Patents Examined by Sharmila G. Landau
  • Patent number: 10711215
    Abstract: A method to generate dioxolanes from renewable feedstocks, and more specifically, these oxygenated hydrocarbons can be used as gasoline-range fuels and diesel additives.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: July 14, 2020
    Assignee: The Government of the United States of America as represented by the Secretary of the Navy
    Inventors: Benjamin G. Harvey, Heather A. Meylemans
  • Patent number: 10696944
    Abstract: A microfluidic system for causing perturbations in a cell membrane, the system including a microfluidic channel defining a lumen and being configured such that a cell suspended in a buffer can pass therethrough, wherein the microfluidic channel includes a cell-deforming constriction, wherein a diameter of the constriction is a function of the diameter of the cell.
    Type: Grant
    Filed: October 17, 2012
    Date of Patent: June 30, 2020
    Assignee: Massachusetts Institute of Technology
    Inventors: Armon R. Sharei, Andrea Adamo, Robert S. Langer, Klavs F. Jensen
  • Patent number: 10653729
    Abstract: Probiotic compositions that comprise one or more bacteria species in spore form, a thickener to form a stabilized suspension and to preferably act as a prebiotic, one or more acids or salts of acids, and optionally a water activity reducer. A system for delivering probiotic compositions by gravity feed or non-contact pump to a point of consumption by a plant or animal, preferably in conjunction with acidified drinking water, comprising a collapsible container with attachable tubing that prevent contamination of the probiotic composition within the container. Delivery may be actuated in response to a timer, motion detector, fluid level sensor, RFID tag, or other mechanism to periodically or continuously dispense a dosage of probiotic composition directly to the soil surrounding a plant or to the water or feed for an animal. A method for increasing beneficial bacteria in an animal's GIT comprises adding probiotics to acidified drinking water.
    Type: Grant
    Filed: October 27, 2014
    Date of Patent: May 19, 2020
    Assignee: NCH Corporation
    Inventors: Scott Martell Boyette, Judith Gayle Pruitt, John Knope, Adrian Denvir, Charles Greenwald, Alex Erdman
  • Patent number: 10624377
    Abstract: The present invention relates to edible webs comprising microorganisms, such as probiotics. In particular, the present invention relates to an edible web having microorganisms, such as bacteria, probiotic bacteria, bacteriophages or viruses printed thereon, e.g. by the use of inkjet printing. In addition the invention relates to methods of producing such edible webs, to various products comprising the edible webs as well as to use of the edible webs comprising microorganisms.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: April 21, 2020
    Assignee: Societe des Produits Nestle S.A.
    Inventor: Martinas Kuslys
  • Patent number: 10602752
    Abstract: An infant formula for preventing gastro-esophageal reflux is disclosed comprising whey protein and/or casein, a galactomannan thickener, and a fermented milk-derived product.
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: March 31, 2020
    Assignee: N.V. NUTRICIA
    Inventors: Marie Thomas, Francis Lecroix, Evan Abrahamse, Houkje Bouritius
  • Patent number: 10513717
    Abstract: The present invention relates to enzymes which possess desaturase, conjugase, epoxidase and/or hydroxylase activity that can be used in methods of synthesizing fatty acids.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: December 24, 2019
    Inventors: Katherine Damcevski, Karen Glover, Allan Green, Victoria S. Haritos, Irene Horne, Surinder Pal Singh, Craig C. Wood, Xue-Rong Zhou
  • Patent number: 10501773
    Abstract: In some embodiments, the invention provides methods for detecting and/or classifying an anticoagulant at a therapeutically relevant amount or higher in a patient, including subjecting a sample of a control blood component (known not to contain the anticoagulant) to a clotting assay in the presence of a Factor Xa reagent to obtain a control clotting measurement; and subjecting a sample of a blood component from a patient suspected of having the anticoagulant to the clotting assay in the presence of the Factor Xa reagent to obtain a patient clotting measurement, wherein the patient clotting measurement sample greater than the control clotting measurement indicates the presence of the anticoagulant at a therapeutically relevant amount or higher in the patient. In some embodiments, the invention includes methods for classifying an anticoagulant as an anti-Factor Xa or a direct thrombin inhibitor anticoagulant using a clotting assay in the presence of an ecarin reagent.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: December 10, 2019
    Assignee: Haemonetics Corporation
    Inventors: Fowzia S. Zaman, Marc Doubleday
  • Patent number: 10494599
    Abstract: The invention is comprised within automated devices for cell culture. The invention relates to a cell culture method and system which allows modifying in a controlled manner the density and the number of cells in a culture. Specifically, the present invention relates to an iterative method the number of iteration steps of which is modified depending on the demand for the density and the number of cells necessary for the culture duration.
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: December 3, 2019
    Assignee: ALGARIS CELL S.L.
