Abstract: An absorbent article includes an absorbent core sandwiched between a topsheet and a backsheet, the article being arranged along a longitudinal axis and a transversal axis extending in a perpendicular direction and the article defining a front portion, a back portion and a crotch portion, wherein the absorbent core includes an absorbent component enclosed by a core cover including an upper side and a lower side and the core is formed with a sealing arrangement for joining the upper and lower sides including two channel sealings extending along the longitudinal axis in said crotch portion and defining a first channel sealing width and a second channel sealing width, respectively. Furthermore, the absorbent article includes at least one wetness indicator having a longitudinal extension and being positioned generally only in the front portion, only in the back portion, or in both the front portion and the back portion.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment. A wound dressing apparatus can comprises a wound contact layer, at least one absorbent layer, an electronics unit comprising a negative pressure source unit, and a cover layer. The electronics unit can comprise a plurality of sensors positioned on a printed circuit board and an inlet protection mechanism of the negative pressure source unit comprises a first recess in fluid communication with a first sensor and the outlet or exhaust mechanism negative pressure source unit comprises a second recess in fluid communication with a second sensor.

Abstract: In some embodiments, a negative pressure wound closure system and methods for using such a system are described. Certain disclosed embodiments facilitate closure of the wound by preferentially contracting to exert force on the tissue. Some embodiments may utilize a collapsible structure with a plurality of cells.

Abstract: A transdermal drug delivery device includes a reservoir, a transdermal membrane, a piston, a control rod, a spring, and a rotational cam. The reservoir is configured to hold a formulation. The transdermal membrane is configured to allow the formulation from the reservoir to pass therethrough. The piston is configured to move into the reservoir. The control rod is attached to the piston and includes a plurality of teeth thereon. The spring is configured to apply force to the control rod in the direction of the reservoir. The rotational cam has a first camming surface and a second camming surface that are configured to engage with the plurality of teeth. The rotational cam, when rotated, is configured to disengage the first camming surface from a first tooth of the plurality of teeth, thereby allowing the spring to advance the piston into the reservoir to expel the formulation onto the transdermal membrane.

Abstract: Disclosed is an absorbent article comprising a core chassis and a leg gasketing system comprising a pair of wearer facing cuff regions comprising an inner cuff sealing and inner cuff free edge positioned inward from the inner cuff sealing, wherein the inner cuff sealing bonds the cuff material and a topsheet, and an inner cuff elastic element is disposed adjacent the inner cuff free edge; a pair of garment facing cuff regions formed by inwardly extending the cuff material over a garment facing side of the core chassis, and a pair of outer cuff elastic elements disposed on wearer facing cuff regions or garment facing cuff regions; and wherein the absorbent article has a Worn Leg Opening (WLO) of from about 300 mm to about 450 mm, a Minimum Leg Opening (MLO) of from about 225 mm to about 300 mm, and a ratio of WLO/MLO of from about 1.5 to about 1.7.

Abstract: Filtering device for filtering cerebrospinal fluid are disclosed. An example filtering device may include a filter housing having an inlet for receiving cerebrospinal fluid from a patient and an outlet for returning filtered cerebrospinal fluid to the patient. The filter housing may include a plurality of layers coupled together and defining a fluid pathway therein between the inlet and the outlet. A filtering section may be defined within the filter housing along the fluid pathway. The filtering section may include a widened region of the fluid pathway that is configured to slow the passage of fluid therethrough.

Abstract: Embodiments of a negative pressure wound closure system and methods for using such a system are described. Certain disclosed embodiments facilitate closure of a wound by preferentially exerting a negative pressure on tissue. Some embodiments may utilize a collapsible sheet with a plurality of cells.

Abstract: An absorbent core comprising: a front portion; a back portion; a middle portion positioned between the front portion and the back portion; and a longitudinal axis extending along a length of said core and crossing said front, middle and back portions, the absorbent core having a width extending perpendicular to said length and a perimeter comprising at least two opposing ends and at least two opposing sides positioned between said ends, said core being a multi-layer core comprising at least two distinct core layers, wherein a first core layer comprises a channel having a first shape and a second core layer comprises a further channel having a second shape and wherein the first and second core layers are disposed one on top of the other such that a third channel shape is formed along said core length and width, and wherein said first and second shapes are substantially the same and are different to said third shape.

Abstract: The present disclosure provides in part improved apparatuses, systems, and methods for providing therapy to a wound. A system can include a first power source configured to power an electronic component and a second power source configured to power the electronic component in place of the first power source. Responsive to a first condition, the second power source can power the electronic component in place of the first power source. In some cases, the system can include a pressure source that is configured to provide negative pressure to a wound dressing positioned over a wound. The wound dressing can support the first power source or the second power source.

