a reservoir within the body and partially defined by the sealing flange. The sealing flange can define an opening such that the interior of the body is accessible via the opening. A peripheral edge of the opening can be configured to seal around a shaft of a penis of a user disposed through the opening. The urine collecting assembly can also include an outlet in fluidic communication with the reservoir. The urine collecting assembly can be arranged such that a fluid can flow into the body from the urethral opening of the user's penis, collect in the reservoir, and flow out of the outlet.

Abstract: The present disclosure provides in part improved apparatuses, systems, and methods for providing therapy to a wound. A system can include a first power source configured to power an electronic component and a second power source configured to power the electronic component in place of the first power source. Responsive to a first condition, the second power source can power the electronic component in place of the first power source. In some cases, the system can include a pressure source that is configured to provide negative pressure to a wound dressing positioned over a wound. The wound dressing can support the first power source or the second power source.

Abstract: A urine incontinence pad has an absorbent core having a first core layer and a fluid control layer. The absorbent core has a varying thickness profile as seen in the longitudinal direction, with the intermediate portion having a first thickness under a load of 0.5 kPa and a first compressed thickness under a load of 2.5 kPa. The rear and front portions each have a second thickness under a load of 0.5 kPa and a second compressed thickness under a load of 2.5 kPa, wherein the second thickness is from 37% to 15% of the first thickness, the second compressed thickness is from 37% to 15% of the first compressed thickness and a ratio between the first and the second compressed thickness under a load of 2.5 kPa is equal or greater than a ratio between the first and the second thickness, under a load of 0.5 kPa.

Abstract: A therapeutic device for extended release drug delivery including a refillable reservoir configured to receive a therapeutic agent and having an outlet for delivery of the therapeutic agent to a patient from the reservoir over an extended period. A porous structure is coupled near the outlet of the reservoir, the porous structure formed of sintered material. A barrier layer is coupled to the reservoir on or adjacent a surface of the porous structure such that the therapeutic agent passes through both the porous structure and the barrier layer upon delivery from the reservoir through the outlet. The porous structure is tuned to deliver the therapeutic agent at a diffusion rate and the barrier layer is adapted to block passage of particles having an average particle size within an average particle size range that is outside an average particle size range blocked by the porous structure. Related methods and systems are provided.

Abstract: Disclosed herein are several embodiments of a wound treatment apparatus employing a wound dressing for negative pressure wound therapy and methods of using the same. Some embodiments are directed to improved wound dressing to be applied to a wound site, for example a wound dressing including a three-dimensional filter element, and methods of using the same.

Abstract: Systems, catheters, and methods for accessing and treating along the central nervous system are disclosed including sampling systems. An example sampling system may include a filter cassette designed to filter cerebrospinal fluid. The filter cassette may have an inlet region configured to be coupled to a catheter and configured to receive cerebrospinal fluid, one or more filters, and an outlet region configured to be coupled to an outlet of the catheter and to direct filtered cerebrospinal fluid to the catheter. A sampling port may be in fluid communication with the filter cassette. The sampling port may have a first end region configured to receive cerebrospinal fluid, a stopcock, a syringe port, and a second end region. The stopcock may be configured to shift between a first position where cerebrospinal fluid is directed from the first end region to the second end region and a second position where cerebrospinal fluid is directed from the first end region to the syringe port.

Abstract: To prevent or suppress roughness of the skin of a wearer by configuring an absorbent article so as to quickly absorb a body fluid into an absorber, for example, configuring a diaper so as to quickly absorb loose stool into an absorber. An absorbent article includes a liquid-holding absorber and a liquid pervious top sheet on a skin-facing surface side of the absorber. An absorbent Q mainly containing glycerin is provided on an intermediate sheet that transfers at least a body fluid that has passed through the top sheet to the absorber.

Abstract: A wound therapy system includes an instillation fluid canister configured to contain an instillation fluid, a pump fluidly coupled to the instillation fluid canister and operable to deliver the instillation fluid from the instillation fluid canister to a wound, a user interface configured to receive user input indicating one or more geometric attributes of the wound, and a controller electronically coupled to the pump and the user interface. The controller is configured to determine a volume of the wound based on the user input, determine a volume of the instillation fluid to deliver to the wound based on the volume of the wound, and operate the pump to deliver the determined volume of the instillation fluid to the wound.