    Inventors: David Horna Tomas, Miguel Costa Ferrando
  • Patent number: 10479969
    Abstract: Bioreactors and methods for cultivating microalgae under heterotrophic growth conditions using fruit wastewater as a carbon source are provided herein. The heterotrophic growth conditions include low irradiance of light sufficient to initiate light-activated metabolism, but not photosynthesis. The methods provide a cost effective and environmentally friendly solution for converting wastewater from dried fruit and wine industries into products like biofuels.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: November 19, 2019
    Inventors: Jane Kim, Chung-Soon Im
  • Patent number: 10450237
    Abstract: The present invention relates to a novel phosphate solubilizing strain of Penicillium bilaiae, which is a hybrid of Penicillium bilaiae ATCC 22348 and Penicillium bilaiae V08/021001, as well as compositions and methods for using the novel phosphate solubilizing strain to increase the availability of phosphorous for plant uptake from soil.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: October 22, 2019
    Inventors: David Greenshields, Shelagh Steckler, Kari Priest, Caressa Caldwell, Michael Frodyma
  • Patent number: 10421949
    Abstract: Provided herein are methods of culturing an adherent mammalian cell in a shake tube using a plurality of microcarriers and batch re-feed perfusion, and various methods that utilize these culturing methods.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: September 24, 2019
    Assignee: Genzyme Corporation
    Inventors: Jianguo Yang, Yang Yang
  • Patent number: 10385317
    Abstract: The disclosure provides methods of making a red blood cell, plasma, and platelet products having a uniform dose and volume. The method comprises pooling a plurality of blood units, leukoreducing the blood and inactivating any pathogen contained therein. Plasma, RBCs, and platelets are then divided into uniform dose and volume units which have an extended shelf life.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: August 20, 2019
    Inventors: Beth Shaz, Christopher D. Hillyer
  • Patent number: 10364447
    Abstract: The present invention provides a method for producing ?-3 polyunsaturated fatty acids by culturing specific myxobacterial stains and myxobacterial strains suitable for said method.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: July 30, 2019
    Assignee: Universitat Des Saarlandes
    Inventors: Ernst Roemer, Rolf Müller, Ronald O. Garcia, Mark Stadler, Dominik Pistorius, Alexander Brachmann
  • Patent number: 10323226
    Abstract: A bacteria starter material for use in biomass generators without causing jamming of the feeder mechanism, particularly under high temperature and/or high humidity conditions, the starter material comprising one or more species of waste-decomposing bacteria, sucrose, and a soy based protein. Preferably, DI-PAC® sugar (sucrose and maltodextrin) and powdered KIKKOMAN® Soy Sauce are used as the sugar and protein ingredients. The starter material may also comprise a dried bran culture comprising Pseudomonas. The starter material ingredients are blended together and formed into a tablet or pellet having a particular shape, size, and hardness characteristics suitable for use in the feeder mechanism of a biomass generator.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: June 18, 2019
    Assignee: NCH Corporation
    Inventors: Judith G. Pruitt, Robert C. Pearce, III, Daniel Aberle, Charles J. Greenwald, Gabriel F. K. Everett
  • Patent number: 10324100
    Abstract: The present invention provides methods for quantifying an amount of plasmalogens in samples with high accuracy in an easy, convenient and inexpensive manner by using a hydrolysis processing to samples and a lipid extraction followed by the measurement using High Performance Liquid Chromatography (HPLC) with Evaporative Light Scattering Detector (ELSD) or Mass Spectrometer (MS), a fluorescence plate reader or a plate reader. The present invention also relates to a method for examining a subject by using the above method, a biomarker for disease detection, a method for using the biomarker for the disease detection, as well as a kit for the disease detection.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: June 18, 2019
    Assignee: Institute of Rheological Functions of Food
    Inventors: Takehiko Fujino, Shiro Mawatari
  • Patent number: 10324036
    Abstract: The invention relates to a porous planar cell capture system for use in determining the presence and/or amount of cells, for example, viable cells, in a liquid sample, and to methods of using such a cell capture system. The cell capture system contains a fluid permeable, planar membrane adopted to retain cells thereon, a fluid permeable support member that supports the membrane, and an optional register associated with the membrane.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: June 18, 2019
    Assignees: Charles River Laboratories, Inc., ReaMetrix Inc.
    Inventors: Norman R. Wainwright, Bala S. Manian, Eric Stimpson, Brian J. Kolonia, Robert K. Kolonia
  • Patent number: 10251387
    Abstract: The present invention is a method for enhancing the quality and survival of red blood cells during storage by depleting the red blood cells of both carbon dioxide and oxygen and maintaining 2,3-diphosphoglycerate acid levels.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: April 9, 2019
    Assignee: New Health Sciences, Inc.
    Inventors: Larry J. Dumont, Tatsuro Yoshida
  • Patent number: 10246727
    Abstract: The invention provides processes for the conversion of pyruvate obtained from sugars or other carbon sources, to valuable C5 materials such as levulinic acid, levulinate esters, valerolactone, and derivatives thereof.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: April 2, 2019
    Assignee: ARZEDA CORP.
    Inventor: Alexandre Luc Zanghellini
  • Patent number: 10246644
    Abstract: The present invention provides a method for preparing biodiesel, comprising: adding oil and fat, short-chain alcohol, water, and liquid lipase into a single-stage or multi-stage enzyme reactor; then separating the reaction fluid into an enzyme-containing heavy phase and a light phase; recovering and reusing the enzyme in the heavy phase; using the light phase for subsequent conversion by immobilized lipase; flowing the light phase and the short-chain alcohol into single-stage or multi-stage enzyme reactor containing an immobilized lipase; performing online dehydration during the whole reaction process or part of the reaction process.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: April 2, 2019
    Assignee: Tsinghua University
    Inventors: Wei Du, Dehua Liu, Luole Zhu
  • Patent number: 10232004
    Abstract: A pharmaceutical composition based on centella asiatica (Hydrocotyle asiatica L.) for the treatment of lower limb ulcers, including as active ingredients, centella asiatica and sodium acexamate in amounts producing a reciprocal synergistic effect when mixed with at least one adjuvant selected from a healing agent, an antibiotic agent and/or combinations thereof is described.
    Type: Grant
    Filed: April 9, 2014
    Date of Patent: March 19, 2019
    Inventor: Flor Lucía Montañez-Soto