Abstract: A device for transferring a liquid from a first vial to a second vial is disclosed having a dome portion configured to create an air flow when activated by compression and re-expansion, and a support body tightly supporting the dome portion to form a chamber with air therein. The support body includes first and second vial seats, and a transfer conduit. The first and second vial seats are arranged to receive the first and second vials. When the first and second vials are received in the first and second vial seats, the transfer conduit is arranged to establish a fluid connection between the first vial and the second vial. Upon activation of the dome portion, air is delivered into the first vial, thereby creating a pressure rise in the first vial which causes the liquid to transfer from the first vial to the second vial through the transfer conduit.

Abstract: Device (1) for filling blood products (12) into at least two administration containers (2), comprising at least one receptacle (3) for dispensing the blood product (12) into the device (1), a channel system (4, 7, 8, 17) connected to carry fluid to the administration containers (2), and an air exhaust assembly (10, 11, 15), where the device (1) further comprises a plate-shaped component (6) in which the channels (7, 8, 17) of the channel system run, through which the administration containers (2) can be filled in parallel with equal volumes of the blood product (12).

Abstract: The invention relates to a flexible container/multi-chamber container with selective dissolved gas content for stabilizing at least one compound of a medical product having a selective gas requirement for remaining stable, comprising a solution comprising the at least one compound and a fil material from which the container is made that provides for high gas-barrier for the said gas. The at least one compound may be selenium in the form of Se(IV) and is preferably selected from the group consisting of sodium selenite, selenous acid and selenium dioxide. The selective gas may be oxygen, and the headspace of the oxygen maintains the solution to comprise dissolved oxygen (DO) at a level of 0.5 ppm to 8 ppm.

Abstract: The invention relates to a disposable absorbent pant comprising a central chassis and elasticized front and rear belt. The central chassis comprises an absorbent core with an absorbent layer. The absorbent layer comprises a continuous channel formed therein.

Abstract: Multi-dose preservative-free ocular fluid delivery devices are provided. The fluid delivery device includes a fluid dispensing system and a fluid package for storing a liquid therein and supplying said liquid to the dispensing system. The dispensing system comprises an elongated chamber which includes a check valve which defines a frontal closure to the chamber. The valve is normally closed and hermetically seals the chamber. The dispenser includes a vibration motor that induces oscillations to the chamber and to the fluid within. The oscillations of the chamber impart momentum to the fluid stored in the chamber which in turn imparts force that cyclically opens the valve to dispense streams or liquid droplets. Fluid is dispensed only when the motor oscillates while otherwise the valve is hermetically closed.

Abstract: A mobile negative pressure wound therapy (NPWT) device is described having an inlet; a canister in fluid flow connection with the inlet; a pump having a pump casing with a pump inlet in fluid flow connection with the canister in the canister, and a pump outlet for output of air transported through the pump; an elastomeric jacket at least partly enclosing the pump, the elastomeric jacket being configured to define a flow channel having a first end arranged to receive air output by the pump outlet and a second end spaced apart from the first end for discharging the air output by the pump outlet following passage through the flow channel; a control unit for controlling operation of the mobile NPWT device; a battery arrangement for powering the mobile NPWT device; and a housing enclosing at least the pump, the elastomeric jacket, the control unit, and the battery arrangement.

Abstract: Multi-dose preservative-free ocular fluid delivery devices are provided. The fluid delivery device includes a fluid dispensing system and a fluid package for storing a liquid therein and supplying said liquid to the dispensing system. The dispensing system comprises an elongated chamber which includes a check valve which defines a frontal closure to the chamber. The valve is normally closed and hermetically seals the chamber. The dispenser includes a vibration motor that induces oscillations to the chamber and to the fluid within. The oscillations of the chamber impart momentum to the fluid stored in the chamber which in turn imparts force that cyclically opens the valve to dispense streams or liquid droplets. Fluid is dispensed only when the motor oscillates while otherwise the valve is hermetically closed.

Abstract: A canister connection system for a negative pressure wound therapy system. The canister connection system includes an attachment fixture removably connected to a pump unit. The attachment fixture includes a first engaging mechanism disposed adjacent its first end configured to engage a corresponding first engaging mechanism of the canister and a second engaging mechanism disposed adjacent its second end for engaging a corresponding second engaging mechanism of the canister for removably connecting the canister to the pump unit.

Abstract: A reconstitution device includes a body, a first piercing member located at a first end of the body, and a receptacle located at the second end of the body. The receptacle includes a collar configured to engage a vial, and a cap extending from the collar and holding a second piercing member. The second piercing member is disposed within the collar. The reconstitution device includes a first fluid pathway formed within and extending from the first piercing member to the second piercing member. The reconstitution device includes a second fluid pathway formed within and extending from the second piercing member to a portion of the body between the first piercing member and the second piercing member.

Abstract: A closed transfer system for transferring metered dose of a beneficial agent from a flexible primary container to a second reservoir or to a patient. The system can be configured to transfer multiple doses.

Abstract: A new and improved NPWT bandage which is simple, inexpensive, easy-to-use, small in size (including having a low profile), is atraumatic to the wound during use, has improved pump efficiency, incorporates an automatic pressure indicator for indicating the level of negative pressure created, and provides an automatic pressure limiter for limiting the level of negative pressure created.