Abstract: A negative pressure wound treatment (NPWT) system including a NWPT therapy unit and a wound dressing configured to overlay a wound bed. The NPWT system includes a first length of tubing comprising a first end and a second end, the first end of the first length of tubing coupled to the NWPT therapy unit and the second end of the first length of tubing having a first coupling half, as well as a second length of tubing having a first end and second end, the first end of the second length of tubing coupled to the wound dressing and the second end of the second length of tubing having a second coupling half. The NPWT system includes an inline filter comprising a sintered polymer and a superabsorbent material, and an inline coupling, wherein the inline coupling is configured to operably couple and de-couple the NPWT therapy unit and wound dressing.

Abstract: A face mask or body cover assembly, including for lips, can include a band and a lip-contacting portion comprising a plurality of plastic liners, a skin healing formulation, and an ice pack gel solution filling. The face mask assembly can self-adhere to a patient's face. The skin healing formulation can include a first active botanical compound and a second active botanical compound that can function as an analgesic, an antimicrobial, an activity, an anti-inflammatory and/or an antioxidant.

Abstract: A thermal protection system configured for use with a dialysate container or bag in a dialysis system is disclosed. The thermal protection system being configured so that when the dialysate container is subjected to a temperature greater than a predetermined temperature such as, when the dialysate container is heated within a microwave oven, the thermal protection system is configured to (i) prevent the flow of dialysate from the bag, (ii) indicate that the dialysate container has been subjected to a temperature greater than the predetermined temperature, or (iii) a combination thereof. In one embodiment, the thermal protection system is a circular hollow ring positioned within an exit port of the bag, the ring melting upon reaching the predetermined temperature to block the flow of dialysate. Alternatively, and/or in addition, the thermal protection system may be a thermally sensitive dye configured to change color upon being subjected to the predetermined temperature.

Abstract: Disclosed herein are embodiments of a wound treatment apparatus with electronic components integrated within a wound dressing. In some embodiments, a wound dressing apparatus can comprise a wound dressing. The wound dressing can comprise an absorbent material, an electronics unit comprising a negative pressure source, the electronics unit integrated within the wound dressing and at least partially encapsulated by a flexible film. The electronics unit can include translucent or transparent components that allow light to travel through to reach adhesives or coatings on the electronic components that would otherwise be obscured.

Abstract: An absorbent article includes an absorbent core sandwiched between a topsheet and a backsheet, the article being arranged along a longitudinal axis and a transversal axis extending in a perpendicular direction and the article defining a front portion, a back portion and a crotch portion, wherein the absorbent core includes an absorbent component enclosed by a core cover including an upper side and a lower side and the core is formed with a sealing arrangement for joining the upper and lower sides including two channel sealings extending along the longitudinal axis in said crotch portion and defining a first channel sealing width and a second channel sealing width, respectively. Furthermore, the absorbent article includes at least one wetness indicator having a longitudinal extension and being positioned generally only in the front portion, only in the back portion, or in both the front portion and the back portion.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment. A wound dressing apparatus can comprises a wound contact layer, at least one absorbent layer, an electronics unit comprising a negative pressure source unit, and a cover layer. The electronics unit can comprise a plurality of sensors positioned on a printed circuit board and an inlet protection mechanism of the negative pressure source unit comprises a first recess in fluid communication with a first sensor and the outlet or exhaust mechanism negative pressure source unit comprises a second recess in fluid communication with a second sensor.

Abstract: In some embodiments, a negative pressure wound closure system and methods for using such a system are described. Certain disclosed embodiments facilitate closure of the wound by preferentially contracting to exert force on the tissue. Some embodiments may utilize a collapsible structure with a plurality of cells.

Abstract: A transdermal drug delivery device includes a reservoir, a transdermal membrane, a piston, a control rod, a spring, and a rotational cam. The reservoir is configured to hold a formulation. The transdermal membrane is configured to allow the formulation from the reservoir to pass therethrough. The piston is configured to move into the reservoir. The control rod is attached to the piston and includes a plurality of teeth thereon. The spring is configured to apply force to the control rod in the direction of the reservoir. The rotational cam has a first camming surface and a second camming surface that are configured to engage with the plurality of teeth. The rotational cam, when rotated, is configured to disengage the first camming surface from a first tooth of the plurality of teeth, thereby allowing the spring to advance the piston into the reservoir to expel the formulation onto the transdermal membrane.